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Volumn 100, Issue 10, 2016, Pages 2024-2038

Establishing Biomarkers in Transplant Medicine: A Critical Review of Current Approaches

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA 1 MICROGLOBULIN; ANTIBODY; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CD163 ANTIGEN; CD72 ANTIGEN; CXCL9 CHEMOKINE; CYSTATIN C; DONOR SPECIFIC ANTIBODY; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN 7; INTERLEUKIN 18; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; SOMATOMEDIN BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84980409673     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000001321     Document Type: Review
Times cited : (72)

References (138)
  • 1
    • 84958231740 scopus 로고    scopus 로고
    • Moving beyondminimization trials in kidney transplantation
    • Matas AJ, Gaston RS.Moving beyondminimization trials in kidney transplantation. J Am Soc Nephrol. 2015;26:2898-2901.
    • (2015) J Am Soc Nephrol. , vol.26 , pp. 2898-2901
    • Matas, A.J.1    Gaston, R.S.2
  • 2
    • 79961051172 scopus 로고    scopus 로고
    • Surveillance protocol kidney transplant biopsies: Their evolving role in clinical practice
    • Henderson LK, Nankivell BJ, Chapman JR. Surveillance protocol kidney transplant biopsies: their evolving role in clinical practice. Am J Transplant. 2011;11:1570-1575.
    • (2011) Am J Transplant , vol.11 , pp. 1570-1575
    • Henderson, L.K.1    Nankivell, B.J.2    Chapman, J.R.3
  • 3
    • 84947967890 scopus 로고    scopus 로고
    • Zero-Time Renal Transplant Biopsies: A Comprehensive Review
    • Naesens M. Zero-Time Renal Transplant Biopsies: A Comprehensive Review. Transplantation. 2016;100:1425-1439.
    • (2016) Transplantation , vol.100 , pp. 1425-1439
    • Naesens, M.1
  • 4
    • 85008959098 scopus 로고    scopus 로고
    • The molecular phenotypes of rejection in kidney transplant biopsies
    • Halloran PF, Famulski K, Reeve J. The molecular phenotypes of rejection in kidney transplant biopsies. Curr Opin Organ Transplant. 2015;20:359-367.
    • (2015) Curr Opin Organ Transplant , vol.20 , pp. 359-367
    • Halloran, P.F.1    Famulski, K.2    Reeve, J.3
  • 5
    • 84895906520 scopus 로고    scopus 로고
    • Antibody-mediated rejection, T cell-mediated rejection, and the injury-repair response: New insights from the Genome Canada studies of kidney transplant biopsies
    • Halloran PF, Reeve JP, Pereira AB, et al. Antibody-mediated rejection, T cell-mediated rejection, and the injury-repair response: new insights from the Genome Canada studies of kidney transplant biopsies. Kidney Int. 2014;85:258-264.
    • (2014) Kidney Int , vol.85 , pp. 258-264
    • Halloran, P.F.1    Reeve, J.P.2    Pereira, A.B.3
  • 6
    • 84938796702 scopus 로고    scopus 로고
    • Transplant biopsy beyond light microscopy
    • Adam B, Mengel M. Transplant biopsy beyond light microscopy. BMC Nephrol. 2015;16:132.
    • (2015) BMC Nephrol , vol.16 , pp. 132
    • Adam, B.1    Mengel, M.2
  • 7
    • 0036314948 scopus 로고    scopus 로고
    • Post-transplant renal function in the first year predicts long-term kidney transplant survival
    • Hariharan S, McBride MA, Cherikh WS, et al. Post-transplant renal function in the first year predicts long-term kidney transplant survival. Kidney Int. 2002;62:311-318.
    • (2002) Kidney Int , vol.62 , pp. 311-318
    • Hariharan, S.1    McBride, M.A.2    Cherikh, W.S.3
  • 8
    • 84944108631 scopus 로고    scopus 로고
    • Urinary C-X-C motif chemokine 10 independently improves the noninvasive diagnosis of antibodymediated kidney allograft rejection
    • Rabant M, Amrouche L, Lebreton X, et al. Urinary C-X-C motif chemokine 10 independently improves the noninvasive diagnosis of antibodymediated kidney allograft rejection. J Am Soc Nephrol. 2015;26: 2840-2851.
    • (2015) J Am Soc Nephrol , vol.26 , pp. 2840-2851
    • Rabant, M.1    Amrouche, L.2    Lebreton, X.3
  • 9
    • 84897108187 scopus 로고    scopus 로고
    • Biomarkers for kidney transplant rejection
    • Lo DJ, Kaplan B, Kirk AD. Biomarkers for kidney transplant rejection. Nat Rev Nephrol. 2014;10:215-225.
    • (2014) Nat Rev Nephrol , vol.10 , pp. 215-225
    • Lo, D.J.1    Kaplan, B.2    Kirk, A.D.3
  • 10
    • 76949097789 scopus 로고    scopus 로고
    • Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients
    • Heilman RL, Devarapalli Y, Chakkera HA, et al. Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients. Am J Transplant. 2010;10:563-570.
    • (2010) Am J Transplant , vol.10 , pp. 563-570
    • Heilman, R.L.1    Devarapalli, Y.2    Chakkera, H.A.3
  • 11
    • 84860473178 scopus 로고    scopus 로고
    • Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant
    • Wiebe C, Gibson IW, Blydt-Hansen TD, et al. Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant. Am J Transplant. 2012;12:1157-1167.
    • (2012) Am J Transplant , vol.12 , pp. 1157-1167
    • Wiebe, C.1    Gibson, I.W.2    Blydt-Hansen, T.D.3
  • 12
    • 33846243266 scopus 로고    scopus 로고
    • Infiltrates in protocol biopsies from renal allografts
    • Mengel M, Gwinner W, Schwarz A, et al. Infiltrates in protocol biopsies from renal allografts. Am J Transplant. 2007;7:356-365.
    • (2007) Am J Transplant , vol.7 , pp. 356-365
    • Mengel, M.1    Gwinner, W.2    Schwarz, A.3
  • 13
    • 80054712257 scopus 로고    scopus 로고
    • Diagnosis and prevention of chronic kidney allograft loss
    • Nankivell BJ, Kuypers DR. Diagnosis and prevention of chronic kidney allograft loss. Lancet. 2011;378:1428-1437.
    • (2011) Lancet , vol.378 , pp. 1428-1437
    • Nankivell, B.J.1    Kuypers, D.R.2
  • 14
    • 74949094555 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for the care of kidney transplant recipients
    • Kidney Disease: Improving Global Outcomes (KDIGO) Transplant Work Group
    • Kidney Disease: Improving Global Outcomes (KDIGO) Transplant Work Group. KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant. 2009;(9 Suppl 3):S1-S155.
    • (2009) Am J Transplant , vol.9 , pp. S1-S155
  • 15
    • 84876996330 scopus 로고    scopus 로고
    • Transplantation: Proteinuria in kidney transplantation: An ongoing story
    • Legendre C, Anglicheau D. Transplantation: proteinuria in kidney transplantation: an ongoing story. Nat Rev Nephrol. 2013;9:251-252.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 251-252
    • Legendre, C.1    Anglicheau, D.2
  • 16
    • 84943142294 scopus 로고    scopus 로고
    • Evaluation and management of proteinuria after kidney transplantation
    • Tsampalieros A, Knoll GA. Evaluation and management of proteinuria after kidney transplantation. Transplantation. 2015;99:2049-2060.
    • (2015) Transplantation , vol.99 , pp. 2049-2060
    • Tsampalieros, A.1    Knoll, G.A.2
  • 17
    • 35748938216 scopus 로고    scopus 로고
    • Proteinuria after kidney transplantation, relationship to allograft histology and survival
    • Amer H, Fidler ME, Myslak M, et al. Proteinuria after kidney transplantation, relationship to allograft histology and survival. Am J Transplant. 2007;7:2748-2756.
