메뉴 건너뛰기




Volumn 41, Issue 3, 2012, Pages 1110-1118

Periostin activates integrin α5β1 through a PI3K/AKT-dependent, pathway in invasion of cholangiocarcinoma

Author keywords

Cholangiocarcinoma; Fibroblast; Integrin; Invasion; Periostin; PI3K AKT

Indexed keywords

ALPHA6BETA4 INTEGRIN; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR RUNX2; VERY LATE ACTIVATION ANTIGEN 5;

EID: 84864981474     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1530     Document Type: Article
Times cited : (93)

References (50)
  • 1
    • 11244335567 scopus 로고    scopus 로고
    • Cholangiocarcinoma: Molecular targeting strategies for chemoprevention and therapy
    • Sirica AE: Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. Hepatology 41: 5-15, 2005.
    • (2005) Hepatology , vol.41 , pp. 5-15
    • Sirica, A.E.1
  • 5
    • 67449098972 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma
    • Chuaysri C, Thuwajit P, Paupairoj A, Chau-In S, Suthiphongchai T and Thuwajit C: Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma. Oncol Rep 21: 957-969, 2009.
    • (2009) Oncol Rep , vol.21 , pp. 957-969
    • Chuaysri, C.1    Thuwajit, P.2    Paupairoj, A.3    Chau-In, S.4    Suthiphongchai, T.5    Thuwajit, C.6
  • 6
    • 77649298501 scopus 로고    scopus 로고
    • Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker
    • Utispan K, Thuwajit P, Abiko Y, et al: Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker. Mol Cancer 9: 13, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 13
    • Utispan, K.1    Thuwajit, P.2    Abiko, Y.3
  • 7
    • 79955060818 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma
    • Sirica AE, Campbell DJ and Dumur CI: Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma. Curr Opin Gastroenterol 27: 276-284, 2011.
    • (2011) Curr Opin Gastroenterol , vol.27 , pp. 276-284
    • Sirica, A.E.1    Campbell, D.J.2    Dumur, C.I.3
  • 8
    • 0030175364 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin-positive stromal cells in cholangiocarcinomas, hepatocellular carcinomas and metastatic liver carcinomas
    • Terada T, Makimoto K, Terayama N, Suzuki Y and Nakanuma Y: Alpha-smooth muscle actin-positive stromal cells in cholangiocarcinomas, hepatocellular carcinomas and metastatic liver carcinomas. J Hepatol 24: 706-712, 1996.
    • (1996) J Hepatol , vol.24 , pp. 706-712
    • Terada, T.1    Makimoto, K.2    Terayama, N.3    Suzuki, Y.4    Nakanuma, Y.5
  • 9
    • 79952536603 scopus 로고    scopus 로고
    • Proteomic analysis of differentially expressed proteins in peripheral cholangiocarcinoma
    • Darby IA, Vuillier-Devillers K, Pinault E, et al: Proteomic analysis of differentially expressed proteins in peripheral cholangiocarcinoma. Cancer Microenviron 4: 73-91, 2010.
    • (2010) Cancer Microenviron , vol.4 , pp. 73-91
    • Darby, I.A.1    Vuillier-Devillers, K.2    Pinault, E.3
  • 10
    • 78249270441 scopus 로고    scopus 로고
    • Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas
    • Dumur CI, Campbell DJ, DeWitt JL, Oyesanya RA and Sirica AE: Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas. Exp Mol Pathol 89: 227-235, 2010.
    • (2010) Exp Mol Pathol , vol.89 , pp. 227-235
    • Dumur, C.I.1    Campbell, D.J.2    DeWitt, J.L.3    Oyesanya, R.A.4    Sirica, A.E.5
  • 11
    • 67650451085 scopus 로고    scopus 로고
    • The multifaceted role of periostin in tumorigenesis
    • Ruan K, Bao S and Ouyang G: The multifaceted role of periostin in tumorigenesis. Cell Mol Life Sci 66: 2219-2230, 2009.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 2219-2230
    • Ruan, K.1    Bao, S.2    Ouyang, G.3
  • 12
    • 34247236139 scopus 로고    scopus 로고
    • Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
    • Erkan M, Kleeff J, Gorbachevski A, et al: Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 132: 1447-1464, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 1447-1464
    • Erkan, M.1    Kleeff, J.2    Gorbachevski, A.3
  • 13
    • 48749102426 scopus 로고    scopus 로고
    • Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas
    • Fukushima N, Kikuchi Y, Nishiyama T, Kudo A and Fukayama M: Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas. Mod Pathol 21: 1044-1053, 2008.
