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Volumn 78, Issue 10, 2010, Pages 1033-1040

Urinary granzyme A mRNA is a biomarker to diagnose subclinical and acute cellular rejection in kidney transplant recipients

Author keywords

acute rejection; granzyme A; granzyme B; kidney transplantation; non invasive biomarker; subclinical rejection

Indexed keywords

GRANZYME A; GRANZYME B; MESSENGER RNA; PERFORIN;

EID: 78049479779     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.274     Document Type: Article
Times cited : (30)

References (36)
  • 1
    • 20544476880 scopus 로고    scopus 로고
    • Clinical significance of an early protocol biopsy in living-donor renal transplantation: Ten-year experience at a single center
    • Choi BS, Shin MJ, Shin SJ et al. Clinical significance of an early protocol biopsy in living-donor renal transplantation: ten-year experience at a single center. Am J Transplant 2005; 5: 1354-1360.
    • (2005) Am J Transplant , vol.5 , pp. 1354-1360
    • Choi, B.S.1    Shin, M.J.2    Shin, S.J.3
  • 2
    • 40849119814 scopus 로고    scopus 로고
    • Influence of time of rejection on long-term graft survival in renal transplantation
    • Opelz G, Dohler B. Influence of time of rejection on long-term graft survival in renal transplantation. Transplantation 2008; 85: 661-666.
    • (2008) Transplantation , vol.85 , pp. 661-666
    • Opelz, G.1    Dohler, B.2
  • 3
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograft nephropathy
    • Nankivell BJ, Borrows RJ, Fung CL et al. The natural history of chronic allograft nephropathy. N Engl J Med 2003; 349: 2326-2333.
    • (2003) N Engl J Med , vol.349 , pp. 2326-2333
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 4
    • 3943050053 scopus 로고    scopus 로고
    • Natural history, risk factors, and impact of subclinical rejection in kidney transplantation
    • Nankivell BJ, Borrows RJ, Fung CL et al. Natural history, risk factors, and impact of subclinical rejection in kidney transplantation. Transplantation 2004; 78: 242-249.
    • (2004) Transplantation , vol.78 , pp. 242-249
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 5
    • 33644784069 scopus 로고    scopus 로고
    • Subclinical rejection associated with chronic allograft nephropathy in protocol biopsies as a risk factor for late graft loss
    • Moreso F, Ibernon M, Goma M et al. Subclinical rejection associated with chronic allograft nephropathy in protocol biopsies as a risk factor for late graft loss. Am J Transplant 2006; 6: 747-752.
    • (2006) Am J Transplant , vol.6 , pp. 747-752
    • Moreso, F.1    Ibernon, M.2    Goma, M.3
  • 6
    • 0037378011 scopus 로고    scopus 로고
    • The impact of repeated subclinical acute rejection on the progression of chronic allograft nephropathy
    • Shishido S, Asanuma H, Nakai H et al. The impact of repeated subclinical acute rejection on the progression of chronic allograft nephropathy. J Am Soc Nephrol 2003; 14: 1046-1052.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1046-1052
    • Shishido, S.1    Asanuma, H.2    Nakai, H.3
  • 7
    • 33746904087 scopus 로고    scopus 로고
    • Treatment of subclinical rejection diagnosed by protocol biopsy of kidney transplants
    • Kee TY, Chapman JR, O'Connell PJ et al. Treatment of subclinical rejection diagnosed by protocol biopsy of kidney transplants. Transplantation 2006; 82: 36-42.
    • (2006) Transplantation , vol.82 , pp. 36-42
    • Kee, T.Y.1    Chapman, J.R.2    O'Connell, P.J.3
  • 8
    • 0031758130 scopus 로고    scopus 로고
    • Beneficial effects of treatment of early subclinical rejection: A randomized study
    • Rush D, Nickerson P, Gough J et al. Beneficial effects of treatment of early subclinical rejection: a randomized study. J Am Soc Nephrol 1998; 9: 2129-2134.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 2129-2134
    • Rush, D.1    Nickerson, P.2    Gough, J.3
  • 9
    • 35248889377 scopus 로고    scopus 로고
    • Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: A randomized study
    • Rush D, Arlen D, Boucher A et al. Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study. Am J Transplant 2007; 7: 2538-2545.
    • (2007) Am J Transplant , vol.7 , pp. 2538-2545
    • Rush, D.1    Arlen, D.2    Boucher, A.3
  • 10
    • 34548494343 scopus 로고    scopus 로고
    • Protocol biopsies in renal transplantation: Prognostic value of structural monitoring
    • Seron D, Moreso F. Protocol biopsies in renal transplantation: prognostic value of structural monitoring. Kidney Int 2007; 72: 690-697.
    • (2007) Kidney Int , vol.72 , pp. 690-697
    • Seron, D.1    Moreso, F.2
  • 11
    • 33749543747 scopus 로고    scopus 로고
    • Protocol transplant biopsies: Are they really needed?
