메뉴 건너뛰기




Volumn 309, Issue 4, 2015, Pages H543-H552

Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs

Author keywords

Angiogenesis; Cardiac hypertrophy; MicroRNA; Running training; Swimming training

Indexed keywords

COLLAGEN TYPE 2; MICRORNA; MICRORNA 1; MICRORNA 103; MICRORNA 126; MICRORNA 130A; MICRORNA 133; MICRORNA 143; MICRORNA 145; MICRORNA 146A; MICRORNA 195; MICRORNA 199A; MICRORNA 199B; MICRORNA 208; MICRORNA 21; MICRORNA 210; MICRORNA 221; MICRORNA 222; MICRORNA 26; MICRORNA 27A; MICRORNA 27B; MICRORNA 34A; MICRORNA 34B; MICRORNA 378; MICRORNA 497; MICRORNA 499; MICRORNA 9; MICRORNA 98; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN;

EID: 84939431521     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00899.2014     Document Type: Review
Times cited : (118)

References (102)
  • 1
    • 84908430807 scopus 로고    scopus 로고
    • Resistance training improves hemodynamic function, collagen deposition and inflammatory profiles: Experimental model of heart failure
    • Alves JP, Nunes RB, Stefani GP, Dal Lago P. Resistance training improves hemodynamic function, collagen deposition and inflammatory profiles: experimental model of heart failure. PLoS One 9: e110317, 2014.
    • (2014) Plos One , vol.9
    • Alves, J.P.1    Nunes, R.B.2    Stefani, G.P.3    Dal Lago, P.4
  • 4
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 5
    • 78650121847 scopus 로고    scopus 로고
    • Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
    • Bernardo BC, Weeks KL, Pretorius L, McMullen JR. Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. Pharmacol Ther 128: 191-227, 2010.
    • (2010) Pharmacol Ther , vol.128 , pp. 191-227
    • Bernardo, B.C.1    Weeks, K.L.2    Pretorius, L.3    McMullen, J.R.4
  • 6
    • 0033968828 scopus 로고    scopus 로고
    • Waging war on modern chronic diseases: Primary prevention through exercise biology
    • Booth FW, Gordon SE, Carlson CJ, Hamilton MT. Waging war on modern chronic diseases: primary prevention through exercise biology. J Appl Physiol 88: 774-787, 2000.
    • (2000) J Appl Physiol , vol.88 , pp. 774-787
    • Booth, F.W.1    Gordon, S.E.2    Carlson, C.J.3    Hamilton, M.T.4
  • 7
    • 84884136022 scopus 로고    scopus 로고
    • Impact of exercise training on redox signaling in cardiovascular diseases
    • Campos JC, Gomes KM, Ferreira JCB. Impact of exercise training on redox signaling in cardiovascular diseases. Food Chem Toxicol 62: 107-19, 2013.
    • (2013) Food Chem Toxicol , vol.62 , pp. 107-119
    • Campos, J.C.1    Gomes, K.M.2    Ferreira, J.3
  • 9
    • 84877616567 scopus 로고    scopus 로고
    • Potential therapeutic role of microRNAs in ischemic heart disease
    • Caroli A, Cardillo MT, Galea R, Biasucci LM. Potential therapeutic role of microRNAs in ischemic heart disease. J Cardiol 61: 315-320, 2013.
    • (2013) J Cardiol , vol.61 , pp. 315-320
    • Caroli, A.1    Cardillo, M.T.2    Galea, R.3    Biasucci, L.M.4
  • 12
    • 34447318648 scopus 로고    scopus 로고
    • MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy
    • Cheng Y, Ji R, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol 170: 1831-1840, 2007.
    • (2007) Am J Pathol , vol.170 , pp. 1831-1840
    • Cheng, Y.1    Ji, R.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 17
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Aktdependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Aktdependent phosphorylation. Nature 399: 601-605, 1999.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 18
    • 34247877577 scopus 로고    scopus 로고
    • The fuzzy logic of physiological cardiac hypertrophy
    • Dorn GW. The fuzzy logic of physiological cardiac hypertrophy. Hypertension 49: 962-970, 2007.