    • (2008) Mod Pathol , vol.21 , pp. 1044-1053
    • Fukushima, N.1    Kikuchi, Y.2    Nishiyama, T.3    Kudo, A.4    Fukayama, M.5
  • 14
    • 34948858033 scopus 로고    scopus 로고
    • Expression of periostin and its clinicopathological relevance in gastric cancer
    • Li JS, Sun GW, Wei XY and Tang WH: Expression of periostin and its clinicopathological relevance in gastric cancer. World J Gastroenterol 13: 5261-5266, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 5261-5266
    • Li, J.S.1    Sun, G.W.2    Wei, X.Y.3    Tang, W.H.4
  • 15
    • 42049120469 scopus 로고    scopus 로고
    • Expression of periostin in human breast cancer
    • Puglisi F, Puppin C, Pegolo E, et al: Expression of periostin in human breast cancer. J Clin Pathol 61: 494-498, 2008.
    • (2008) J Clin Pathol , vol.61 , pp. 494-498
    • Puglisi, F.1    Puppin, C.2    Pegolo, E.3
  • 16
    • 43849089837 scopus 로고    scopus 로고
    • High periostin expression correlates with aggressiveness in papillary thyroid carcinomas
    • Puppin C, Fabbro D, Dima M, et al: High periostin expression correlates with aggressiveness in papillary thyroid carcinomas. J Endocrinol 197: 401-408, 2008.
    • (2008) J Endocrinol , vol.197 , pp. 401-408
    • Puppin, C.1    Fabbro, D.2    Dima, M.3
  • 17
    • 58149385884 scopus 로고    scopus 로고
    • Expression of periostin in patients with non-small cell lung cancer: Correlation with angiogenesis and lymphangiogenesis
    • Takanami I, Abiko T and Koizumi S: Expression of periostin in patients with non-small cell lung cancer: correlation with angiogenesis and lymphangiogenesis. Int J Biol Markers 23: 182-186, 2008.
    • (2008) Int J Biol Markers , vol.23 , pp. 182-186
    • Takanami, I.1    Abiko, T.2    Koizumi, S.3
  • 18
    • 0037105657 scopus 로고    scopus 로고
    • Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility
    • Gillan L, Matei D, Fishman DA, Gerbin CS, Karlan BY and Chang DD: Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility. Cancer Res 62: 5358-5364, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5358-5364
    • Gillan, L.1    Matei, D.2    Fishman, D.A.3    Gerbin, C.S.4    Karlan, B.Y.5    Chang, D.D.6
  • 19
    • 33746895756 scopus 로고    scopus 로고
    • Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer
    • Kudo Y, Ogawa I, Kitajima S, et al: Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res 66: 6928-6935, 2006.
    • (2006) Cancer Res , vol.66 , pp. 6928-6935
    • Kudo, Y.1    Ogawa, I.2    Kitajima, S.3
  • 20
    • 11144357346 scopus 로고    scopus 로고
    • Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway
    • Bao S, Ouyang G, Bai X, et al: Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell 5: 329-339, 2004.
    • (2004) Cancer Cell , vol.5 , pp. 329-339
    • Bao, S.1    Ouyang, G.2    Bai, X.3
  • 21
    • 34047093817 scopus 로고    scopus 로고
    • Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: Role of the beta4 integrin and the PI3k pathway
    • Baril P, Gangeswaran R, Mahon PC, et al: Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene 26: 2082-2094, 2007.
    • (2007) Oncogene , vol.26 , pp. 2082-2094
    • Baril, P.1    Gangeswaran, R.2    Mahon, P.C.3
  • 22
    • 74749093368 scopus 로고    scopus 로고
    • Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway
    • Li G, Jin R, Norris RA, et al: Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway. Atherosclerosis 208: 358-365, 2010.
    • (2010) Atherosclerosis , vol.208 , pp. 358-365
    • Li, G.1    Jin, R.2    Norris, R.A.3
  • 23
    • 1942422179 scopus 로고    scopus 로고
    • Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression
    • Shao R, Bao S, Bai X, et al: Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression. Mol Cell Biol 24: 3992-4003, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 3992-4003
    • Shao, R.1    Bao, S.2    Bai, X.3
  • 24
    • 33745835073 scopus 로고    scopus 로고
    • Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation
    • Yan W and Shao R: Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation. J Biol Chem 281: 19700-19708, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 19700-19708
