An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins

Journal of Experimental Medicine

Volumn 183, Issue 2, 1996, Pages 527-534

  Skipper, Jonathan C A ^a   Hendrickson, Ronald C ^a   Gulden, Pamela H ^a   Brichard, Vincent ^c   Van Pel, Ailene ^c   Chen, Ye ^a   Shabanowitz, Jeffrey ^a   Wolfel, Thomas ^d   Slingluff Jr , Craig L ^b   Boon, Thierry ^c   Hunt, Donald F ^b   Engelhard, Victor H ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A2 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; MONOPHENOL MONOOXYGENASE;

ANTIGEN DETECTION; ANTIGEN RECOGNITION; ARTICLE; ENDOPLASMIC RETICULUM; HLA SYSTEM; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MELANOMA CELL; MOLECULAR CLONING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; ASPARAGINE; ASPARTIC ACID; CLONE CELLS; EPITOPES; HLA-A2 ANTIGEN; HUMANS; MELANOMA; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR CELLS, CULTURED;

EID: 0001433072     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.2.527     Document Type: Article

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