메뉴 건너뛰기




Volumn 7, Issue 25, 2016, Pages 38959-38972

Current perspectives between metabolic syndrome and cancer

Author keywords

Cancer risk; Hyperglycemia; Inflammation; Metabolic syndrome; Visceral adiposity

Indexed keywords

BETA CATENIN; C REACTIVE PROTEIN; ESTRADIOL; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; RAS PROTEIN; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR FOXO; TUMOR NECROSIS FACTOR ALPHA; ESTROGEN;

EID: 84978112720     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8341     Document Type: Review
Times cited : (85)

References (116)
  • 1
    • 84907876963 scopus 로고    scopus 로고
    • Relationship between chronic kidney disease and metabolic syndrome: current perspectives
    • Nashar K, Egan BM. Relationship between chronic kidney disease and metabolic syndrome: current perspectives. Diabetes Metab Syndr Obes. 2014; 7: 421-35.
    • (2014) Diabetes Metab Syndr Obes , vol.7 , pp. 421-435
    • Nashar, K.1    Egan, B.M.2
  • 3
    • 70350245011 scopus 로고    scopus 로고
    • Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
    • Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009; 120: 1640-5.
    • (2009) Circulation , vol.120 , pp. 1640-1645
    • Alberti, K.G.1    Eckel, R.H.2    Grundy, S.M.3    Zimmet, P.Z.4    Cleeman, J.I.5    Donato, K.A.6    Fruchart, J.C.7    James, W.P.8    Loria, C.M.9    Smith, S.C.10
  • 4
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    • Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA. 2002; 287: 356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 6
    • 4644279733 scopus 로고    scopus 로고
    • Increasing prevalence of the metabolic syndrome among U.S. adults
    • Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care. 2004; 27: 2444-2449.
    • (2004) Diabetes Care , vol.27 , pp. 2444-2449
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 8
    • 38149095747 scopus 로고    scopus 로고
    • Are there specific treatments for the metabolic syndrome?
    • Giuliano D, Ceriello A, Esposito K. Are there specific treatments for the metabolic syndrome? Am J Clin Nutr. 2008; 87: 8-11.
    • (2008) Am J Clin Nutr , vol.87 , pp. 8-11
    • Giuliano, D.1    Ceriello, A.2    Esposito, K.3
  • 16
    • 1642405087 scopus 로고    scopus 로고
    • The obesity epidemic, metabolic syndrome and future prevention strategies
    • James WTP, Rigby N, Leach R. The obesity epidemic, metabolic syndrome and future prevention strategies. Eur J Cardiovasc Prev Rehabil. 2004; 11: 3-8.
    • (2004) Eur J Cardiovasc Prev Rehabil , vol.11 , pp. 3-8
    • James, W.T.P.1    Rigby, N.2    Leach, R.3
  • 17
    • 77949653387 scopus 로고    scopus 로고
    • Symposium 1: overnutrition: consequences and solutions. Obesity and cancer risk
    • Key TJ, Spencer EA, Reeves GK. Symposium 1: overnutrition: consequences and solutions. Obesity and cancer risk. Proc Nutr Soc. 2010; 69: 86-90.
    • (2010) Proc Nutr Soc , vol.69 , pp. 86-90
    • Key, T.J.1    Spencer, E.A.2    Reeves, G.K.3
  • 18
    • 0942290570 scopus 로고    scopus 로고
    • Canadian Cancer Registries Epidemiology Research Group. Association of obesity and cancer risk in Canada
    • Pan SY, Johnson KC, Ugnat AM, Wen SW, Mao Y. Canadian Cancer Registries Epidemiology Research Group. Association of obesity and cancer risk in Canada. Am J Epidemiol. 2004; 159: 259-268.
    • (2004) Am J Epidemiol , vol.159 , pp. 259-268
    • Pan, S.Y.1    Johnson, K.C.2    Ugnat, A.M.3    Wen, S.W.4    Mao, Y.5
  • 19
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    • Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008; 371: 569-78.