    • (2007) Hypertension , vol.49 , pp. 962-970
    • Dorn, G.W.1
  • 19
    • 73449086958 scopus 로고    scopus 로고
    • Reciprocal regulation of microrna-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions
    • Elia L, Contu R, Quintavalle M, Varrone F, Chimenti C, Russo MA, Cimino V, De Marinis L, Frustaci A, Catalucci D, Condorelli G. Reciprocal regulation of microrna-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation 120: 2377-2385, 2009.
    • (2009) Circulation , vol.120 , pp. 2377-2385
    • Elia, L.1    Contu, R.2    Quintavalle, M.3    Varrone, F.4    Chimenti, C.5    Russo, M.A.6    Cimino, V.7    De Marinis, L.8    Frustaci, A.9    Catalucci, D.10    Condorelli, G.11
  • 20
    • 84155160706 scopus 로고    scopus 로고
    • Physiological cardiac remodelling in response to endurance exercise training: Cellular and molecular mechanisms
    • Ellison GM, Waring CD, Vicinanza C, Torella D. Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms. Heart 98: 5-10, 2012.
    • (2012) Heart , vol.98 , pp. 5-10
    • Ellison, G.M.1    Waring, C.D.2    Vicinanza, C.3    Torella, D.4
  • 21
    • 80051473367 scopus 로고    scopus 로고
    • Aerobic exercise training-induced left ventricular hypertrophy involves regulatory MicroRNAs, decreased angiotensin-converting enzyme-angiotensin II, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1-7)
    • Fernandes T, Hashimoto NY, Magalhães FC, Fernandes FB, Casarini DE, Carmona AK, Krieger JE, Phillips MI, Oliveira EM. Aerobic exercise training-induced left ventricular hypertrophy involves regulatory MicroRNAs, decreased angiotensin-converting enzyme-angiotensin II, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1-7). Hypertension 58: 182-189, 2011.
    • (2011) Hypertension , vol.58 , pp. 182-189
    • Fernandes, T.1    Hashimoto, N.Y.2    Magalhães, F.C.3    Fernandes, F.B.4    Casarini, D.E.5    Carmona, A.K.6    Krieger, J.E.7    Phillips, M.I.8    Oliveira, E.M.9
  • 22
    • 84856078602 scopus 로고    scopus 로고
    • Exercise training prevents the microvascular rarefaction in hypertension balancing angiogenic and apoptotic factors: Role of microRNAs-16, -21, and -126
    • Fernandes T, Magalhães FC, Roque FR, Phillips MI, Oliveira EM. Exercise training prevents the microvascular rarefaction in hypertension balancing angiogenic and apoptotic factors: role of microRNAs-16, -21, and -126. Hypertension 59: 513-520, 2012.
    • (2012) Hypertension , vol.59 , pp. 513-520
    • Fernandes, T.1    Magalhães, F.C.2    Roque, F.R.3    Phillips, M.I.4    Oliveira, E.M.5
  • 24
    • 80053331731 scopus 로고    scopus 로고
    • Eccentric and concentric cardiac hypertrophy induced by exercise training: MicroRNAs and molecular determinants
    • Fernandes T, Soci UP, Oliveira EM. Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants. Braz J Med Biol Res 44: 836-847, 2011.
    • (2011) Braz J Med Biol Res , vol.44 , pp. 836-847
    • Fernandes, T.1    Soci, U.P.2    Oliveira, E.M.3
  • 25
    • 84939449431 scopus 로고    scopus 로고
    • MiRNA-208a targeting Purßgene regulates the ß-MHC content in cardiac hypertrophy induced by exercise training
    • Fernandes T, Soci UP, Oliveira EM. MiRNA-208a targeting Purßgene regulates the ß-MHC content in cardiac hypertrophy induced by exercise training. Circ Res 128: A21942, 2013.
