Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion

Neurobiology of Aging

Volumn 35, Issue 7, 2014, Pages 1779.e5-1779.e13

  Waite, Adrian J ^a   Bäumer, Dirk ^b   East, Simon ^b   Neal, James ^a   Morris, Huw R ^c   Ansorge, Olaf ^b   Blake, Derek J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis; C9orf72; Frontotemporal dementia; Frontotemporal lobar degeneration; Repeat expansion; Southern blotting

Indexed keywords

BRAIN PROTEIN; PROTEIN C9ORF72; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN LEVEL; C9ORF72 GENE; CEREBELLUM; COMPARATIVE STUDY; CONTROLLED STUDY; DNA PROBE; EXON; FRONTAL CORTEX; FRONTOTEMPORAL DEMENTIA; GENE AMPLIFICATION; GENETIC TRANSCRIPTION; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HEXANUCLEOTIDE REPEAT EXPANSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SOUTHERN BLOTTING;

AMYOTROPHIC LATERAL SCLEROSIS; C9ORF72; FRONTOTEMPORAL DEMENTIA; FRONTOTEMPORAL LOBAR DEGENERATION; REPEAT EXPANSION; SOUTHERN BLOTTING;

AMYOTROPHIC LATERAL SCLEROSIS; COHORT STUDIES; DNA REPEAT EXPANSION; FRONTAL LOBE; FRONTOTEMPORAL LOBAR DEGENERATION; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOTYPE; HUMANS; PHENOTYPE; PROTEINS;

EID: 85056706559     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.01.016     Document Type: Article

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