    • (2008) Lancet , vol.371 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 20
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003; 348: 1625-38.
    • (2003) N Engl J Med , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 22
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • Wellen KE, Hotamisligil GS. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest. 2003; 112: 1785-1788.
    • (2003) J Clin Invest , vol.112 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 23
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr. 2004; 92: 347-55.
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 24
    • 33947653911 scopus 로고    scopus 로고
    • The metabolic syndrome: A high-risk state for cancer?
    • Cowey S, Hardy RW. The metabolic syndrome: A high-risk state for cancer?. Am J Pathol. 2006; 169: 1505-22.
    • (2006) Am J Pathol , vol.169 , pp. 1505-1522
    • Cowey, S.1    Hardy, R.W.2
  • 25
    • 79959243918 scopus 로고    scopus 로고
    • Glucose metabolism disorders and the risk of cancer
    • Piatkiewicz P, Czech A. Glucose metabolism disorders and the risk of cancer. Arch Immunol Ther Exp. 2011; 59: 215-230.
    • (2011) Arch Immunol Ther Exp , vol.59 , pp. 215-230
    • Piatkiewicz, P.1    Czech, A.2
  • 31
    • 27944453623 scopus 로고    scopus 로고
    • Angiogenic factors are elevated in overweight and obese individuals
    • Silha JV, Krsek M, Sucharda P, Murphy LJ. Angiogenic factors are elevated in overweight and obese individuals. Int J Obes (Lond). 2005; 29: 1308-14.
    • (2005) Int J Obes (Lond) , vol.29 , pp. 1308-1314
    • Silha, J.V.1    Krsek, M.2    Sucharda, P.3    Murphy, L.J.4
  • 32
    • 0345117960 scopus 로고    scopus 로고
    • Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects
    • Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Saito Y. Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects. Diabetologia. 2003; 46: 1483-8.
    • (2003) Diabetologia , vol.46 , pp. 1483-1488
    • Miyazawa-Hoshimoto, S.1    Takahashi, K.2    Bujo, H.3    Hashimoto, N.4    Saito, Y.5
  • 33
    • 62149144686 scopus 로고    scopus 로고
    • Combinatorial stem cell mobilization
    • Kolonin MG, Simmons PJ. Combinatorial stem cell mobilization. Nat Biotechnol. 2009; 27: 252-3.
    • (2009) Nat Biotechnol , vol.27 , pp. 252-253
    • Kolonin, M.G.1    Simmons, P.J.2
  • 34
    • 41549139755 scopus 로고    scopus 로고
    • Mesenchymal stem cells: revisiting history, concepts, and assays
    • Bianco P, Robey PG, Simmons PJ. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell. 2008; 2: 313-319.
    • (2008) Cell Stem Cell , vol.2 , pp. 313-319
    • Bianco, P.1    Robey, P.G.2    Simmons, P.J.3
  • 36
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 1997; 276: 71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 37
  • 38
    • 77955899564 scopus 로고    scopus 로고
    • The metabolic syndrome-an ongoing story
    • Duvnjak L, Duvnjak M. The metabolic syndrome-an ongoing story. J Physiol Pharmacol. 2009; 7: 19-24.
    • (2009) J Physiol Pharmacol , vol.7 , pp. 19-24
    • Duvnjak, L.1    Duvnjak, M.2
  • 39
    • 35948982621 scopus 로고    scopus 로고
    • The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction
    • Bergamini E, Cavallini G, Donati A, Gori Z. The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction. Ann N Y Acad Sci. 2007; 1114: 69-78.
    • (2007) Ann N Y Acad Sci , vol.1114 , pp. 69-78
    • Bergamini, E.1    Cavallini, G.2    Donati, A.3    Gori, Z.4
  • 40
    • 68349107603 scopus 로고    scopus 로고
    • Cukrzyca i zespoĺ metaboliczny
    • Szczeklik A (ed). Medycyna Praktyczna, Krakow
    • Sieradzki J. Cukrzyca i zespoĺ metaboliczny. In: Szczeklik A (ed) Choroby Wewnetrzne. Medycyna Praktyczna, Krakow, 2005, Vol. 1, pp 1179-1215.