    • (2013) Circ Res , vol.128
    • Fernandes, T.1    Soci, U.P.2    Oliveira, E.M.3
  • 27
    • 84891633821 scopus 로고    scopus 로고
    • Resistance exercise acutely enhances mesenteric artery insulininduced relaxation in healthy rats
    • Fontes MT, Silva TL, Mota MM, Barreto AS, Rossoni LV, Santos MR. Resistance exercise acutely enhances mesenteric artery insulininduced relaxation in healthy rats. Life Sci 94: 24-29, 2014.
    • (2014) Life Sci , vol.94 , pp. 24-29
    • Fontes, M.T.1    Silva, T.L.2    Mota, M.M.3    Barreto, A.S.4    Rossoni, L.V.5    Santos, M.R.6
  • 28
    • 79958157766 scopus 로고    scopus 로고
    • Recent advances in preventive cardiology and lifestyle medicine: A themed series
    • Franklin BA, Cushman M. Recent advances in preventive cardiology and lifestyle medicine: a themed series. Circulation 123: 2274-2283, 2011.
    • (2011) Circulation , vol.123 , pp. 2274-2283
    • Franklin, B.A.1    Cushman, M.2
  • 29
    • 73449114573 scopus 로고    scopus 로고
    • Exercise and the growth hormone-insulin-like growth factor axis
    • Frystyk J. Exercise and the growth hormone-insulin-like growth factor axis. Med Sci Sports Exerc 42: 58-66, 2010.
    • (2010) Med Sci Sports Exerc , vol.42 , pp. 58-66
    • Frystyk, J.1
  • 30
    • 80054739223 scopus 로고    scopus 로고
    • Left ventricular structural remodeling in health and disease: With special emphasis on volume, mass, and geometry
    • Gaasch WH, Zile MR. Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometry. J Am Coll Cardiol 58: 1733-40, 2011.
    • (2011) J am Coll Cardiol , vol.58 , pp. 1733-1740
    • Gaasch, W.H.1    Zile, M.R.2
  • 31
    • 79959902659 scopus 로고    scopus 로고
    • Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise
    • Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43: 1334-1359, 2011.
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1334-1359
    • Garber, C.E.1    Blissmer, B.2    Deschenes, M.R.3    Franklin, B.A.4    Lamonte, M.J.5    Lee, I.M.6    Nieman, D.C.7    Swain, D.P.8
  • 33
    • 84862276451 scopus 로고    scopus 로고
    • Exercise and the cardiovascular system
    • Golbidi S, Laher I. Exercise and the cardiovascular system. Cardiol Res Pract 2012: 210852, 2012.
    • (2012) Cardiol Res Pract , vol.2012
    • Golbidi, S.1    Laher, I.2
  • 34
    • 37849021505 scopus 로고    scopus 로고
    • Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training
    • Gomez-Cabrera MC, Domenech E, Viña J. Moderate exercise is an antioxidant: upregulation of antioxidant genes by training. Free Radic Biol Med 44: 126-131, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 126-131
    • Gomez-Cabrera, M.C.1    Domenech, E.2    Viña, J.3
  • 35
    • 0016681078 scopus 로고
    • Wall stress and patterns of hypertrophy in the human left ventricle
    • Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 56: 56-64, 1975.
    • (1975) J Clin Invest , vol.56 , pp. 56-64
    • Grossman, W.1    Jones, D.2    McLaurin, L.P.3
  • 37
    • 0023665075 scopus 로고
    • Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes
    • Gustafson TA, Bahl JJ, Markham BE, Roeske WR, Morkin E. Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes. J Biol Chem 262: 13316-13322, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 13316-13322
    • Gustafson, T.A.1    Bahl, J.J.2    Markham, B.E.3    Roeske, W.R.4    Morkin, E.5
  • 38
    • 84879671055 scopus 로고    scopus 로고
    • Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs
    • Hangauer MJ, Vaughn IW, McManus MT. Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet 9: e1003569, 2013.
