Human chorionic gonadotropin has anti-inflammatory effects at the maternal-fetal interface and prevents endotoxin-induced preterm birth, but causes dystocia and fetal compromise in mice

Biology of Reproduction

Volumn 94, Issue 6, 2016, Pages

  Furcron, Amy Eunice ^a,b   Romero, Roberto ^a,c,d,e   Mial, Tara N ^a,b   Balancio, Amapola ^a   Panaitescu, Bogdan ^a   Hassan, Sonia S ^a,b   Sahi, Aashna ^b   Nord, Claire ^a   Gomez Lopez, Nardhy ^a,b,f  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

^e WAYNE STATE UNIVERSITY   (United States)

^f WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Decidua; Estradiol; hCG; Interleukin 1 ; M1 macrophages; M2 macrophages; Mouse; Neutrophils; Parturition; Pregnancy; Preterm labor; Progesterone; Regulatory T cells; Th17 cells

Indexed keywords

CHORIONIC GONADOTROPIN; ENDOTOXIN; ESTRADIOL; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; PROGESTERONE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL POLARITY; CONTROLLED STUDY; DECIDUA; DOPPLER ULTRASONOGRAPHY; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DYSTOCIA; ENZYME LINKED IMMUNOSORBENT ASSAY; ESTRADIOL BLOOD LEVEL; FEMALE; FETAL COMPROMISE; FETOPLACENTAL UNIT; FETOTOXICITY; FETUS; IMMUNOPHENOTYPING; MACROPHAGE; MICROENVIRONMENT; MOUSE; NEUTROPHIL; NONHUMAN; PREMATURE LABOR; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; REGULATORY T LYMPHOCYTE; TH17 CELL; ANIMAL; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; FETUS ECHOGRAPHY; IMMUNOLOGY; LEUKOCYTE; MALE; PREGNANCY; PREMATURE BIRTH;

ANIMALS; CHORIONIC GONADOTROPIN; DECIDUA; DYSTOCIA; ENDOTOXINS; ESTRADIOL; FEMALE; FETUS; INTERLEUKIN-1BETA; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; PREGNANCY; PREMATURE BIRTH; PROGESTERONE; ULTRASONOGRAPHY, PRENATAL;

EID: 84978859411     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.116.139345     Document Type: Article

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