    • (2005) Choroby Wewnetrzne , vol.1 , pp. 1179-1215
    • Sieradzki, J.1
  • 42
    • 84855328537 scopus 로고    scopus 로고
    • Signaling pathways governing tumor angiogenesis
    • Sakurai T, Kudo M. Signaling pathways governing tumor angiogenesis. Oncology. 2011; 1: 24-9.
    • (2011) Oncology , vol.1 , pp. 24-29
    • Sakurai, T.1    Kudo, M.2
  • 43
    • 84857640868 scopus 로고    scopus 로고
    • The insulin and insulin-like growth factor receptor family in neoplasia: an update
    • Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer. 2012; 12: 159-69.
    • (2012) Nat Rev Cancer , vol.12 , pp. 159-169
    • Pollak, M.1
  • 44
    • 84860001611 scopus 로고    scopus 로고
    • Interactions between bone marrow stromal microenvironment and B-chronic lymphocytic leukemia cells: any role for Notch, Wnt and Hh signaling pathways?
    • Seke Etet PF, Vecchio L, Nwabo Kamdje AH. Interactions between bone marrow stromal microenvironment and B-chronic lymphocytic leukemia cells: any role for Notch, Wnt and Hh signaling pathways? Cell Signal. 2012; 24: 1433-43.
    • (2012) Cell Signal , vol.24 , pp. 1433-1443
    • Seke Etet, P.F.1    Vecchio, L.2    Nwabo Kamdje, A.H.3
  • 45
    • 24644436798 scopus 로고    scopus 로고
    • Obesity, Insulin Resistance and Cancer Risk
    • Sun Ha J, Hee JK, Jakyoung L. Obesity, Insulin Resistance and Cancer Risk. Yonsei Med J. 2005; 46: 449-455.
    • (2005) Yonsei Med J , vol.46 , pp. 449-455
    • Sun Ha, J.1    Hee, J.K.2    Jakyoung, L.3
  • 46
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
    • Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004; 4: 579-91.
    • (2004) Nat Rev Cancer , vol.4 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 47
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009; 324: 1029-33.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 48
    • 34447513075 scopus 로고    scopus 로고
    • Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics
    • Airley RE, Mobasheri A. Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics. Chemotherapy. 2007; 53: 233-256.
    • (2007) Chemotherapy , vol.53 , pp. 233-256
    • Airley, R.E.1    Mobasheri, A.2
  • 49
    • 12944262229 scopus 로고    scopus 로고
    • Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
    • Macheda ML, Rogers S, Best JD. Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol. 2005; 202: 654-662.
    • (2005) J Cell Physiol , vol.202 , pp. 654-662
    • Macheda, M.L.1    Rogers, S.2    Best, J.D.3
  • 51
    • 33746930794 scopus 로고    scopus 로고
    • Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer
    • King A, Selak MA, Gottlieb E. Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. Oncogene. 2006; 25: 4675-4682.
    • (2006) Oncogene , vol.25 , pp. 4675-4682
    • King, A.1    Selak, M.A.2    Gottlieb, E.3
  • 53
    • 0034087024 scopus 로고    scopus 로고
    • Mammalian hexokinases and their abnormal expression in cancer
    • Smith TA. Mammalian hexokinases and their abnormal expression in cancer. Br J Biomed Sci. 2000; 57: 170-178.
    • (2000) Br J Biomed Sci , vol.57 , pp. 170-178
    • Smith, T.A.1
  • 56
    • 84929515530 scopus 로고    scopus 로고
    • Hyperglycemia promotes K-Ras-induced lung tumorigenesis through BASCs amplification
    • Micucci C, Orciari S, Catalano A. Hyperglycemia promotes K-Ras-induced lung tumorigenesis through BASCs amplification. PLoS One. 2014; 9: e105550.