    • (2013) Plos Genet , vol.9
    • Hangauer, M.J.1    Vaughn, I.W.2    McManus, M.T.3
  • 41
    • 34249981756 scopus 로고    scopus 로고
    • A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: The benefit depends on the type of training performed
    • Haykowsky MJ, Liang Y, Pechter D, Jones LW, McAlister FA, Clark AM. A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed. J Am Coll Cardiol 49: 2329-2336, 2007.
    • (2007) J am Coll Cardiol , vol.49 , pp. 2329-2336
    • Haykowsky, M.J.1    Liang, Y.2    Pechter, D.3    Jones, L.W.4    McAlister, F.A.5    Clark, A.M.6
  • 42
    • 0037465434 scopus 로고    scopus 로고
    • Progression from compensated hypertrophy to failure in the pressure-overloaded human: Heart structural deterioration and compensatory mechanisms
    • Hein S, Arnon E, Kostin S, Schönburg M, Elsässer A, Polyakova V, Bauer EP, Klövekorn WP, Schaper J. Progression from compensated hypertrophy to failure in the pressure-overloaded human: heart structural deterioration and compensatory mechanisms. Circulation 107: 984-991, 2003.
    • (2003) Circulation , vol.107 , pp. 984-991
    • Hein, S.1    Arnon, E.2    Kostin, S.3    Schönburg, M.4    Elsässer, A.5    Polyakova, V.6    Bauer, E.P.7    Klövekorn, W.P.8    Schaper, J.9
  • 43
    • 0002801008 scopus 로고
    • Skidlauf und Skidwettlauf. Eine medizinische Sportstudie
    • Henschen S. Skidlauf und Skidwettlauf. Eine medizinische Sportstudie. Mitt Med Klin Upsala 2: 15, 1899.
    • (1899) Mitt Med Klin Upsala , vol.2 , pp. 15
    • Henschen, S.1
  • 46
    • 0023713203 scopus 로고
    • Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload
    • Izumo S, Nadal-Ginard B, Mahdavi V. Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci USA 85: 339-43, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 339-343
    • Izumo, S.1    Nadal-Ginard, B.2    Mahdavi, V.3
  • 48
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 6: 376-385, 2005.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 49
    • 85006221508 scopus 로고    scopus 로고
    • Treating diabetes with exercise—focus on the microvasculature
    • Kolka C. Treating diabetes with exercise—focus on the microvasculature. J Diabetes Metab 4: 308, 2013.
    • (2013) J Diabetes Metab , vol.4 , pp. 308
    • Kolka, C.1
  • 50
    • 84883425232 scopus 로고    scopus 로고
    • Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes
    • Kolwicz SC, Purohit S, Tian R. Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes. Circ Res 113: 603-616, 2013.
    • (2013) Circ Res , vol.113 , pp. 603-616
    • Kolwicz, S.C.1    Purohit, S.2    Tian, R.3
  • 54
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854, 1993
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 55
    • 0033553389 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart
    • Li B, Setoguchi M, Wang X, Andreoli AM, Leri A, Malhotra A, Kajstura J, Anversa P. Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ Res 84: 1007-1019, 1999.
    • (1999) Circ Res , vol.84 , pp. 1007-1019
    • Li, B.1    Setoguchi, M.2    Wang, X.3    Reoli, A.M.4    Leri, A.5    Malhotra, A.6    Kajstura, J.7    Anversa, P.8
  • 59
    • 84884675385 scopus 로고    scopus 로고
    • Swimming exercise traininginduced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway
    • Ma Z, Qi J, Meng S, Wen B, Zhang J. Swimming exercise traininginduced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway. Eur J Appl Physiol 113: 2473-2486, 2013.