    • (2007) Am J Transplant , vol.7 , pp. 2748-2756
    • Amer, H.1    Fidler, M.E.2    Myslak, M.3
  • 18
    • 76649135820 scopus 로고    scopus 로고
    • The clinical significance of early proteinuria after renal transplantation
    • Cherukuri A, Welberry-Smith MP, Tattersall JE, et al. The clinical significance of early proteinuria after renal transplantation. Transplantation. 2010;89:200-207.
    • (2010) Transplantation , vol.89 , pp. 200-207
    • Cherukuri, A.1    Welberry-Smith, M.P.2    Tattersall, J.E.3
  • 19
    • 33847711876 scopus 로고    scopus 로고
    • Urinary albumin excretion and the risk of graft loss and death in proteinuric and non-proteinuric renal transplant recipients
    • Halimi JM, Buchler M, Al-Najjar A, et al. Urinary albumin excretion and the risk of graft loss and death in proteinuric and non-proteinuric renal transplant recipients. Am J Transplant. 2007;7:618-625.
    • (2007) Am J Transplant , vol.7 , pp. 618-625
    • Halimi, J.M.1    Buchler, M.2    Al-Najjar, A.3
  • 20
    • 84874415147 scopus 로고    scopus 로고
    • Urine high and low molecular weight proteins one-year post-kidney transplant: Relationship to histology and graft survival
    • Amer H, Lieske JC, Rule AD, et al. Urine high and low molecular weight proteins one-year post-kidney transplant: relationship to histology and graft survival. Am J Transplant. 2013;13:676-684.
    • (2013) Am J Transplant , vol.13 , pp. 676-684
    • Amer, H.1    Lieske, J.C.2    Rule, A.D.3
  • 21
    • 84954426351 scopus 로고    scopus 로고
    • Proteinuria as a noninvasive marker for renal allograft histology and failure: An observational cohort study
    • Naesens M, Lerut E, Emonds MP, et al. Proteinuria as a noninvasive marker for renal allograft histology and failure: an observational cohort study. J Am Soc Nephrol. 2016;27:281-292.
    • (2016) J Am Soc Nephrol , vol.27 , pp. 281-292
    • Naesens, M.1    Lerut, E.2    Emonds, M.P.3
  • 22
    • 77955607610 scopus 로고    scopus 로고
    • Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation
    • Lefaucheur C, Loupy A, Hill GS, et al. Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation. J Am Soc Nephrol. 2010;21:1398-1406.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1398-1406
    • Lefaucheur, C.1    Loupy, A.2    Hill, G.S.3
  • 23
    • 84939564869 scopus 로고    scopus 로고
    • Assessing antibody strength: Comparison of MFI, C1q, and titer information
    • Tambur AR, Herrera ND, Haarberg KM, et al. Assessing antibody strength: comparison of MFI, C1q, and titer information. Am J Transplant. 2015;15:2421-2430.
    • (2015) Am J Transplant , vol.15 , pp. 2421-2430
    • Tambur, A.R.1    Herrera, N.D.2    Haarberg, K.M.3
  • 24
    • 77957606216 scopus 로고    scopus 로고
    • Molecular diagnostics in transplantation
    • Naesens M, Sarwal MM. Molecular diagnostics in transplantation. Nat Rev Nephrol. 2010;6:614-628.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 614-628
    • Naesens, M.1    Sarwal, M.M.2
  • 25
    • 49249087744 scopus 로고    scopus 로고
    • Noninvasive prediction of organ graft rejection and outcome using gene expression patterns
    • Anglicheau D, Suthanthiran M. Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. Transplantation. 2008;86:192-199.
    • (2008) Transplantation , vol.86 , pp. 192-199
    • Anglicheau, D.1    Suthanthiran, M.2
  • 26
    • 79956352550 scopus 로고    scopus 로고
    • Advances of genomic science and systems biology in renal transplantation: A review
    • Perkins D, Verma M, Park KJ. Advances of genomic science and systems biology in renal transplantation: a review. Semin Immunopathol. 2011;33:211-218.
    • (2011) Semin Immunopathol , vol.33 , pp. 211-218
    • Perkins, D.1    Verma, M.2    Park, K.J.3
  • 27
    • 84927595587 scopus 로고    scopus 로고
    • Molecular monitoring of alloimmune-mediated injury in kidney transplant patients
    • Traitanon O, Poggio ED, Fairchild RL. Molecular monitoring of alloimmune-mediated injury in kidney transplant patients. Curr Opin Nephrol Hypertens. 2014;23:625-630.
    • (2014) Curr Opin Nephrol Hypertens , vol.23 , pp. 625-630
    • Traitanon, O.1    Poggio, E.D.2    Fairchild, R.L.3
  • 28
    • 22844438322 scopus 로고    scopus 로고
    • Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients
    • Augustine JJ, Siu DS, Clemente MJ, et al. Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients. Am J Transplant. 2005;5: 1971-1975.
    • (2005) Am J Transplant , vol.5 , pp. 1971-1975
    • Augustine, J.J.1    Siu, D.S.2    Clemente, M.J.3
  • 29
    • 84888640668 scopus 로고    scopus 로고
    • Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation
    • Bestard O, Cruzado JM, Lucia M, et al. Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation. Kidney Int. 2013;84:1226-1236.
    • (2013) Kidney Int , vol.84 , pp. 1226-1236
    • Bestard, O.1    Cruzado, J.M.2    Lucia, M.3
  • 31
    • 68849088180 scopus 로고    scopus 로고
    • Diagnostic value of T-cell monitoring assays in kidney transplantation
    • Nickel P, Bestard O, Volk HD, et al. Diagnostic value of T-cell monitoring assays in kidney transplantation. Curr Opin Organ Transplant. 2009;14: 426-431.
    • (2009) Curr Opin Organ Transplant , vol.14 , pp. 426-431
    • Nickel, P.1    Bestard, O.2    Volk, H.D.3
  • 32
    • 84948695640 scopus 로고    scopus 로고
    • Interferon gamma ELISPOT testing as a risk-stratifying biomarker for kidney transplant injury: Results from the CTOT-01 multicenter study
    • Hricik DE, Augustine J, Nickerson P, et al. Interferon gamma ELISPOT testing as a risk-stratifying biomarker for kidney transplant injury: results from the CTOT-01 multicenter study. Am J Transplant. 2015;15: 3166-3173.
    • (2015) Am J Transplant , vol.15 , pp. 3166-3173
    • Hricik, D.E.1    Augustine, J.2    Nickerson, P.3
  • 33
    • 84863416747 scopus 로고    scopus 로고
    • Can immune cell function assay identify patients at risk of infection or rejection A meta-analysis
    • Ling X, Xiong J, Liang W, et al. Can immune cell function assay identify patients at risk of infection or rejection A meta-analysis. Transplantation. 2012;93:737-743.
    • (2012) Transplantation , vol.93 , pp. 737-743
    • Ling, X.1    Xiong, J.2    Liang, W.3
  • 34
    • 84951568204 scopus 로고    scopus 로고
    • Peripheral natural killer cell and allo-stimulated T-cell function in kidney transplant recipients associate with cancer risk and immunosuppression-related complications
    • Hope CM, Troelnikov A, Hanf W, et al. Peripheral natural killer cell and allo-stimulated T-cell function in kidney transplant recipients associate with cancer risk and immunosuppression-related complications. Kidney Int. 2015;88:1374-1382.
    • (2015) Kidney Int , vol.88 , pp. 1374-1382
    • Hope, C.M.1    Troelnikov, A.2    Hanf, W.3
  • 35
    • 40849097609 scopus 로고    scopus 로고
    • Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function
    • Aquino-Dias EC, Joelsons G, da Silva DM, et al. Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function. Kidney Int. 2008;73:877-884.
