메뉴 건너뛰기




Volumn 34, Issue 1, 2014, Pages 119-129

PE-induced apoptosis in SMMC-7721 cells: Involvement of Erk and Stat signalling pathways

Author keywords

Apoptosis; Erk; Phosphatidylethanolamine; SMMC 7721 cells; Stat

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE 6; PHOSPHATIDYLETHANOLAMINE; PROTEIN BAX; PROTEIN BCL 2; STAT PROTEIN; STAT1 PROTEIN; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE; STAT1 PROTEIN, HUMAN; STAT2 PROTEIN; STAT2 PROTEIN, HUMAN;

EID: 84902688399     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1777     Document Type: Article
Times cited : (16)

References (54)
  • 1
    • 84855230886 scopus 로고    scopus 로고
    • Lantibiotics as probes for phosphatidylethanolamine
    • Zhao M: Lantibiotics as probes for phosphatidylethanolamine. Amino Acids 41: 1071-1079, 2011.
    • (2011) Amino Acids , vol.41 , pp. 1071-1079
    • Zhao, M.1
  • 2
    • 0028927397 scopus 로고
    • Phosphatidylethanolamine and sarcolemmal damage during ischemia or metabolic inhibition of heart myocytes
    • Post JA, Bijvelt JJ and Verkleij AJ: Phosphatidylethanolamine and sarcolemmal damage during ischemia or metabolic inhibition of heart myocytes. Am J Physiol 268: H773-H780, 1995.
    • (1995) Am J Physiol , vol.268
    • Post, J.A.1    Bijvelt, J.J.2    Verkleij, A.J.3
  • 3
    • 48749103305 scopus 로고    scopus 로고
    • 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe
    • Zhao M, Li Z and Bugenhagen S: 99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe. J Nucl Med 49: 1345-1352, 2008.
    • (2008) J Nucl Med , vol.49 , pp. 1345-1352
    • Zhao, M.1    Li, Z.2    Bugenhagen, S.3
  • 4
    • 65649126424 scopus 로고    scopus 로고
    • Exogenous phosphatidylethanolamine induces apoptosis of human hepatoma HepG2 cells via the bcl-2/Bax pathway
    • Yao Y, Huang C, Li ZF, et al: Exogenous phosphatidylethanolamine induces apoptosis of human hepatoma HepG2 cells via the bcl-2/Bax pathway. World J Gastroenterol 15: 1751-1758, 2009.
    • (2009) World J Gastroenterol , vol.15 , pp. 1751-1758
    • Yao, Y.1    Huang, C.2    Li, Z.F.3
  • 5
    • 37149039846 scopus 로고    scopus 로고
    • Apoptosis commitment - Translating survival signals into decisions on mitochondria
    • DOI 10.1038/cr.2007.101, PII CR2007101
    • Keeble JA and Gilmore AP: Apoptosis commitment-translating survival signals into decisions on mitochondria. Cell Res 17: 976-984, 2007. (Pubitemid 350261795)
    • (2007) Cell Research , vol.17 , Issue.12 , pp. 976-984
    • Keeble, J.A.1    Gilmore, A.P.2
  • 6
    • 1542359516 scopus 로고    scopus 로고
    • Central role of mitochondria and p53 in Fas-mediated apoptosis of rheumatoid synovial fibroblasts
    • DOI 10.1093/rheumatology/keh039
    • Itoh K, Hase H, Kojima H, Saotome K, Nishioka K and Kobata T: Central role of mitochondria and p53 in Fas-mediated apoptosis of rheumatoid synovial fibroblasts. Rheumatology (Oxford) 43: 277-285, 2004. (Pubitemid 38313174)
    • (2004) Rheumatology , vol.43 , Issue.3 , pp. 277-285
    • Itoh, K.1    Hase, H.2    Kojima, H.3    Saotome, K.4    Nishioka, K.5    Kobata, T.6
  • 7
    • 45349094984 scopus 로고    scopus 로고
    • Mitochondrial dynamics and apoptosis
    • DOI 10.1101/gad.1658508
    • Suen DF, Norris KL and Youle RJ: Mitochondrial dynamics and apoptosis. Genes Dev 22: 1577-1590, 2008. (Pubitemid 351846838)
    • (2008) Genes and Development , vol.22 , Issue.12 , pp. 1577-1590
    • Suen, D.-F.1    Norris, K.L.2    Youle, R.J.3
  • 8
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • DOI 10.1038/sj.onc.1210220, PII 1210220
    • Adams JM and Cory S: The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337, 2007. (Pubitemid 46328466)
    • (2007) Oncogene , vol.26 , Issue.9 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 9
    • 41149152733 scopus 로고    scopus 로고
    • How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
    • Chipuk JE and Green DR: How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 18: 157-164, 2008.
    • (2008) Trends Cell Biol , vol.18 , pp. 157-164
    • Chipuk, J.E.1    Green, D.R.2
  • 10
    • 84876017276 scopus 로고    scopus 로고
    • Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells
    • Jiang L, Liu Y, Ma MM, Tang YB, Zhou JG and Guan YY: Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells. Apoptosis 18: 556-565, 2013.