    • Yan, W.1    Shao, R.2
  • 25
    • 21044433748 scopus 로고    scopus 로고
    • Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100)
    • Sripa B, Leungwattanawanit S, Nitta T, et al: Establishment and characterization of an opisthorchiasis-associated cholangiocarcinoma cell line (KKU-100). World J Gastroenterol 11: 3392-3397, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 3392-3397
    • Sripa, B.1    Leungwattanawanit, S.2    Nitta, T.3
  • 26
    • 10744221503 scopus 로고    scopus 로고
    • Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT
    • Maruyama M, Kobayashi N, Westerman KA, et al: Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT. Transplantation 77: 446-451, 2004.
    • (2004) Transplantation , vol.77 , pp. 446-451
    • Maruyama, M.1    Kobayashi, N.2    Westerman, K.A.3
  • 29
    • 42549152045 scopus 로고    scopus 로고
    • No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
    • Qiu W, Hu M, Sridhar A, et al: No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet 40: 650-655, 2008.
    • (2008) Nat Genet , vol.40 , pp. 650-655
    • Qiu, W.1    Hu, M.2    Sridhar, A.3
  • 30
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: Interactions with the tumor stroma
    • Pietras K and Ostman A: Hallmarks of cancer: interactions with the tumor stroma. Exp Cell Res 316: 1324-1331, 2010.
    • (2010) Exp Cell Res , vol.316 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 31
    • 75849116069 scopus 로고    scopus 로고
    • Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?
    • Gonda TA, Varro A, Wang TC and Tycko B: Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin Cell Dev Biol 21: 2-10, 2010.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 2-10
    • Gonda, T.A.1    Varro, A.2    Wang, T.C.3    Tycko, B.4
  • 32
    • 77956883321 scopus 로고    scopus 로고
    • Activation of fibroblasts in cancer stroma
    • Rasanen K and Vaheri A: Activation of fibroblasts in cancer stroma. Exp Cell Res 316: 2713-2722, 2010.
    • (2010) Exp Cell Res , vol.316 , pp. 2713-2722
    • Rasanen, K.1    Vaheri, A.2
  • 34
    • 69449095344 scopus 로고    scopus 로고
    • Differential influence of normal and cancer-associated fibroblasts on the growth of human epithelial cells in an in vitro cocultivation model of prostate cancer
    • Paland N, Kamer I, Kogan-Sakin I, Madar S, Goldfinger N and Rotter V: Differential influence of normal and cancer-associated fibroblasts on the growth of human epithelial cells in an in vitro cocultivation model of prostate cancer. Mol Cancer Res 7: 1212-1223, 2009.
    • (2009) Mol Cancer Res , vol.7 , pp. 1212-1223
    • Paland, N.1    Kamer, I.2    Kogan-Sakin, I.3    Madar, S.4    Goldfinger, N.5    Rotter, V.6
  • 35
    • 0027773003 scopus 로고
    • Integrins as differential cell lineage markers of primary liver tumors
    • Volpes R, van den Oord JJ and Desmet VJ: Integrins as differential cell lineage markers of primary liver tumors. Am J Pathol 142: 1483-1492, 1993.
    • (1993) Am J Pathol , vol.142 , pp. 1483-1492
    • Volpes, R.1    Van Den Oord, J.J.2    Desmet, V.J.3
  • 36
    • 0032437831 scopus 로고    scopus 로고
    • Integrins: Utility as cell type- and stage-specific markers for hepatocellular carcinoma and cholangiocarcinoma
    • Enjoji M, Sakai H, Nakashima M and Nawata H: Integrins: utility as cell type- and stage-specific markers for hepatocellular carcinoma and cholangiocarcinoma. In Vitro Cell Dev Biol Anim 34: 25-27, 1998.
    • (1998) In Vitro Cell Dev Biol Anim , vol.34 , pp. 25-27
    • Enjoji, M.1    Sakai, H.2    Nakashima, M.3    Nawata, H.4
  • 37
    • 77249113715 scopus 로고    scopus 로고
    • The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma
    • Patsenker E, Wilkens L, Banz V, et al: The alphavbeta6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma. J Hepatol 52: 362-369, 2010.
    • (2010) J Hepatol , vol.52 , pp. 362-369
    • Patsenker, E.1    Wilkens, L.2    Banz, V.3
  • 38
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO: Integrins: bidirectional, allosteric signaling machines. Cell 110: 673-687, 2002.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 39
