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Volumn 21, Issue 8, 2016, Pages 769-785

Antigen Selection for Enhanced Affinity T-Cell Receptor-Based Cancer Therapies

Author keywords

mass spectrometry; oncology; review; T cell receptors; TCR

Indexed keywords

CANCER TESTIS ANTIGEN; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84981240512     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057116637837     Document Type: Review
Times cited : (15)

References (179)
  • 1
    • 84878802844 scopus 로고    scopus 로고
    • Immunity over Inability: The Spontaneous Regression of Cancer
    • Jessy T., Immunity over Inability: The Spontaneous Regression of Cancer. J. Nat. Sci. Biol. Med. 2011, 2, 43-49.
    • (2011) J. Nat. Sci. Biol. Med , vol.2 , pp. 43-49
    • Jessy, T.1
  • 2
    • 84941800472 scopus 로고    scopus 로고
    • Adaptive Immune Resistance: How Cancer Protects from Immune Attack
    • Ribas A., Adaptive Immune Resistance: How Cancer Protects from Immune Attack. Cancer Discov. 2015, 5, 915-919.
    • (2015) Cancer Discov , vol.5 , pp. 915-919
    • Ribas, A.1
  • 3
    • 0037421593 scopus 로고    scopus 로고
    • Fatal Melanoma Transferred in a Donated Kidney 16 Years after Melanoma Surgery
    • MacKie R. M., Reid R., Junor B., Fatal Melanoma Transferred in a Donated Kidney 16 Years after Melanoma Surgery. N. Engl. J. Med. 2003, 348, 567-568.
    • (2003) N. Engl. J. Med , vol.348 , pp. 567-568
    • MacKie, R.M.1    Reid, R.2    Junor, B.3
  • 4
    • 84884901379 scopus 로고    scopus 로고
    • Donor Cancer Transmission in Kidney Transplantation: A Systematic Review
    • Xiao D., Craig J. C., Chapman J. R., et al. Donor Cancer Transmission in Kidney Transplantation: A Systematic Review. Am. J. Transplant. 2013, 13, 2645-2652.
    • (2013) Am. J. Transplant , vol.13 , pp. 2645-2652
    • Xiao, D.1    Craig, J.C.2    Chapman, J.R.3
  • 5
    • 0018829492 scopus 로고
    • The in Vivo Distribution of Transferred Syngeneic, Allogeneic, and Xenogeneic Lymphoid Cells: Implication for the Adoptive Immunotherapy of Tumors
    • Mathisen D. J., Rosenberg S. A., The In Vivo Distribution of Transferred Syngeneic, Allogeneic, and Xenogeneic Lymphoid Cells: Implication for the Adoptive Immunotherapy of Tumors. J. Immunol. 1980, 124, 2295-2300.
    • (1980) J. Immunol , vol.124 , pp. 2295-2300
    • Mathisen, D.J.1    Rosenberg, S.A.2
  • 6
    • 0018971129 scopus 로고
    • In Vitro Growth of Murine T Cells: V. The Isolation and Growth of Lymphoid Cells Infiltrating Syngeneic Solid Tumors
    • Yron I., Wood T. A. Jr., Spiess P. J., et al. In Vitro Growth of Murine T Cells: V. The Isolation and Growth of Lymphoid Cells Infiltrating Syngeneic Solid Tumors. J. Immunol. 1980, 125, 238-245.
    • (1980) J. Immunol , vol.125 , pp. 238-245
    • Yron, I.1    Wood, T.A.2    Spiess, P.J.3
  • 7
    • 0028607185 scopus 로고
    • A Peptide Encoded by Human Gene MAGE-3 and Presented by HLA-A2 Induces Cytolytic T Lymphocytes That Recognize Tumor Cells Expressing MAGE-3
    • van der Bruggen P., Bastin J., Gajewski T., et al. A Peptide Encoded by Human Gene MAGE-3 and Presented by HLA-A2 Induces Cytolytic T Lymphocytes That Recognize Tumor Cells Expressing MAGE-3. Eur. J. Immuol. 1994, 24, 3038-3043.
    • (1994) Eur. J. Immuol , vol.24 , pp. 3038-3043
    • Van Der Bruggen, P.1    Bastin, J.2    Gajewski, T.3
  • 8
    • 0026322151 scopus 로고
    • A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
    • van der Bruggen P., Traversari C., Chomez P., et al. A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science 1991, 254, 1643-1647.
    • (1991) Science , vol.254 , pp. 1643-1647
    • Van Der Bruggen, P.1    Traversari, C.2    Chomez, P.3
  • 9
    • 0023099992 scopus 로고
    • Production of Stable Cytolytic T-Cell Clones Directed against Autologous Human Melanoma
    • Herin M., Lemoine C., Weynants P., et al. Production of Stable Cytolytic T-Cell Clones Directed against Autologous Human Melanoma. Int. J. Cancer 1987, 39, 390-396.
    • (1987) Int. J. Cancer , vol.39 , pp. 390-396
    • Herin, M.1    Lemoine, C.2    Weynants, P.3
  • 10
    • 0024166189 scopus 로고
    • Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma: A Preliminary Report
    • Rosenberg S. A., Packard B. S., Aebersold P. M., et al. Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma: A Preliminary Report. N. Engl. J. Med. 1988, 319, 1676-1680.
    • (1988) N. Engl. J. Med , vol.319 , pp. 1676-1680
    • Rosenberg, S.A.1    Packard, B.S.2    Aebersold, P.M.3
  • 11
    • 0024418334 scopus 로고
    • Presence on a Human Melanoma of Multiple Antigens Recognized by Autologous CTL
    • Van den Eynde B., Hainaut P., Herin M., et al. Presence on a Human Melanoma of Multiple Antigens Recognized by Autologous CTL. Int. J. Cancer 1989, 44, 634-640.
    • (1989) Int. J. Cancer , vol.44 , pp. 634-640
    • Van Den Eynde, B.1    Hainaut, P.2    Herin, M.3
  • 12
    • 0025155682 scopus 로고
    • Cellular Peptide Composition Governed by Major Histocompatibility Complex Class i Molecules
    • Falk K., Rotzschke O., Rammensee H. G., Cellular Peptide Composition Governed by Major Histocompatibility Complex Class I Molecules. Nature 1990, 348, 248-251.
    • (1990) Nature , vol.348 , pp. 248-251
    • Falk, K.1    Rotzschke, O.2    Rammensee, H.G.3
  • 13
    • 0025175893 scopus 로고
    • Isolation and Analysis of Naturally Processed Viral Peptides as Recognized by Cytotoxic T Cells
    • Rotzschke O., Falk K., Deres K., et al. Isolation and Analysis of Naturally Processed Viral Peptides as Recognized by Cytotoxic T Cells. Nature 1990, 348, 252-254.
    • (1990) Nature , vol.348 , pp. 252-254
    • Rotzschke, O.1    Falk, K.2    Deres, K.3
  • 14
    • 0024324442 scopus 로고
    • Association of Class i Major Histocompatibility Heavy and Light Chains Induced by Viral Peptides
    • Townsend A., Ohlen C., Bastin J., et al. Association of Class I Major Histocompatibility Heavy and Light Chains Induced by Viral Peptides. Nature 1989, 340, 443-448.
    • (1989) Nature , vol.340 , pp. 443-448
    • Townsend, A.1    Ohlen, C.2    Bastin, J.3
  • 15
    • 0025021304 scopus 로고
    • Identification of Classical Minor Histocompatibility Antigen as Cell-Derived Peptide
    • Wallny H. J., Rammensee H. G., Identification of Classical Minor Histocompatibility Antigen as Cell-Derived Peptide. Nature 1990, 343, 275-278.
    • (1990) Nature , vol.343 , pp. 275-278
    • Wallny, H.J.1    Rammensee, H.G.2
  • 16
    • 84862122547 scopus 로고    scopus 로고
    • The Role of Classical and Non-Classical HLA Class i Antigens in Human Tumors
    • Bukur J., Jasinski S., Seliger B., The Role of Classical and Non-Classical HLA Class I Antigens in Human Tumors. Semin. Cancer Biol. 2012, 22, 350-358.
    • (2012) Semin. Cancer Biol , vol.22 , pp. 350-358
    • Bukur, J.1    Jasinski, S.2    Seliger, B.3
  • 17
    • 84883157468 scopus 로고    scopus 로고
    • MHC Class i Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells
    • Leone P., Shin E. C., Perosa F., et al. MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells. J. Natl. Cancer Inst. 2013, 105, 1172-1187.
    • (2013) J. Natl. Cancer Inst , vol.105 , pp. 1172-1187
    • Leone, P.1    Shin, E.C.2    Perosa, F.3
  • 18
    • 52649163840 scopus 로고    scopus 로고
    • Prognostic Effect of Epithelial and Stromal Lymphocyte Infiltration in Non-Small Cell Lung Cancer
    • Al-Shibli K. I., Donnem T., Al-Saad S., et al. Prognostic Effect of Epithelial and Stromal Lymphocyte Infiltration in Non-Small Cell Lung Cancer. Clin. Cancer Res. 2008, 14, 5220-5227.
    • (2008) Clin. Cancer Res , vol.14 , pp. 5220-5227
    • Al-Shibli, K.I.1    Donnem, T.2    Al-Saad, S.3
  • 19
    • 84858800620 scopus 로고    scopus 로고
    • The Immune Contexture in Human Tumours: Impact on Clinical Outcome
    • Fridman W. H., Pages F., Sautes-Fridman C., et al. The Immune Contexture in Human Tumours: Impact on Clinical Outcome. Nat. Rev. Cancer 2012, 12, 298-306.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3
  • 20
    • 33749319703 scopus 로고    scopus 로고
    • Type, Density, and Location of Immune Cells within Human Colorectal Tumors Predict Clinical Outcome
    • Galon J., Costes A., Sanchez-Cabo F., et al. Type, Density, and Location of Immune Cells within Human Colorectal Tumors Predict Clinical Outcome. Science 2006, 313, 1960-1964.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 21
    • 84933181457 scopus 로고    scopus 로고
    • Role of Inflammatory Infiltrates in Triple Negative Breast Cancer
    • Matsumoto H., Koo S. L., Dent R., et al. Role of Inflammatory Infiltrates in Triple Negative Breast Cancer. J. Clin. Pathol. 2015, 68, 506-510.
    • (2015) J. Clin. Pathol , vol.68 , pp. 506-510
    • Matsumoto, H.1    Koo, S.L.2    Dent, R.3
  • 22
    • 84862557227 scopus 로고    scopus 로고
    • CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer
    • Nielsen J. S., Sahota R. A., Milne K., et al. CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer. Clin. Cancer Res. 2012, 18, 3281-3292.
