메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Cardiovascular effects of Glucagon-like peptide 1 (GLP-1) receptor agonists

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ALBIGLUTIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DULAGLUTIDE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; INCRETIN; INSULIN; INSULIN GLARGINE; LIRAGLUTIDE; LIXISENATIDE; METFORMIN; PHENTOLAMINE; PIOGLITAZONE; PLACEBO; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROPRANOLOL; RHO FACTOR; SEMAGLUTIDE; SITAGLIPTIN; VASCULAR CELL ADHESION MOLECULE 1; ANTIDIABETIC AGENT; GLP1R PROTEIN, HUMAN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR;

EID: 84964695799     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-014-0142-7     Document Type: Review
Times cited : (101)

References (79)
  • 1
    • 33644875549 scopus 로고    scopus 로고
    • Recent trends in cardiovascular complications among men and women with and without diabetes
    • Booth GL, Kapral MK, Fung K, Tu JV: Recent trends in cardiovascular complications among men and women with and without diabetes. Diabetes Care 2006, 29(1):32-7.
    • (2006) Diabetes Care , vol.29 , Issue.1 , pp. 32-37
    • Booth, G.L.1    Kapral, M.K.2    Fung, K.3    Tu, J.V.4
  • 2
    • 0347480402 scopus 로고    scopus 로고
    • Hyperglycemia as a cardiovascular risk factor
    • Haffner SJ, Cassells H: Hyperglycemia as a cardiovascular risk factor. Am J Med 2003, 115(Suppl 8A):6S-11S.
    • (2003) Am J Med , vol.115 , pp. 6S-11S
    • Haffner, S.J.1    Cassells, H.2
  • 3
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M: Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998, 339(4):229-34.
    • (1998) N Engl J Med , vol.339 , Issue.4 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Rönnemaa, T.3    Pyörälä, K.4    Laakso, M.5
  • 6
    • 0002294149 scopus 로고
    • New interpretation of oral glucose tolerance
    • McIntyre N, Holsworth DC, Turner DS: New interpretation of oral glucose tolerance. Lancet 1964, 2:20-21.
    • (1964) Lancet , vol.2 , pp. 20-21
    • McIntyre, N.1    Holsworth, D.C.2    Turner, D.S.3
  • 7
    • 0021864130 scopus 로고
    • New developments in the incretin concept
    • Creutzfeldt W, Ebert R: New developments in the incretin concept. Diabetologia 1985, 28:565-73.
    • (1985) Diabetologia , vol.28 , pp. 565-573
    • Creutzfeldt, W.1    Ebert, R.2
  • 8
    • 0022617246 scopus 로고
    • Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
    • Nauck M, Stockmann F, Ebert R, Creutzfeldt W: Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 1986, 29(1):46-52.
    • (1986) Diabetologia , vol.29 , Issue.1 , pp. 46-52
    • Nauck, M.1    Stockmann, F.2    Ebert, R.3    Creutzfeldt, W.4
  • 9
    • 84889877214 scopus 로고    scopus 로고
    • Improved glycemic control enhances the incretin effect in patients with type 2 diabetes
    • An Z, Prigeon RL, D'Alessio DA: Improved glycemic control enhances the incretin effect in patients with type 2 diabetes. J Clin Endocrinol Metab 2013, 98(12):4702-4708.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.12 , pp. 4702-4708
    • An, Z.1    Prigeon, R.L.2    D'Alessio, D.A.3
  • 10
    • 0033304603 scopus 로고    scopus 로고
    • The glucagon-like peptides
    • Kieffer TJ, Habener JF: The glucagon-like peptides. Endocr Rev 1999, 20(6):876-913.
    • (1999) Endocr Rev , vol.20 , Issue.6 , pp. 876-913
    • Kieffer, T.J.1    Habener, J.F.2
  • 11
    • 0028900758 scopus 로고
    • Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences
    • Wei Y, Mojsov S: Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett 1995, 358:219-24.
    • (1995) FEBS Lett , vol.358 , pp. 219-224
    • Wei, Y.1    Mojsov, S.2
  • 12
    • 34250635159 scopus 로고    scopus 로고
    • GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
    • Körner M, Stöckli M, Waser B, Reubi JC: GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. J Nucl Med 2007, 48:736-43.
