Geniposide Prevents Hypoxia/Reoxygenation-Induced Apoptosis in H9c2 Cells: Improvement of Mitochondrial Dysfunction and Activation of GLP-1R and the PI3K/AKT Signaling Pathway

Cellular Physiology and Biochemistry

Volumn 39, Issue 1, 2016, Pages 407-421

  Jiang, You Qin ^a   Chang, Guang Lei ^a   Wang, Ying ^a   Zhang, Dong Ying ^a   Cao, Li ^a   Liu, Jian ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Cardiomyocyte apoptosis; Geniposide; GLP 1R; Hypoxia reoxygenation; Mitochondria

Indexed keywords

CALCIUM; CASPASE 3; CYTOCHROME C; GENIPOSIDE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; LACTATE DEHYDROGENASE; LIPOCORTIN 5; MALONALDEHYDE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; GLP1R PROTEIN, RAT; HERBACEOUS AGENT; IRIDOID; OXYGEN;

APOPTOSIS; ARTICLE; ASSAY; CARDIAC MUSCLE CELL; CELL COUNTING; CELL HYPOXIA; CELL STRUCTURE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DEPOLARIZATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; GENE EXPRESSION; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAINING; SUPERNATANT; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG EFFECT; GENETICS; HEART MITOCHONDRION; METABOLISM; PHYSIOLOGY; RAT; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; DRUGS, CHINESE HERBAL; GENE EXPRESSION; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; IRIDOIDS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OXYGEN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84978151502     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000445634     Document Type: Article

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