    • (2012) Clin. Cancer Res , vol.18 , pp. 3281-3292
    • Nielsen, J.S.1    Sahota, R.A.2    Milne, K.3
  • 23
    • 29444442811 scopus 로고    scopus 로고
    • Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes and a High CD8+/Regulatory T Cell Ratio Are Associated with Favorable Prognosis in Ovarian Cancer
    • Sato E., Olson S. H., Ahn J., et al. Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes and a High CD8+/Regulatory T Cell Ratio Are Associated with Favorable Prognosis in Ovarian Cancer. Proc. Nat. Acad. Sci. U. S. A. 2005, 102, 18538-18543.
    • (2005) Proc. Nat. Acad. Sci. U. S. A , vol.102 , pp. 18538-18543
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 24
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
    • Zhang L., Conejo-Garcia J. R., Katsaros D., et al. Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer. N. Engl. J. Med. 2003, 348, 203-213.
    • (2003) N. Engl. J. Med , vol.348 , pp. 203-213
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3
  • 25
    • 84892959147 scopus 로고    scopus 로고
    • The Immune System and Response to HER2-Targeted Treatment in Breast Cancer
    • Bianchini G., Gianni L., The Immune System and Response to HER2-Targeted Treatment in Breast Cancer. Lancet Oncol. 2014, 15, e58-e68.
    • (2014) Lancet Oncol , vol.15 , pp. e58-e68
    • Bianchini, G.1    Gianni, L.2
  • 26
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-Associated Lymphocytes as an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer
    • Denkert C., Loibl S., Noske A., et al. Tumor-Associated Lymphocytes as an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer. J. Clin. Oncol. 2010, 28, 105-113.
    • (2010) J. Clin. Oncol , vol.28 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3
  • 27
    • 84964696930 scopus 로고    scopus 로고
    • Tumor-Infiltrating Immune Cell Profiles and Their Change after Neoadjuvant Chemotherapy Predict Response and Prognosis of Breast Cancer
    • Garcia-Martinez E., Gil G. L., Benito A. C., et al. Tumor-Infiltrating Immune Cell Profiles and Their Change after Neoadjuvant Chemotherapy Predict Response and Prognosis of Breast Cancer. Breast Cancer Res. 2014, 16, 488.
    • (2014) Breast Cancer Res , vol.16 , pp. 488
    • Garcia-Martinez, E.1    Gil, G.L.2    Benito, A.C.3
  • 28
    • 84878002092 scopus 로고    scopus 로고
    • Trial Watch: Dendritic Cell-Based Interventions for Cancer Therapy
    • Galluzzi L., Senovilla L., Vacchelli E., et al. Trial Watch: Dendritic Cell-Based Interventions for Cancer Therapy. Oncoimmunology 2012, 1, 1111-1134.
    • (2012) Oncoimmunology , vol.1 , pp. 1111-1134
    • Galluzzi, L.1    Senovilla, L.2    Vacchelli, E.3
  • 29
    • 84880721353 scopus 로고    scopus 로고
    • Dendritic-Cell-Based Therapeutic Cancer Vaccines
    • Palucka K., Banchereau J., Dendritic-Cell-Based Therapeutic Cancer Vaccines. Immunity 2013, 39, 38-48.
    • (2013) Immunity , vol.39 , pp. 38-48
    • Palucka, K.1    Banchereau, J.2
  • 30
    • 84885432340 scopus 로고    scopus 로고
    • Trial Watch: DNA Vaccines for Cancer Therapy
    • Senovilla L., Vacchelli E., Garcia P., et al. Trial Watch: DNA Vaccines for Cancer Therapy. Oncoimmunology 2013, 2, e23803.
    • (2013) Oncoimmunology , vol.2 , pp. e23803
    • Senovilla, L.1    Vacchelli, E.2    Garcia, P.3
  • 31
    • 84877940678 scopus 로고    scopus 로고
    • Trial Watch: Peptide Vaccines in Cancer Therapy
    • Vacchelli E., Martins I., Eggermont A., et al. Trial Watch: Peptide Vaccines in Cancer Therapy. Oncoimmunology 2012, 1, 1557-1576.
    • (2012) Oncoimmunology , vol.1 , pp. 1557-1576
    • Vacchelli, E.1    Martins, I.2    Eggermont, A.3
  • 32
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
    • Kantoff P. W., Higano C. S., Shore N. D., et al. Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer. N. Engl. J. Med. 2010, 363, 411-422.
    • (2010) N. Engl. J. Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 33
    • 84928062583 scopus 로고    scopus 로고
    • Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
    • Topalian S. L., Drake C. G., Pardoll D. M., Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy. Cancer Cell 2015, 27, 450-461.
    • (2015) Cancer Cell , vol.27 , pp. 450-461
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 34
    • 84871338258 scopus 로고    scopus 로고
    • Different Affinity Windows for Virus and Cancer-Specific T-Cell Receptors: Implications for Therapeutic Strategies
    • Aleksic M., Liddy N., Molloy P. E., et al. Different Affinity Windows for Virus and Cancer-Specific T-Cell Receptors: Implications for Therapeutic Strategies. Eur. J. Immunol. 2012, 42, 3174-3179.
    • (2012) Eur. J. Immunol , vol.42 , pp. 3174-3179
    • Aleksic, M.1    Liddy, N.2    Molloy, P.E.3
  • 35
    • 83055179941 scopus 로고    scopus 로고
    • Structural and Biophysical Determinants of Alphabeta T-Cell Antigen Recognition
    • Bridgeman J. S., Sewell A. K., Miles J. J., et al. Structural and Biophysical Determinants of Alphabeta T-Cell Antigen Recognition. Immunology 2011, 135, 9-18.
    • (2011) Immunology , vol.135 , pp. 9-18
    • Bridgeman, J.S.1    Sewell, A.K.2    Miles, J.J.3
  • 36
    • 34247605947 scopus 로고    scopus 로고
    • Human TCR-Binding Affinity Is Governed by MHC Class Restriction
    • Cole D. K., Pumphrey N. J., Boulter J. M., et al. Human TCR-Binding Affinity Is Governed by MHC Class Restriction. J. Immunol. 2007, 178, 5727-5734.
    • (2007) J. Immunol , vol.178 , pp. 5727-5734
    • Cole, D.K.1    Pumphrey, N.J.2    Boulter, J.M.3
  • 37
    • 78149432308 scopus 로고    scopus 로고
    • Immune Regulation of Cancer
    • Disis M. L., Immune Regulation of Cancer. J. Clin. Oncol. 2010, 28, 4531-4538.
    • (2010) J. Clin. Oncol , vol.28 , pp. 4531-4538
    • Disis, M.L.1
  • 38
    • 84928771999 scopus 로고    scopus 로고
    • T Cell Exclusion, Immune Privilege, and the Tumor Microenvironment
    • Joyce J. A., Fearon D. T., T Cell Exclusion, Immune Privilege, and the Tumor Microenvironment. Science 2015, 348, 74-80.
    • (2015) Science , vol.348 , pp. 74-80
    • Joyce, J.A.1    Fearon, D.T.2
  • 39
    • 77954801079 scopus 로고    scopus 로고
    • Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
    • Hodi F. S., O'Day S. J., McDermott D. F., et al. Improved Survival with Ipilimumab in Patients with Metastatic Melanoma. N. Engl. J. Med. 2010, 363, 711-723.
    • (2010) N. Engl. J. Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 40
    • 75249100054 scopus 로고    scopus 로고
    • Ipilimumab Monotherapy in Patients with Pretreated Advanced Melanoma: A Randomised, Double-Blind, Multicentre, Phase 2, Dose-Ranging Study
    • Wolchok J. D., Neyns B., Linette G., et al. Ipilimumab Monotherapy in Patients with Pretreated Advanced Melanoma: A Randomised, Double-Blind, Multicentre, Phase 2, Dose-Ranging Study. Lancet Oncol. 2010, 11, 155-164.
    • (2010) Lancet Oncol , vol.11 , pp. 155-164
    • Wolchok, J.D.1    Neyns, B.2    Linette, G.3
  • 41
    • 84862859820 scopus 로고    scopus 로고
    • Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
    • Topalian S. L., Hodi F. S., Brahmer J. R., et al. Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer. N. Engl. J. Med. 2012, 366, 2443-2454.
    • (2012) N. Engl. J. Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 42
    • 84938205998 scopus 로고    scopus 로고
    • Pembrolizumab versus Investigator-Choice Chemotherapy for Ipilimumab-Refractory Melanoma (KEYNOTE-002): A Randomised, Controlled, Phase 2 Trial
    • Ribas A., Puzanov I., Dummer R., et al. Pembrolizumab versus Investigator-Choice Chemotherapy for Ipilimumab-Refractory Melanoma (KEYNOTE-002): A Randomised, Controlled, Phase 2 Trial. Lancet Oncol. 2015, 16, 908-918.
    • (2015) Lancet Oncol , vol.16 , pp. 908-918
    • Ribas, A.1    Puzanov, I.2    Dummer, R.3
  • 43
    • 84929481480 scopus 로고    scopus 로고
    • Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer
    • Garon E. B., Rizvi N. A., Hui R., et al. Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer. N. Engl. J. Med. 2015, 372, 2018-2028.
    • (2015) N. Engl. J. Med , vol.372 , pp. 2018-2028
    • Garon, E.B.1    Rizvi, N.A.2    Hui, R.3
  • 44
    • 84862903106 scopus 로고    scopus 로고
    • Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
    • Brahmer J. R., Tykodi S. S., Chow L. Q., et al. Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer. N. Engl. J. Med. 2012, 366, 2455-2465.
    • (2012) N. Engl. J. Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 45
    • 84864052441 scopus 로고    scopus 로고
    • Management of Immune-Related Adverse Events and Kinetics of Response with Ipilimumab
    • Weber J. S., Kahler K. C., Hauschild A., Management of Immune-Related Adverse Events and Kinetics of Response with Ipilimumab. J. Clin. Oncol. 2012, 30, 2691-2697.
    • (2012) J. Clin. Oncol , vol.30 , pp. 2691-2697
    • Weber, J.S.1    Kahler, K.C.2    Hauschild, A.3
  • 46
    • 77951714425 scopus 로고    scopus 로고
    • Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-Term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients
    • Besser M. J., Shapira-Frommer R., Treves A. J., et al. Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-Term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients. Clin. Cancer Res. 2010, 16, 2646-2655.
    • (2010) Clin. Cancer Res , vol.16 , pp. 2646-2655
    • Besser, M.J.1    Shapira-Frommer, R.2    Treves, A.J.3
  • 47
    • 78650316191 scopus 로고    scopus 로고
    • CD8+ Enriched "young" Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma
    • Dudley M. E., Gross C. A., Langhan M. M., et al. CD8+ Enriched "Young" Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma. Clin. Cancer Res. 2010, 16, 6122-6131.
    • (2010) Clin. Cancer Res , vol.16 , pp. 6122-6131
    • Dudley, M.E.1    Gross, C.A.2    Langhan, M.M.3
  • 48
    • 84887991307 scopus 로고    scopus 로고
    • Randomized Selection Design Trial Evaluating CD8+-Enriched versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients with Melanoma
    • Dudley M. E., Gross C. A., Somerville R. P., et al. Randomized Selection Design Trial Evaluating CD8+-Enriched versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients with Melanoma. J. Clin. Oncol. 2013, 31, 2152-2159.