    • (2008) Kidney Int , vol.73 , pp. 877-884
    • Aquino-Dias, E.C.1    Joelsons, G.2    Da Silva, D.M.3
  • 36
    • 73249144602 scopus 로고    scopus 로고
    • Functional genomic analysis of peripheral blood during early acute renal allograft rejection
    • GuntherOP, Balshaw RF, Scherer A, et al. Functional genomic analysis of peripheral blood during early acute renal allograft rejection. Transplantation. 2009;88:942-951.
    • (2009) Transplantation , vol.88 , pp. 942-951
    • Gunther, O.P.1    Balshaw, R.F.2    Scherer, A.3
  • 37
    • 67650564908 scopus 로고    scopus 로고
    • Biomarkers for early and late stage chronic allograft nephropathy by proteogenomic profiling of peripheral blood
    • Kurian SM, Heilman R, Mondala TS, et al. Biomarkers for early and late stage chronic allograft nephropathy by proteogenomic profiling of peripheral blood. PLoS One. 2009;4:e6212.
    • (2009) PLoS One , vol.4 , pp. e6212
    • Kurian, S.M.1    Heilman, R.2    Mondala, T.S.3
  • 38
    • 38749116228 scopus 로고    scopus 로고
    • Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples
    • Li L, Ying L, Naesens M, et al. Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples. Physiol Genomics. 2008;32:190-197.
    • (2008) Physiol Genomics , vol.32 , pp. 190-197
    • Li, L.1    Ying, L.2    Naesens, M.3
  • 39
    • 84961933003 scopus 로고    scopus 로고
    • Identification of T cell-mediated vascular rejection after kidney transplantation by the combined measurement of 5 specific MicroRNAs in blood
    • Matz M, Fabritius K, Lorkowski C, et al. Identification of T cell-mediated vascular rejection after kidney transplantation by the combined measurement of 5 specific MicroRNAs in blood. Transplantation. 2016;100: 898-907.
    • (2016) Transplantation , vol.100 , pp. 898-907
    • Matz, M.1    Fabritius, K.2    Lorkowski, C.3
  • 40
    • 84938769719 scopus 로고    scopus 로고
    • A type i interferon signature characterizes chronic antibody-mediated rejection in kidney transplantation
    • Rascio F, Pontrelli P, Accetturo M, et al. A type I interferon signature characterizes chronic antibody-mediated rejection in kidney transplantation. J Pathol. 2015;237:72-84.
    • (2015) J Pathol , vol.237 , pp. 72-84
    • Rascio, F.1    Pontrelli, P.2    Accetturo, M.3
  • 41
    • 0042362188 scopus 로고    scopus 로고
    • Serial peripheral blood perforin and granzyme B gene expression measurements for prediction of acute rejection in kidney graft recipients
    • Simon T, Opelz G, Wiesel M, et al. Serial peripheral blood perforin and granzyme B gene expression measurements for prediction of acute rejection in kidney graft recipients. Am J Transplant. 2003;3:1121-1127.
    • (2003) Am J Transplant , vol.3 , pp. 1121-1127
    • Simon, T.1    Opelz, G.2    Wiesel, M.3
  • 42
    • 84899012442 scopus 로고    scopus 로고
    • Molecular classifiers for acute kidney transplant rejection in peripheral blood by whole genome gene expression profiling
    • Kurian SM, Williams AN, Gelbart T, et al. Molecular classifiers for acute kidney transplant rejection in peripheral blood by whole genome gene expression profiling. Am J Transplant. 2014;14:1164-1172.
    • (2014) Am J Transplant , vol.14 , pp. 1164-1172
    • Kurian, S.M.1    Williams, A.N.2    Gelbart, T.3
  • 43
    • 84922379541 scopus 로고    scopus 로고
    • The kSORT assay to detect renal transplant patients at high risk for acute rejection: Results of the multicenter AART study
    • Roedder S, Sigdel T, Salomonis N, et al. The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study. PLoS Med. 2014;11:e1001759.
    • (2014) PLoS Med , vol.11 , pp. e1001759
    • Roedder, S.1    Sigdel, T.2    Salomonis, N.3
  • 44
    • 84867093105 scopus 로고    scopus 로고
    • A peripheral blood diagnostic test for acute rejection in renal transplantation
    • Li L, Khatri P, Sigdel TK, et al. A peripheral blood diagnostic test for acute rejection in renal transplantation. Am J Transplant. 2012;12: 2710-2718.
    • (2012) Am J Transplant , vol.12 , pp. 2710-2718
    • Li, L.1    Khatri, P.2    Sigdel, T.K.3
  • 45
    • 41849131031 scopus 로고    scopus 로고
    • Immunosuppressive drug-free operational immune tolerance in human kidney transplant recipients: Part i Blood gene expression statistical analysis
    • Braud C, Baeten D, Giral M, et al. Immunosuppressive drug-free operational immune tolerance in human kidney transplant recipients: Part I. Blood gene expression statistical analysis. J Cell Biochem. 2008;103: 1681-1692.
    • (2008) J Cell Biochem , vol.103 , pp. 1681-1692
    • Braud, C.1    Baeten, D.2    Giral, M.3
  • 46
    • 34848857054 scopus 로고    scopus 로고
    • Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance
    • Brouard S, Mansfield E, Braud C, et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A. 2007;104:15448-15453.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15448-15453
    • Brouard, S.1    Mansfield, E.2    Braud, C.3
  • 47
    • 80052265345 scopus 로고    scopus 로고
    • Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients
    • Lozano JJ, Pallier A,Martinez-LlordellaM, et al. Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients. Am J Transplant. 2011;11:1916-1926.
    • (2011) Am J Transplant , vol.11 , pp. 1916-1926
    • Lozano, J.J.1    Pallier, A.2    Martinez-Llordella, M.3
  • 48
    • 77953178765 scopus 로고    scopus 로고
    • Identification of a B cell signature associated with renal transplant tolerance in humans
    • Newell KA, Asare A, Kirk AD, et al. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest. 2010; 120:1836-1847.
    • (2010) J Clin Invest , vol.120 , pp. 1836-1847
    • Newell, K.A.1    Asare, A.2    Kirk, A.D.3
  • 49
    • 77953209236 scopus 로고    scopus 로고
    • Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans
    • Sagoo P, Perucha E, Sawitzki B, et al. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.JClin Invest. 2010;120:1848-1861.
    • (2010) JClin Invest , vol.120 , pp. 1848-1861
    • Sagoo, P.1    Perucha, E.2    Sawitzki, B.3
  • 50
    • 84947018044 scopus 로고    scopus 로고
    • Reconsidering the detection of tolerance to individualize immunosuppression minimization and to improve longterm kidney graft outcomes
    • Baron D, Giral M, Brouard S. Reconsidering the detection of tolerance to individualize immunosuppression minimization and to improve longterm kidney graft outcomes. Transpl Int. 2015;28:938-959.
    • (2015) Transpl Int , vol.28 , pp. 938-959
    • Baron, D.1    Giral, M.2    Brouard, S.3
  • 51
    • 84929132806 scopus 로고    scopus 로고
    • A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft
    • Baron D, Ramstein G, Chesneau M, et al. A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft. Kidney Int. 2015;87:984-995.
    • (2015) Kidney Int , vol.87 , pp. 984-995
    • Baron, D.1    Ramstein, G.2    Chesneau, M.3
  • 52
    • 84893583540 scopus 로고    scopus 로고
    • Urinary cellmRNA profiles predictive of human kidney allograft status
    • Lee JR,Muthukumar T, Dadhania D, et al. Urinary cellmRNA profiles predictive of human kidney allograft status. Immunol Rev. 2014;258: 218-240.
