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Volumn 429, Issue 21, 2017, Pages 3132-3138

Canonical DNA Repair Pathways Influence R-Loop-Driven Genome Instability

Author keywords

DNA repair; Fanconi Anemia; Fork protection; Genome Instability; R loops

Indexed keywords

DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; MALIGNANT NEOPLASM; MUTAGENESIS; NONHUMAN; NUCLEIC ACID STRUCTURE; ONCOGENE; PRIORITY JOURNAL; R LOOP; REVIEW; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; CONFORMATION; DNA REPLICATION; GENETIC TRANSCRIPTION; GENETICS;

EID: 84979753506     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2016.07.014     Document Type: Review
Times cited : (37)

References (46)
  • 2
    • 21744452376 scopus 로고    scopus 로고
    • Cancer in xeroderma pigmentosum and related disorders of DNA repair
    • Cleaver, J.E., Cancer in xeroderma pigmentosum and related disorders of DNA repair. Nat. Rev. Cancer 5 (2005), 564–573.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 564-573
    • Cleaver, J.E.1
  • 3
    • 34247164462 scopus 로고    scopus 로고
    • Involvement of homologous recombination in carcinogenesis
    • Reliene, R., Bishop, A.J., Schiestl, R.H., Involvement of homologous recombination in carcinogenesis. Adv. Genet. 58 (2007), 67–87.
    • (2007) Adv. Genet. , vol.58 , pp. 67-87
    • Reliene, R.1    Bishop, A.J.2    Schiestl, R.H.3
  • 4
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • Garraway, L.A., Lander, E.S., Lessons from the cancer genome. Cell 153 (2013), 17–37.
    • (2013) Cell , vol.153 , pp. 17-37
    • Garraway, L.A.1    Lander, E.S.2
  • 5
    • 46249131123 scopus 로고    scopus 로고
    • Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
    • Bennardo, N., Cheng, A., Huang, N., Stark, J.M., Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet., 4, 2008, e1000110.
    • (2008) PLoS Genet. , vol.4
    • Bennardo, N.1    Cheng, A.2    Huang, N.3    Stark, J.M.4
  • 7
    • 79954505570 scopus 로고    scopus 로고
    • SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis
    • Lin, J.R., Zeman, M.K., Chen, J.Y., Yee, M.C., Cimprich, K.A., SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis. Mol. Cell 42 (2011), 237–249.
    • (2011) Mol. Cell , vol.42 , pp. 237-249
    • Lin, J.R.1    Zeman, M.K.2    Chen, J.Y.3    Yee, M.C.4    Cimprich, K.A.5
  • 8
    • 84860338675 scopus 로고    scopus 로고
    • R loops: from transcription byproducts to threats to genome stability
    • Aguilera, A., Garcia-Muse, T., R loops: from transcription byproducts to threats to genome stability. Mol. Cell 46 (2012), 115–124.
    • (2012) Mol. Cell , vol.46 , pp. 115-124
    • Aguilera, A.1    Garcia-Muse, T.2
  • 9
    • 84901474570 scopus 로고    scopus 로고
    • Mechanisms of genome instability induced by RNA-processing defects
    • Chan, Y.A., Hieter, P., Stirling, P.C., Mechanisms of genome instability induced by RNA-processing defects. Trends Genet. 30 (2014), 245–253.
    • (2014) Trends Genet. , vol.30 , pp. 245-253
    • Chan, Y.A.1    Hieter, P.2    Stirling, P.C.3
  • 10
    • 61349102407 scopus 로고    scopus 로고
    • Ribonuclease H: the enzymes in eukaryotes
    • Cerritelli, S.M., Crouch, R.J., Ribonuclease H: the enzymes in eukaryotes. FEBS J. 276 (2009), 1494–1505.
    • (2009) FEBS J. , vol.276 , pp. 1494-1505
    • Cerritelli, S.M.1    Crouch, R.J.2
  • 12
    • 23744455164 scopus 로고    scopus 로고
    • Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
    • Li, X., Manley, J.L., Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 122 (2005), 365–378.
    • (2005) Cell , vol.122 , pp. 365-378
    • Li, X.1    Manley, J.L.2
  • 15
    • 84887604599 scopus 로고    scopus 로고
    • The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability
    • Santos-Pereira, J.M., Herrero, A.B., Garcia-Rubio, M.L., Marin, A., Moreno, S., Aguilera, A., The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability. Genes Dev. 27 (2013), 2445–2458.
    • (2013) Genes Dev. , vol.27 , pp. 2445-2458
    • Santos-Pereira, J.M.1    Herrero, A.B.2    Garcia-Rubio, M.L.3    Marin, A.4    Moreno, S.5    Aguilera, A.6
  • 17
    • 84885081625 scopus 로고    scopus 로고
    • GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination
    • Ginno, P.A., Lim, Y.W., Lott, P.L., Korf, I.F., Chedin, F., GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination. Genome Res., 2013, 1590–1600.
    • (2013) Genome Res. , pp. 1590-1600
    • Ginno, P.A.1    Lim, Y.W.2    Lott, P.L.3    Korf, I.F.4    Chedin, F.5