    • (2007) J Nucl Med , vol.48 , pp. 736-743
    • Körner, M.1    Stöckli, M.2    Waser, B.3    Reubi, J.C.4
  • 13
    • 84901593760 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities
    • Lund A, Knop FK, Vilsbøll T: Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities. Eur J Intern Med 2014, 25(5):407-14.
    • (2014) Eur J Intern Med , vol.25 , Issue.5 , pp. 407-414
    • Lund, A.1    Knop, F.K.2    Vilsbøll, T.3
  • 14
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker DJ: Biology of incretins: GLP-1 and GIP. Gastroenterology 2007, 132(6):2131-57.
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 15
    • 84906927474 scopus 로고    scopus 로고
    • The role of glucagon on type 2 diabetes at a glance
    • Godoy-Matos AF: The role of glucagon on type 2 diabetes at a glance. Diabetol Metab Syndr 2014, 6(1):91.
    • (2014) Diabetol Metab Syndr , vol.6 , Issue.1 , pp. 91
    • Godoy-Matos, A.F.1
  • 17
    • 55649108863 scopus 로고    scopus 로고
    • Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
    • De Heer J, Rasmussen C, Coy DH, Holst JJ: Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. Diabetologia 2008, 51:2263-2270.
    • (2008) Diabetologia , vol.51 , pp. 2263-2270
    • De Heer, J.1    Rasmussen, C.2    Coy, D.H.3    Holst, J.J.4
  • 18
    • 33646394592 scopus 로고    scopus 로고
    • Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses
    • Little TJ, Pilichiewicz AN, Russo A, Phillips L, Jones KL, Nauck MA, Wishart J, Horowitz M, Feinle-Bisset C: Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses. J Clin Endocrinol Metab 2006, 91(5):1916-23.
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.5 , pp. 1916-1923
    • Little, T.J.1    Pilichiewicz, A.N.2    Russo, A.3    Phillips, L.4    Jones, K.L.5    Nauck, M.A.6    Wishart, J.7    Horowitz, M.8    Feinle-Bisset, C.9
  • 19
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ: Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998, 101(3):515-20.
    • (1998) J Clin Invest , vol.101 , Issue.3 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 21
    • 0029903111 scopus 로고    scopus 로고
    • Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
    • Ørskov C, Poulsen SS, Møller M, Holst JJ: Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996, 45:832-5.
    • (1996) Diabetes , vol.45 , pp. 832-835
    • Ørskov, C.1    Poulsen, S.S.2    Møller, M.3    Holst, J.J.4
  • 22
    • 33750093045 scopus 로고    scopus 로고
    • Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans
    • Pannacciulli N, Bunt JC, Koska J, Bogardus C, Krakoff J: Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans. Am J Clin Nutr 2006, 84:556-60.
    • (2006) Am J Clin Nutr , vol.84 , pp. 556-560
    • Pannacciulli, N.1    Bunt, J.C.2    Koska, J.3    Bogardus, C.4    Krakoff, J.5
  • 23
    • 84888433027 scopus 로고    scopus 로고
    • Glucose-stimulated insulin secretion: a newer perspective
    • Komatsu M, Takei M, Ishii H, Sato Y: Glucose-stimulated insulin secretion: a newer perspective. J Diabetes Investig 2013, 4(6):511-6.
    • (2013) J Diabetes Investig , vol.4 , Issue.6 , pp. 511-516
    • Komatsu, M.1    Takei, M.2    Ishii, H.3    Sato, Y.4
  • 25
    • 77951246517 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression
    • Cornu M, Modi H, Kawamori D, Kulkarni RN, Joffraud M, Thorens B: Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression. J Biol Chem 2010, 285(14):10538-45.
    • (2010) J Biol Chem , vol.285 , Issue.14 , pp. 10538-10545
    • Cornu, M.1    Modi, H.2    Kawamori, D.3    Kulkarni, R.N.4    Joffraud, M.5    Thorens, B.6
  • 26
    • 84906079407 scopus 로고    scopus 로고
    • Pleiotropic Effects of the Dipeptidylpeptidase-4 Inhibitors on the Cardiovascular System
    • Aroor AR, Sowers JR, Jia G, DeMarco VG: Pleiotropic Effects of the Dipeptidylpeptidase-4 Inhibitors on the Cardiovascular System. Am J Physiol Heart Circ Physiol 2014, 307(4):H477-H492.
