Cytotoxic lymphocyte gene expression in peripheral blood leukocytes correlates with rejecting renal allografts

Transplantation

Volumn 66, Issue 5, 1998, Pages 562-566

  Vasconcellos, Lauro M ^a   Asher, F ^a,b   Schachter, D ^a,b   Zheng, Xin Xiao ^a   Vasconcellos, Lucia H B ^c   Shapiro, Michael ^a   Harmon, William E ^b   Strom, Terry B ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A;

ADULT; ALLOTRANSPLANTATION; ARTICLE; CHILD; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; IMMUNOPATHOGENESIS; IMMUNOREGULATION; KIDNEY BIOPSY; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; NEPHROTOXICITY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; CHILD; FAS LIGAND PROTEIN; GENE EXPRESSION; GRAFT REJECTION; GRANZYMES; HUMANS; KIDNEY TRANSPLANTATION; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0032530709     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199809150-00002     Document Type: Article

References (24)

1. Cecka JM, Terasaki PI. The UNOS scientific renal transplant registry. In: Cecka J, Terasaki P, eds. Clinical transplants 1994. Los Angeles: UCLA Tissue Typing Laboratory, 1994: 1.
2. Almond PS, Matas A, Gillingham KJ, et al. Risk factors for chronic rejection in renal allograft recipients. Transplantation 1993; 55: 752.
3. O'Connell PJ, Pacheco-Silva A, Nickerson PW, et al. Unmodified pancreatic islet allograft rejection results in the preferential expression of certain T cell activation transcripts. J Immunol 1993; 150: 1093.
4. Strehlau J, Pavlakis M, Lipman M, et al. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc Natl Acad Sci USA 1997; 94(2): 695.
5. Leidtke W, Battistini L, Brosnan CF, Raine CS. A comparison of methods for RNA extraction from lymphocytes for RT-PCR. PCR Methods Appl 1994; 3(3): 185.
6. Lipman ML, Stevens AC, Strom TB. Heightened intragraft CTL expression in acutely rejecting renal allografts. J Immunol 1994; 152: 5120.
7. Pavlakis M, Strehlau J, Lipman M, Strom TB. Use of intragraft gene expression in the diagnosis of kidney allograft rejection. Transplant Proc 1996; 28(4): 2019.
8. Solez K, Benediktsson H, Cavallo T, et al. Report of the Third Banff Conference on Allograft Pathology (July 20-24, 1995) on classification and lesion scoring in renal allograft pathology. Transplant Proc 1996; 28(1): 441.
9. Helderman JH, Hernandez J, Sagalowsky A, et al. Confirmation of the utility of fine needle aspiration of the renal allograft. Kidney Int 1988; 34: 376.
10. Rukavina D, Balen-Marunic S, Rubesa G, Orlic P, Vujaklija K, Podack ER. Perform expression in peripheral blood lymphocytes in rejecting and tolerant kidney transplant recipients. Transplantation 1996; 61: 285.
11. Jeyarajah DR, Kadakia RA, O'Toole K, et al. Changes in urinary cytokine mRNA profile after successful therapy for acute cellular renal allograft rejection. Transplant Proc 1995; 27: 887.
12. Roberti I, Reisman L, Burrows L, Lieberman KV. Urine cytology and urine flow cytometry in renal transplantation: a prospective double blind study. Transplantation 1995; 59: 495.
13. Rush DN, Henry SF, Jeffery JR. Histological findings in early routine biopsies of stable renal allograft recipients. Transplantation 1994; 57(2): 208.
14. Rush DN, Jeffery JR, Gough J. Sequential protocol biopsies in renal transplant recipients: clinicopathological correlations using the Banff schema. Transplantation 1995; 59(4): 511.
15. Persechini PM, Young JDE, Almers W. Membrane channel formation by the lymphocyte pore-forming proteins: comparison between susceptible and resistant target cells. J Cell Biol 1990; 110: 2109.
16. Pasternack MS, Eisen HR. A novel serine esterase expressed by cytotoxic T lymphocytes. Nature 1985; 314: 743.
17. Nakajima H, Henkart PA. Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown. J Immunol 1994; 152: 1057.
18. Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75: 1169.
19. Suda T, Nagata S. Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 1994; 179: 873.
20. 2+-independent T cell-mediated cytotoxicity. J Exp Med 1993; 177: 195.
21. Abecassis MM, Koffron AJ, Kaplan B, et al. The role of PCR in the diagnosis and management of CMV in solid organ recipients. Transplantation 1997; 63: 275.
22. Fox JC, Griffiths PD, Emery VC. Quantification of human cytomegalovirus DNA using polymerase chain reaction. J Gen Virol 1992; 76: 309.
23. Saad R, Gritsch HA, Shapiro R, et al. Clinical significance of renal allograft biopsies with "borderline changes," as defined in the Banff schema. Transplantation 1997; 64: 992.
24. Colvin RB, Cohen AH, Saiontz C, et al. Evaluation of pathologic criteria for acute renal allograft rejection: reproducibility, sensitivity, and clinical correlation. J Am Soc Nephrol 1997; 8(12): 1930.