Can immune cell function assay identify patients at risk of infection or rejection? A meta-analysis

Transplantation

Volumn 93, Issue 7, 2012, Pages 737-743

  Ling, Xiaoting ^a   Xiong, Jun ^b   Liang, Wenhua ^a   Schroder, Paul M ^c   Wu, Linwei ^a   Ju, Weiqiang ^a   Kong, Yuan ^a   Shang, Yushu ^a   Guo, Zhiyong ^a   He, Xiaoshun ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Immuknow; Infection; Metaanalysis; Rejection

Indexed keywords

ACCURACY; ARTICLE; CD4+ T LYMPHOCYTE; CELL ASSAY; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; GRAFT REJECTION; HEART TRANSPLANTATION; HUMAN; IMMUNE CELL FUNCTION ASSAY; INFECTION; INFECTION RISK; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LUNG TRANSPLANTATION; META ANALYSIS; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; COMMUNICABLE DISEASES; GRAFT REJECTION; HUMANS; LIKELIHOOD FUNCTIONS; LYMPHOCYTE ACTIVATION; MONITORING, IMMUNOLOGIC; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; RISK FACTORS; ROC CURVE; SENSITIVITY AND SPECIFICITY; TRANSPLANTS; TREATMENT OUTCOME;

EID: 84863416747     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3182466248     Document Type: Article

References (33)

1. Brick C, Atouf O, Benseffaj N, et al. Rejection of kidney graft: Mechanism and prevention. Nephrol Ther 2011; 7: 18
2. Grulich AE, van Leeuwen MT, Falster MO, et al. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplantrecipients: A meta-analysis. Lancet 2007; 370: 59
3. Shapiro R. End-stage renal disease in 2010: Innovative approaches to improve outcomes in transplantation. Nat Rev Nephrol 2011; 7: 68
4. Barry M, Bleackley RC. Cytotoxic T lymphocytes: All roads lead to death. Nat Rev Immunol 2002; 2: 401
5. Kowalski RJ, Post DR, Mannon RB, et al. Assessing relative risks of infection and rejection: A meta-analysis using an immune function assay. Transplantation 2006; 82: 663
6. Gautam A, Fischer SA, Yango AF, et al. Cell mediated immunity (CMI) and post transplant viral infections-Role of a functional immune assay to titrate immunosuppression. Int Immunopharmacol 2006; 6: 2023
7. Thai NL, Blisard D, Tom K, et al. Pancreas transplantation under alemtuzumab (campath-1H) and tacrolimus: Correlation between low Tcell responses and infection. Transplantation 2006; 82: 1649
8. Husain S, Raza K, Pilewski JM, et al. Experience with immune monitoring in lung transplant recipients: Correlation of low immune function with infection. Transplantation 2009; 87: 1852
9. Sánchez-Velasco P, Rodrigo E, Valero R, et al. Intracellular ATP concertrations of CD4 cells in kidney transplant patients with and without infection. Clin Transplant 2008; 22: 55
10. Xue F, Zhang J, Han L, et al. Immune cell functional assay in monitoring of adult liver transplantation recipients with infection. Transplantation 2010; 89: 620
11. Dong JY, Yin H, Li RD, et al. The relationship between adenosine triphosphate within CD4-T lymphocytes and acute rejection after liver transplantation. Clin Transplant 2011; 25: 292
12. Huskey J, Gralla J, Wiseman AC. Single time point immune function assay (ImmuKnow TM) testing does not aid in the prediction of future opportunistic infections or acute rejection. Clin J AmSoc Nephrol 2011; 6: 423
13. Serban G, Whittaker V, Fan J, et al. Significance of immune cell function monitoring in renal transplantation after thymoglobulin induction therapy. Hum Immunol 2009; 70: 882
14. De Paolis P, Favarò A, Piola A, et al. "Immuknow" to measurement of cell-mediated immunity in renal transplant recipients undergoing short-term evaluation. Transplant Proc 2011; 43: 1013
15. Torío A, Fernández EJ, Montes-Ares O, et al. Lack of association of immune cell function test with rejection in kidney transplantation. Transplant Proc 2011; 43: 2168
16. Hashimoto K, Miller C, Hirose K, et al. Measurement of CD4+T-cell function in predicting allograft rejection and recurrent hepatitis C after liver transplantation. Clin Transplant 2010; 24: 701
17. Hwang S, Kim KH, Song GW, et al. Peritransplant monitoring of immune cell function in adult living donor liver transplantation. Transplant Proc 2010; 42: 2567
18. Mizuno S, Hamada T, Nakatani K, et al. Monitoring periheral blood CD4+adenosine triphosphate activity after living donor liver transplantation: Impact of combination assays of immune function and CYP3A5 genotype. J Hepatobiliary Pancreat Sci 2011; 18: 226
19. Bhorade SM, Janata K, Vigneswaran WT, et al. Cylex ImmuKnow assay levels are lower in lung transplant recipients with infection. J Heart Lung Transplant 2008; 27: 990
20. Kobashigawa JA, Kiyosaki KK, Patel JK, et al. Benefit of immune monitoring in heart transplant patients using ATP production in activated lymphocytes. J Heart Lung Transplant 2010; 29: 504
21. Berglund D, Bengtsson M, Biglarnia A, et al. Screening of mortality in transplant patients using an assay for immune function. Transpl Immunol 2011; 24: 246
22. Cheng JW, Shi YH, Fan J, et al. An immune function assay predicts post-transplant recurrence in patients with hepatocellular carcinoma. J Cancer Res Clin Oncol 2011; 137: 1445
23. Zhou H, Wu Z, Ma L, et al. Assessing immunologic function through CD4 T-lymphocyte adenosine triphosphate levels by ImmuKnow assay in Chinese patients following renal transplantation. Transplant Proc 2011; 43: 2574
24. Cabrera R, Ararat M, Soldevila-Pico C, et al. Using an immune functional assay to differentiate acute cellular rejection from recurrent hepatitis C in liver transplant patients. Liver Transpl 2009; 15: 216
25. Bossuyt PM, Reitsma JB, Bruns DE, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative. BMJ 2003; 326: 41
26. Whiting P, Rutjes AW, Reitsma JB, et al. The development of QUADAS:A tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol 2003; 3: 25
27. Altman DG, Bland JM. Diagnostic tests 1: Sensitivity and specificity. BMJ 1994; 308: 1552 (Pubitemid 24178459)
28. Deeks JJ, Altman DG. Diagnostic tests 4: Likelihood ratios. BMJ 2004; 329: 168
29. Glas AS, Lijmer JG, Prins MH, et al. The diagnostic odds ratio: A single indicator of test performance. J Clin Epidemiol 2003; 56: 1129
30. Moses LE, Shapiro D, Littenberg B. Combining independent studies of a diagnostic test into a summary ROC curve: Data-analytic approaches and some additional considerations. Stat Med 1993; 12: 1293
31. DerSimonian R, Kacker R. Random-effects model for meta-analysis of clinical trials: An update. Contemp Clin Trials 2007; 28: 105
32. Devillé WL, Buntinx F, Bouter LM, et al. Conducting systematic reviews of diagnostic studies: Didactic guidelines. BMC Med Res Methodol 2002; 2: 9
33. Egger M, Davey SG, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629.