    • (2014) Am J Physiol Heart Circ Physiol , vol.307 , Issue.4 , pp. H477-H492
    • Aroor, A.R.1    Sowers, J.R.2    Jia, G.3    DeMarco, V.G.4
  • 29
    • 84874605048 scopus 로고    scopus 로고
    • Pleiotropic effects of incretins
    • Gupta V: Pleiotropic effects of incretins. Indian J Endocrinol Metab 2012, 16(Suppl1):S47-S56.
    • (2012) Indian J Endocrinol Metab , vol.16 , pp. S47-S56
    • Gupta, V.1
  • 30
    • 84870606111 scopus 로고    scopus 로고
    • Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G proteincoupled receptor
    • Kirkpatrick A, Heo J, Abrol R, Goddard WA 3rd: Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G proteincoupled receptor. Proc Natl Acad Sci U S A 2012, 109(49):19988-93.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.49 , pp. 19988-19993
    • Kirkpatrick, A.1    Heo, J.2    Abrol, R.3    Goddard, W.A.4
  • 31
    • 0030013475 scopus 로고    scopus 로고
    • Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
    • Bullock BP, Heller RS, Habener JF: Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology 1996, 137(7):2968-2978.
    • (1996) Endocrinology , vol.137 , Issue.7 , pp. 2968-2978
    • Bullock, B.P.1    Heller, R.S.2    Habener, J.F.3
  • 32
    • 77950267745 scopus 로고    scopus 로고
    • Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor
    • Ban K, Kim KH, Cho CK, Sauvé M, Diamandis EP, Backx PH, Drucker DJ, Husain M: Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 2010, 151:1520-1531.
    • (2010) Endocrinology , vol.151 , pp. 1520-1531
    • Ban, K.1    Kim, K.H.2    Cho, C.K.3    Sauvé, M.4    Diamandis, E.P.5    Backx, P.H.6    Drucker, D.J.7    Husain, M.8
  • 33
    • 8544258807 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease
    • Nyström T, Gutniak MK, Zhang Q, Zhang F, Holst JJ, Ahrén B, Sjöholm A: Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol Endocrinol Metab 2004, 287:E1209-E1215.
    • (2004) Am J Physiol Endocrinol Metab , vol.287 , pp. E1209-E1215
    • Nyström, T.1    Gutniak, M.K.2    Zhang, Q.3    Zhang, F.4    Holst, J.J.5    Ahrén, B.6    Sjöholm, A.7
  • 34
    • 73949118948 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced upregulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
    • Ishibashi Y, Matsui T, Takeuchi M, Yamagishi S: Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced upregulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression. Biochem Biophys Res Commun 2010, 391:1405-1408.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1405-1408
    • Ishibashi, Y.1    Matsui, T.2    Takeuchi, M.3    Yamagishi, S.4
  • 35
    • 43249089631 scopus 로고    scopus 로고
    • Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways
    • Ban K, Noyan-Ashraf MH, Hoefer J, Bolz SS, Drucker DJ, Husain M: Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and-independent pathways. Circulation 2008, 117:2340-2350.
    • (2008) Circulation , vol.117 , pp. 2340-2350
    • Ban, K.1    Noyan-Ashraf, M.H.2    Hoefer, J.3    Bolz, S.S.4    Drucker, D.J.5    Husain, M.6
  • 36
    • 84901462249 scopus 로고    scopus 로고
    • Cardiovascular actions of incretin-based therapies
    • Ussher JR, Drucker DJ: Cardiovascular actions of incretin-based therapies. Circ Res 2014, 114(11):1788-803.
    • (2014) Circ Res , vol.114 , Issue.11 , pp. 1788-1803
    • Ussher, J.R.1    Drucker, D.J.2
  • 38
    • 0035980166 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes
    • Vila Petroff MG, Egan JM, Wang X, Sollott SJ: Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ Res 2001, 89:445-452.