    • Wilkinson A. Protocol transplant biopsies: are they really needed? Clin J Am Soc Nephrol 2006; 1: 130-137.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 130-137
    • Wilkinson, A.1
  • 12
    • 49249087744 scopus 로고    scopus 로고
    • Noninvasive prediction of organ graft rejection and outcome using gene expression patterns
    • Anglicheau D, Suthanthiran M. Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. Transplantation 2008; 86: 192-199.
    • (2008) Transplantation , vol.86 , pp. 192-199
    • Anglicheau, D.1    Suthanthiran, M.2
  • 13
    • 0028911887 scopus 로고
    • Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection
    • Kummer JA, Wever PC, Kamp AM et al. Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection. Kidney Int 1995; 47: 70-77.
    • (1995) Kidney Int , vol.47 , pp. 70-77
    • Kummer, J.A.1    Wever, P.C.2    Kamp, A.M.3
  • 14
    • 40849097609 scopus 로고    scopus 로고
    • Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function
    • Aquino-Dias EC, Joelsons G, da Silva DM et al. Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function. Kidney Int 2008.
    • (2008) Kidney Int
    • Aquino-Dias, E.C.1    Joelsons, G.2    Da Silva, D.M.3
  • 15
    • 33746873277 scopus 로고    scopus 로고
    • Urinary cytotoxic molecular markers for a noninvasive diagnosis in acute renal transplant rejection
    • Yannaraki M, Rebibou JM, Ducloux D et al. Urinary cytotoxic molecular markers for a noninvasive diagnosis in acute renal transplant rejection. Transpl Int 2006; 19: 759-768.
    • (2006) Transpl Int , vol.19 , pp. 759-768
    • Yannaraki, M.1    Rebibou, J.M.2    Ducloux, D.3
  • 16
    • 0035967217 scopus 로고    scopus 로고
    • Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine
    • Li B, Hartono C, Ding R et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 2001; 344: 947-954.
    • (2001) N Engl J Med , vol.344 , pp. 947-954
    • Li, B.1    Hartono, C.2    Ding, R.3
  • 17
    • 42949098879 scopus 로고    scopus 로고
    • Death by a thousand cuts: Granzyme pathways of programmed cell death
    • Chowdhury D, Lieberman J. Death by a thousand cuts: granzyme pathways of programmed cell death. Annu Rev Immunol 2008; 26: 389-420.
    • (2008) Annu Rev Immunol , vol.26 , pp. 389-420
    • Chowdhury, D.1    Lieberman, J.2
  • 18
    • 61349091649 scopus 로고    scopus 로고
    • Granule-associated serine proteases: Granzymes might not just be killer proteases
    • Froelich CJ, Pardo J, Simon MM. Granule-associated serine proteases: granzymes might not just be killer proteases. Trends Immunol 2009.
    • (2009) Trends Immunol
    • Froelich, C.J.1    Pardo, J.2    Simon, M.M.3
  • 19
    • 55349138368 scopus 로고    scopus 로고
    • Human and mouse granzyme a induce a proinflammatory cytokine response
    • Metkar SS, Menaa C, Pardo J et al. Human and mouse granzyme a induce a proinflammatory cytokine response. Immunity 2008; 29: 720-733.
    • (2008) Immunity , vol.29 , pp. 720-733
    • Metkar, S.S.1    Menaa, C.2    Pardo, J.3
  • 20
    • 55349109664 scopus 로고    scopus 로고
    • A renaissance in understanding the multiple and diverse functions of granzymes?
    • Trapani JA, Bird PI. A renaissance in understanding the multiple and diverse functions of granzymes? Immunity 2008; 29: 665-667.
    • (2008) Immunity , vol.29 , pp. 665-667
    • Trapani, J.A.1    Bird, P.I.2
  • 21
    • 4644372395 scopus 로고    scopus 로고
    • Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: A potential mechanism for stable renal function in patients with subclinical rejection
    • Rowshani AT, Florquin S, Bemelman F et al. Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: a potential mechanism for stable renal function in patients with subclinical rejection. Kidney Int 2004; 66: 1417-1422.
    • (2004) Kidney Int , vol.66 , pp. 1417-1422
    • Rowshani, A.T.1    Florquin, S.2    Bemelman, F.3
  • 22
    • 0038350649 scopus 로고    scopus 로고
    • Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection
    • Dadhania D, Muthukumar T, Ding R et al. Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection. Transplantation 2003; 75: 1752-1754.
    • (2003) Transplantation , vol.75 , pp. 1752-1754
    • Dadhania, D.1    Muthukumar, T.2    Ding, R.3
  • 23
    • 0038586415 scopus 로고    scopus 로고
    • Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts
    • Muthukumar T, Ding R, Dadhania D et al. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation 2003; 75: 1565-1570.
    • (2003) Transplantation , vol.75 , pp. 1565-1570
    • Muthukumar, T.1    Ding, R.2    Dadhania, D.3
  • 24
    • 0028049383 scopus 로고
    • Histological findings in early routine biopsies of stable renal allograft recipients
    • Rush DN, Henry SF, Jeffery JR et al. Histological findings in early routine biopsies of stable renal allograft recipients. Transplantation 1994; 57: 208-211.
