Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Chen, Huai Min ^a,b   Hsu, Jong Hau ^a,b   Liou, Shu Fen ^c   Chen, Tsan Ju ^a   Chen, Li Ying ^a   Chiu, Chaw Chi ^a,b   Yeh, Jwu Lai ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Apoptosis; Baicalein; Calcium; Lysophosphatidylcholine; Reactive oxygen species

Indexed keywords

BAICALEIN; CALCIUM; CASPASE 3; CASPASE 9; CYTOCHROME C; HOE 33342; LYSOPHOSPHATIDYLCHOLINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; DEATH; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEART INJURY; HEART MUSCLE CELL; HEART PROTECTION; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCUTELLARIA BAICALENSIS; STAINING; WESTERN BLOTTING; CONTROLLED STUDY; CYTOTOXICITY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; CELL LINE; CELL SURVIVAL; FLAVANONES; LYSOPHOSPHATIDYLCHOLINES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; RATS; REACTIVE OXYGEN SPECIES; SCUTELLARIA BAICALENSIS;

EID: 84903865321     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-233     Document Type: Article

References (24)

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