    • (2013) J. Clin. Oncol , vol.31 , pp. 2152-2159
    • Dudley, M.E.1    Gross, C.A.2    Somerville, R.P.3
  • 49
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive Cell Transfer Therapy following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients with Refractory Metastatic Melanoma
    • Dudley M. E., Wunderlich J. R., Yang J. C., et al. Adoptive Cell Transfer Therapy following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients with Refractory Metastatic Melanoma. J. Clin. Oncol. 2005, 23, 2346-2357.
    • (2005) J. Clin. Oncol , vol.23 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3
  • 50
    • 79960299888 scopus 로고    scopus 로고
    • Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
    • Rosenberg S. A., Yang J. C., Sherry R. M., et al. Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy. Clin. Cancer Res. 2011, 17, 4550-4557.
    • (2011) Clin. Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 51
    • 84903846565 scopus 로고    scopus 로고
    • Efficient Identification of Mutated Cancer Antigens Recognized by T Cells Associated with Durable Tumor Regressions
    • Lu Y. C., Yao X., Crystal J. S., et al. Efficient Identification of Mutated Cancer Antigens Recognized by T Cells Associated with Durable Tumor Regressions. Clin. Cancer Res. 2014, 20, 3401-3410.
    • (2014) Clin. Cancer Res , vol.20 , pp. 3401-3410
    • Lu, Y.C.1    Yao, X.2    Crystal, J.S.3
  • 52
    • 84928770388 scopus 로고    scopus 로고
    • Neoantigens in Cancer Immunotherapy
    • Schumacher T. N., Schreiber R. D., Neoantigens in Cancer Immunotherapy. Science 2015, 348, 69-74.
    • (2015) Science , vol.348 , pp. 69-74
    • Schumacher, T.N.1    Schreiber, R.D.2
  • 53
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of Somatic Mutation in Human Cancer Genomes
    • Greenman C., Stephens P., Smith R., et al. Patterns of Somatic Mutation in Human Cancer Genomes. Nature 2007, 446, 153-158.
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3
  • 54
    • 84883477049 scopus 로고    scopus 로고
    • BRAF/NRAS Wild-Type Melanomas Have a High Mutation Load Correlating with Histologic and Molecular Signatures of UV Damage
    • Mar V. J., Wong S. Q., Li J., et al. BRAF/NRAS Wild-Type Melanomas Have a High Mutation Load Correlating with Histologic and Molecular Signatures of UV Damage. Clin. Cancer Res. 2013, 19, 4589-4598.
    • (2013) Clin. Cancer Res , vol.19 , pp. 4589-4598
    • Mar, V.J.1    Wong, S.Q.2    Li, J.3
  • 55
    • 84893562519 scopus 로고    scopus 로고
    • Chimeric Antigen Receptor Therapy for Cancer
    • Barrett D. M., Singh N., Porter D. L., et al. Chimeric Antigen Receptor Therapy for Cancer. Annu. Rev. Med. 2014, 65, 333-347.
    • (2014) Annu. Rev. Med , vol.65 , pp. 333-347
    • Barrett, D.M.1    Singh, N.2    Porter, D.L.3
  • 56
    • 49649120397 scopus 로고    scopus 로고
    • Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody
    • Bargou R., Leo E., Zugmaier G., et al. Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody. Science 2008, 321, 974-977.
    • (2008) Science , vol.321 , pp. 974-977
    • Bargou, R.1    Leo, E.2    Zugmaier, G.3
  • 57
    • 84878931351 scopus 로고    scopus 로고
    • Targeting T Cells to Tumor Cells Using Bispecific Antibodies
    • Frankel S. R., Baeuerle P. A., Targeting T Cells to Tumor Cells Using Bispecific Antibodies. Curr. Opin. Chem. Biol. 2013, 17, 385-392.
    • (2013) Curr. Opin. Chem. Biol , vol.17 , pp. 385-392
    • Frankel, S.R.1    Baeuerle, P.A.2
  • 58
    • 83655196673 scopus 로고    scopus 로고
    • Novel Monoclonal Antibodies for Cancer Treatment: The Trifunctional Antibody Catumaxomab (Removab)
    • Seimetz D., Novel Monoclonal Antibodies for Cancer Treatment: The Trifunctional Antibody Catumaxomab (Removab). J. Cancer 2011, 2, 309-316.
    • (2011) J. Cancer , vol.2 , pp. 309-316
    • Seimetz, D.1
  • 59
    • 84907585592 scopus 로고    scopus 로고
    • T-Cell Receptor-Like Antibodies: Targeting the Intracellular Proteome Therapeutic Potential and Clinical Applications
    • Cohen M., Reiter Y., T-Cell Receptor-Like Antibodies: Targeting the Intracellular Proteome Therapeutic Potential and Clinical Applications. Antibodies 2013, 2, 517-534.
    • (2013) Antibodies , vol.2 , pp. 517-534
    • Cohen, M.1    Reiter, Y.2
  • 60
    • 84859068537 scopus 로고    scopus 로고
    • T-Cell-Receptor-Like Antibodies - Generation, Function and Applications
    • Dahan R., Reiter Y., T-Cell-Receptor-Like Antibodies-Generation, Function and Applications. Exp. Rev. Mol. Med. 2012, 14, e6.
    • (2012) Exp. Rev. Mol. Med , vol.14 , pp. e6
    • Dahan, R.1    Reiter, Y.2
  • 61
    • 84899965539 scopus 로고    scopus 로고
    • Examining the Presentation of Tumor Associated Antigens on Peptide-Pulsed T2 Cells
    • Bossi G., Gerry A. B., Paston S. J., et al. Examining the Presentation of Tumor Associated Antigens on Peptide-Pulsed T2 Cells. Oncoimmunology 2013, 2, e26840.
    • (2013) Oncoimmunology , vol.2 , pp. e26840
    • Bossi, G.1    Gerry, A.B.2    Paston, S.J.3
  • 62
    • 84862025335 scopus 로고    scopus 로고
    • Monoclonal TCR-Redirected Tumor Cell Killing
    • Liddy N., Bossi G., Adams K. J., et al. Monoclonal TCR-Redirected Tumor Cell Killing. Nat. Med. 2012, 18, 980-987.
    • (2012) Nat. Med , vol.18 , pp. 980-987
    • Liddy, N.1    Bossi, G.2    Adams, K.J.3
  • 63
    • 84877840760 scopus 로고    scopus 로고
    • Bi-Specific TCR-Anti CD3 Redirected T-Cell Targeting of NY-ESO-1- and LAGE-1-Positive Tumors
    • McCormack E., Adams K. J., Hassan N. J., et al. Bi-Specific TCR-Anti CD3 Redirected T-Cell Targeting of NY-ESO-1- and LAGE-1-Positive Tumors. Cancer Immunol. Immunother. 2013, 62, 773-785.
    • (2013) Cancer Immunol. Immunother , vol.62 , pp. 773-785
    • McCormack, E.1    Adams, K.J.2    Hassan, N.J.3
  • 64
    • 84886945598 scopus 로고    scopus 로고
    • ImmTACs: Novel Bi-Specific Agents for Targeted Cancer Therapy
    • Oates J., Jakobsen B. K., ImmTACs: Novel Bi-Specific Agents for Targeted Cancer Therapy. Oncoimmunology 2013, 2, e22891.
    • (2013) Oncoimmunology , vol.2 , pp. e22891
    • Oates, J.1    Jakobsen, B.K.2
  • 65
    • 84895758316 scopus 로고    scopus 로고
    • Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor
    • Pierce B. G., Hellman L. M., Hossain M., et al. Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor. PLoS Comput. Biol. 2014, 10, e1003478.
    • (2014) PLoS Comput. Biol , vol.10 , pp. e1003478
    • Pierce, B.G.1    Hellman, L.M.2    Hossain, M.3
  • 66
    • 84931265899 scopus 로고    scopus 로고
    • T Cell Receptor Engineering and Analysis Using the Yeast Display Platform
    • Smith S. N., Harris D. T., Kranz D. M., T Cell Receptor Engineering and Analysis Using the Yeast Display Platform. Methods Mol. Biol. 2015, 1319, 95-141.
    • (2015) Methods Mol. Biol , vol.1319 , pp. 95-141
    • Smith, S.N.1    Harris, D.T.2    Kranz, D.M.3
  • 67
    • 33645498495 scopus 로고    scopus 로고
    • Directed Evolution of Human T Cell Receptor CDR2 Residues by Phage Display Dramatically Enhances Affinity for Cognate Peptide-MHC without Increasing Apparent Cross-Reactivity
    • Dunn S. M., Rizkallah P. J., Baston E., et al. Directed Evolution of Human T Cell Receptor CDR2 Residues by Phage Display Dramatically Enhances Affinity for Cognate Peptide-MHC without Increasing Apparent Cross-Reactivity. Protein Sci. 2006, 15, 710-721.
    • (2006) Protein Sci , vol.15 , pp. 710-721
    • Dunn, S.M.1    Rizkallah, P.J.2    Baston, E.3
  • 68
    • 21444445173 scopus 로고    scopus 로고
    • Directed Evolution of Human T-Cell Receptors with Picomolar Affinities by Phage Display
    • Li Y., Moysey R., Molloy P. E., et al. Directed Evolution of Human T-Cell Receptors with Picomolar Affinities by Phage Display. Nat. Biotechnol. 2005, 23, 349-354.
    • (2005) Nat. Biotechnol , vol.23 , pp. 349-354
    • Li, Y.1    Moysey, R.2    Molloy, P.E.3
  • 69
    • 0142215405 scopus 로고    scopus 로고
    • Stable, Soluble T-Cell Receptor Molecules for Crystallization and Therapeutics
    • Boulter J. M., Glick M., Todorov P. T., et al. Stable, Soluble T-Cell Receptor Molecules for Crystallization and Therapeutics. Protein Eng. 2003, 16, 707-711.
    • (2003) Protein Eng , vol.16 , pp. 707-711
    • Boulter, J.M.1    Glick, M.2    Todorov, P.T.3
  • 70
    • 34447306898 scopus 로고    scopus 로고
    • The HLA A∗0201-Restricted hTERT(540-548) Peptide Is Not Detected on Tumor Cells by a CTL Clone or a High-Affinity T-Cell Receptor
    • Purbhoo M. A., Li Y., Sutton D. H., et al. The HLA A∗0201-Restricted hTERT(540-548) Peptide Is Not Detected on Tumor Cells by a CTL Clone or a High-Affinity T-Cell Receptor. Mol. Cancer Ther. 2007, 6, 2081-2091.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 2081-2091
    • Purbhoo, M.A.1    Li, Y.2    Sutton, D.H.3
  • 71
    • 33744938168 scopus 로고    scopus 로고
    • Quantifying and Imaging NY-ESO-1/LAGE-1-Derived Epitopes on Tumor Cells Using High Affinity T Cell Receptors
    • Purbhoo M. A., Sutton D. H., Brewer J. E., et al. Quantifying and Imaging NY-ESO-1/LAGE-1-Derived Epitopes on Tumor Cells Using High Affinity T Cell Receptors. J. Immunol. 2006, 176, 7308-7316.