    • (2014) PLoS One , vol.9
    • Micucci, C.1    Orciari, S.2    Catalano, A.3
  • 59
    • 78751557237 scopus 로고    scopus 로고
    • Diabetogenic glucose and insulin concentrations modulate transcriptome and protein levels involved in tumour cell migration, adhesion and proliferation
    • Masur K, Vetter C, Hinz A, Tomas N, Henrich H, Niggemann B, Zänker KS. Diabetogenic glucose and insulin concentrations modulate transcriptome and protein levels involved in tumour cell migration, adhesion and proliferation. Br J Cancer. 2011; 104: 345-52.
    • (2011) Br J Cancer , vol.104 , pp. 345-352
    • Masur, K.1    Vetter, C.2    Hinz, A.3    Tomas, N.4    Henrich, H.5    Niggemann, B.6    Zänker, K.S.7
  • 60
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • LeRoith D, Roberts CT.Jr. The insulin-like growth factor system and cancer. Cancer Lett. 2003; 195: 127-37.
    • (2003) Cancer Lett , vol.195 , pp. 127-137
    • LeRoith, D.1    Roberts, C.T.2
  • 61
    • 0034453098 scopus 로고    scopus 로고
    • The effects of insulin-like growth factors on tumorigenesis and neoplastic growth
    • Khandwala HM, McCutcheon IE, Flyvbjerg A, Friend KE. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev. 2000; 21: 215-44.
    • (2000) Endocr Rev , vol.21 , pp. 215-244
    • Khandwala, H.M.1    McCutcheon, I.E.2    Flyvbjerg, A.3    Friend, K.E.4
  • 62
    • 0842303519 scopus 로고    scopus 로고
    • Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells
    • Frasca F, Pandini G, Vigneri R, Goldfine ID. Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells. Breast Dis. 2003; 17: 73-89.
    • (2003) Breast Dis , vol.17 , pp. 73-89
    • Frasca, F.1    Pandini, G.2    Vigneri, R.3    Goldfine, I.D.4
  • 65
    • 0033585421 scopus 로고    scopus 로고
    • Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control study
    • Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X. Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control study. J Natl Cancer Inst. 1999; 91: 151-6.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 151-156
    • Yu, H.1    Spitz, M.R.2    Mistry, J.3    Gu, J.4    Hong, W.K.5    Wu, X.6
  • 66
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulinlike growth factor (IGF)-I and IGF-binding protein-3
    • Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, Stampfer MJ. Prospective study of colorectal cancer risk in men and plasma levels of insulinlike growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst. 1999; 91: 620-5.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 620-625
    • Ma, J.1    Pollak, M.N.2    Giovannucci, E.3    Chan, J.M.4    Tao, Y.5    Hennekens, C.H.6    Stampfer, M.J.7
  • 68
    • 0027172888 scopus 로고
    • Urokinase-type plasminogen activator: a paracrine factor regulating the bioavailability of IGFs in PA-III cell-induced osteoblastic metastases
    • Koutsilieris M, Frenette G, Lazure C, Lehoux JG, Govindan MV, Polychronakos C. Urokinase-type plasminogen activator: a paracrine factor regulating the bioavailability of IGFs in PA-III cell-induced osteoblastic metastases. Anticancer Research. 1993; 13: 481-486.
    • (1993) Anticancer Research , vol.13 , pp. 481-486
    • Koutsilieris, M.1    Frenette, G.2    Lazure, C.3    Lehoux, J.G.4    Govindan, M.V.5    Polychronakos, C.6
  • 69
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
    • Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Research. 1994; 54: 5474-5478.
    • (1994) Cancer Research , vol.54 , pp. 5474-5478
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3    Radmayr, C.4    Trapman, J.5    Hittmair, A.6    Bartsch, G.7    Klocker, H.8
  • 72
    • 79959745275 scopus 로고    scopus 로고
    • Relationships between insulin-like growth factor I and selected clinicomorphological parameters in colorectal cancer patients
    • Kuklinski A, Kamocki Z, Cepowicz D, Gryko M, Czyzewska J, Pawlak K, Kedra B. Relationships between insulin-like growth factor I and selected clinicomorphological parameters in colorectal cancer patients. Pol Przegl Chir. 2011; 83: 250-7.
