Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Genes and Development

Volumn 30, Issue 3, 2016, Pages 337-354

  Poli, Jérôme ^a   Gerhold, Christian Benedikt ^a   Tosi, Alessandro ^b   Hustedt, Nicole ^a,e   Seeber, Andrew ^a   Sack, Ragna ^a   Herzog, Franz ^b   Pasero, Philippe ^c   Shimada, Kenji ^a   Hopfner, Karl Peter ^b   Gasser, Susan M ^a,d  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF HUMAN GENETICS   (France)

^d UNIVERSITY OF BASEL   (Switzerland)

^e MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Checkpoint; Genome instability; INO80; Replication stress; RNAPII; Transcription replication interference

Indexed keywords

HYDROXYUREA; RNA POLYMERASE II; INO80 COMPLEX, S CEREVISIAE; MEC1 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; PAF1 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DDC2 GENE; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DNA TRANSCRIPTION; GENE; GENE INTERACTION; GENOMIC INSTABILITY; IMMUNOPRECIPITATION; INO80 GENE; MEC1 GENE; NONHUMAN; PAF1 GENE; PRIORITY JOURNAL; RNA DEGRADATION; RNA INTERFERENCE; TRANSCRIPTION ELONGATION; ULTRAVIOLET RADIATION; YEAST; YEAST CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGICAL STRESS; SACCHAROMYCES CEREVISIAE;

DNA REPLICATION; GENE EXPRESSION REGULATION, FUNGAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL;

EID: 84957805308     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.273813.115     Document Type: Article

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