    • (2006) J. Immunol , vol.176 , pp. 7308-7316
    • Purbhoo, M.A.1    Sutton, D.H.2    Brewer, J.E.3
  • 72
    • 34548782285 scopus 로고    scopus 로고
    • Crystal Structures of High Affinity Human T-Cell Receptors Bound to Peptide Major Histocompatibility Complex Reveal Native Diagonal Binding Geometry
    • Sami M., Rizkallah P. J., Dunn S., et al. Crystal Structures of High Affinity Human T-Cell Receptors Bound to Peptide Major Histocompatibility Complex Reveal Native Diagonal Binding Geometry. Protein Eng. Des. Sel. 2007, 20, 397-403.
    • (2007) Protein Eng. Des. Sel , vol.20 , pp. 397-403
    • Sami, M.1    Rizkallah, P.J.2    Dunn, S.3
  • 73
    • 84920265061 scopus 로고    scopus 로고
    • The Mayo Clinic Experience with the Use of Kinase Inhibitors, Ipilimumab, Bevacizumab, and Local Therapies in the Treatment of Metastatic Uveal Melanoma
    • Moser J. C., Pulido J. S., Dronca R. S., et al. The Mayo Clinic Experience with the Use of Kinase Inhibitors, Ipilimumab, Bevacizumab, and Local Therapies in the Treatment of Metastatic Uveal Melanoma. Melanoma Res. 2015, 25, 59-63.
    • (2015) Melanoma Res , vol.25 , pp. 59-63
    • Moser, J.C.1    Pulido, J.S.2    Dronca, R.S.3
  • 74
    • 70149114880 scopus 로고    scopus 로고
    • Gene Therapy with Human and Mouse T-Cell Receptors Mediates Cancer Regression and Targets Normal Tissues Expressing Cognate Antigen
    • Johnson L. A., Morgan R. A., Dudley M. E., et al. Gene Therapy with Human and Mouse T-Cell Receptors Mediates Cancer Regression and Targets Normal Tissues Expressing Cognate Antigen. Blood 2009, 114, 535-546.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3
  • 75
    • 84873991752 scopus 로고    scopus 로고
    • Cancer Regression and Neurological Toxicity following Anti-MAGE-A3 TCR Gene Therapy
    • Morgan R. A., Chinnasamy N., Abate-Daga D., et al. Cancer Regression and Neurological Toxicity following Anti-MAGE-A3 TCR Gene Therapy. J. Immunother. 2013, 36, 133-351.
    • (2013) J. Immunother , vol.36 , pp. 133-351
    • Morgan, R.A.1    Chinnasamy, N.2    Abate-Daga, D.3
  • 76
    • 79952304769 scopus 로고    scopus 로고
    • Tumor Regression in Patients with Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive with NY-ESO-1
    • Robbins P. F., Morgan R. A., Feldman S. A., et al. Tumor Regression in Patients with Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive with NY-ESO-1. J. Clin. Oncol. 2011, 29, 917-924.
    • (2011) J. Clin. Oncol , vol.29 , pp. 917-924
    • Robbins, P.F.1    Morgan, R.A.2    Feldman, S.A.3
  • 77
    • 84938963928 scopus 로고    scopus 로고
    • NY-ESO-1-Specific TCR-Engineered T Cells Mediate Sustained Antigen-Specific Antitumor Effects in Myeloma
    • Rapoport A. P., Stadtmauer E. A., Binder-Scholl G. K., et al. NY-ESO-1-Specific TCR-Engineered T Cells Mediate Sustained Antigen-Specific Antitumor Effects in Myeloma. Nat. Med. 2015, 21, 914-921.
    • (2015) Nat. Med , vol.21 , pp. 914-921
    • Rapoport, A.P.1    Stadtmauer, E.A.2    Binder-Scholl, G.K.3
  • 78
    • 38449104431 scopus 로고    scopus 로고
    • High-Affinity TCRs Generated by Phage Display Provide CD4+ T Cells with the Ability to Recognize and Kill Tumor Cell Lines
    • Zhao Y., Bennett A. D., Zheng Z., et al. High-Affinity TCRs Generated by Phage Display Provide CD4+ T Cells with the Ability to Recognize and Kill Tumor Cell Lines. J. Immunol. 2007, 179, 5845-5854.
    • (2007) J. Immunol , vol.179 , pp. 5845-5854
    • Zhao, Y.1    Bennett, A.D.2    Zheng, Z.3
  • 79
    • 58149280299 scopus 로고    scopus 로고
    • T-Cell Receptor Binding Affinities and Kinetics: Impact on T-Cell Activity and Specificity
    • Stone J. D., Chervin A. S., Kranz D. M., T-Cell Receptor Binding Affinities and Kinetics: Impact on T-Cell Activity and Specificity. Immunology 2009, 126, 165-176.
    • (2009) Immunology , vol.126 , pp. 165-176
    • Stone, J.D.1    Chervin, A.S.2    Kranz, D.M.3
  • 80
    • 84883705209 scopus 로고    scopus 로고
    • Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies
    • Stone J. D., Kranz D. M., Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies. Front. Immunol. 2013, 4, 244.
    • (2013) Front. Immunol , vol.4 , pp. 244
    • Stone, J.D.1    Kranz, D.M.2
  • 81
    • 0027320440 scopus 로고
    • Vaccination with Cytotoxic T Lymphocyte Epitope-Containing Peptide Protects against a Tumor Induced by Human Papillomavirus Type 16-Transformed Cells
    • Feltkamp M. C., Smits H. L., Vierboom M. P., et al. Vaccination with Cytotoxic T Lymphocyte Epitope-Containing Peptide Protects against a Tumor Induced by Human Papillomavirus Type 16-Transformed Cells. Eur. J. Immunol. 1993, 23, 2242-2249.
    • (1993) Eur. J. Immunol , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3
  • 82
    • 0026770269 scopus 로고
    • Induction of Cytotoxic T Lymphocytes with Peptides in Vitro: Identification of Candidate T-Cell Epitopes in Human Papilloma Virus
    • Stauss H. J., Davies H., Sadovnikova E., et al. Induction of Cytotoxic T Lymphocytes with Peptides In Vitro: Identification of Candidate T-Cell Epitopes in Human Papilloma Virus. Proc. Nat. Acad. Sci. U. S. A. 1992, 89, 7871-7875.
    • (1992) Proc. Nat. Acad. Sci. U. S. A , vol.89 , pp. 7871-7875
    • Stauss, H.J.1    Davies, H.2    Sadovnikova, E.3
  • 83
    • 0026518291 scopus 로고
    • T-Cell Immunity to the Joining Region of p210BCR-ABL Protein
    • Chen W., Peace D. J., Rovira D. K., et al. T-Cell Immunity to the Joining Region of p210BCR-ABL Protein. Proc. Nat. Acad. Sci. U. S. A. 1992, 89, 1468-1472.
    • (1992) Proc. Nat. Acad. Sci. U. S. A , vol.89 , pp. 1468-1472
    • Chen, W.1    Peace, D.J.2    Rovira, D.K.3
  • 84
    • 0018743916 scopus 로고
    • Detection of a Transformation-Related Antigen in Chemically Induced Sarcomas and Other Transformed Cells of the Mouse
    • DeLeo A. B., Jay G., Appella E., et al. Detection of a Transformation-Related Antigen in Chemically Induced Sarcomas and Other Transformed Cells of the Mouse. Proc. Nat. Acad. Sci. U. S. A. 1979, 76, 2420-2424.
    • (1979) Proc. Nat. Acad. Sci. U. S. A , vol.76 , pp. 2420-2424
    • DeLeo, A.B.1    Jay, G.2    Appella, E.3
  • 85
    • 0025882042 scopus 로고
    • T Cell Recognition of Transforming Proteins Encoded by Mutated Ras Proto-Oncogenes
    • Peace D. J., Chen W., Nelson H., et al. T Cell Recognition of Transforming Proteins Encoded by Mutated Ras Proto-Oncogenes. J. Immunol. 1991, 146, 2059-2065.
    • (1991) J. Immunol , vol.146 , pp. 2059-2065
    • Peace, D.J.1    Chen, W.2    Nelson, H.3
  • 86
    • 0027368821 scopus 로고
    • Induction of T Cells Specific for the Mutated Segment of Oncogenic P21ras Protein by Immunization in Vivo with the Oncogenic Protein
    • Peace D. J., Smith J. W., Disis M. L., et al. Induction of T Cells Specific for the Mutated Segment of Oncogenic P21ras Protein by Immunization In Vivo with the Oncogenic Protein. J. Immunother. Emphasis Tumor Immunol. 1993, 14, 110-114.
    • (1993) J. Immunother. Emphasis Tumor Immunol , vol.14 , pp. 110-114
    • Peace, D.J.1    Smith, J.W.2    Disis, M.L.3
  • 87
    • 0027405374 scopus 로고
    • Identification of Two Cytotoxic T Lymphocyte-Recognized Epitopes in the Ras Protein
    • Skipper J., Stauss H. J., Identification of Two Cytotoxic T Lymphocyte-Recognized Epitopes in the Ras Protein. J. Exp. Med. 1993, 177, 1493-1498.
    • (1993) J. Exp. Med , vol.177 , pp. 1493-1498
    • Skipper, J.1    Stauss, H.J.2
  • 88
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of Mutational Processes in Human Cancer
    • Alexandrov L. B., Nik-Zainal S., Wedge D. C., et al. Signatures of Mutational Processes in Human Cancer. Nature 2013, 500, 415-421.
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1    Nik-Zainal, S.2    Wedge, D.C.3
  • 89
    • 71049153709 scopus 로고    scopus 로고
    • Cancer/Testis (CT) Antigens: Potential Targets for Immunotherapy
    • Caballero O. L., Chen Y. T., Cancer/Testis (CT) Antigens: Potential Targets for Immunotherapy. Cancer Sci. 2009, 100, 2014-2021.
    • (2009) Cancer Sci , vol.100 , pp. 2014-2021
    • Caballero, O.L.1    Chen, Y.T.2
  • 90
    • 0032499710 scopus 로고    scopus 로고
    • Identification of Multiple Cancer/Testis Antigens by Allogeneic Antibody Screening of a Melanoma Cell Line Library
    • Chen Y. T., Gure A. O., Tsang S., et al. Identification of Multiple Cancer/Testis Antigens by Allogeneic Antibody Screening of a Melanoma Cell Line Library. Proc. Nat. Acad. Sci. U. S. A. 1998, 95, 6919-6923.