    • (2014) Immunol Rev , vol.258 , pp. 218-240
    • Lee, J.R.1    Muthukumar, T.2    Dadhania, D.3
  • 53
    • 84879776271 scopus 로고    scopus 로고
    • Urinary-cell mRNA profile and acute cellular rejection in kidney allografts
    • Suthanthiran M, Schwartz JE, Ding R, et al. Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med. 2013; 369:20-31.
    • (2013) N Engl J Med , vol.369 , pp. 20-31
    • Suthanthiran, M.1    Schwartz, J.E.2    Ding, R.3
  • 54
    • 84879540321 scopus 로고    scopus 로고
    • Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling
    • Keslar KS, Lin M, Zmijewska AA, et al. Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling. Am J Transplant. 2013;13:1891-1897.
    • (2013) Am J Transplant , vol.13 , pp. 1891-1897
    • Keslar, K.S.1    Lin, M.2    Zmijewska, A.A.3
  • 56
    • 80053303952 scopus 로고    scopus 로고
    • Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients
    • Lorenzen JM, Volkmann I, Fiedler J, et al. Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients. Am J Transplant. 2011;11:2221-2227.
    • (2011) Am J Transplant , vol.11 , pp. 2221-2227
    • Lorenzen, J.M.1    Volkmann, I.2    Fiedler, J.3
  • 57
    • 80053338178 scopus 로고    scopus 로고
    • MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA
    • Scian MJ, Maluf DG, David KG, et al. MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA. Am J Transplant. 2011;11:2110-2122.
    • (2011) Am J Transplant , vol.11 , pp. 2110-2122
    • Scian, M.J.1    Maluf, D.G.2    David, K.G.3
  • 58
    • 84895902220 scopus 로고    scopus 로고
    • The urine microRNA profile may help monitor post-transplant renal graft function
    • Maluf DG, Dumur CI, Suh JL, et al. The urine microRNA profile may help monitor post-transplant renal graft function. Kidney Int. 2014;85: 439-449.
    • (2014) Kidney Int , vol.85 , pp. 439-449
    • Maluf, D.G.1    Dumur, C.I.2    Suh, J.L.3
  • 59
    • 84999089899 scopus 로고    scopus 로고
    • Developing renal allograft surveillance strategies-urinary biomarkers of cellular rejection
    • Hirt-Minkowski P, De Serres SA, Ho J. Developing renal allograft surveillance strategies-urinary biomarkers of cellular rejection. Can J Kidney Health Dis. 2015;2:28.
    • (2015) Can J Kidney Health Dis , vol.2 , pp. 28
    • Hirt-Minkowski, P.1    De Serres, S.A.2    Ho, J.3
  • 60
    • 79960869429 scopus 로고    scopus 로고
    • Identification of 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods
    • Johnston O, Cassidy H, O'Connell S, et al. Identification of 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods. Proteomics Clin Appl. 2011;5:422-431.
    • (2011) Proteomics Clin Appl , vol.5 , pp. 422-431
    • Johnston, O.1    Cassidy, H.2    O'Connell, S.3
  • 61
    • 59949089336 scopus 로고    scopus 로고
    • Presence of urinary Haufen accurately predicts polyomavirus nephropathy
    • Singh HK, Andreoni KA,Madden V, et al. Presence of urinary Haufen accurately predicts polyomavirus nephropathy. J Am Soc Nephrol. 2009; 20:416-427.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 416-427
    • Singh, H.K.1    Andreoni, K.A.2    Madden, V.3
  • 62
    • 84942835191 scopus 로고    scopus 로고
    • Polyomavirus nephropathy: Quantitative urinary polyomavirus-Haufen testing accurately predicts the degree of intrarenal viral disease
    • Singh HK, Reisner H, Derebail VK, et al. Polyomavirus nephropathy: quantitative urinary polyomavirus-Haufen testing accurately predicts the degree of intrarenal viral disease. Transplantation. 2015; 99:609-615.
    • (2015) Transplantation , vol.99 , pp. 609-615
    • Singh, H.K.1    Reisner, H.2    Derebail, V.K.3
  • 63
    • 84958781133 scopus 로고    scopus 로고
    • The noninvasive urinary polyomavirus Haufen test predicts BK virus nephropathy in children after hematopoietic cell transplantation: A pilot study
    • [published online ahead of print February 18th, 2016]
    • Laskin BL, Singh HK, Beier UH, et al. The noninvasive urinary polyomavirus Haufen test predicts BK virus nephropathy in children after hematopoietic cell transplantation: a pilot study. [published online ahead of print February 18th, 2016]. Transplantation. 2016 doi: 10.1097/TP.0000000000001085.
    • (2016) Transplantation
    • Laskin, B.L.1    Singh, H.K.2    Beier, U.H.3
  • 64
    • 84867761385 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker of acute kidney injury: A review of the laboratory characteristics and clinical evidences
    • Clerico A, Galli C, Fortunato A, et al. Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker of acute kidney injury: a review of the laboratory characteristics and clinical evidences. Clin Chem Lab Med. 2012;50:1505-1517.
    • (2012) Clin Chem Lab Med , vol.50 , pp. 1505-1517
    • Clerico, A.1    Galli, C.2    Fortunato, A.3
  • 65
    • 85010203288 scopus 로고    scopus 로고
    • Genomic and proteomic characterization of acute kidney injury
    • Devarajan P. Genomic and proteomic characterization of acute kidney injury. Nephron. 2015;131:85-91.
    • (2015) Nephron , vol.131 , pp. 85-91
    • Devarajan, P.1
  • 66
    • 84885386649 scopus 로고    scopus 로고
    • Urinary NGAL ratio is not a sensitive biomarker for monitoring acute tubular injury in kidney transplant patients: NGAL and ATI in renal transplant patients
    • Kaufeld JK, GwinnerW, Scheffner I, et al. Urinary NGAL ratio is not a sensitive biomarker for monitoring acute tubular injury in kidney transplant patients: NGAL and ATI in renal transplant patients. J Transplant. 2012; 2012:563404.
    • (2012) J Transplant , vol.2012 , pp. 563404
    • Kaufeld, J.K.1    Gwinner, W.2    Scheffner, I.3
  • 67
    • 84898678847 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: A critical evaluation of current status
    • Haase-Fielitz A, Haase M, Devarajan P. Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status. Ann Clin Biochem. 2014;51(Pt 3):335-351.
    • (2014) Ann Clin Biochem , vol.51 , pp. 335-351
    • Haase-Fielitz, A.1    Haase, M.2    Devarajan, P.3
  • 68
    • 84876081904 scopus 로고    scopus 로고
    • BK virus-associated nephropathy: Neutrophil gelatinase-associated lipocalin as a new diagnostic tool
    • Rau S, Schonermarck U, Jager G, et al. BK virus-associated nephropathy: neutrophil gelatinase-associated lipocalin as a new diagnostic tool? Clin Transplant. 2013;27:E184-E191.
    • (2013) Clin Transplant , vol.27 , pp. E184-E191
    • Rau, S.1    Schonermarck, U.2    Jager, G.3
  • 70
    • 84965137009 scopus 로고    scopus 로고
    • Urinary biomarker incorporation into the renal angina index early in intensive care unit admission optimizes acute kidney injury prediction in critically ill children: A prospective cohort study
    • Menon S, Goldstein SL, Mottes T, et al. Urinary biomarker incorporation into the renal angina index early in intensive care unit admission optimizes acute kidney injury prediction in critically ill children: a prospective cohort study. Nephrol Dial Transplant. 2016;31:586-594.
    • (2016) Nephrol Dial Transplant , vol.31 , pp. 586-594
    • Menon, S.1    Goldstein, S.L.2    Mottes, T.3
  • 71
    • 84937760352 scopus 로고    scopus 로고
    • Increased urinary cystatinC level is associated with interstitial fibrosis and tubular atrophy in kidney allograft recipients
    • Mendes Mde F, Salgado JV, de Ribamar Lima J, et al. Increased urinary cystatinC level is associated with interstitial fibrosis and tubular atrophy in kidney allograft recipients. Clin Biochem. 2015;48:546-549.