    • (2013) Eur J Appl Physiol , vol.113 , pp. 2473-2486
    • Ma, Z.1    Qi, J.2    Meng, S.3    Wen, B.4    Zhang, J.5
  • 61
    • 84870200989 scopus 로고    scopus 로고
    • Can exercise teach us how to treat heart disease?
    • Mann N, Rosenzweig A. Can exercise teach us how to treat heart disease? Circulation 126: 2625-2635, 2012.
    • (2012) Circulation , vol.126 , pp. 2625-2635
    • Mann, N.1    Rosenzweig, A.2
  • 63
    • 0042750799 scopus 로고    scopus 로고
    • Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival
    • Matsui T, Nagoshi T, Rosenzweig A. Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival. Cell Cycle 2: 220-223, 2003.
    • (2003) Cell Cycle , vol.2 , pp. 220-223
    • Matsui, T.1    Nagoshi, T.2    Rosenzweig, A.3
  • 65
    • 0142027759 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase (P110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
    • McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Kang PM, Izumo S. Phosphoinositide 3-kinase (p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci USA 100: 12355-12360, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12355-12360
    • McMullen, J.R.1    Shioi, T.2    Zhang, L.3    Tarnavski, O.4    Sherwood, M.C.5    Kang, P.M.6    Izumo, S.7
  • 67
    • 0024264274 scopus 로고
    • Notes on the peroxidase activity of human basophil leukocytes
    • Mitsui T. Notes on the peroxidase activity of human basophil leukocytes. Tokai J Exp Clin Med 13: 1-8, 1988.
    • (1988) Tokai J Exp Clin Med , vol.13 , pp. 1-8
    • Mitsui, T.1
  • 68
    • 0034599128 scopus 로고    scopus 로고
    • Myosin heavy chain isoform expression in the failing and nonfailing human heart
    • Miyata S, Minobe W, Bristow MR, Leinwand LA. Myosin heavy chain isoform expression in the failing and nonfailing human heart. Circ Res 86: 386-390, 2000.
    • (2000) Circ Res , vol.86 , pp. 386-390
    • Miyata, S.1    Minobe, W.2    Bristow, M.R.3    Leinwand, L.A.4
  • 71
    • 84927175073 scopus 로고    scopus 로고
    • Myocardial remodeling in hypertension
    • Nadruz W. Myocardial remodeling in hypertension. J Hum Hypertens 29: 1-6, 2015.
    • (2015) J Hum Hypertens , vol.29 , pp. 1-6
    • Nadruz, W.1
  • 73
    • 25444503555 scopus 로고    scopus 로고
    • Chronic ß-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin
    • Oliveira EM, Krieger JE. Chronic ß-adrenoceptor stimulation and cardiac hypertrophy with no induction of circulating renin. Eur J Pharmacol 520: 135-141, 2005.
    • (2005) Eur J Pharmacol , vol.520 , pp. 135-141
    • Oliveira, E.M.1    Krieger, J.E.2
  • 74
    • 68149168072 scopus 로고    scopus 로고
    • Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice
    • Oliveira RS, Ferreira JC, Gomes ER, Paixão NA, Rolim NP, Medeiros A, Guatimosim S, Brum PC. Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice. J Physiol 587: 3899-3910, 2009.
    • (2009) J Physiol , vol.587 , pp. 3899-3910
    • Oliveira, R.S.1    Ferreira, J.C.2    Gomes, E.R.3    Paixão, N.A.4    Rolim, N.P.5    Medeiros, A.6    Guatimosim, S.7    Brum, P.C.8
  • 75
    • 84893197806 scopus 로고    scopus 로고
    • The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy
    • Ooi JY, Bernardo BC, McMullen JR. The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy. Future Med Chem 6: 205-222, 2014.