    • (2001) Circ Res , vol.89 , pp. 445-452
    • Vila Petroff, M.G.1    Egan, J.M.2    Wang, X.3    Sollott, S.J.4
  • 39
    • 84884175820 scopus 로고    scopus 로고
    • Acting on hormone receptors with minimal side effect on cell proliferation: a timely challenge illustrated with GLP-1R and GPER
    • Gigoux V, Fourmy D: Acting on hormone receptors with minimal side effect on cell proliferation: a timely challenge illustrated with GLP-1R and GPER. Front Endocrinol 2013, 4:50.
    • (2013) Front Endocrinol , vol.4 , pp. 50
    • Gigoux, V.1    Fourmy, D.2
  • 40
    • 78651589386 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway
    • Xiao YF, Nikolskaya A, Jaye DA, Sigg DC: Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway. Cardiovasc Diabetol 2011, 10:6.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 6
    • Xiao, Y.F.1    Nikolskaya, A.2    Jaye, D.A.3    Sigg, D.C.4
  • 41
    • 78149478401 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
    • Rose BA, Force T, Wang Y: Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010, 90:1507-1546.
    • (2010) Physiol Rev , vol.90 , pp. 1507-1546
    • Rose, B.A.1    Force, T.2    Wang, Y.3
  • 42
    • 84885056255 scopus 로고    scopus 로고
    • Cardioprotective effects of exenatide against oxidative stress-induced injury
    • Chang G, Zhang D, Yu H, Zhang P, Wang Y, Zheng A, Qin S: Cardioprotective effects of exenatide against oxidative stress-induced injury. Int J Mol Med 2013, 32(5):1011-20.
    • (2013) Int J Mol Med , vol.32 , Issue.5 , pp. 1011-1020
    • Chang, G.1    Zhang, D.2    Yu, H.3    Zhang, P.4    Wang, Y.5    Zheng, A.6    Qin, S.7
  • 43
    • 84969323955 scopus 로고    scopus 로고
    • Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in rats
    • Shan PR, Xu WW, Huang ZQ, Pu J, Huang WJ: Protective role of retinoid X receptor in H9c2 cardiomyocytes from hypoxia/reoxygenation injury in rats. World J Emerg Med 2014, 5(2):122-7.
    • (2014) World J Emerg Med , vol.5 , Issue.2 , pp. 122-127
    • Shan, P.R.1    Xu, W.W.2    Huang, Z.Q.3    Pu, J.4    Huang, W.J.5
  • 45
    • 4344605042 scopus 로고    scopus 로고
    • Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy
    • Nikolaidis LA, Elahi D, Hentosz T, Doverspike A, Huerbin R, Zourelias L, Stolarski C, Shen YT, Shannon RP: Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation 2004, 110:955-961.
    • (2004) Circulation , vol.110 , pp. 955-961
    • Nikolaidis, L.A.1    Elahi, D.2    Hentosz, T.3    Doverspike, A.4    Huerbin, R.5    Zourelias, L.6    Stolarski, C.7    Shen, Y.T.8    Shannon, R.P.9
  • 47
    • 84858765882 scopus 로고    scopus 로고
    • Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow
    • Moberly SP, Berwick ZC, Kohr M, Svendsen M, Mather KJ, Tune JD: Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow. Exp Biol Med 2012, 237(3):334-42.
    • (2012) Exp Biol Med , vol.237 , Issue.3 , pp. 334-342
    • Moberly, S.P.1    Berwick, Z.C.2    Kohr, M.3    Svendsen, M.4    Mather, K.J.5    Tune, J.D.6
  • 48
    • 84879039617 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection
    • Zhao TC: Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection. Cardiovasc Diabetol 2013, 12:90.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 90
    • Zhao, T.C.1
  • 49
    • 33845293219 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
    • Sokos GG, Nikolaidis LA, Mankad S, Elahi D, Shannon RP: Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J Card Fail 2006, 12(9):694-699.
    • (2006) J Card Fail , vol.12 , Issue.9 , pp. 694-699
    • Sokos, G.G.1    Nikolaidis, L.A.2    Mankad, S.3    Elahi, D.4    Shannon, R.P.5
  • 51
    • 0028042205 scopus 로고
    • Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36 amide) in rats
    • Barragán JM, Rodríguez RE, Blázquez E: Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36 amide) in rats. Am J Physiol 1994, 266(3):E459-E466.