    • (1998) Proc. Nat. Acad. Sci. U. S. A , vol.95 , pp. 6919-6923
    • Chen, Y.T.1    Gure, A.O.2    Tsang, S.3
  • 91
    • 33646391659 scopus 로고    scopus 로고
    • Identification of a New Cancer/Germline Gene, KK-LC-1, Encoding an Antigen Recognized by Autologous CTL Induced on Human Lung Adenocarcinoma
    • Fukuyama T., Hanagiri T., Takenoyama M., et al. Identification of a New Cancer/Germline Gene, KK-LC-1, Encoding an Antigen Recognized by Autologous CTL Induced on Human Lung Adenocarcinoma. Cancer Res. 2006, 66, 4922-4928.
    • (2006) Cancer Res , vol.66 , pp. 4922-4928
    • Fukuyama, T.1    Hanagiri, T.2    Takenoyama, M.3
  • 92
    • 12344334809 scopus 로고    scopus 로고
    • Identification of the Gonad-Specific Anion Transporter SLCO6A1 as a Cancer/Testis (CT) Antigen Expressed in Human Lung Cancer
    • Lee S.-Y., Williamson B., Caballero O. L., et al. Identification of the Gonad-Specific Anion Transporter SLCO6A1 as a Cancer/Testis (CT) Antigen Expressed in Human Lung Cancer. Cancer Immun. 2004, 4, 13.
    • (2004) Cancer Immun , vol.4 , pp. 13
    • Lee, S.-Y.1    Williamson, B.2    Caballero, O.L.3
  • 93
    • 3342991899 scopus 로고    scopus 로고
    • A Novel Diffuse Large B-Cell Lymphoma-Associated Cancer Testis Antigen Encoding a PAS Domain Protein
    • Liggins A. P., Brown P. J., Asker K., et al. A Novel Diffuse Large B-Cell Lymphoma-Associated Cancer Testis Antigen Encoding a PAS Domain Protein. Br. J. Cancer 2004, 91, 141-149.
    • (2004) Br. J. Cancer , vol.91 , pp. 141-149
    • Liggins, A.P.1    Brown, P.J.2    Asker, K.3
  • 94
    • 13344282077 scopus 로고
    • Human Neoplasms Elicit Multiple Specific Immune Responses in the Autologous Host
    • Sahin U., Tureci O., Schmitt H., et al. Human Neoplasms Elicit Multiple Specific Immune Responses in the Autologous Host. Proc. Nat. Acad. Sci. U. S. A. 1995, 92, 11810-11813.
    • (1995) Proc. Nat. Acad. Sci. U. S. A , vol.92 , pp. 11810-11813
    • Sahin, U.1    Tureci, O.2    Schmitt, H.3
  • 95
    • 12644276375 scopus 로고    scopus 로고
    • A Testicular Antigen Aberrantly Expressed in Human Cancers Detected by Autologous Antibody Screening
    • Chen Y. T., Scanlan M. J., Sahin U., et al. A Testicular Antigen Aberrantly Expressed in Human Cancers Detected by Autologous Antibody Screening. Proc. Nat. Acad. Sci. U. S. A. 1997, 94, 1914-1918.
    • (1997) Proc. Nat. Acad. Sci. U. S. A , vol.94 , pp. 1914-1918
    • Chen, Y.T.1    Scanlan, M.J.2    Sahin, U.3
  • 97
    • 0035853136 scopus 로고    scopus 로고
    • Identification of Proacrosin Binding Protein sp32 Precursor as a Human Cancer/Testis Antigen
    • Ono T., Kurashige T., Harada N., et al. Identification of Proacrosin Binding Protein sp32 Precursor as a Human Cancer/Testis Antigen. Proc. Nat. Acad. Sci. U. S. A. 2001, 98, 3282-3287.
    • (2001) Proc. Nat. Acad. Sci. U. S. A , vol.98 , pp. 3282-3287
    • Ono, T.1    Kurashige, T.2    Harada, N.3
  • 98
    • 0037467672 scopus 로고    scopus 로고
    • Identification and Characterization of a Novel Cancer/Testis Antigen Gene CAGE-1
    • Park S., Lim Y., Lee D., et al. Identification and Characterization of a Novel Cancer/Testis Antigen Gene CAGE-1. Biochim. Biophys. Acta 2003, 1625, 173-182.
    • (2003) Biochim. Biophys. Acta , vol.1625 , pp. 173-182
    • Park, S.1    Lim, Y.2    Lee, D.3
  • 99
    • 1842398548 scopus 로고    scopus 로고
    • The SSX-2 Gene, Which Is Involved in the t (X; 18) Translocation of Synovial Sarcomas, Codes for the Human Tumor Antigen HOM-MEL-40
    • Türeci Ö., Sahin U., Schobert I., et al. The SSX-2 Gene, Which Is Involved in the t (X; 18) Translocation of Synovial Sarcomas, Codes for the Human Tumor Antigen HOM-MEL-40. Cancer Res. 1996, 56, 4766-4772.
    • (1996) Cancer Res , vol.56 , pp. 4766-4772
    • Türeci, Ö.1    Sahin, U.2    Schobert, I.3
  • 100
    • 0032574717 scopus 로고    scopus 로고
    • Identification of a Meiosis-Specific Protein as a Member of the Class of Cancer/Testis Antigens
    • Türeci Ö., Sahin U., Zwick C., et al. Identification of a Meiosis-Specific Protein as a Member of the Class of Cancer/Testis Antigens. Proc. Nat. Acad. Sci. U. S. A. 1998, 95, 5211-5216.
    • (1998) Proc. Nat. Acad. Sci. U. S. A , vol.95 , pp. 5211-5216
    • Türeci, Ö.1    Sahin, U.2    Zwick, C.3
  • 101
    • 0031848985 scopus 로고    scopus 로고
    • Major Histocompatibility Complex Expression on Human, Male Germ Cells: A Review
    • Fiszer D., Kurpisz M., Major Histocompatibility Complex Expression on Human, Male Germ Cells: A Review. Am. J. Reprod. Immunol. 1998, 40, 172-176.
    • (1998) Am. J. Reprod. Immunol , vol.40 , pp. 172-176
    • Fiszer, D.1    Kurpisz, M.2
  • 102
    • 84868617843 scopus 로고    scopus 로고
    • Meta-Analysis of Clinical Data Using Human Meiotic Genes Identifies a Novel Cohort of Highly Restricted Cancer-Specific Marker Genes
    • Feichtinger J., Aldeailej I., Anderson R., et al. Meta-Analysis of Clinical Data Using Human Meiotic Genes Identifies a Novel Cohort Of Highly Restricted Cancer-Specific Marker Genes. Oncotarget 2012, 3, 843-853.
    • (2012) Oncotarget , vol.3 , pp. 843-853
    • Feichtinger, J.1    Aldeailej, I.2    Anderson, R.3
  • 103
    • 25144503301 scopus 로고    scopus 로고
    • The Human Tumor Antigen PRAME Is a Dominant Repressor of Retinoic Acid Receptor Signaling
    • Epping M. T., Wang L., Edel M. J., et al. The Human Tumor Antigen PRAME Is a Dominant Repressor of Retinoic Acid Receptor Signaling. Cell 2005, 122, 835-847.
    • (2005) Cell , vol.122 , pp. 835-847
    • Epping, M.T.1    Wang, L.2    Edel, M.J.3
  • 104
    • 33746610114 scopus 로고    scopus 로고
    • MAGE-A Tumor Antigens Target p53 Transactivation Function through Histone Deacetylase Recruitment and Confer Resistance to Chemotherapeutic Agents
    • Monte M., Simonatto M., Peche L. Y., et al. MAGE-A Tumor Antigens Target p53 Transactivation Function through Histone Deacetylase Recruitment and Confer Resistance to Chemotherapeutic Agents. Proc. Nat. Acad. Sci. U. S. A. 2006, 103, 11160-11165.
    • (2006) Proc. Nat. Acad. Sci. U. S. A , vol.103 , pp. 11160-11165
    • Monte, M.1    Simonatto, M.2    Peche, L.Y.3
  • 105
    • 35449006644 scopus 로고    scopus 로고
    • MAGE-A, mMage-b, and MAGE-C Proteins form Complexes with KAP1 and Suppress p53-Dependent Apoptosis in MAGE-Positive Cell Lines
    • Yang B., O'Herrin S. M., Wu J., et al. MAGE-A, mMage-b, and MAGE-C Proteins form Complexes with KAP1 and Suppress p53-Dependent Apoptosis in MAGE-Positive Cell Lines. Cancer Res. 2007, 67, 9954-9962.
    • (2007) Cancer Res , vol.67 , pp. 9954-9962
    • Yang, B.1    O'Herrin, S.M.2    Wu, J.3
  • 106
    • 84895922331 scopus 로고    scopus 로고
    • Meta-Analysis of Expression of l (3) mbt Tumor-Associated Germline Genes Supports the Model That a Soma-to-Germline Transition Is a Hallmark of Human Cancers
    • Feichtinger J., Larcombe L., McFarlane R. J., Meta-Analysis of Expression of l (3) mbt Tumor-Associated Germline Genes Supports the Model That a Soma-to-Germline Transition Is a Hallmark of Human Cancers. Int. J. Cancer 2014, 134, 2359-2365.
    • (2014) Int. J. Cancer , vol.134 , pp. 2359-2365
    • Feichtinger, J.1    Larcombe, L.2    McFarlane, R.J.3
  • 107
    • 78650631610 scopus 로고    scopus 로고
    • Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila
    • Janic A., Mendizabal L., Llamazares S., et al. Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila. Science 2010, 330, 1824-1827.
    • (2010) Science , vol.330 , pp. 1824-1827
    • Janic, A.1    Mendizabal, L.2    Llamazares, S.3
  • 108
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma
    • Liyanage U. K., Moore T. T., Joo H.-G., et al. Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma. J. Immunol. 2002, 169, 2756-2761.
    • (2002) J. Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.-G.3
  • 109
    • 79957678130 scopus 로고    scopus 로고
    • Induced Malignant Genome Reprogramming in Somatic Cells by Testis-Specific Factors
    • Wang J., Emadali A., Le Bescont A., et al. Induced Malignant Genome Reprogramming in Somatic Cells by Testis-Specific Factors. Biochim. Biophys. Acta 2011, 1809, 221-225.
    • (2011) Biochim. Biophys. Acta , vol.1809 , pp. 221-225
    • Wang, J.1    Emadali, A.2    Le Bescont, A.3
  • 110
    • 84890563386 scopus 로고    scopus 로고
    • Sustaining Cancer through Addictive Ectopic Gene Activation
    • Wang J., Rousseaux S., Khochbin S., Sustaining Cancer through Addictive Ectopic Gene Activation. Curr. Opin. Oncol. 2014, 26, 73-77.