    • (2015) Clin Biochem , vol.48 , pp. 546-549
    • Mendes Mde, F.1    Salgado, J.V.2    De Ribamar Lima, J.3
  • 72
    • 84930897482 scopus 로고    scopus 로고
    • Urinary biomarkers of chronic allograft nephropathy
    • CassidyH, Slyne J,O'Kelly P, et al.Urinary biomarkers of chronic allograft nephropathy. Proteomics Clin Appl. 2015;9:574-585.
    • (2015) Proteomics Clin Appl , vol.9 , pp. 574-585
    • Cassidy, H.1    Slyne, J.2    O'Kelly, P.3
  • 73
    • 77955981759 scopus 로고    scopus 로고
    • Early urinary CCL2 is associated with the later development of interstitial fibrosis and tubular atrophy in renal allografts
    • Ho J, Rush DN, Gibson IW, et al. Early urinary CCL2 is associated with the later development of interstitial fibrosis and tubular atrophy in renal allografts. Transplantation. 2010;90:394-400.
    • (2010) Transplantation , vol.90 , pp. 394-400
    • Ho, J.1    Rush, D.N.2    Gibson, I.W.3
  • 74
    • 84903793940 scopus 로고    scopus 로고
    • Elevated urinary CCL2: Cr at 6months is associated with renal allograft interstitial fibrosis and inflammation at 24 months
    • Ho J,Wiebe C, Gibson IW, et al. Elevated urinary CCL2: Cr at 6months is associated with renal allograft interstitial fibrosis and inflammation at 24 months. Transplantation. 2014;98:39-46.
    • (2014) Transplantation , vol.98 , pp. 39-46
    • Ho, J.1    Wiebe, C.2    Gibson, I.W.3
  • 75
    • 84989353956 scopus 로고    scopus 로고
    • Early low urinary CXCL9 and CXCL10 might predict immunological quiescence in clinically and histologically stable kidney recipients
    • Rabant M, Amrouche L, Morin L, et al. Early low urinary CXCL9 and CXCL10 might predict immunological quiescence in clinically and histologically stable kidney recipients. Am J Transplant. 2015.
    • (2015) Am J Transplant.
    • Rabant, M.1    Amrouche, L.2    Morin, L.3
  • 76
    • 84944092747 scopus 로고    scopus 로고
    • Adverse outcomes of tacrolimus withdrawal in immune-quiescent kidney transplant recipients
    • Hricik DE, Formica RN, Nickerson P, et al. Adverse outcomes of tacrolimus withdrawal in immune-quiescent kidney transplant recipients. J Am Soc Nephrol. 2015;26:3114-3122.
    • (2015) J Am Soc Nephrol , vol.26 , pp. 3114-3122
    • Hricik, D.E.1    Formica, R.N.2    Nickerson, P.3
  • 77
    • 84989310924 scopus 로고    scopus 로고
    • Proteomics for rejection diagnosis in renal transplant patients: Where are we now
    • GwinnerW,Metzger J, Husi H, et al. Proteomics for rejection diagnosis in renal transplant patients: where are we now? World J Transplant. 2016; 6:28-41.
    • (2016) World J Transplant , vol.6 , pp. 28-41
    • Gwinner, W.1    Metzger, J.2    Husi, H.3
  • 78
    • 36448982930 scopus 로고    scopus 로고
    • Diagnosis of renal allograft subclinical rejection by urine protein fingerprint analysis
    • Mao Y, Yu J, Chen J, et al. Diagnosis of renal allograft subclinical rejection by urine protein fingerprint analysis. Transpl Immunol. 2008; 18:255-259.
    • (2008) Transpl Immunol , vol.18 , pp. 255-259
    • Mao, Y.1    Yu, J.2    Chen, J.3
  • 79
    • 79957594440 scopus 로고    scopus 로고
    • Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis
    • Metzger J, Chatzikyrkou C, Broecker V, et al. Diagnosis of subclinical and clinical acute T-cell-mediated rejection in renal transplant patients by urinary proteome analysis. Proteomics Clin Appl. 2011;5:322-333.
    • (2011) Proteomics Clin Appl , vol.5 , pp. 322-333
    • Metzger, J.1    Chatzikyrkou, C.2    Broecker, V.3
  • 80
    • 28044460957 scopus 로고    scopus 로고
    • Detection of acute tubulointerstitial rejection by proteomic analysis of urinary samples in renal transplant recipients
    • Wittke S, Haubitz M,Walden M, et al. Detection of acute tubulointerstitial rejection by proteomic analysis of urinary samples in renal transplant recipients. Am J Transplant. 2005;5:2479-2488.
    • (2005) Am J Transplant , vol.5 , pp. 2479-2488
    • Wittke, S.1    Haubitz, M.2    Walden, M.3
  • 81
    • 60849083570 scopus 로고    scopus 로고
    • Temporal stability of the urinary proteome after kidney transplant: More sensitive than protein composition
    • Akkina SK, Zhang Y, Nelsestuen GL, et al. Temporal stability of the urinary proteome after kidney transplant: more sensitive than protein composition? J Proteome Res. 2009;8:94-103.
    • (2009) J Proteome Res , vol.8 , pp. 94-103
    • Akkina, S.K.1    Zhang, Y.2    Nelsestuen, G.L.3
  • 82
    • 68049101085 scopus 로고    scopus 로고
    • Application of label-free quantitative peptidomics for the identification of urinary biomarkers of kidney chronic allograft dysfunction
    • Quintana LF, Campistol JM, Alcolea MP, et al. Application of label-free quantitative peptidomics for the identification of urinary biomarkers of kidney chronic allograft dysfunction.Mol Cell Proteomics. 2009;8:1658-1673.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 1658-1673
    • Quintana, L.F.1    Campistol, J.M.2    Alcolea, M.P.3
  • 83
    • 59949097714 scopus 로고    scopus 로고
    • Urine proteomics to detect biomarkers for chronic allograft dysfunction
    • Quintana LF, Sole-Gonzalez A, Kalko SG, et al. Urine proteomics to detect biomarkers for chronic allograft dysfunction. J Am Soc Nephrol. 2009;20:428-435.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 428-435
    • Quintana, L.F.1    Sole-Gonzalez, A.2    Kalko, S.G.3
  • 84
    • 84893286386 scopus 로고    scopus 로고
    • The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomics
    • Sigdel TK, Salomonis N, Nicora CD, et al. The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomics. Mol Cell Proteomics. 2014;13: 621-631.
    • (2014) Mol Cell Proteomics , vol.13 , pp. 621-631
    • Sigdel, T.K.1    Salomonis, N.2    Nicora, C.D.3
  • 85
    • 77749252489 scopus 로고    scopus 로고
    • Diagnosis of c4d + renal allograft acute humoral rejection by urine protein fingerprint analysis
    • Yang H, Mao Y, Yu J, et al. Diagnosis of c4d + renal allograft acute humoral rejection by urine protein fingerprint analysis. J Int Med Res. 2010;38:176-186.
    • (2010) J Int Med Res , vol.38 , pp. 176-186
    • Yang, H.1    Mao, Y.2    Yu, J.3
  • 86
    • 84863201794 scopus 로고    scopus 로고
    • Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation
    • Pisitkun T, Gandolfo MT, Das S, et al. Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Proteomics Clin Appl. 2012;6:268-278.