    • (1994) Am J Physiol , vol.266 , Issue.3 , pp. E459-E466
    • Barragán, J.M.1    Rodríguez, R.E.2    Blázquez, E.3
  • 52
    • 84873554686 scopus 로고    scopus 로고
    • Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis
    • Robinson LE, Holt TA, Rees K, Randeva HS, O'Hare JP: Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis. BMJ Open 2013, 3(1). doi:10.1136/ bmjopen-2012-001986.
    • (2013) BMJ Open , vol.3 , Issue.1
    • Robinson, L.E.1    Holt, T.A.2    Rees, K.3    Randeva, H.S.4    O'Hare, J.P.5
  • 53
    • 0141999599 scopus 로고    scopus 로고
    • Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects
    • Edwards CM, Todd JF, Ghatei MA, Bloom SR: Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects. Clin Sci 1998, 95(6):719-724.
    • (1998) Clin Sci , vol.95 , Issue.6 , pp. 719-724
    • Edwards, C.M.1    Todd, J.F.2    Ghatei, M.A.3    Bloom, S.R.4
  • 55
    • 77954384449 scopus 로고    scopus 로고
    • Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA-and PI3K/Akt-dependent pathways and requires GLP-1 receptor
    • Erdogdu O, Nathanson D, Sjöholm A, Nyström T, Zhang Q: Exendin-4 stimulates proliferation of human coronary artery endothelial cells through eNOS-, PKA-and PI3K/Akt-dependent pathways and requires GLP-1 receptor. Mol Cell Endocrinol 2010, 325:26-35.
    • (2010) Mol Cell Endocrinol , vol.325 , pp. 26-35
    • Erdogdu, O.1    Nathanson, D.2    Sjöholm, A.3    Nyström, T.4    Zhang, Q.5
  • 56
    • 84874931230 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism
    • Wang D, Luo P, Wang Y, Li W, Wang C, Sun D, Zhang R, Su T, Ma X, Zeng C, Wang H, Ren J, Cao F: Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism. Diabetes 2013, 62(5):1697-708.
    • (2013) Diabetes , vol.62 , Issue.5 , pp. 1697-1708
    • Wang, D.1    Luo, P.2    Wang, Y.3    Li, W.4    Wang, C.5    Sun, D.6    Zhang, R.7    Su, T.8    Ma, X.9    Zeng, C.10    Wang, H.11    Ren, J.12    Cao, F.13
  • 57
    • 84891591832 scopus 로고    scopus 로고
    • Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells
    • Batchuluun B, Inoguchi T, Sonoda N, Sasaki S, Inoue T, Fujimura Y, Miura D, Takayanagi R: Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells. Atherosclerosis 2014, 232(1):156-64.
    • (2014) Atherosclerosis , vol.232 , Issue.1 , pp. 156-164
    • Batchuluun, B.1    Inoguchi, T.2    Sonoda, N.3    Sasaki, S.4    Inoue, T.5    Fujimura, Y.6    Miura, D.7    Takayanagi, R.8
  • 59
    • 36148932551 scopus 로고    scopus 로고
    • Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride
    • Basu A, Charkoudian N, Schrage W, Rizza RA, Basu R, Joyner MJ: Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride. Am J Physiol Endocrinol Metab 2007, 293:E1289-E1295.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E1289-E1295
    • Basu, A.1    Charkoudian, N.2    Schrage, W.3    Rizza, R.A.4    Basu, R.5    Joyner, M.J.6
  • 60
    • 79956119675 scopus 로고    scopus 로고
    • The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an "endothelial resistance" to glucagon-like peptide 1 in diabetes
    • Ceriello A, Esposito K, Testa R, Bonfigli AR, Marra M, Giugliano D: The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an "endothelial resistance" to glucagon-like peptide 1 in diabetes. Diabetes Care 2011, 34:697-702.
    • (2011) Diabetes Care , vol.34 , pp. 697-702
    • Ceriello, A.1    Esposito, K.2    Testa, R.3    Bonfigli, A.R.4    Marra, M.5    Giugliano, D.6
  • 62
    • 84877317750 scopus 로고    scopus 로고
    • GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
    • Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, Simpson JA, Drucker DJ: GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure. Nat Med 2013, 19(5):567-75.
