Polyomavirus nephropathy: Quantitative urinary polyomavirus-haufen testing accurately predicts the degree of intrarenal viral disease

Transplantation

Volumn 99, Issue 3, 2015, Pages 609-615

  Singh, Harsharan K ^a   Reisner, Howard ^a   Derebail, Vimal K ^a   Kozlowski, Tomasz ^a   Nickeleit, Volker ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; SV40 T ANTIGEN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS T ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERMETHOD COMPARISON; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY DISEASE; LABORATORY TEST; POLYMERASE CHAIN REACTION; POLYOMAVIRUS NEPHROPATHY; POLYOMAVIRUS NEPHROPATHY HAUFEN TEST; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIMIAN VIRUS 40; URINALYSIS; VIRUS REPLICATION; BIOPSY; CHEMISTRY; GRAFT SURVIVAL; KIDNEY DISEASES; PHYSIOLOGY; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; REPRODUCIBILITY; URINE; VIREMIA; VIROLOGY;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; BIOPSY; DNA, VIRAL; GRAFT SURVIVAL; HUMANS; KIDNEY DISEASES; POLYMERASE CHAIN REACTION; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; REPRODUCIBILITY OF RESULTS; VIREMIA; VIRUS REPLICATION;

EID: 84942835191     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000367     Document Type: Article

References (36)

1. Benavides CA, Pollard VB, Mauiyyedi S, BK virus-associated nephropathy in sirolimus-treated renal transplant patients: incidence, course, and clinical outcomes. Transplantation 2007; 84: 83
2. Hirsch HH, Randhawa P,. BK polyomavirus in solid organ transplantation. Am J Transplant 2013; 13 (Suppl 4): 179
3. van Aalderen MC, Heutinck KM, Huisman C, BK virus infection in transplant recipients: clinical manifestations, treatment options and the immune response. Neth J Med 2012; 70: 172
4. Ranzi AD, Prolla JC, Keitel E, The role of urine cytology for 'decoy cells as a screening tool in renal transplant recipients. Acta Cytol 2012; 56: 543
5. Sharif A, Alachkar N, Bagnasco S, Incidence and outcomes of BK virus allograft nephropathy among ABO- and HLA-incompatible kidney transplant recipients. Clin J Am Soc Nephrol 2012; 7: 1320
6. Nickeleit V,. The Pathology of Kidney Transplantation. In: Ruiz P, ed. Transplantation Pathology. 1st ed. New York, NY: Cambridge University Press; 2009: 83
7. Colvin RB, Nickeleit V,. Renal Transplant Pathology. In: Jennette JC, Olson JL, Schwartz MM, eds. Heptinstall's Pathology of the Kidney. 6th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2007: 1441
8. Nickeleit V, Mihatsch MJ,. Polyomavirus nephropathy in native kidneys and renal allografts: an update on an escalating threat. Transpl Int 2006; 19: 960
9. Hirsch HH, Babel N, Comoli P, European perspective on human polyomavirus infection, replication and disease in solid organ transplantation. Clin Microbiol Infect 2014; 20 (Suppl 7): 74
10. Chakera A, Dyar OJ, Hughes E, Detection of polyomavirus BK reactivation after renal transplantation using an intensive decoy cell surveillance program is cost-effective. Transplantation 2011; 92: 1018
11. Singh HK, Bubendorf L, Mihatsch MJ, Urine cytology findings of polyomavirus infections. In: Ahsan N, ed. Polyomaviruses and Human Diseases. 1st ed. Georgetown, TX: Springer Science+Business Media, Landes Bioscience/Eurekah.com; 2006: 201
12. Nickeleit V, Steiger J, Mihatsch MJ,. Re: noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1. Transplantation 2003; 75: 2160
13. Nickeleit V, Klimkait T, Binet IF, Testing for polyomavirus type BK DNA in plasma to identify renal-allograft recipients with viral nephropathy. N Engl J Med 2000; 342: 1309
14. Hirsch HH, Drachenberg CB, Steiger J, Polyomavirus associated nephropathy in renal transplantation: critical issues of screening and management. In: Ahsan N, ed. Polyomaviruses and Human Diseases. 1st ed. New York, NY: Springer Science+Business Media, Landes Bioscience /Eurekah.com; 2006: 160
15. Randhawa P, Ho A, Shapiro R, Correlates of quantitative measurement of BK polyomavirus (BKV) DNA with clinical course of BKV infection in renal transplant patients. J Clin Microbiol 2004; 42: 1176
16. Thamboo TP, Jeffery KJ, Friend PJ, Urine cytology screening for polyoma virus infection following renal transplantation: the Oxford experience. J Clin Pathol 2007; 60: 927
17. Hirsch HH, Brennan DC, Drachenberg CB, Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 2005; 79: 1277
18. Hirsch HH, Knowles W, Dickenmann M, Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med 2002; 347: 488
19. Nickeleit V, True K, Detwiler R, Risk assessment for polyomavirus nephropathy using urine cytology and the detection of decoy cells: cheap and efficient. Transplantation 2012; 94: e42
20. Singh H, Andreoni KA, Madden V, Presence of urinary Haufen accurately predicts polyomavirus nephropathy. J Am Soc Nephrol 2009; 20: 416
21. Hirsch HH,. Polyomavirus BK nephropathy: a (re-)emerging complication in renal transplantation. Am J Transplant 2002; 2: 25
22. Grinde B,. Herpesviruses: latency and reactivation-viral strategies and host response. J Oral Microbiol 2013; 5
23. Fishman JA,. Overview: cytomegalovirus and the herpesviruses in transplantation. Am J Transplant 2013; 13 (Suppl 3): 1
24. Egli A, Binggeli S, Bodaghi S, Cytomegalovirus and polyomavirus BK posttransplant. Nephrol Dial Transplant 2007; 22 (Suppl 8): viii72
25. Burger-Calderon R, Madden V, Hallett RA, Replication of oral BK virus in human salivary gland cells. J Virol 2014; 88: 559
26. Jeffers LK, Madden V, Webster-Cyriaque J,. BK virus has tropism for human salivary gland cells in vitro: implications for transmission. Virology 2009; 394: 183
27. Jeffers L, Webster-Cyriaque JY,. Viruses and salivary gland disease (SGD): lessons from HIV SGD. Adv Dent Res 2011; 23: 79
28. Erard V, Kim HW, Corey L, BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood 2005; 106: 1130
29. Singh HK, Donna Thompson B, Nickeleit V,. Viral Haufen are urinary biomarkers of polyomavirus nephropathy: new diagnostic strategies utilizing negative staining electron microscopy. Ultrastruct Pathol 2009; 33: 222
30. Nickeleit V, Brylawski B, Rivier L, Urinary polyomavirus-Haufen shedding in mouse and man: a proof-of-concept study for a non-invasive urine biomarker for polyomavirus nephropathy. Lab Invest 2013; 93: 390A
31. Haas M, Sis B, Racusen LC, Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions. Am J Transplant 2014; 14: 272
32. Tamm I, Bugher JC, Horsfall FL,. Ultracentrifugation studies of a urinary mucoprotein which reacts with various viruses. J Biol Chem 1955; 212: 125
33. Hayat MA, Miller SE,. Negative Staining. New York, NY: McGraw-Hill Publishing Company; 1990
34. Racusen LC, Solez K, Colvin RB, The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713
35. Nickeleit V, Hirsch HH, Binet IF, Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease. J Am Soc Nephrol 1999; 10: 1080
36. Miller SE,. Virus particle counting by electron microscopy. In: Griffith J, ed. Electron Microscopy in Biology. New York, NY: Wiley; 1982: 306