Overexpression of miR-223 tips the balance of pro- and anti-hypertrophic signaling cascades toward physiologic cardiac hypertrophy

Journal of Biological Chemistry

Volumn 291, Issue 30, 2016, Pages 15700-15713

  Yang, Liwang ^a,b   Li, Yutian ^b   Wang, Xiaohong ^b   Mu, Xingjiang ^b   Qin, Dongze ^a,b   Huang, Wei ^b   Alshahrani, Saeed ^b   Nieman, Michelle ^b   Peng, Jiangtong ^b,c   Essandoh, Kobina ^b   Peng, Tianqing ^d   Wang, Yigang ^b   Lorenz, John ^b   Soleimani, Manoocher ^b   Zhao, Zhi Qing ^a   Fan, Guo Chang ^b  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HEART; PATHOLOGY; PHYSIOLOGY; PLANTS (BOTANY); SIGNALING;

CARDIAC FUNCTIONS; CARDIAC HYPERTROPHY; NEGATIVE REGULATORS; NEONATAL RAT CARDIOMYOCYTES; SIGNALING CASCADES; SIGNALING PATHWAYS; SPECIFIC INHIBITORS; WESTERN BLOTTING;

RNA;

8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ACTIVIN A RECEPTOR TYPE II A; ACTIVIN RECEPTOR; BETA1 INTEGRIN; FBXW7 PROTEIN; MICRORNA 223; PROTEIN KINASE B; SOMATOMEDIN C RECEPTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR TYPE II-A; F BOX PROTEIN; FBXW7 PROTEIN, MOUSE; MICRORNA; MIRN223 MICRORNA, MOUSE; MIRN223 MICRORNA, RAT; UBIQUITIN PROTEIN LIGASE;

3' UNTRANSLATED REGION; AKIP1 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATF3 GENE; ATF5 GENE; CELL GROWTH; CONTROLLED STUDY; COPY NUMBER VARIATION; EGLN3 GENE; EGR1 GENE; GENE; GENE INACTIVATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC SCREENING; GENOTYPING TECHNIQUE; HEART FUNCTION; HEART HYPERTROPHY; HEART MUSCLE FIBROSIS; ITGB1 GENE; MALE; MOUSE; NDRG4 GENE; NEWBORN; NEXT GENERATION SEQUENCING; NONHUMAN; POSTN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; RNA SEQUENCE; RXFP1 GENE; SFRP2 GENE; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WESTERN BLOTTING; ADENOVIRIDAE; ANIMAL; BIOSYNTHESIS; CARDIOMEGALY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; METABOLISM; PATHOLOGY;

ACTIVIN RECEPTORS, TYPE II; ADENOVIRIDAE; ANIMALS; CARDIOMEGALY; DISEASE MODELS, ANIMAL; F-BOX PROTEINS; GENE EXPRESSION REGULATION; MICE; MICE, TRANSGENIC; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC; UBIQUITIN-PROTEIN LIGASES;

EID: 84979017658     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.715805     Document Type: Article

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