    • (2014) Curr. Opin. Oncol , vol.26 , pp. 73-77
    • Wang, J.1    Rousseaux, S.2    Khochbin, S.3
  • 111
    • 0029957792 scopus 로고    scopus 로고
    • The Activation of Human Gene MAGE-1 in Tumor Cells Is Correlated with Genome-Wide Demethylation
    • De Smet C., De Backer O., Faraoni I., et al. The Activation of Human Gene MAGE-1 in Tumor Cells Is Correlated with Genome-Wide Demethylation. Proc. Nat. Acad. Sci. U. S. A. 1996, 93, 7149-7153.
    • (1996) Proc. Nat. Acad. Sci. U. S. A , vol.93 , pp. 7149-7153
    • De Smet, C.1    De Backer, O.2    Faraoni, I.3
  • 112
    • 20144387855 scopus 로고    scopus 로고
    • Frequent DNA Hypomethylation of Human Juxtacentromeric BAGE Loci in Cancer
    • Grunau C., Sanchez C., Ehrlich M., et al. Frequent DNA Hypomethylation of Human Juxtacentromeric BAGE Loci in Cancer. Genes Chromosomes Cancer 2005, 43, 11-24.
    • (2005) Genes Chromosomes Cancer , vol.43 , pp. 11-24
    • Grunau, C.1    Sanchez, C.2    Ehrlich, M.3
  • 113
    • 0028328854 scopus 로고
    • Expression of the MAGE-1 Tumor Antigen Is Up-Regulated by the Demethylating Agent 5-Aza-2′-Deoxycytidine
    • Weber J., Salgaller M., Samid D., et al. Expression of the MAGE-1 Tumor Antigen Is Up-Regulated by the Demethylating Agent 5-Aza-2′-Deoxycytidine. Cancer Res. 1994, 54, 1766-1771.
    • (1994) Cancer Res , vol.54 , pp. 1766-1771
    • Weber, J.1    Salgaller, M.2    Samid, D.3
  • 114
    • 0003142849 scopus 로고    scopus 로고
    • Cancer/Testis (CT) Antigens - A New Link between Gametogenesis and Cancer
    • Old L. J., Cancer/Testis (CT) Antigens-A New Link between Gametogenesis and Cancer. Cancer Immun. 2001, 1, 1.
    • (2001) Cancer Immun , vol.1 , pp. 1
    • Old, L.J.1
  • 115
  • 116
    • 58149186474 scopus 로고    scopus 로고
    • CTdatabase: A Knowledge-Base of High-Throughput and Curated Data on Cancer-Testis Antigens
    • Almeida L. G., Sakabe N. J., deOliveira A. R., et al. CTdatabase: A Knowledge-Base of High-Throughput and Curated Data on Cancer-Testis Antigens. Nucleic Acids Res. 2009, 37, D816-D819.
    • (2009) Nucleic Acids Res , vol.37 , pp. D816-D819
    • Almeida, L.G.1    Sakabe, N.J.2    DeOliveira, A.R.3
  • 118
    • 0942288397 scopus 로고    scopus 로고
    • Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-Specific Genes Colocalized in Chromosomal Clusters
    • Gotter J., Brors B., Hergenhahn M., et al. Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-Specific Genes Colocalized in Chromosomal Clusters. J. Exp. Med. 2004, 199, 155-166.
    • (2004) J. Exp. Med , vol.199 , pp. 155-166
    • Gotter, J.1    Brors, B.2    Hergenhahn, M.3
  • 119
    • 84891887628 scopus 로고    scopus 로고
    • Cause and Consequence of Cancer/Testis Antigen Activation in Cancer
    • Whitehurst A. W., Cause and Consequence of Cancer/Testis Antigen Activation in Cancer. Annu. Rev. Pharmacol. Toxicol. 2014, 54, 251-272.
    • (2014) Annu. Rev. Pharmacol. Toxicol , vol.54 , pp. 251-272
    • Whitehurst, A.W.1
  • 120
    • 65649093663 scopus 로고    scopus 로고
    • Cancer/Testis Antigen CT45: Analysis of mRNA and Protein Expression in Human Cancer
    • Chen Y. T., Hsu M., Lee P., et al. Cancer/Testis Antigen CT45: Analysis of mRNA and Protein Expression in Human Cancer. Int. J. Cancer. 2009, 124, 2893-2898.
    • (2009) Int. J. Cancer , vol.124 , pp. 2893-2898
    • Chen, Y.T.1    Hsu, M.2    Lee, P.3
  • 122
    • 0033931860 scopus 로고    scopus 로고
    • Monoclonal Antibody MA454 Reveals a Heterogeneous Expression Pattern of MAGE-1 Antigen in Formalin-Fixed Paraffin Embedded Lung Tumours
    • Jungbluth A. A., Stockert E., Chen Y. T., et al. Monoclonal Antibody MA454 Reveals a Heterogeneous Expression Pattern of MAGE-1 Antigen in Formalin-Fixed Paraffin Embedded Lung Tumours. Br. J. Cancer 2000, 83, 493-497.
    • (2000) Br. J. Cancer , vol.83 , pp. 493-497
    • Jungbluth, A.A.1    Stockert, E.2    Chen, Y.T.3
  • 123
    • 10844289762 scopus 로고    scopus 로고
    • Intratumor Heterogeneity of Cancer/Testis Antigens Expression in Human Cutaneous Melanoma Is Methylation-Regulated and Functionally Reverted by 5-Aza-2′-Deoxycytidine
    • Sigalotti L., Fratta E., Coral S., et al. Intratumor Heterogeneity of Cancer/Testis Antigens Expression in Human Cutaneous Melanoma Is Methylation-Regulated and Functionally Reverted by 5-Aza-2′-Deoxycytidine. Cancer Res. 2004, 64, 9167-9171.
    • (2004) Cancer Res , vol.64 , pp. 9167-9171
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3
  • 124
    • 0029028642 scopus 로고
    • Identification of a Novel Peptide Derived from the Melanocyte-Specific gp100 Antigen as the Dominant Epitope Recognized by an HLA-A2. 1-Restricted Anti-Melanoma CTL Line
    • Barker A. B., Schreurs M. W., Tafazzul G., et al. Identification of a Novel Peptide Derived from the Melanocyte-Specific gp100 Antigen as the Dominant Epitope Recognized by an HLA-A2. 1-Restricted Anti-Melanoma CTL Line. Int. J. Cancer 1995, 62, 97-102.
    • (1995) Int. J. Cancer , vol.62 , pp. 97-102
    • Barker, A.B.1    Schreurs, M.W.2    Tafazzul, G.3
  • 125
    • 0027165558 scopus 로고
    • The Tyrosinase Gene Codes for an Antigen Recognized by Autologous Cytolytic T Lymphocytes on HLA-A2 Melanomas
    • Brichard V., Van Pel A., Wolfel T., et al. The Tyrosinase Gene Codes for an Antigen Recognized by Autologous Cytolytic T Lymphocytes on HLA-A2 Melanomas. J. Exp. Med. 1993, 178, 489-495.
    • (1993) J. Exp. Med , vol.178 , pp. 489-495
    • Brichard, V.1    Van Pel, A.2    Wolfel, T.3
  • 126
    • 0028303166 scopus 로고
    • A New Gene Coding for a Differentiation Antigen Recognized by Autologous Cytolytic T Lymphocytes on HLA-A2 Melanomas
    • Coulie P. G., Brichard V., Van Pel A., et al. A New Gene Coding for a Differentiation Antigen Recognized by Autologous Cytolytic T Lymphocytes on HLA-A2 Melanomas. J. Exp. Med. 1994, 180, 35-42.
    • (1994) J. Exp. Med , vol.180 , pp. 35-42
    • Coulie, P.G.1    Brichard, V.2    Van Pel, A.3
  • 127
    • 0028304337 scopus 로고
    • Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines
    • Cox A. L., Skipper J., Chen Y., et al. Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines. Science 1994, 264, 716-719.
    • (1994) Science , vol.264 , pp. 716-719
    • Cox, A.L.1    Skipper, J.2    Chen, Y.3
  • 128
    • 0028316911 scopus 로고
    • Cloning of the Gene Coding for a Shared Human Melanoma Antigen Recognized by Autologous T Cells Infiltrating into Tumor
    • Kawakami Y., Eliyahu S., Delgado C. H., et al. Cloning of the Gene Coding for a Shared Human Melanoma Antigen Recognized by Autologous T Cells Infiltrating into Tumor. Proc. Nat. Acad. Sci. U. S. A. 1994, 91, 3515-3519.
    • (1994) Proc. Nat. Acad. Sci. U. S. A , vol.91 , pp. 3515-3519
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3
  • 129
    • 0028298174 scopus 로고
    • Identification of a Human Melanoma Antigen Recognized by Tumor-Infiltrating Lymphocytes Associated with in Vivo Tumor Rejection
    • Kawakami Y., Eliyahu S., Delgado C. H., et al. Identification of a Human Melanoma Antigen Recognized by Tumor-Infiltrating Lymphocytes Associated with In Vivo Tumor Rejection. Proc. Nat. Acad. Sci. U. S. A. 1994, 91, 6458-6462.
    • (1994) Proc. Nat. Acad. Sci. U. S. A , vol.91 , pp. 6458-6462
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3
  • 130
    • 0028302028 scopus 로고
    • Identification of the Immunodominant Peptides of the MART-1 Human Melanoma Antigen Recognized by the Majority of HLA-A2-Restricted Tumor Infiltrating Lymphocytes
    • Kawakami Y., Eliyahu S., Sakaguchi K., et al. Identification of the Immunodominant Peptides of the MART-1 Human Melanoma Antigen Recognized by the Majority of HLA-A2-Restricted Tumor Infiltrating Lymphocytes. J. Exp. Med. 1994, 180, 347-352.
    • (1994) J. Exp. Med , vol.180 , pp. 347-352
    • Kawakami, Y.1    Eliyahu, S.2    Sakaguchi, K.3
  • 131
    • 0028347940 scopus 로고
    • Two Tyrosinase Nonapeptides Recognized on HLA-A2 Melanomas by Autologous Cytolytic T Lymphocytes
    • Wolfel T., Van Pel A., Brichard V., et al. Two Tyrosinase Nonapeptides Recognized on HLA-A2 Melanomas by Autologous Cytolytic T Lymphocytes. Eur. J. Immunol. 1994, 24, 759-764.
    • (1994) Eur. J. Immunol , vol.24 , pp. 759-764
    • Wolfel, T.1    Van Pel, A.2    Brichard, V.3
  • 132
    • 84894559188 scopus 로고    scopus 로고
    • Tumour Antigens Recognized by T Lymphocytes: At the Core of Cancer Immunotherapy
    • Coulie P. G., Van den Eynde B. J., van der Bruggen P., et al. Tumour Antigens Recognized by T Lymphocytes: At the Core of Cancer Immunotherapy. Nat. Rev. Cancer 2014, 14, 135-146.