    • (2013) Apoptosis , vol.18 , pp. 556-565
    • Jiang, L.1    Liu, Y.2    Ma, M.M.3    Tang, Y.B.4    Zhou, J.G.5    Guan, Y.Y.6
  • 11
    • 64849113485 scopus 로고    scopus 로고
    • Control of mitochondrial apoptosis by the Bcl-2 family
    • Brunelle JK and Letai A: Control of mitochondrial apoptosis by the Bcl-2 family. J Cell Sci 122: 437-441, 2009.
    • (2009) J Cell Sci , vol.122 , pp. 437-441
    • Brunelle, J.K.1    Letai, A.2
  • 13
    • 0033529638 scopus 로고    scopus 로고
    • Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
    • Hetman M, Kanning K, Cavanaugh JE and Xia Z: Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J Biol Chem 274: 22569-22580, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 22569-22580
    • Hetman, M.1    Kanning, K.2    Cavanaugh, J.E.3    Xia, Z.4
  • 14
    • 0035844129 scopus 로고    scopus 로고
    • MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
    • Tran SE, Holmstrom TH, Ahonen M, Kahari VM and Eriksson JE: MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J Biol Chem 276: 16484-16490, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 16484-16490
    • Tran, S.E.1    Holmstrom, T.H.2    Ahonen, M.3    Kahari, V.M.4    Eriksson, J.E.5
  • 15
    • 0034618369 scopus 로고    scopus 로고
    • MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
    • Boucher MJ, Morisset J, Vachon PH, Reed JC, Lainé J and Rivard N: MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem 79: 355-369, 2000.
    • (2000) J Cell Biochem , vol.79 , pp. 355-369
    • Boucher, M.J.1    Morisset, J.2    Vachon, P.H.3    Reed, J.C.4    Lainé, J.5    Rivard, N.6
  • 16
    • 0035862950 scopus 로고    scopus 로고
    • Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
    • DOI 10.1093/emboj/20.1.91
    • Kovarik P, Mangold M, Ramsauer K, et al: Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. EMBO J 20: 91-100, 2001. (Pubitemid 32099105)
    • (2001) EMBO Journal , vol.20 , Issue.1-2 , pp. 91-100
    • Kovarik, P.1    Mangold, M.2    Ramsauer, K.3    Heidari, H.4    Steinborn, R.5    Zotter, A.6    Levy, D.E.7    Muller, M.8    Decker, T.9
  • 17
    • 0036625960 scopus 로고    scopus 로고
    • The role of STATs in apoptosis
    • DOI 10.2174/1566524023362456
    • Battle TE and Frank DA: The role of STATs in apoptosis. Curr Mol Med 2: 381-392, 2002. (Pubitemid 35452886)
    • (2002) Current Molecular Medicine , vol.2 , Issue.4 , pp. 381-392
    • Battle, T.E.1    Frank, D.A.2
  • 18
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong Z and Darnell JE Jr: Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241-250, 1995.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 19
    • 0036731485 scopus 로고    scopus 로고
    • STATs: Transcriptional control and biological impact
    • DOI 10.1038/nrm909
    • Levy DE and Darnell JE Jr: Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3: 651-662, 2002. (Pubitemid 34987786)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.9 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 20
    • 0026770248 scopus 로고
    • Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler C, Shuai K, Prezioso VR and Darnell JE Jr: Pillars article: interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257: 809-813, 1992.
    • (1992) Science , vol.257 , pp. 809-813
    • Schindler, C.1    Shuai, K.2    Prezioso, V.R.3    Darnell Jr., J.E.4
  • 24
    • 0036628735 scopus 로고    scopus 로고
    • Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
    • DOI 10.1016/S0891-5849(02)00865-1, PII S0891584902008651
    • Pérez MJ and Cederbaum AI: Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. Free Radic Biol Med 33: 111-127, 2002. (Pubitemid 34681013)
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.1 , pp. 111-127
    • Perez, M.J.1    Cederbaum, A.I.2
  • 25
  • 26
    • 0034286928 scopus 로고    scopus 로고
    • Phosphatidylserine expression on apoptotic lymphocytes of Xenopus laevis, the South African clawed toad, as a signal for macrophage recognition
    • DOI 10.1016/S0145-305X(00)00020-3, PII S0145305X00000203
    • Nera MS, Vanderbeek G, Johnson RO, Ruben LN and Clothier RH: Phosphatidylserine expression on apoptotic lymphocytes of Xenopus laevis, the South African clawed toad, as a signal for macrophage recognition. Dev Comp Immunol 24: 641-652, 2000. (Pubitemid 30261488)