    • (2012) Proteomics Clin Appl , vol.6 , pp. 268-278
    • Pisitkun, T.1    Gandolfo, M.T.2    Das, S.3
  • 87
    • 33750705276 scopus 로고    scopus 로고
    • Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy
    • Jahnukainen T, Malehorn D, Sun M, et al. Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy. J Am Soc Nephrol. 2006;17:3248-3256.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3248-3256
    • Jahnukainen, T.1    Malehorn, D.2    Sun, M.3
  • 88
    • 48349142006 scopus 로고    scopus 로고
    • Acute tubular injury in protocol biopsies of renal grafts: Prevalence, associated factors and effect on long-term function
    • Gwinner W, Hinzmann K, Erdbruegger U, et al. Acute tubular injury in protocol biopsies of renal grafts: prevalence, associated factors and effect on long-term function. Am J Transplant. 2008;8:1684-1693.
    • (2008) Am J Transplant , vol.8 , pp. 1684-1693
    • Gwinner, W.1    Hinzmann, K.2    Erdbruegger, U.3
  • 89
    • 84859927990 scopus 로고    scopus 로고
    • Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis
    • Wang M, Jin Q, Tu H, et al. Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis. Int Urol Nephrol. 2011;43:1009-1017.
    • (2011) Int Urol Nephrol , vol.43 , pp. 1009-1017
    • Wang, M.1    Jin, Q.2    Tu, H.3
  • 90
    • 62749180220 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomic analysis of urine in acute kidney injury following cardiopulmonary bypass: A nested case-control study
    • Ho J, Lucy M, Krokhin O, et al. Mass spectrometry-based proteomic analysis of urine in acute kidney injury following cardiopulmonary bypass: a nested case-control study. Am J Kidney Dis. 2009;53:584-595.
    • (2009) Am J Kidney Dis , vol.53 , pp. 584-595
    • Ho, J.1    Lucy, M.2    Krokhin, O.3
  • 91
    • 78649641356 scopus 로고    scopus 로고
    • Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury
    • Metzger J, Kirsch T, Schiffer E, et al. Urinary excretion of twenty peptides forms an early and accurate diagnostic pattern of acute kidney injury. Kidney Int. 2010;78:1252-1262.
    • (2010) Kidney Int , vol.78 , pp. 1252-1262
    • Metzger, J.1    Kirsch, T.2    Schiffer, E.3
  • 92
    • 77949411194 scopus 로고    scopus 로고
    • Two-dimensional difference gel electrophoresis urinary proteomic profile in the search of nonimmune chronic allograft dysfunction biomarkers
    • Bañón-Maneus E, Diekmann F, Carrascal M, et al. Two-dimensional difference gel electrophoresis urinary proteomic profile in the search of nonimmune chronic allograft dysfunction biomarkers. Transplantation. 2010; 89:548-558.
    • (2010) Transplantation , vol.89 , pp. 548-558
    • Bañón-Maneus, E.1    Diekmann, F.2    Carrascal, M.3
  • 93
    • 50849117844 scopus 로고    scopus 로고
    • Urinary proteomic analysis of chronic allograft nephropathy
    • O'Riordan E, Orlova TN, Mendelev N, et al. Urinary proteomic analysis of chronic allograft nephropathy. Proteomics Clin Appl. 2008;2:1025-1035.
    • (2008) Proteomics Clin Appl , vol.2 , pp. 1025-1035
    • O'Riordan, E.1    Orlova, T.N.2    Mendelev, N.3
  • 94
    • 84919794730 scopus 로고    scopus 로고
    • Biomarkers of calcineurin inhibitor nephrotoxicity in transplantation
    • Fernando M, Peake PW, Endre ZH. Biomarkers of calcineurin inhibitor nephrotoxicity in transplantation. Biomark Med. 2014;8:1247-1262.
    • (2014) Biomark Med , vol.8 , pp. 1247-1262
    • Fernando, M.1    Peake, P.W.2    Endre, Z.H.3
  • 95
    • 84889009158 scopus 로고    scopus 로고
    • Urine podocyte mRNAs, proteinuria, and progression in human glomerular diseases
    • Wickman L, Afshinnia F, Wang SQ, et al. Urine podocyte mRNAs, proteinuria, and progression in human glomerular diseases. J Am Soc Nephrol. 2013;24:2081-2095.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 2081-2095
    • Wickman, L.1    Afshinnia, F.2    Wang, S.Q.3
  • 96
    • 65649153051 scopus 로고    scopus 로고
    • Urine podocyte mRNAs mark progression of renal disease
    • Sato Y, Wharram BL, Lee SK, et al. Urine podocyte mRNAs mark progression of renal disease. J Am Soc Nephrol. 2009;20:1041-1052.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1041-1052
    • Sato, Y.1    Wharram, B.L.2    Lee, S.K.3
  • 97
    • 84878917311 scopus 로고    scopus 로고
    • Podocyturia predates proteinuria and clinical features of preeclampsia: Longitudinal prospective study
    • Craici IM, Wagner SJ, Bailey KR, et al. Podocyturia predates proteinuria and clinical features of preeclampsia: longitudinal prospective study. Hypertension. 2013;61:1289-1296.
    • (2013) Hypertension , vol.61 , pp. 1289-1296
    • Craici, I.M.1    Wagner, S.J.2    Bailey, K.R.3
  • 99
    • 84987679862 scopus 로고    scopus 로고
    • Urinary osteoprotegerin: A potential biomarker of lupus nephritis disease activity
    • Gupta R, Aggarwal A, Sinha S, et al. Urinary osteoprotegerin: a potential biomarker of lupus nephritis disease activity. Lupus. 2016.
    • (2016) Lupus.
    • Gupta, R.1    Aggarwal, A.2    Sinha, S.3
  • 100
    • 84958539961 scopus 로고    scopus 로고
    • Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis
    • Vadasz Z, Goldeberg Y, Halasz K, et al. Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis. Clin Immunol. 2016;164:114-118.
    • (2016) Clin Immunol , vol.164 , pp. 114-118
    • Vadasz, Z.1    Goldeberg, Y.2    Halasz, K.3
  • 101
    • 84864454184 scopus 로고    scopus 로고
    • Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis
    • Brunner HI, Bennett MR,Mina R, et al. Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritis. Arthritis Rheum. 2012;64:2687-2697.
    • (2012) Arthritis Rheum , vol.64 , pp. 2687-2697
    • Brunner, H.I.1    Bennett, M.R.2    Mina, R.3
  • 102
    • 84859049370 scopus 로고    scopus 로고
    • Near normalization of metabolic and functional features of the central nervous system in type 1 diabetic patients with end-stage renal disease after kidney-pancreas transplantation
    • Fiorina P, Vezzulli P, Bassi R, et al. Near normalization of metabolic and functional features of the central nervous system in type 1 diabetic patients with end-stage renal disease after kidney-pancreas transplantation. Diabetes Care. 2012;35:367-374.
    • (2012) Diabetes Care , vol.35 , pp. 367-374
    • Fiorina, P.1    Vezzulli, P.2    Bassi, R.3
  • 103
    • 33847642892 scopus 로고    scopus 로고
    • Altered kidney graft highenergy phosphate metabolism in kidney-transplanted end-stage renal disease type 1 diabetic patients: A cross-sectional analysis of the effect of kidney alone and kidney-pancreas transplantation
    • Fiorina P, Perseghin G, De Cobelli F, et al. Altered kidney graft highenergy phosphate metabolism in kidney-transplanted end-stage renal disease type 1 diabetic patients: a cross-sectional analysis of the effect of kidney alone and kidney-pancreas transplantation. Diabetes Care. 2007;30:597-603.
    • (2007) Diabetes Care , vol.30 , pp. 597-603
    • Fiorina, P.1    Perseghin, G.2    De Cobelli, F.3
  • 104
    • 84956925299 scopus 로고    scopus 로고
    • Fluorodeoxyglucose F(18) positron emission tomography coupled with computed tomography in suspected acute renal allograft rejection
    • Lovinfosse P, Weekers L, Bonvoisin C, et al. Fluorodeoxyglucose F(18) positron emission tomography coupled with computed tomography in suspected acute renal allograft rejection. Am J Transplant. 2016;16: 310-316.
