Panax quinquefolium saponin attenuates cardiomyocyte apoptosis and opening of the mitochondrial permeability transition pore in a rat model of ischemia/reperfusion

Cellular Physiology and Biochemistry

Volumn 34, Issue 4, 2014, Pages 1413-1426

  Li, Dong ^a,b,c   Liu, Mi ^b   Tao, Tian Qi ^b   Song, Dan Dan ^b   Liu, Xiu Hua ^b   Shi, Da Zhuo ^c  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c XIYUAN HOSPITAL   (China)

Author keywords

Apoptosis; Cardiomyocyte; Ischemia reperfusion; Mitochondrial permeability transition pore; Panax quinquefolium saponin

Indexed keywords

CARDIOVASCULAR AGENT; CASPASE 3; CASPASE 9; CREATINE KINASE MB; CYCLOSPORIN A; CYTOCHROME C; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PANAX QUINQUEFOLIUM SAPONIN; PLANT EXTRACT; PROTEIN BAX; SAPONIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CYCLOSPORIN; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; CYTOSOLIC FRACTION; ENDOPLASMIC RETICULUM STRESS; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION SWELLING; NONHUMAN; PANAX QUINQUEFOLIUS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; ANIMAL; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MYOCARDIAL REPERFUSION INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CYCLOSPORINE; CYTOCHROMES C; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SAPONINS;

EID: 84908654316     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366347     Document Type: Article

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