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 567-575
    • Kim, M.1    Platt, M.J.2    Shibasaki, T.3    Quaggin, S.E.4    Backx, P.H.5    Seino, S.6    Simpson, J.A.7    Drucker, D.J.8
  • 63
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    • Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R, Watada H: Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes 2010, 59:1030-1037.
    • (2010) Diabetes , vol.59 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3    Ebato, C.4    Goto, H.5    Nomiyama, T.6    Fujitani, Y.7    Hirose, T.8    Kawamori, R.9    Watada, H.10
  • 67
    • 84893424204 scopus 로고    scopus 로고
    • A glucagon-like peptide-1 analog liraglutide suppresses macrophage foam cell formation and atherosclerosis
    • S0196-9781
    • Tashiro Y, Sato K, Watanabe T, Nohtomi K, Terasaki M, Nagashima M, Hirano T: A glucagon-like peptide-1 analog liraglutide suppresses macrophage foam cell formation and atherosclerosis. Peptides 2014, S0196-9781(13):00431-2.
    • (2014) Peptides , Issue.13 , pp. 00431-00432
    • Tashiro, Y.1    Sato, K.2    Watanabe, T.3    Nohtomi, K.4    Terasaki, M.5    Nagashima, M.6    Hirano, T.7
  • 68
    • 67650057935 scopus 로고    scopus 로고
    • A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules
    • Liu H, Dear AE, Knudsen LB, Simpson RW: A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules. J Endocrinol 2009, 201:59-66.
    • (2009) J Endocrinol , vol.201 , pp. 59-66
    • Liu, H.1    Dear, A.E.2    Knudsen, L.B.3    Simpson, R.W.4
  • 69
    • 79951702236 scopus 로고    scopus 로고
    • Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other glucose-lowering therapies: a retrospective analysis of the LifeLink database
    • Best JH, Hoogwerf BJ, Herman WH, Pelletier EM, Smith DB, Wenten M, Hussein MA: Risk of cardiovascular disease events in patients with type 2 diabetes prescribed the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide twice daily or other glucose-lowering therapies: a retrospective analysis of the LifeLink database. Diabetes Care 2011, 34(1):90-5.
    • (2011) Diabetes Care , vol.34 , Issue.1 , pp. 90-95
    • Best, J.H.1    Hoogwerf, B.J.2    Herman, W.H.3    Pelletier, E.M.4    Smith, D.B.5    Wenten, M.6    Hussein, M.A.7
  • 70
    • 79952694840 scopus 로고    scopus 로고
    • Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes
    • Ratner R, Han J, Nicewarner D, Yushmanova I, Hoogwerf BJ, Shen L: Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes. Cardiovasc Diabetol 2011, 10:22.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 22
    • Ratner, R.1    Han, J.2    Nicewarner, D.3    Yushmanova, I.4    Hoogwerf, B.J.5    Shen, L.6
  • 71
    • 84862521094 scopus 로고    scopus 로고
    • Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety
    • Nathanson D, Ullman B, Löfström U, Hedman A, Frick M, Sjöholm A, Nyström T: Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety. Diabetologia 2012, 55(4):926-35.
    • (2012) Diabetologia , vol.55 , Issue.4 , pp. 926-935
    • Nathanson, D.1    Ullman, B.2    Löfström, U.3    Hedman, A.4    Frick, M.5    Sjöholm, A.6    Nyström, T.7
  • 72
    • 1442311383 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion
    • Nikolaidis LA, Mankad S, Sokos GG, Miske G, Shah A, Elahi D, Shannon RP: Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 2004, 109(8):962-5.