    • (2014) Future Med Chem , vol.6 , pp. 205-222
    • Ooi, J.Y.1    Bernardo, B.C.2    McMullen, J.R.3
  • 76
    • 84890441043 scopus 로고    scopus 로고
    • Potential benefits of exercise on blood pressure and vascular function
    • Pal S, Radavelli-Bagatini S, Ho S. Potential benefits of exercise on blood pressure and vascular function. J Am Soc Hypertens 7: 494-506, 2013.
    • (2013) J am Soc Hypertens , vol.7 , pp. 494-506
    • Pal, S.1    Radavelli-Bagatini, S.2    Ho, S.3
  • 79
    • 84890094732 scopus 로고    scopus 로고
    • Exercise-induced improvements in myocardial antioxidant capacity: The antioxidant players and cardioprotection
    • Powers SK, Sollanek KJ, Wiggs MP, Demirel HA, Smuder AJ. Exercise-induced improvements in myocardial antioxidant capacity: the antioxidant players and cardioprotection. Free Radic Res 48: 43-51, 2014.
    • (2014) Free Radic Res , vol.48 , pp. 43-51
    • Powers, S.K.1    Sollanek, K.J.2    Wiggs, M.P.3    Demirel, H.A.4    Smuder, A.J.5
  • 80
    • 4344583344 scopus 로고    scopus 로고
    • What makes vessels grow with exercise training
    • Prior BM, Yang HT, Terjung RL. What makes vessels grow with exercise training? J Appl Physiol 97: 1119-1128, 2004.
    • (2004) J Appl Physiol , vol.97 , pp. 1119-1128
    • Prior, B.M.1    Yang, H.T.2    Terjung, R.L.3
  • 81
    • 84925869307 scopus 로고    scopus 로고
    • MiRNAs with apoptosis regulating potential are differentially expressed in chronic exercise-induced physiologically hypertrophied hearts
    • Ramasamy S, Velmurugan G, Shanmugha Rajan K, Ramprasath T, Kalpana K. MiRNAs with apoptosis regulating potential are differentially expressed in chronic exercise-induced physiologically hypertrophied hearts. PLoS One 10: e0121401, 2015.
    • (2015) Plos One , vol.10
    • Ramasamy, S.1    Velmurugan, G.2    Shanmugha Rajan, K.3    Ramprasath, T.4    Kalpana, K.5
  • 82
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNAs play an essential role in the development of cardiac hypertrophy
    • Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res 100: 416-424, 2007.
    • (2007) Circ Res , vol.100 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.Y.3    Lypowy, J.4    Abdellatif, M.5
  • 83
    • 0033596643 scopus 로고    scopus 로고
    • Exercise as cardiovascular therapy
    • Shephard RJ, Balady GJ. Exercise as cardiovascular therapy. Circulation 99: 963-972, 1999.
    • (1999) Circulation , vol.99 , pp. 963-972
    • Shephard, R.J.1    Balady, G.J.2
  • 84
    • 79955800181 scopus 로고    scopus 로고
    • Elevated miR-499 levels blunt the cardiac stress response
    • Shieh JT, Huang Y, Gilmore J, Srivastava D. Elevated miR-499 levels blunt the cardiac stress response. PLoS One 6: e19481, 2011.
    • (2011) Plos One , vol.6
    • Shieh, J.T.1    Huang, Y.2    Gilmore, J.3    Srivastava, D.4
  • 85
    • 23644439061 scopus 로고    scopus 로고
    • Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
    • Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. J Clin Invest 115: 2108-2118, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 2108-2118
    • Shiojima, I.1    Sato, K.2    Izumiya, Y.3    Schiekofer, S.4    Ito, M.5    Liao, R.6    Colucci, W.S.7    Walsh, K.8
  • 86
    • 78751660177 scopus 로고    scopus 로고
    • Pervasive roles of microRNAs in cardiovascular biology
    • Small EM, Olson EN. Pervasive roles of microRNAs in cardiovascular biology. Nature 469: 336-342, 2011.