    • (2016) Am J Transplant , vol.16 , pp. 310-316
    • Lovinfosse, P.1    Weekers, L.2    Bonvoisin, C.3
  • 105
    • 0035967217 scopus 로고    scopus 로고
    • Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine
    • Li B, Hartono C, Ding R, et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med. 2001;344:947-954.
    • (2001) N Engl J Med , vol.344 , pp. 947-954
    • Li, B.1    Hartono, C.2    Ding, R.3
  • 106
    • 0038586415 scopus 로고    scopus 로고
    • Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts
    • Muthukumar T, Ding R, Dadhania D, et al. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation. 2003;75:1565-1570.
    • (2003) Transplantation , vol.75 , pp. 1565-1570
    • Muthukumar, T.1    Ding, R.2    Dadhania, D.3
  • 107
    • 0038350649 scopus 로고    scopus 로고
    • Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection
    • Dadhania D, Muthukumar T, Ding R, et al. Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection. Transplantation. 2003;75:1752-1754.
    • (2003) Transplantation , vol.75 , pp. 1752-1754
    • Dadhania, D.1    Muthukumar, T.2    Ding, R.3
  • 108
    • 0037469042 scopus 로고    scopus 로고
    • CD103 mRNA levels in urinary cells predict acute rejection of renal allografts
    • Ding R, Li B, Muthukumar T, et al. CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation. 2003;75: 1307-1312.
    • (2003) Transplantation , vol.75 , pp. 1307-1312
    • Ding, R.1    Li, B.2    Muthukumar, T.3
  • 109
    • 3042614142 scopus 로고    scopus 로고
    • Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection
    • Kotsch K, Mashreghi MF, Bold G, et al. Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection. Transplantation. 2004;77:1866-1875.
    • (2004) Transplantation , vol.77 , pp. 1866-1875
    • Kotsch, K.1    Mashreghi, M.F.2    Bold, G.3
  • 110
    • 2442652560 scopus 로고    scopus 로고
    • Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine
    • Tatapudi RR, Muthukumar T, Dadhania D, et al. Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int. 2004;65:2390-2397.
    • (2004) Kidney Int , vol.65 , pp. 2390-2397
    • Tatapudi, R.R.1    Muthukumar, T.2    Dadhania, D.3
  • 111
    • 28244444532 scopus 로고    scopus 로고
    • Messenger RNA for FOXP3 in the urine of renal-allograft recipients
    • Muthukumar T, Dadhania D, Ding R, et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med. 2005;353: 2342-2351.
    • (2005) N Engl J Med , vol.353 , pp. 2342-2351
    • Muthukumar, T.1    Dadhania, D.2    Ding, R.3
  • 112
    • 33646508545 scopus 로고    scopus 로고
    • Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short-and longterm graft function
    • Matz M, Beyer J, Wunsch D, et al. Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short-and longterm graft function. Kidney Int. 2006;69:1683-1690.
    • (2006) Kidney Int , vol.69 , pp. 1683-1690
    • Matz, M.1    Beyer, J.2    Wunsch, D.3
  • 113
    • 33746873277 scopus 로고    scopus 로고
    • Urinary cytotoxic molecular markers for a noninvasive diagnosis in acute renal transplant rejection
    • Yannaraki M, Rebibou JM, Ducloux D, et al. Urinary cytotoxic molecular markers for a noninvasive diagnosis in acute renal transplant rejection. Transpl Int. 2006;19:759-768.
    • (2006) Transpl Int , vol.19 , pp. 759-768
    • Yannaraki, M.1    Rebibou, J.M.2    Ducloux, D.3
  • 114
    • 33846226405 scopus 로고    scopus 로고
    • Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation
    • SeilerM, Brabcova I, Viklicky O, et al. Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation. Am J Transplant. 2007;7:423-433.
    • (2007) Am J Transplant , vol.7 , pp. 423-433
    • Seiler, M.1    Brabcova, I.2    Viklicky, O.3
  • 115
    • 34248640135 scopus 로고    scopus 로고
    • High expression of Tim-3 mRNA in urinary cells from kidney transplant recipients with acute rejection
    • Renesto PG, Ponciano VC, Cenedeze MA, et al. High expression of Tim-3 mRNA in urinary cells from kidney transplant recipients with acute rejection. Am J Transplant. 2007;7:1661-1665.
    • (2007) Am J Transplant , vol.7 , pp. 1661-1665
    • Renesto, P.G.1    Ponciano, V.C.2    Cenedeze, M.A.3
  • 116
    • 58849097202 scopus 로고    scopus 로고
    • Noninvasive Tim-3 messenger RNA evaluation in renal transplant recipients with graft dysfunction
    • Manfro RC, Aquino-Dias EC, Joelsons G, et al. Noninvasive Tim-3 messenger RNA evaluation in renal transplant recipients with graft dysfunction. Transplantation. 2008;86:1869-1874.
    • (2008) Transplantation , vol.86 , pp. 1869-1874
    • Manfro, R.C.1    Aquino-Dias, E.C.2    Joelsons, G.3
  • 117
    • 61849116099 scopus 로고    scopus 로고
    • Transcriptional profiles in urine during acute rejection, bacteriuria, CMV infection and stable graft function after renal transplantation
    • Ozbay A, Torring C, Olsen R, et al. Transcriptional profiles in urine during acute rejection, bacteriuria, CMV infection and stable graft function after renal transplantation. Scand J Immunol. 2009;69:357-365.
    • (2009) Scand J Immunol , vol.69 , pp. 357-365
    • Ozbay, A.1    Torring, C.2    Olsen, R.3
  • 118
    • 78650842077 scopus 로고    scopus 로고
    • Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts
    • Afaneh C, Muthukumar T, Lubetzky M, et al. Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts. Transplantation. 2010;90:1381-1387.
    • (2010) Transplantation , vol.90 , pp. 1381-1387
    • Afaneh, C.1    Muthukumar, T.2    Lubetzky, M.3
  • 119
    • 78049479779 scopus 로고    scopus 로고
    • Urinary granzyme A mRNA is a biomarker to diagnose subclinical and acute cellular rejection in kidney transplant recipients
    • van Ham SM, Heutinck KM, Jorritsma T, et al. Urinary granzyme A mRNA is a biomarker to diagnose subclinical and acute cellular rejection in kidney transplant recipients. Kidney Int. 2010;78:1033-1040.
    • (2010) Kidney Int , vol.78 , pp. 1033-1040
    • Van Ham, S.M.1    Heutinck, K.M.2    Jorritsma, T.3
  • 120
    • 84905676008 scopus 로고    scopus 로고
    • Urinary cell mRNA profiles and differential diagnosis of acute kidney graft dysfunction
    • Matignon M, Ding R, Dadhania DM, et al. Urinary cell mRNA profiles and differential diagnosis of acute kidney graft dysfunction. J Am Soc Nephrol. 2014;25:1586-1597.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 1586-1597
    • Matignon, M.1    Ding, R.2    Dadhania, D.M.3
  • 121
    • 84884907939 scopus 로고    scopus 로고
    • Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury
    • Hricik DE, Nickerson P, Formica RN, et al.Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury. Am J Transplant. 2013;13:2634-2644.
    • (2013) Am J Transplant , vol.13 , pp. 2634-2644
    • Hricik, D.E.1    Nickerson, P.2    Formica, R.N.3
  • 122
    • 1442289494 scopus 로고    scopus 로고
    • Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction
    • Hu H, Aizenstein BD, Puchalski A, et al. Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction. Am J Transplant. 2004;4:432-437.