    • (2000) Developmental and Comparative Immunology , vol.24 , Issue.6-7 , pp. 641-652
    • Nera, M.S.1    Vanderbeek, G.2    Johnson, R.O.3    Ruben, L.N.4    Clothier, R.H.5
  • 27
    • 0034059440 scopus 로고    scopus 로고
    • Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
    • Murphy KM, Ranganathan V, Farnsworth ML, Kavallaris M and Lock RB: Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ 7: 102-111, 2000. (Pubitemid 30153768)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.1 , pp. 102-111
    • Murphy, K.M.1    Ranganathan, V.2    Farnsworth, M.L.3    Kavallaris, M.4    Lock, R.B.5
  • 28
    • 77953843784 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and MAP kinase and akt pathways in oral squamous cell carcinoma by genistein and biochanin A
    • Johnson TL, Lai MB, Lai JC and Bhushan A: Inhibition of cell proliferation and MAP kinase and akt pathways in oral squamous cell carcinoma by genistein and biochanin A. Evid Based Complement Alternat Med 7: 351-358, 2010.
    • (2010) Evid Based Complement Alternat Med , vol.7 , pp. 351-358
    • Johnson, T.L.1    Lai, M.B.2    Lai, J.C.3    Bhushan, A.4
  • 29
    • 84982279562 scopus 로고    scopus 로고
    • Development of mitochondrial permeability transition inhibitory agents: A novel drug target
    • Hellebrand EE and Varbiro G: Development of mitochondrial permeability transition inhibitory agents: a novel drug target. Drug Discov Ther 4: 54-61, 2010.
    • (2010) Drug Discov Ther , vol.4 , pp. 54-61
    • Hellebrand, E.E.1    Varbiro, G.2
  • 30
    • 71749121777 scopus 로고    scopus 로고
    • Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis
    • Tomasello F, Messina A, Lartigue L, et al: Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis. Cell Res 19: 1363-1376, 2009.
    • (2009) Cell Res , vol.19 , pp. 1363-1376
    • Tomasello, F.1    Messina, A.2    Lartigue, L.3
  • 31
    • 1842767259 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptotic cell death
    • Orrenius S: Mitochondrial regulation of apoptotic cell death. Toxicol Lett 149: 19-23, 2004.
    • (2004) Toxicol Lett , vol.149 , pp. 19-23
    • Orrenius, S.1
  • 32
    • 50449087729 scopus 로고    scopus 로고
    • Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK
    • Ling YH, Lin R and Perez-Soler R: Erlotinib induces mitochondrial- mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK. Mol Pharmacol 74: 793-806, 2008.
    • (2008) Mol Pharmacol , vol.74 , pp. 793-806
    • Ling, Y.H.1    Lin, R.2    Perez-Soler, R.3
  • 34
    • 0035146929 scopus 로고    scopus 로고
    • Life-or-death decisions by the Bcl-2 protein family
    • DOI 10.1016/S0968-0004(00)01740-0, PII S0968000400017400
    • Adams JM and Cory S: Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci 26: 61-66, 2001. (Pubitemid 32124712)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.1 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 35
    • 0037459081 scopus 로고    scopus 로고
    • Mitochondria: Releasing power for life and unleashing the machineries of death
    • DOI 10.1016/S0092-8674(03)00116-8
    • Newmeyer DD and Ferguson-Miller S: Mitochondria: releasing power for life and unleashing the machineries of death. Cell 112: 481-490, 2003. (Pubitemid 36263081)
    • (2003) Cell , vol.112 , Issue.4 , pp. 481-490
    • Newmeyer, D.D.1    Ferguson-Miller, S.2
  • 36
    • 0037401562 scopus 로고    scopus 로고
    • Cell death regulation by the Bcl-2 protein family in the mitochondria
    • Tsujimoto Y: Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 195: 158-167, 2003.
    • (2003) J Cell Physiol , vol.195 , pp. 158-167
    • Tsujimoto, Y.1
  • 38
    • 77951241220 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition
    • Kondo K, Obitsu S, Ohta S, Matsunami K, Otsuka H and Teshima R: Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition. J Biol Chem 285: 13079-13091, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 13079-13091
    • Kondo, K.1    Obitsu, S.2    Ohta, S.3    Matsunami, K.4    Otsuka, H.5    Teshima, R.6
  • 40
    • 54949132875 scopus 로고    scopus 로고
    • Bcl-2 family proteins and cancer
    • Yip KW and Reed JC: Bcl-2 family proteins and cancer. Oncogene 27: 6398-6406, 2008.
    • (2008) Oncogene , vol.27 , pp. 6398-6406