    • 67349256386 scopus 로고    scopus 로고
    • Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway
    • Ouyang G, Liu M, Ruan K, Song G, Mao Y and Bao S: Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway. Cancer Lett 281: 213-219, 2009.
    • (2009) Cancer Lett , vol.281 , pp. 213-219
    • Ouyang, G.1    Liu, M.2    Ruan, K.3    Song, G.4    Mao, Y.5    Bao, S.6
  • 41
    • 68049137909 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT pathway for the treatment of prostate cancer
    • Sarker D, Reid AH, Yap TA and de Bono JS: Targeting the PI3K/AKT pathway for the treatment of prostate cancer. Clin Cancer Res 15: 4799-4805, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 4799-4805
    • Sarker, D.1    Reid, A.H.2    Yap, T.A.3    De Bono, J.S.4
  • 42
    • 79953792348 scopus 로고    scopus 로고
    • Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration
    • Yadav V and Denning MF: Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration. Mol Carcinog 50: 346-352, 2011.
    • (2011) Mol Carcinog , vol.50 , pp. 346-352
    • Yadav, V.1    Denning, M.F.2
  • 43
    • 78649720692 scopus 로고    scopus 로고
    • Alpha5beta1-integrin expression is essential for tumor progression in experimental lung cancer
    • Roman J, Ritzenthaler JD, Roser-Page S, Sun X and Han S: alpha5beta1-integrin expression is essential for tumor progression in experimental lung cancer. Am J Respir Cell Mol Biol 43: 684-691, 2010.
    • (2010) Am J Respir Cell Mol Biol , vol.43 , pp. 684-691
    • Roman, J.1    Ritzenthaler, J.D.2    Roser-Page, S.3    Sun, X.4    Han, S.5
  • 44
    • 79551530752 scopus 로고    scopus 로고
    • Integrin alpha5beta1 facilitates cancer cell invasion through enhanced contractile forces
    • Mierke CT, Frey B, Fellner M, Herrmann M and Fabry B: Integrin alpha5beta1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci 124: 369-383, 2011.
    • (2011) J Cell Sci , vol.124 , pp. 369-383
    • Mierke, C.T.1    Frey, B.2    Fellner, M.3    Herrmann, M.4    Fabry, B.5
  • 45
    • 68049114597 scopus 로고    scopus 로고
    • Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity
    • Morozevich G, Kozlova N, Cheglakov I, Ushakova N and Berman A: Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity. Cell Cycle 8: 2219-2225, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 2219-2225
    • Morozevich, G.1    Kozlova, N.2    Cheglakov, I.3    Ushakova, N.4    Berman, A.5
  • 46
    • 3543052060 scopus 로고    scopus 로고
    • Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues
    • Castillo SS, Brognard J, Petukhov PA, et al: Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues. Cancer Res 64: 2782-2792, 2004.
    • (2004) Cancer Res , vol.64 , pp. 2782-2792
    • Castillo, S.S.1    Brognard, J.2    Petukhov, P.A.3
  • 47
    • 79958099193 scopus 로고    scopus 로고
    • Role of periostin in cancer progression and metastasis: Inhibition of breast cancer progression and metastasis by anti-periostin antibody in a murine model
    • Kyutoku M, Taniyama Y, Katsuragi N, et al: Role of periostin in cancer progression and metastasis: inhibition of breast cancer progression and metastasis by anti-periostin antibody in a murine model. Int J Mol Med 28: 181-186, 2011.
    • (2011) Int J Mol Med , vol.28 , pp. 181-186
    • Kyutoku, M.1    Taniyama, Y.2    Katsuragi, N.3
  • 49
    • 77953215965 scopus 로고    scopus 로고
    • In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine
    • Li Z, Tan F, Liewehr DJ, Steinberg SM and Thiele CJ: In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine. J Natl Cancer Inst 102: 758-770, 2010.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 758-770
    • Li, Z.1    Tan, F.2    Liewehr, D.J.3    Steinberg, S.M.4    Thiele, C.J.5
  • 50
    • 77958509195 scopus 로고    scopus 로고
    • Akt inhibitors in clinical development for the treatment of cancer
    • Pal SK, Reckamp K, Yu H and Figlin RA: Akt inhibitors in clinical development for the treatment of cancer. Expert Opin Investig Drugs 19: 1355-1366, 2010.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 1355-1366
    • Pal, S.K.1    Reckamp, K.2    Yu, H.3    Figlin, R.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.