    • (2004) Am J Transplant , vol.4 , pp. 432-437
    • Hu, H.1    Aizenstein, B.D.2    Puchalski, A.3
  • 123
    • 26944443736 scopus 로고    scopus 로고
    • Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG)
    • Hauser IA, Spiegler S, Kiss E, et al. Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG). J Am Soc Nephrol. 2005;16:1849-1858.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1849-1858
    • Hauser, I.A.1    Spiegler, S.2    Kiss, E.3
  • 124
    • 56549108678 scopus 로고    scopus 로고
    • Urinary fractalkine is a marker of acute rejection
    • Peng W, Chen J, Jiang Y, et al. Urinary fractalkine is a marker of acute rejection. Kidney Int. 2008;74:1454-1460.
    • (2008) Kidney Int , vol.74 , pp. 1454-1460
    • Peng, W.1    Chen, J.2    Jiang, Y.3
  • 125
    • 66249122732 scopus 로고    scopus 로고
    • Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis
    • Schaub S, Nickerson P, Rush D, et al. Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis. Am J Transplant. 2009;9: 1347-1353.
    • (2009) Am J Transplant , vol.9 , pp. 1347-1353
    • Schaub, S.1    Nickerson, P.2    Rush, D.3
  • 126
    • 67649635344 scopus 로고    scopus 로고
    • Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine
    • Hu H, Kwun J, Aizenstein BD, et al. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-1820.
    • (2009) Transplantation , vol.87 , pp. 1814-1820
    • Hu, H.1    Kwun, J.2    Aizenstein, B.D.3
  • 127
    • 80053328081 scopus 로고    scopus 로고
    • Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection
    • Jackson JA, Kim EJ, Begley B, et al. Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection. Am J Transplant. 2011;11:2228-2234.
    • (2011) Am J Transplant , vol.11 , pp. 2228-2234
    • Jackson, J.A.1    Kim, E.J.2    Begley, B.3
  • 128
    • 80054771957 scopus 로고    scopus 로고
    • Validation of urinary CXCL10 as a marker of borderline, subclinical, and clinical tubulitis
    • Ho J, Rush DN, Karpinski M, et al. Validation of urinary CXCL10 as a marker of borderline, subclinical, and clinical tubulitis. Transplantation. 2011;92:878-882.
    • (2011) Transplantation , vol.92 , pp. 878-882
    • Ho, J.1    Rush, D.N.2    Karpinski, M.3
  • 129
    • 84863224247 scopus 로고    scopus 로고
    • Detection of clinical and subclinical tubulo-interstitial inflammation by the urinary CXCL10 chemokine in a real-life setting
    • Hirt-Minkowski P,Amico P, Ho J, et al. Detection of clinical and subclinical tubulo-interstitial inflammation by the urinary CXCL10 chemokine in a real-life setting. Am J Transplant. 2012;12:1811-1823.
    • (2012) Am J Transplant , vol.12 , pp. 1811-1823
    • Hirt-Minkowski, P.1    Amico, P.2    Ho, J.3
  • 130
    • 84930182290 scopus 로고    scopus 로고
    • Elevated urinary CXCL10-tocreatinine ratio is associated with subclinical and clinical rejection in pediatric renal transplantation
    • Blydt-Hansen TD, Gibson IW, Gao A, et al. Elevated urinary CXCL10-tocreatinine ratio is associated with subclinical and clinical rejection in pediatric renal transplantation. Transplantation. 2015;99:797-804.
    • (2015) Transplantation , vol.99 , pp. 797-804
    • Blydt-Hansen, T.D.1    Gibson, I.W.2    Gao, A.3
  • 131
    • 0032530709 scopus 로고    scopus 로고
    • Cytotoxic lymphocyte gene expression in peripheral blood leukocytes correlates with rejecting renal allografts
    • Vasconcellos LM, Schachter AD, Zheng XX, et al. Cytotoxic lymphocyte gene expression in peripheral blood leukocytes correlates with rejecting renal allografts. Transplantation. 1998;66:562-566.
    • (1998) Transplantation , vol.66 , pp. 562-566
    • Vasconcellos, L.M.1    Schachter, A.D.2    Zheng, X.X.3
  • 132
    • 0034663959 scopus 로고    scopus 로고
    • Heightened CD40 ligand gene expression in peripheral CD4+ T cells from patients with kidney allograft rejection
    • Shoker A, George D, Yang H, et al. Heightened CD40 ligand gene expression in peripheral CD4+ T cells from patients with kidney allograft rejection. Transplantation. 2000;70:497-505.
    • (2000) Transplantation , vol.70 , pp. 497-505
    • Shoker, A.1    George, D.2    Yang, H.3
  • 133
    • 0034667745 scopus 로고    scopus 로고
    • Cytokine and cytotoxic molecule gene expression determined in peripheral blood mononuclear cells in the diagnosis of acute renal rejection
    • Dugré FJ, Gaudreau S, Belles-Isles M, et al. Cytokine and cytotoxic molecule gene expression determined in peripheral blood mononuclear cells in the diagnosis of acute renal rejection. Transplantation. 2000;70:1074-1080.
    • (2000) Transplantation , vol.70 , pp. 1074-1080
    • Dugré, F.J.1    Gaudreau, S.2    Belles-Isles, M.3
  • 134
    • 0037106494 scopus 로고    scopus 로고
    • Quantitative detection of T-cell activation markers by real-time PCR in renal transplant rejection and correlation with histopathologic evaluation
    • Sabek O, Dorak MT, Kotb M, et al. Quantitative detection of T-cell activation markers by real-time PCR in renal transplant rejection and correlation with histopathologic evaluation. Transplantation. 2002;74: 701-707.
    • (2002) Transplantation , vol.74 , pp. 701-707
    • Sabek, O.1    Dorak, M.T.2    Kotb, M.3
  • 135
    • 0036257565 scopus 로고    scopus 로고
    • Granzyme B, FAS-ligand and perforin expression during acute cellular rejection episodes after kidney transplantation: Comparison between blood and renal aspirates
    • Netto MV, Fonseca BA, Dantas M, et al. Granzyme B, FAS-ligand and perforin expression during acute cellular rejection episodes after kidney transplantation: comparison between blood and renal aspirates. Transplant Proc. 2002;34:476-478.
    • (2002) Transplant Proc , vol.34 , pp. 476-478
    • Netto, M.V.1    Fonseca, B.A.2    Dantas, M.3
  • 136
    • 20944435138 scopus 로고    scopus 로고
    • Gene expression of perforin by peripheral blood lymphocytes as a marker of acute rejection
    • Shin GT, Kim SJ, Lee TS, et al. Gene expression of perforin by peripheral blood lymphocytes as a marker of acute rejection. Nephron Clin Pract. 2005;100:c63-c70.
    • (2005) Nephron Clin Pract , vol.100 , pp. c63-c70
    • Shin, G.T.1    Kim, S.J.2    Lee, T.S.3
  • 137
    • 33750014237 scopus 로고    scopus 로고
    • Noninvasive diagnosis of cellular and antibody-mediated rejection by perforin and granzyme B in renal allografts
    • Veale JL, Liang LW, Zhang Q, et al. Noninvasive diagnosis of cellular and antibody-mediated rejection by perforin and granzyme B in renal allografts. Hum Immunol. 2006;67:777-786.
    • (2006) Hum Immunol , vol.67 , pp. 777-786
    • Veale, J.L.1    Liang, L.W.2    Zhang, Q.3
  • 138
    • 84875943895 scopus 로고    scopus 로고
    • Expression of miR-142-5p in peripheral blood mononuclear cells from renal transplant patients with chronic antibody-mediated rejection
    • Danger R, Paul C, Giral M, et al. Expression of miR-142-5p in peripheral blood mononuclear cells from renal transplant patients with chronic antibody-mediated rejection. PLoS One. 2013;8:e60702.
    • (2013) PLoS One , vol.8 , pp. e60702
    • Danger, R.1    Paul, C.2    Giral, M.3


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