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 135-146
    • Coulie, P.G.1    Van Den Eynde, B.J.2    Van Der Bruggen, P.3
  • 133
    • 84857401848 scopus 로고    scopus 로고
    • Active Specific Immunotherapy Targeting the Wilms' Tumor Protein 1 (WT1) for Patients with Hematological Malignancies and Solid Tumors: Lessons from Early Clinical Trials
    • Van Driessche A., Berneman Z. N., Van Tendeloo V. F., Active Specific Immunotherapy Targeting the Wilms' Tumor Protein 1 (WT1) for Patients with Hematological Malignancies and Solid Tumors: Lessons from Early Clinical Trials. Oncologist 2012, 17, 250-259.
    • (2012) Oncologist , vol.17 , pp. 250-259
    • Van Driessche, A.1    Berneman, Z.N.2    Van Tendeloo, V.F.3
  • 134
    • 84929429616 scopus 로고    scopus 로고
    • Aurora Kinase A in Gastrointestinal Cancers: Time to Target
    • Katsha A., Belkhiri A., Goff L., et al. Aurora Kinase A in Gastrointestinal Cancers: Time to Target. Mol. Cancer 2015, 14, 106.
    • (2015) Mol. Cancer , vol.14 , pp. 106
    • Katsha, A.1    Belkhiri, A.2    Goff, L.3
  • 135
    • 84947224577 scopus 로고    scopus 로고
    • PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis
    • Kumar S., Kim J., PLK-1 Targeted Inhibitors and Their Potential against Tumorigenesis. BioMed Res. Int. 2015, 2015, 705745.
    • (2015) BioMed Res. Int , vol.2015 , pp. 705745
    • Kumar, S.1    Kim, J.2
  • 136
    • 84958957172 scopus 로고    scopus 로고
    • Development of Cell-Cycle Checkpoint Therapy for Solid Tumors
    • Tamura K., Development of Cell-Cycle Checkpoint Therapy for Solid Tumors. Jpn. J. Clin. Oncol. 2015, 45, 1097-1102.
    • (2015) Jpn. J. Clin. Oncol , vol.45 , pp. 1097-1102
    • Tamura, K.1
  • 138
    • 84884683734 scopus 로고    scopus 로고
    • MHC Class I-Associated Phosphopeptides Are the Targets of Memory-Like Immunity in Leukemia
    • Cobbold M., De La Pena H., Norris A., et al. MHC Class I-Associated Phosphopeptides Are the Targets of Memory-Like Immunity in Leukemia. Sci. Trans. Med. 2013, 5, 203ra125.
    • (2013) Sci. Trans. Med , vol.5 , pp. 203ra125
    • Cobbold, M.1    De La Pena, H.2    Norris, A.3
  • 139
    • 79961091168 scopus 로고    scopus 로고
    • An Antigenic Peptide Produced by Reverse Splicing and Double Asparagine Deamidation
    • Dalet A., Robbins P. F., Stroobant V., et al. An Antigenic Peptide Produced by Reverse Splicing and Double Asparagine Deamidation. Proc. Nat. Acad. Sci. U. S. A. 2011, 108, E323-E331.
    • (2011) Proc. Nat. Acad. Sci. U. S. A , vol.108 , pp. E323-E331
    • Dalet, A.1    Robbins, P.F.2    Stroobant, V.3
  • 140
    • 0001433072 scopus 로고    scopus 로고
    • An HLA-A2-restricted Tyrosinase Antigen on Melanoma Cells Results from Posttranslational Modification and Suggests a Novel Pathway for Processing of Membrane Proteins
    • Skipper J. C., Hendrickson R. C., Gulden P. H., et al. An HLA-A2-restricted Tyrosinase Antigen on Melanoma Cells Results from Posttranslational Modification and Suggests a Novel Pathway for Processing of Membrane Proteins. J. Exp. Med. 1996, 183, 527-534.
    • (1996) J. Exp. Med , vol.183 , pp. 527-534
    • Skipper, J.C.1    Hendrickson, R.C.2    Gulden, P.H.3
  • 141
    • 84917708479 scopus 로고    scopus 로고
    • MHC-Restricted Phosphopeptides from Insulin Receptor Substrate-2 and CDC25b Offer Broad-Based Immuno-therapeutic Agents for Cancer
    • Zarling A. L., Obeng R. C., Desch A. N., et al. MHC-Restricted Phosphopeptides from Insulin Receptor Substrate-2 and CDC25b Offer Broad-Based Immuno-therapeutic Agents for Cancer. Cancer Res. 2014, 74, 6784-6795.
    • (2014) Cancer Res , vol.74 , pp. 6784-6795
    • Zarling, A.L.1    Obeng, R.C.2    Desch, A.N.3
  • 142
    • 33749513200 scopus 로고    scopus 로고
    • Identification of Class i MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy
    • Zarling A. L., Polefrone J. M., Evans A. M., et al. Identification of Class I MHC-Associated Phosphopeptides as Targets for Cancer Immunotherapy. Proc. Nat. Acad. Sci. U. S. A. 2006, 103, 14889-14894.
    • (2006) Proc. Nat. Acad. Sci. U. S. A , vol.103 , pp. 14889-14894
    • Zarling, A.L.1    Polefrone, J.M.2    Evans, A.M.3
  • 143
    • 69049089548 scopus 로고    scopus 로고
    • The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
    • Cheever M. A., Allison J. P., Ferris A. S., et al. The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research. Clin. Cancer Res. 2009, 15, 5323-5337.
    • (2009) Clin. Cancer Res , vol.15 , pp. 5323-5337
    • Cheever, M.A.1    Allison, J.P.2    Ferris, A.S.3
  • 144
    • 77950475517 scopus 로고    scopus 로고
    • Case Report of a Serious Adverse Event following the Administration of T Cells Transduced with a Chimeric Antigen Receptor Recognizing ERBB2
    • Morgan R. A., Yang J. C., Kitano M., et al. Case Report of a Serious Adverse Event following the Administration of T Cells Transduced with a Chimeric Antigen Receptor Recognizing ERBB2. Mol. Ther. 2010, 18, 843-851.
    • (2010) Mol. Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3
  • 145
    • 79952187823 scopus 로고    scopus 로고
    • T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
    • Parkhurst M. R., Yang J. C., Langan R. C., et al. T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis. Mol. Ther. 2011, 19, 620-626.
    • (2011) Mol. Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3
  • 146
    • 84904471500 scopus 로고    scopus 로고
    • A Novel Cohort of Cancer-Testis Biomarker Genes Revealed through Meta-Analysis of Clinical Data Sets
    • Sammut S. J., Feichtinger J., Stuart N., et al. A Novel Cohort of Cancer-Testis Biomarker Genes Revealed through Meta-Analysis of Clinical Data Sets. Oncoscience 2014, 1, 349-359.
    • (2014) Oncoscience , vol.1 , pp. 349-359
    • Sammut, S.J.1    Feichtinger, J.2    Stuart, N.3
  • 147
    • 84924352568 scopus 로고    scopus 로고
    • Mapping the HLA Ligandome Landscape of Acute Myeloid Leukemia: A Targeted Approach toward Peptide-Based Immunotherapy
    • Berlin C., Kowalewski D. J., Schuster H., et al. Mapping the HLA Ligandome Landscape of Acute Myeloid Leukemia: A Targeted Approach toward Peptide-Based Immunotherapy. Leukemia 2015, 29, 647-659.
    • (2015) Leukemia , vol.29 , pp. 647-659
    • Berlin, C.1    Kowalewski, D.J.2    Schuster, H.3
  • 148
    • 84886075487 scopus 로고    scopus 로고
    • HLA Ligandome Tumor Antigen Discovery for Personalized Vaccine Approach
    • Rammensee H. G., Singh-Jasuja H., HLA Ligandome Tumor Antigen Discovery for Personalized Vaccine Approach. Expert Rev. Vaccines 2013, 12, 1211-1217.
    • (2013) Expert Rev. Vaccines , vol.12 , pp. 1211-1217
    • Rammensee, H.G.1    Singh-Jasuja, H.2
  • 149
    • 0033388725 scopus 로고    scopus 로고
    • SYFPEITHI: Database for MHC Ligands and Peptide Motifs
    • Rammensee H., Bachmann J., Emmerich N. P., et al. SYFPEITHI: Database for MHC Ligands and Peptide Motifs. Immunogenetics 1999, 50, 213-219.
    • (1999) Immunogenetics , vol.50 , pp. 213-219
    • Rammensee, H.1    Bachmann, J.2    Emmerich, N.P.3
  • 150
    • 0028052724 scopus 로고
    • Scheme for Ranking Potential HLA-A2 Binding Peptides Based on Independent Binding of Individual Peptide Side-Chains
    • Parker K. C., Bednarek M. A., Coligan J. E., Scheme for Ranking Potential HLA-A2 Binding Peptides Based on Independent Binding of Individual Peptide Side-Chains. J. Immunol. 1994, 152, 163-175.
    • (1994) J. Immunol , vol.152 , pp. 163-175
    • Parker, K.C.1    Bednarek, M.A.2    Coligan, J.E.3
  • 151
    • 84990011361 scopus 로고    scopus 로고
    • HLA-Binding Properties of Tumor Neoepitopes in Humans
    • Fritsch E. F., Rajasagi M., Ott P. A., et al. HLA-Binding Properties of Tumor Neoepitopes in Humans. Cancer Immunol. Res. 2014, 2, 522-529.
    • (2014) Cancer Immunol. Res , vol.2 , pp. 522-529
    • Fritsch, E.F.1    Rajasagi, M.2    Ott, P.A.3
  • 152
    • 2642555664 scopus 로고    scopus 로고
    • MAPPP: MHC Class i Antigenic Peptide Processing Prediction
    • Hakenberg J., Nussbaum A. K., Schild H., et al. MAPPP: MHC Class I Antigenic Peptide Processing Prediction. Appl. Bioinformatics 2003, 2, 155-158.
    • (2003) Appl. Bioinformatics , vol.2 , pp. 155-158
    • Hakenberg, J.1    Nussbaum, A.K.2    Schild, H.3
  • 153
    • 84927511820 scopus 로고    scopus 로고
    • The Immunoproteasome and Viral Infection: A Complex Regulator of Inflammation
    • McCarthy M. K., Weinberg J. B., The Immunoproteasome and Viral Infection: A Complex Regulator of Inflammation. Front. Microbiol. 2015, 6, 21.
    • (2015) Front. Microbiol , vol.6 , pp. 21
    • McCarthy, M.K.1    Weinberg, J.B.2
  • 154
    • 84867418338 scopus 로고    scopus 로고
    • A Structural Voyage toward an Understanding of the MHC-I-Restricted Immune Response: Lessons Learned and Much to Be Learned
    • Gras S., Burrows S. R., Turner S. J., et al. A Structural Voyage toward an Understanding of the MHC-I-Restricted Immune Response: Lessons Learned and Much to Be Learned. Immunol. Rev. 2012, 250, 61-81.
    • (2012) Immunol. Rev , vol.250 , pp. 61-81
    • Gras, S.1    Burrows, S.R.2    Turner, S.J.3
  • 156
    • 84900851981 scopus 로고    scopus 로고
    • Antigen Cross-Presentation of Immune Complexes
    • Platzer B., Stout M., Fiebiger E., Antigen Cross-Presentation of Immune Complexes. Front. Immunol. 2014, 5, 140.