    • (1994) Transplantation , vol.57 , pp. 208-211
    • Rush, D.N.1    Henry, S.F.2    Jeffery, J.R.3
  • 25
    • 66249122732 scopus 로고    scopus 로고
    • Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis
    • Schaub S, Nickerson P, Rush D et al. Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis. Am J Transplant 2009; 9: 1347-1353.
    • (2009) Am J Transplant , vol.9 , pp. 1347-1353
    • Schaub, S.1    Nickerson, P.2    Rush, D.3
  • 26
    • 34447642181 scopus 로고    scopus 로고
    • Detection of subclinical tubular injury after renal transplantation: Comparison of urine protein analysis with allograft histopathology
    • Schaub S, Mayr M, Honger G et al. Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology. Transplantation 2007; 84: 104-112.
    • (2007) Transplantation , vol.84 , pp. 104-112
    • Schaub, S.1    Mayr, M.2    Honger, G.3
  • 27
    • 52649094404 scopus 로고    scopus 로고
    • Prediction of subclinical renal allograft rejection by vascular endothelial growth factor in serum and urine
    • Peng W, Chen J, Jiang Y et al. Prediction of subclinical renal allograft rejection by vascular endothelial growth factor in serum and urine. J Nephrol 2008; 21: 535-542.
    • (2008) J Nephrol , vol.21 , pp. 535-542
    • Peng, W.1    Chen, J.2    Jiang, Y.3
  • 28
    • 33646508545 scopus 로고    scopus 로고
    • Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short-and long-term graft function
    • Matz M, Beyer J, Wunsch D et al. Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short-and long-term graft function. Kidney Int 2006; 69: 1683-1690.
    • (2006) Kidney Int , vol.69 , pp. 1683-1690
    • Matz, M.1    Beyer, J.2    Wunsch, D.3
  • 29
    • 34147163526 scopus 로고    scopus 로고
    • Diagnosis of acute renal allograft rejection by analyzing whole blood mRNA expression of lymphocyte marker molecules
    • Alakulppi NS, Kyllonen LE, Partanen J et al. Diagnosis of acute renal allograft rejection by analyzing whole blood mRNA expression of lymphocyte marker molecules. Transplantation 2007; 83: 791-798.
    • (2007) Transplantation , vol.83 , pp. 791-798
    • Alakulppi, N.S.1    Kyllonen, L.E.2    Partanen, J.3
  • 30
    • 0042362188 scopus 로고    scopus 로고
    • Serial peripheral blood perforin and granzyme B gene expression measurements for prediction of acute rejection in kidney graft recipients
    • Simon T, Opelz G, Wiesel M et al. Serial peripheral blood perforin and granzyme B gene expression measurements for prediction of acute rejection in kidney graft recipients. Am J Transplant 2003; 3: 1121-1127.
    • (2003) Am J Transplant , vol.3 , pp. 1121-1127
    • Simon, T.1    Opelz, G.2    Wiesel, M.3
  • 31
    • 58149260267 scopus 로고    scopus 로고
    • The cytolytic enzymes granyzme A, granzyme B, and perforin: Expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression
    • Chattopadhyay PK, Betts MR, Price DA et al. The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression. J Leukoc Biol 2009; 85: 88-97.
    • (2009) J Leukoc Biol , vol.85 , pp. 88-97
    • Chattopadhyay, P.K.1    Betts, M.R.2    Price, D.A.3
  • 32
    • 33745113482 scopus 로고    scopus 로고
    • Human virus-specific CD8+ T cells: Diversity specialists
    • van Leeuwen EM, de Bree GJ, ten Berge IJM et al. Human virus-specific CD8+ T cells: diversity specialists. Immunol Rev 2006; 211: 225-235.
    • (2006) Immunol Rev , vol.211 , pp. 225-235
    • Van Leeuwen, E.M.1    De Bree, G.J.2    Ten Berge, I.J.M.3
  • 33
    • 27944510520 scopus 로고    scopus 로고
    • The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation
    • Rowshani AT, Strik MC, Molenaar R et al. The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation. J Infect Dis 2005; 192: 1908-1911.
    • (2005) J Infect Dis , vol.192 , pp. 1908-1911
    • Rowshani, A.T.1    Strik, M.C.2    Molenaar, R.3
  • 34
    • 33847761900 scopus 로고    scopus 로고
    • Banff '05 Meeting Report: Differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN')
    • Solez K, Colvin RB, Racusen LC et al. Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant 2007; 7: 518-526.
    • (2007) Am J Transplant , vol.7 , pp. 518-526
    • Solez, K.1    Colvin, R.B.2    Racusen, L.C.3
  • 35
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 36
    • 29744469415 scopus 로고    scopus 로고
    • Recommendations for improving serum creatinine measurement: A report from the Laboratory Working Group of the National Kidney Disease Education Program
    • Myers GL, Miller WG, Coresh J et al. Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem 2006; 52: 5-18.
    • (2006) Clin Chem , vol.52 , pp. 5-18
    • Myers, G.L.1    Miller, W.G.2    Coresh, J.3


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