System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice

Brain : a journal of neurology

Volumn 138, Issue , 2015, Pages 53-68

  Mesci, Pinar ^a   Zaïdi, Sakina ^a   Lobsiger, Christian S ^a   Millecamps, Stéphanie ^a   Escartin, Carole ^a   Seilhean, Danielle ^a   Sato, Hideyo ^a   Mallat, Michel ^a   Boillée, Séverine ^a  

^a SORBONNE UNIVERSITÉ   (France)

Author keywords

ALS; excitotoxicity; motoneuron; neuroinflammation; xCT

Indexed keywords

AMINO ACID TRANSPORTER; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOKINE; GLUTATHIONE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SOD1 G37R PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MICROGLIA; MORTALITY; MOTONEURON; MOUSE; MUTATION; NEWBORN; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

AMINO ACID TRANSPORT SYSTEM ASC; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, NEWBORN; CEREBRAL CORTEX; CYTOKINES; DISEASE MODELS, ANIMAL; GLUTATHIONE; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MOTOR NEURONS; MUTATION; NITRIC OXIDE; SUPEROXIDE DISMUTASE;

EID: 84925231252     PISSN: None     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu312     Document Type: Article

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