    • (2014) Front. Immunol , vol.5 , pp. 140
    • Platzer, B.1    Stout, M.2    Fiebiger, E.3
  • 157
    • 0034606349 scopus 로고    scopus 로고
    • Cross-Priming of Naive CD8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells
    • Berard F., Blanco P., Davoust J., et al. Cross-Priming of Naive CD8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells. J. Exp. Med. 2000, 192, 1535-1544.
    • (2000) J. Exp. Med , vol.192 , pp. 1535-1544
    • Berard, F.1    Blanco, P.2    Davoust, J.3
  • 158
    • 84894514010 scopus 로고    scopus 로고
    • Characteristics of Tertiary Lymphoid Structures in Primary Cancers
    • Goc J., Fridman W. H., Sautes-Fridman C., et al. Characteristics of Tertiary Lymphoid Structures in Primary Cancers. Oncoimmunology 2013, 2, e26836.
    • (2013) Oncoimmunology , vol.2 , pp. e26836
    • Goc, J.1    Fridman, W.H.2    Sautes-Fridman, C.3
  • 159
    • 2342485077 scopus 로고    scopus 로고
    • Bystander Elimination of Antigen Loss Variants in Established Tumors
    • Spiotto M. T., Rowley D. A., Schreiber H., Bystander Elimination of Antigen Loss Variants in Established Tumors. Nat. Med. 2004, 10, 294-298.
    • (2004) Nat. Med , vol.10 , pp. 294-298
    • Spiotto, M.T.1    Rowley, D.A.2    Schreiber, H.3
  • 160
    • 2542616960 scopus 로고    scopus 로고
    • Antigen Bias in T Cell Cross-Priming
    • Wolkers M. C., Brouwenstijn N., Bakker A. H., et al. Antigen Bias in T Cell Cross-Priming. Science 2004, 304, 1314-1317.
    • (2004) Science , vol.304 , pp. 1314-1317
    • Wolkers, M.C.1    Brouwenstijn, N.2    Bakker, A.H.3
  • 161
    • 84899933079 scopus 로고    scopus 로고
    • ImmTAC-Redirected Tumour Cell Killing Induces and Potentiates Antigen Cross-Presentation by Dendritic Cells
    • Bossi G., Buisson S., Oates J., et al. ImmTAC-Redirected Tumour Cell Killing Induces and Potentiates Antigen Cross-Presentation by Dendritic Cells. Cancer Immunol. Immunother. 2014, 63, 437-448.
    • (2014) Cancer Immunol. Immunother , vol.63 , pp. 437-448
    • Bossi, G.1    Buisson, S.2    Oates, J.3
  • 162
    • 84860718270 scopus 로고    scopus 로고
    • Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells
    • Scholler J., Brady T. L., Binder-Scholl G., et al. Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells. Science Trans. Med. 2012, 4, 132ra53.
    • (2012) Science Trans. Med , vol.4 , pp. 132ra53
    • Scholler, J.1    Brady, T.L.2    Binder-Scholl, G.3
  • 163
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular Toxicity and Titin Cross-Reactivity of Affinity-Enhanced T Cells in Myeloma and Melanoma
    • Linette G. P., Stadtmauer E. A., Maus M. V., et al. Cardiovascular Toxicity and Titin Cross-Reactivity of Affinity-Enhanced T Cells in Myeloma and Melanoma. Blood 2013, 122, 863-871.
    • (2013) Blood , vol.122 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3
  • 164
    • 84883866836 scopus 로고    scopus 로고
    • Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells
    • Cameron B. J., Gerry A. B., Dukes J., et al. Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells. Science Trans. Med. 2013, 5, 197ra103.
    • (2013) Science Trans. Med , vol.5 , pp. 197ra103
    • Cameron, B.J.1    Gerry, A.B.2    Dukes, J.3
  • 165
    • 84929821227 scopus 로고    scopus 로고
    • ImmTacs for Targeted Cancer Therapy: Why, What, How, and Which
    • Oates J., Hassan N. J., Jakobsen B. K., ImmTacs for Targeted Cancer Therapy: Why, What, How, and Which. Mol. Immunol. 2015, 67, 67-74.
    • (2015) Mol. Immunol , vol.67 , pp. 67-74
    • Oates, J.1    Hassan, N.J.2    Jakobsen, B.K.3
  • 166
    • 84964282524 scopus 로고    scopus 로고
    • Cancer Stem Cells: The Promise and the Potential
    • Ajani J. A., Song S., Hochster H. S., et al. Cancer Stem Cells: The Promise and the Potential. Semin. Oncol. 2015, 42, S3-17.
    • (2015) Semin. Oncol , vol.42 , pp. S3-17
    • Ajani, J.A.1    Song, S.2    Hochster, H.S.3
  • 167
    • 84864880991 scopus 로고    scopus 로고
    • Full-Length mRNA-Seq from Single-Cell Levels of RNA and Individual Circulating Tumor Cells
    • Ramskold D., Luo S., Wang Y. C., et al. Full-Length mRNA-Seq from Single-Cell Levels of RNA and Individual Circulating Tumor Cells. Nat. Biotech. 2012, 30, 777-782.
    • (2012) Nat. Biotech , vol.30 , pp. 777-782
    • Ramskold, D.1    Luo, S.2    Wang, Y.C.3
  • 168
    • 84860601923 scopus 로고    scopus 로고
    • Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines
    • Powell A. A., Talasaz A. H., Zhang H., et al. Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines. PLoS One 2012, 7, e33788.
    • (2012) PLoS One , vol.7 , pp. e33788
    • Powell, A.A.1    Talasaz, A.H.2    Zhang, H.3
  • 169
    • 0037174674 scopus 로고    scopus 로고
    • Cancer Regression and Autoimmunity in Patients after Clonal Repopulation with Antitumor Lymphocytes
    • Dudley M. E., Wunderlich J. R., Robbins P. F., et al. Cancer Regression and Autoimmunity in Patients after Clonal Repopulation with Antitumor Lymphocytes. Science 2002, 298, 850-854.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3
  • 170
    • 33749624177 scopus 로고    scopus 로고
    • Cancer Regression in Patients after Transfer of Genetically Engineered Lymphocytes
    • Morgan R. A., Dudley M. E., Wunderlich J. R., et al. Cancer Regression in Patients after Transfer of Genetically Engineered Lymphocytes. Science 2006, 314, 126-129.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 171
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric Antigen Receptor-Modified T Cells for Acute Lymphoid Leukemia
    • Grupp S. A., Kalos M., Barrett D., et al. Chimeric Antigen Receptor-Modified T Cells for Acute Lymphoid Leukemia. N. Engl. J. Med. 2013, 368, 1509-1518.
    • (2013) N. Engl. J. Med , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3
  • 172
    • 80051775476 scopus 로고    scopus 로고
    • T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
    • Kalos M., Levine B. L., Porter D. L., et al. T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia. Sci. Trans. Med. 2011, 3, 95ra73-95ra73.
    • (2011) Sci. Trans. Med , vol.3 , pp. 95ra73-95ra73
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3
  • 173
    • 10344261422 scopus 로고    scopus 로고
    • Cutting Edge: Persistence of Transferred Lymphocyte Clonotypes Correlates with Cancer Regression in Patients Receiving Cell Transfer Therapy
    • Robbins P. F., Dudley M. E., Wunderlich J., et al. Cutting Edge: Persistence of Transferred Lymphocyte Clonotypes Correlates with Cancer Regression in Patients Receiving Cell Transfer Therapy. J. Immunol. 2004, 173, 7125-7130.
    • (2004) J. Immunol , vol.173 , pp. 7125-7130
    • Robbins, P.F.1    Dudley, M.E.2    Wunderlich, J.3
  • 174
    • 78751689288 scopus 로고    scopus 로고
    • Human Effector CD8+ T Cells Derived from Naive Rather Than Memory Subsets Possess Superior Traits for Adoptive Immunotherapy
    • Hinrichs C. S., Borman Z. A., Gattinoni L., et al. Human Effector CD8+ T Cells Derived from Naive Rather Than Memory Subsets Possess Superior Traits for Adoptive Immunotherapy. Blood 2011, 117, 808-814.
    • (2011) Blood , vol.117 , pp. 808-814
    • Hinrichs, C.S.1    Borman, Z.A.2    Gattinoni, L.3
  • 175
    • 11144241310 scopus 로고    scopus 로고
    • Transition of Late-Stage Effector T Cells to CD27+ CD28+ Tumor-Reactive Effector Memory T Cells in Humans after Adoptive Cell Transfer Therapy
    • Powell D. J. Jr., Dudley M. E., Robbins P. F., et al. Transition of Late-Stage Effector T Cells to CD27+ CD28+ Tumor-Reactive Effector Memory T Cells in Humans after Adoptive Cell Transfer Therapy. Blood 2005, 105, 241-250.
    • (2005) Blood , vol.105 , pp. 241-250
    • Powell, D.J.1    Dudley, M.E.2    Robbins, P.F.3
  • 176
    • 59849100381 scopus 로고    scopus 로고
    • Minimally Cultured Tumor-Infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy
    • Tran K. Q., Zhou J., Durflinger K. H., et al. Minimally Cultured Tumor-Infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy. J. Immunother. 2008, 31, 742-751.
    • (2008) J. Immunother , vol.31 , pp. 742-751
    • Tran, K.Q.1    Zhou, J.2    Durflinger, K.H.3
  • 177
    • 63849289233 scopus 로고    scopus 로고
    • High Avidity Myeloid Leukemia-Associated Antigen-Specific CD8+ T Cells Preferentially Reside in the Bone Marrow
    • Melenhorst J. J., Scheinberg P., Chattopadhyay P. K., et al. High Avidity Myeloid Leukemia-Associated Antigen-Specific CD8+ T Cells Preferentially Reside in the Bone Marrow. Blood 2009, 113, 2238-2244.
    • (2009) Blood , vol.113 , pp. 2238-2244
    • Melenhorst, J.J.1    Scheinberg, P.2    Chattopadhyay, P.K.3
  • 178
    • 84933277410 scopus 로고    scopus 로고
    • Spatial Genomic Heterogeneity within Localized, Multifocal Prostate Cancer
    • Boutros P. C., Fraser M., Harding N. J., et al. Spatial Genomic Heterogeneity within Localized, Multifocal Prostate Cancer. Nat. Genet. 2015, 47, 736-745.
    • (2015) Nat. Genet , vol.47 , pp. 736-745
    • Boutros, P.C.1    Fraser, M.2    Harding, N.J.3
  • 179
    • 84856013431 scopus 로고    scopus 로고
    • Clonal Evolution in Cancer
    • Greaves M., Maley C. C., Clonal Evolution in Cancer. Nature 2012, 481, 306-313.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2


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