    • (2011) Nature , vol.469 , pp. 336-342
    • Small, E.M.1    Olson, E.N.2
  • 89
    • 77951251172 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase
    • Stahmann N, Woods A, Spengler K, Heslegrave A, Bauer R, Krause S, Viollet B, Carling D, Heller R. Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase. J Biol Chem 285: 10638-10652, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 10638-10652
    • Stahmann, N.1    Woods, A.2    Spengler, K.3    Heslegrave, A.4    Bauer, R.5    Krause, S.6    Viollet, B.7    Carling, D.8    Heller, R.9
  • 90
    • 34548402049 scopus 로고    scopus 로고
    • Exercise-induced cardioprotection: Endogenous mechanisms
    • Starnes JW, Taylor RP. Exercise-induced cardioprotection: endogenous mechanisms. Med Sci Sports Exerc 39: 1537-1543, 2007.
    • (2007) Med Sci Sports Exerc , vol.39 , pp. 1537-1543
    • Starnes, J.W.1    Taylor, R.P.2
  • 96
    • 84908156168 scopus 로고    scopus 로고
    • Natriuretic peptides and cardio-renal disease
    • Volpe M. Natriuretic peptides and cardio-renal disease. Int J Cardiol 176: 630-639, 2014.
    • (2014) Int J Cardiol , vol.176 , pp. 630-639
    • Volpe, M.1
  • 98
    • 79955161098 scopus 로고    scopus 로고
    • The athlete’s heart vs. The failing heart: Can signaling explain the two distinct outcomes?
    • Bethesda
    • Weeks KL, McMullen JR. The athlete’s heart vs. the failing heart: can signaling explain the two distinct outcomes? Physiology (Bethesda) 26: 97-105, 2011.
    • (2011) Physiology , vol.26 , pp. 97-105
    • Weeks, K.L.1    McMullen, J.R.2
  • 99
    • 84925861773 scopus 로고    scopus 로고
    • Long noncoding RNA-MicroRNA-mRNA: A novel tripartite axis in the regulation of cardiac hypertrophy
    • Wu C, Arora P. Long noncoding RNA-MicroRNA-mRNA: a novel tripartite axis in the regulation of cardiac hypertrophy. Circ Cardiovasc Genet 7: 729-731, 2014.
    • (2014) Circ Cardiovasc Genet , vol.7 , pp. 729-731
    • Wu, C.1    Arora, P.2
  • 100
    • 15744391012 scopus 로고    scopus 로고
    • Dicer is required for embryonic angiogenesis during mouse development
    • Yang WJ, Yang DD, Na S, Sandusky GE, Zhang Q, Zhao G. Dicer is required for embryonic angiogenesis during mouse development. J Biol Chem 280: 9330-9335, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 9330-9335
    • Yang, W.J.1    Yang, D.D.2    Na, S.3    Sandusky, G.E.4    Zhang, Q.5    Zhao, G.6
  • 101
    • 6344250896 scopus 로고    scopus 로고
    • Natriuretic peptides, respiratory disease, and the right heart
    • Yap Bin L, Mukerjee D, Timms PM, Ashrafian H, Coghlan JG. Natriuretic peptides, respiratory disease, and the right heart. Chest 126: 1330-1336, 2004.
    • (2004) Chest , vol.126 , pp. 1330-1336
    • Yap Bin, L.1    Mukerjee, D.2    Timms, P.M.3    Ashrafian, H.4    Coghlan, J.G.5
  • 102
    • 84908075392 scopus 로고    scopus 로고
    • Adverse left ventricular remodeling in community-dwelling older adults predicts incident heart failure and mortality
    • Zile MR, Gaasch WH, Patel K, Aban IB Ahmed A. Adverse left ventricular remodeling in community-dwelling older adults predicts incident heart failure and mortality. JACC Heart Fail 2: 512-522, 2014.
    • (2014) JACC Heart Fail , vol.2 , pp. 512-522
    • Zile, M.R.1    Gaasch, W.H.2    Patel, K.3    Aban Ib Ahmed, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.