    • (2004) Circulation , vol.109 , Issue.8 , pp. 962-965
    • Nikolaidis, L.A.1    Mankad, S.2    Sokos, G.G.3    Miske, G.4    Shah, A.5    Elahi, D.6    Shannon, R.P.7
  • 73
    • 84883295202 scopus 로고    scopus 로고
    • Cardioprotective effects of exenatide in patients with ST-segmentelevation myocardial infarction undergoing primary percutaneous coronary intervention: results of exenatide myocardial protection in revascularization study
    • Woo JS, Kim W, Ha SJ, Kim JB, Kim SJ, Kim WS, Seon HJ, Kim KS: Cardioprotective effects of exenatide in patients with ST-segmentelevation myocardial infarction undergoing primary percutaneous coronary intervention: results of exenatide myocardial protection in revascularization study. Arterioscler Thromb Vasc Biol 2013, 33(9):2252-60.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.9 , pp. 2252-2260
    • Woo, J.S.1    Kim, W.2    Ha, S.J.3    Kim, J.B.4    Kim, S.J.5    Kim, W.S.6    Seon, H.J.7    Kim, K.S.8
  • 74
    • 84885300888 scopus 로고    scopus 로고
    • Liraglutide suppresses postprandial triglyceride and apolipoprotein B48 elevations after a fat-rich meal in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, cross-over trial
    • Hermansen K, Bækdal TA, Düring M, Pietraszek A, Mortensen LS, Jørgensen H, Flint A: Liraglutide suppresses postprandial triglyceride and apolipoprotein B48 elevations after a fat-rich meal in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, cross-over trial. Diab Obesity Metabol 2013, 15:1040-1048.
    • (2013) Diab Obesity Metabol , vol.15 , pp. 1040-1048
    • Hermansen, K.1    Bækdal, T.A.2    Düring, M.3    Pietraszek, A.4    Mortensen, L.S.5    Jørgensen, H.6    Flint, A.7
  • 75
    • 84875178118 scopus 로고    scopus 로고
    • Treatment of patients with type 2 diabetes with exenatide once weekly versus oral glucoselowering medications or insulin glargine: achievement of glycemic and cardiovascular goals
    • Meloni AR, DeYoung MB, Han J, Best JH, Grimm M: Treatment of patients with type 2 diabetes with exenatide once weekly versus oral glucoselowering medications or insulin glargine: achievement of glycemic and cardiovascular goals. Cardiovasc Diabetol 2013, 12:48.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 48
    • Meloni, A.R.1    DeYoung, M.B.2    Han, J.3    Best, J.H.4    Grimm, M.5
  • 76
    • 33646795007 scopus 로고    scopus 로고
    • Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts
    • Zhao T, Parikh P, Bhashyam S, Bolukoglu H, Poornima I, Shen YT, Shannon RP: Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther 2006, 317:1106-1113.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 1106-1113
    • Zhao, T.1    Parikh, P.2    Bhashyam, S.3    Bolukoglu, H.4    Poornima, I.5    Shen, Y.T.6    Shannon, R.P.7
  • 77
    • 77958052010 scopus 로고    scopus 로고
    • A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells
    • Hattori Y, Jojima T, Tomizawa A, Satoh H, Hattori S, Kasai K, Hayashi T: A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells. Diabetologia 2010, 53(10):2256-63.
    • (2010) Diabetologia , vol.53 , Issue.10 , pp. 2256-2263
    • Hattori, Y.1    Jojima, T.2    Tomizawa, A.3    Satoh, H.4    Hattori, S.5    Kasai, K.6    Hayashi, T.7
  • 78
    • 84857111888 scopus 로고    scopus 로고
    • Cardioprotection against ischaemia induced by dobutamine stress using glucagon-like peptide-1 in patients with coronary artery disease
    • Read PA, Khan FZ, Dutka DP: Cardioprotection against ischaemia induced by dobutamine stress using glucagon-like peptide-1 in patients with coronary artery disease. Heart 2012, 98(5):408-13.
    • (2012) Heart , vol.98 , Issue.5 , pp. 408-413
    • Read, P.A.1    Khan, F.Z.2    Dutka, D.P.3
  • 79
    • 84875385071 scopus 로고    scopus 로고
    • Treatment with exenatide once weekly or twice daily for 30 weeks is associated with changes in several cardiovascular risk markers
    • Chiquette E, Toth PP, Ramirez G, Cobble M, Chilton R: Treatment with exenatide once weekly or twice daily for 30 weeks is associated with changes in several cardiovascular risk markers. Vasc Health Risk Manag 2012, 8:621-9.
    • (2012) Vasc Health Risk Manag , vol.8 , pp. 621-629
    • Chiquette, E.1    Toth, P.P.2    Ramirez, G.3    Cobble, M.4    Chilton, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.