    • Yip, K.W.1    Reed, J.C.2
  • 41
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • DOI 10.1038/74994
    • Kroemer G and Reed JC: Mitochondrial control of cell death. Nat Med 6: 513-519, 2000. (Pubitemid 30305900)
    • (2000) Nature Medicine , vol.6 , Issue.5 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 42
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO: The biochemistry of apoptosis. Nature 407: 770-776, 2000.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 43
    • 34249978223 scopus 로고    scopus 로고
    • Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells
    • DOI 10.1007/s10495-007-0052-1
    • Paris C, Bertoglio J and Bréard J: Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells. Apoptosis 12: 1257-1267, 2007. (Pubitemid 46890382)
    • (2007) Apoptosis , vol.12 , Issue.7 , pp. 1257-1267
    • Paris, C.1    Bertoglio, J.2    Breard, J.3
  • 44
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • DOI 10.1126/science.1072682
    • Johnson GL and Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912, 2002. (Pubitemid 35425238)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 45
    • 0034671751 scopus 로고    scopus 로고
    • Requirement for ERK activation in cisplatin-induced apoptosis
    • DOI 10.1074/jbc.M004583200
    • Wang X, Martindale JL and Holbrook NJ: Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem 275: 39435-39443, 2000. (Pubitemid 32058968)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39435-39443
    • Wang, X.1    Martindale, J.L.2    Holbrook, N.J.3
  • 47
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • DOI 10.1038/35065000
    • Chang L and Karin M: Mammalian MAP kinase signalling cascades. Nature 410: 37-40, 2001. (Pubitemid 32225829)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 48
    • 3042549655 scopus 로고    scopus 로고
    • The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria
    • DOI 10.1016/j.febslet.2004.06.003, PII S0014579304007136
    • Tamura Y, Simizu S and Osada H: The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria. FEBS Lett 569: 249-255, 2004. (Pubitemid 38844627)
    • (2004) FEBS Letters , vol.569 , Issue.1-3 , pp. 249-255
    • Tamura, Y.1    Simizu, S.2    Osada, H.3
  • 49
    • 1442274808 scopus 로고    scopus 로고
    • p38 MAP kinase: A convergence point in cancer therapy
    • DOI 10.1016/j.molmed.2004.01.007, PII S1471491404000243
    • Olson JM and Hallahan AR: p38 MAP kinase: a convergence point in cancer therapy. Trends Mol Med 10: 125-129, 2004. (Pubitemid 38293348)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.3 , pp. 125-129
    • Olson, J.M.1    Hallahan, A.R.2
  • 50
    • 54249119561 scopus 로고    scopus 로고
    • JNK signaling in apoptosis
    • Dhanasekaran DN and Reddy EP: JNK signaling in apoptosis. Oncogene 27: 6245-6251, 2008.
    • (2008) Oncogene , vol.27 , pp. 6245-6251
    • Dhanasekaran, D.N.1    Reddy, E.P.2
  • 51
    • 41849116690 scopus 로고    scopus 로고
    • Roles of unphosphorylated STATs in signaling
    • DOI 10.1038/cr.2008.41, PII CR200841
    • Yang J and Stark GR: Roles of unphosphorylated STATs in signaling. Cell Res 18: 443-451, 2008. (Pubitemid 351498851)
    • (2008) Cell Research , vol.18 , Issue.4 , pp. 443-451
    • Yang, J.1    Stark, G.R.2
  • 53
    • 0038001179 scopus 로고    scopus 로고
    • ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: Implications towards sensitization to apoptosis
    • DOI 10.1038/sj.onc.1206598
    • Krasilnikov M, Ivanov VN, Dong J and Ronai Z: ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis. Oncogene 22: 4092-4101, 2003. (Pubitemid 36819649)
    • (2003) Oncogene , vol.22 , Issue.26 , pp. 4092-4101
    • Krasilnikov, M.1    Ivanov, V.N.2    Dong, J.3    Ronai, Z.4
  • 54
    • 79958193836 scopus 로고    scopus 로고
    • Testicular lumicrine factors regulate ERK, STAT, and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis
    • Xu B, Abdel-Fattah R, Yang L, Crenshaw SA, Black MB and Hinton BT: Testicular lumicrine factors regulate ERK, STAT, and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis. Biol Reprod 84: 1282-1291, 2011.
    • (2011) Biol Reprod , vol.84 , pp. 1282-1291
    • Xu, B.1    Abdel-Fattah, R.2    Yang, L.3    Crenshaw, S.A.4    Black, M.B.5    Hinton, B.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.