    • (2011) Pol Przegl Chir , vol.83 , pp. 250-257
    • Kuklinski, A.1    Kamocki, Z.2    Cepowicz, D.3    Gryko, M.4    Czyzewska, J.5    Pawlak, K.6    Kedra, B.7
  • 77
    • 19944369418 scopus 로고    scopus 로고
    • A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer
    • Jiang Y, Wang L, Gong W, Wei D, Le X, Yao J, Ajani J, Abbruzzese JL, Huang S, Xie K. A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer. Clin Exp Metastasis. 2004; 21: 755-764.
    • (2004) Clin Exp Metastasis , vol.21 , pp. 755-764
    • Jiang, Y.1    Wang, L.2    Gong, W.3    Wei, D.4    Le, X.5    Yao, J.6    Ajani, J.7    Abbruzzese, J.L.8    Huang, S.9    Xie, K.10
  • 78
    • 0038491208 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma
    • Parker A, Cheville JC, Lohse C, Cerhan JR, Blute ML. Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma. J Urol. 2003; 170: 420-424.
    • (2003) J Urol , vol.170 , pp. 420-424
    • Parker, A.1    Cheville, J.C.2    Lohse, C.3    Cerhan, J.R.4    Blute, M.L.5
  • 83
    • 84885392560 scopus 로고    scopus 로고
    • Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer
    • Howe LR, Subbaramaiah K, Hudis CA, Dannenberg AJ. Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer. Clin. Cancer Res. 2013; 19: 6074-83.
    • (2013) Clin. Cancer Res , vol.19 , pp. 6074-6083
    • Howe, L.R.1    Subbaramaiah, K.2    Hudis, C.A.3    Dannenberg, A.J.4
  • 85
    • 80052767622 scopus 로고    scopus 로고
    • The link between the metabolic syndrome and cancer
    • Braun S, Bitton-Worms K, LeRoith D. The link between the metabolic syndrome and cancer. Int J Biol Sci. 2011; 7: 1003-15.
    • (2011) Int J Biol Sci , vol.7 , pp. 1003-1015
    • Braun, S.1    Bitton-Worms, K.2    LeRoith, D.3
  • 86
    • 84921345437 scopus 로고    scopus 로고
    • Obesity and cancer: local and systemic mechanisms
    • Iyengar NM, Hudis CA, Dannenberg AJ. Obesity and cancer: local and systemic mechanisms. Annu Rev Med. 2015; 66: 297-309.
    • (2015) Annu Rev Med , vol.66 , pp. 297-309
    • Iyengar, N.M.1    Hudis, C.A.2    Dannenberg, A.J.3
  • 89
    • 1342288777 scopus 로고    scopus 로고
    • C-reactive protein and the risk of incident colorectal cancer
    • Erlinger TP, Platz EA, Rifai N, Helzlsouer KJ. C-reactive protein and the risk of incident colorectal cancer. JAMA. 2004; 291: 585-90.
    • (2004) JAMA , vol.291 , pp. 585-590
    • Erlinger, T.P.1    Platz, E.A.2    Rifai, N.3    Helzlsouer, K.J.4
  • 92
    • 0033660593 scopus 로고    scopus 로고
    • Estrogen receptor-mediated processes in normal and cancer cells
    • Dickson RB, Stancel GM. Estrogen receptor-mediated processes in normal and cancer cells. J Natl Cancer Inst. Monogr. 2000; 27: 135-145.
    • (2000) J Natl Cancer Inst. Monogr , vol.27 , pp. 135-145
    • Dickson, R.B.1    Stancel, G.M.2
  • 94
    • 0023857383 scopus 로고
    • The dose-effect relationship between 'unopposed' estrogens and endometrial mitotic rate: its central role in explaining and predicting endometrial cancer
    • Key TJ, Pike MC. The dose-effect relationship between 'unopposed' estrogens and endometrial mitotic rate: its central role in explaining and predicting endometrial cancer. Br J Cancer. 1988; 57: 205-212.