  • 18
    • 73649101345 scopus 로고    scopus 로고
    • Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site
    • Roy, D., Zhang, Z., Lu, Z., Hsieh, C.L., Lieber, M.R., Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site. Mol. Cell. Biol. 30 (2010), 146–159.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 146-159
    • Roy, D.1    Zhang, Z.2    Lu, Z.3    Hsieh, C.L.4    Lieber, M.R.5
  • 25
    • 84918791689 scopus 로고    scopus 로고
    • Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability
    • Sollier, J., Stork, C.T., Garcia-Rubio, M.L., Paulsen, R.D., Aguilera, A., Cimprich, K.A., Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability. Mol. Cell 56 (2014), 777–785.
    • (2014) Mol. Cell , vol.56 , pp. 777-785
    • Sollier, J.1    Stork, C.T.2    Garcia-Rubio, M.L.3    Paulsen, R.D.4    Aguilera, A.5    Cimprich, K.A.6
  • 26
    • 0034604622 scopus 로고    scopus 로고
    • Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro
    • Tian, M., Alt, F.W., Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro. J. Biol. Chem. 275 (2000), 24,163–24,172.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24163-24172
    • Tian, M.1    Alt, F.W.2
  • 27
  • 28
    • 84963657302 scopus 로고    scopus 로고
    • Interplay between Fanconi anemia and homologous recombination pathways in genome integrity
    • Michl, J., Zimmer, J., Tarsounas, M., Interplay between Fanconi anemia and homologous recombination pathways in genome integrity. EMBO J. 35 (2016), 909–923.
    • (2016) EMBO J. , vol.35 , pp. 909-923
    • Michl, J.1    Zimmer, J.2    Tarsounas, M.3
  • 30
    • 0034031137 scopus 로고    scopus 로고
    • DNA double strand break repair in mammalian cells
    • Karran, P., DNA double strand break repair in mammalian cells. Curr. Opin. Genet. Dev. 10 (2000), 144–150.
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 144-150
    • Karran, P.1
  • 31
    • 84863753191 scopus 로고    scopus 로고
    • A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2
    • Schlacher, K., Wu, H., Jasin, M., A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell 22 (2012), 106–116.
    • (2012) Cancer Cell , vol.22 , pp. 106-116
    • Schlacher, K.1    Wu, H.2    Jasin, M.3
  • 35
    • 84901984431 scopus 로고    scopus 로고
    • The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder
    • Walden, H., Deans, A.J., The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder. Annu. Rev. Biophys. 43 (2014), 257–278.
    • (2014) Annu. Rev. Biophys. , vol.43 , pp. 257-278
    • Walden, H.1    Deans, A.J.2
  • 40
  • 41
    • 84879062475 scopus 로고    scopus 로고
    • The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability
    • Wahba, L., Gore, S.K., Koshland, D., The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability. eLife, 2, 2013, e00505.
    • (2013) eLife , vol.2
    • Wahba, L.1    Gore, S.K.2    Koshland, D.3
  • 42
    • 84958623054 scopus 로고    scopus 로고
    • RNA processing and genome stability: cause and consequence
    • Wickramasinghe, V.O., Venkitaraman, A.R., RNA processing and genome stability: cause and consequence. Mol. Cell 61 (2016), 496–505.
    • (2016) Mol. Cell , vol.61 , pp. 496-505
    • Wickramasinghe, V.O.1    Venkitaraman, A.R.2
  • 44
    • 84859087611 scopus 로고    scopus 로고
    • R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters
    • Ginno, P.A., Lott, P.L., Christensen, H.C., Korf, I., Chedin, F., R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters. Mol. Cell 45 (2012), 814–825.
    • (2012) Mol. Cell , vol.45 , pp. 814-825
    • Ginno, P.A.1    Lott, P.L.2    Christensen, H.C.3    Korf, I.4    Chedin, F.5
  • 45
    • 84255177502 scopus 로고    scopus 로고
    • RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability
    • Wahba, L., Amon, J.D., Koshland, D., Vuica-Ross, M., RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. Mol. Cell 44 (2011), 978–988.
    • (2011) Mol. Cell , vol.44 , pp. 978-988
    • Wahba, L.1    Amon, J.D.2    Koshland, D.3    Vuica-Ross, M.4
  • 46
    • 77954841539 scopus 로고    scopus 로고
    • Loss of topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis
    • El Hage, A., French, S.L., Beyer, A.L., Tollervey, D., Loss of topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev. 24 (2010), 1546–1558.
    • (2010) Genes Dev. , vol.24 , pp. 1546-1558
    • El Hage, A.1    French, S.L.2    Beyer, A.L.3    Tollervey, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.