    • (1988) Br J Cancer , vol.57 , pp. 205-212
    • Key, T.J.1    Pike, M.C.2
  • 95
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med. 2006; 354: 270-82.
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 97
    • 0037123341 scopus 로고    scopus 로고
    • Endogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies
    • Key T, Appleby P, Barnes I, Reeves G. Endogenous Hormones and Breast Cancer Collaborative Group. Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. J Natl Cancer Inst. 2002; 94: 606-16.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 606-616
    • Key, T.1    Appleby, P.2    Barnes, I.3    Reeves, G.4
  • 101
    • 0036970842 scopus 로고    scopus 로고
    • The role of the IGF system in cancer: from basic to clinical studies and clinical applications
    • Moschos SJ, Mantzoros CS. The role of the IGF system in cancer: from basic to clinical studies and clinical applications. Oncology. 2002; 63: 317-32.
    • (2002) Oncology , vol.63 , pp. 317-332
    • Moschos, S.J.1    Mantzoros, C.S.2
  • 102
    • 0024550730 scopus 로고
    • Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer
    • Yee D, Paik S, Lebovic GS, Marcus RR, Favoni RE, Cullen KJ, Lippman ME, Rosen N. Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol. 1989; 3: 509-17.
    • (1989) Mol Endocrinol , vol.3 , pp. 509-517
    • Yee, D.1    Paik, S.2    Lebovic, G.S.3    Marcus, R.R.4    Favoni, R.E.5    Cullen, K.J.6    Lippman, M.E.7    Rosen, N.8
  • 103
    • 84877313224 scopus 로고    scopus 로고
    • IGF-1R as an anti-cancer target-trials and tribulations
    • Chen HX, Sharon E. IGF-1R as an anti-cancer target-trials and tribulations. Chin J Cancer. 2013; 32: 242-52.
    • (2013) Chin J Cancer , vol.32 , pp. 242-252
    • Chen, H.X.1    Sharon, E.2
  • 105
    • 84866079242 scopus 로고    scopus 로고
    • The role of adiponectin in cancer: a review of current evidence
    • Dalamaga M, Diakopoulos KN, Mantzoros CS. The role of adiponectin in cancer: a review of current evidence. Endocr Rev. 2012; 33: 547-94.
    • (2012) Endocr Rev , vol.33 , pp. 547-594
    • Dalamaga, M.1    Diakopoulos, K.N.2    Mantzoros, C.S.3
  • 108
    • 0034614420 scopus 로고    scopus 로고
    • Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
    • El-Mir MY, Nogueira V, Fontaine E, Avéret N, Rigoulet M, Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem. 2000; 275: 223-8.
    • (2000) J Biol Chem , vol.275 , pp. 223-228
    • El-Mir, M.Y.1    Nogueira, V.2    Fontaine, E.3    Avéret, N.4    Rigoulet, M.5    Leverve, X.6
  • 110
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • Deberardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008; 7: 11-20.
    • (2008) Cell Metab , vol.7 , pp. 11-20
    • Deberardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 113
    • 33644614520 scopus 로고    scopus 로고
    • HIF 1 mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
    • Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF 1 mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006; 3: 177-185.
    • (2006) Cell Metab , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 114
    • 33644622570 scopus 로고    scopus 로고
    • HIF 1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF 1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006; 3: 187-197.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 115
    • 0346158376 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
    • Holness MJ, Sugden MC. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem Soc Trans. 2003; 31: 1143-1151.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1143-1151
    • Holness, M.J.1    Sugden, M.C.2
  • 116
    • 80052242132 scopus 로고    scopus 로고
    • Targeting cancer metabolism: a therapeutic window opens
    • Vander Heiden MG. Targeting cancer metabolism: a therapeutic window opens. Nat Rev Drug Discov. 2011; 10: 671-84.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 671-684
    • Vander Heiden, M.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.