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Volumn 46, Issue 11, 2003, Pages 1483-1488

Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects

Author keywords

Adipose tissue; Body fat distribution; Computed tomography; Diet therapy; Vascular endothelial growth factor

Indexed keywords

ANGIOGENIC FACTOR; HEPARIN; SEPHAROSE; STROMELYSIN; TRANSCRIPTION FACTOR ETS 1; VASCULOTROPIN;

EID: 0345117960     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1221-6     Document Type: Article
Times cited : (204)

References (31)
  • 1
    • 0029078449 scopus 로고
    • Regulation of the obese gene product (Leptin) in white adipose tissue and 3T3 adipocytes
    • MacDougald OA, Hwang CS, Fan H, Lane MD (1995) Regulation of the obese gene product (Leptin) in white adipose tissue and 3T3 adipocytes. Proc Natl Acad Sci USA 92:9034-9037
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9034-9037
    • MacDougald, O.A.1    Hwang, C.S.2    Fan, H.3    Lane, M.D.4
  • 3
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 4
    • 15844381594 scopus 로고    scopus 로고
    • Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
    • Shimomura I, Funahashi T, Takahashi M et al. (1996) Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med 2:800-803
    • (1996) Nat Med , vol.2 , pp. 800-803
    • Shimomura, I.1    Funahashi, T.2    Takahashi, M.3
  • 5
    • 0030735542 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
    • Mohamed-Ali V, Goodrick S, Rawesh A et al. (1997) Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocr Metab 82:4196-4200
    • (1997) J Clin Endocr Metab , vol.82 , pp. 4196-4200
    • Mohamed-Ali, V.1    Goodrick, S.2    Rawesh, A.3
  • 6
    • 0033678516 scopus 로고    scopus 로고
    • Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss
    • Bastard JP, Jardel C, Bruckert E et al. (2000) Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 85:3338-3342
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3338-3342
    • Bastard, J.P.1    Jardel, C.2    Bruckert, E.3
  • 7
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E et al. (1995) Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 8
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive-leptin concentrations in normal-weight and obese humans
    • Considine RV, Sinha MK, Heiman ML et al. (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295
    • (1996) N Engl J Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 9
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB (1995) The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 10
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-a in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995) Increased adipose tissue expression of tumor necrosis factor-a in human obesity and insulin resistance. J Clin Invest 95:2409-2415
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 14
    • 0019943007 scopus 로고
    • Relation of body fat distribution to metabolic complications of obesity
    • Kissebah AH, Vydelingum N, Murray R (1982) Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 54:254-260
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 254-260
    • Kissebah, A.H.1    Vydelingum, N.2    Murray, R.3
  • 15
    • 0027302580 scopus 로고
    • Association of body mass index and waist-hip circumference ratio with cardiovascular disease risk factors in Micronesian Nauruans
    • Hodge AM, Dowse GK, Zimmet PZ (1993) Association of body mass index and waist-hip circumference ratio with cardiovascular disease risk factors in Micronesian Nauruans. Int J Obes Relat Metab Disord 17:399-407
    • (1993) Int J Obes Relat Metab Disord , vol.17 , pp. 399-407
    • Hodge, A.M.1    Dowse, G.K.2    Zimmet, P.Z.3
  • 16
    • 0020513545 scopus 로고
    • A novel technique for the determination of body fat by computed tomography
    • Tokunaga K, Matsuzawa Y, Ishikawa K (1983) A novel technique for the determination of body fat by computed tomography. Int J Obes 7:437-745
    • (1983) Int J Obes , vol.7 , pp. 437-745
    • Tokunaga, K.1    Matsuzawa, Y.2    Ishikawa, K.3
  • 17
    • 0027169715 scopus 로고
    • Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen
    • Suzuki R, Watanabe S, Hirai Y et al. (1993) Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen. Am J Med 95:309-314
    • (1993) Am J Med , vol.95 , pp. 309-314
    • Suzuki, R.1    Watanabe, S.2    Hirai, Y.3
  • 18
  • 19
    • 0035988185 scopus 로고    scopus 로고
    • Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha?
    • Shibasaki M, Takahashi K, Itou T et al. (2002) Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha? Diabetologia 45:518-526
    • (2002) Diabetologia , vol.45 , pp. 518-526
    • Shibasaki, M.1    Takahashi, K.2    Itou, T.3
  • 20
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld, G, Cohen T, Gengrinovitch S, Poltrak Z (1999) Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13:9-22
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltrak, Z.4
  • 21
    • 0026660977 scopus 로고
    • Vascular endothelial growth factor: Regulation by cell differentiation and activated second messenger pathways
    • Claffey KP, Wilkison WO, Spiegelman BM (1992) Vascular endothelial growth factor: regulation by cell differentiation and activated second messenger pathways. J Biol Chem 267:16317-16322
    • (1992) J Biol Chem , vol.267 , pp. 16317-16322
    • Claffey, K.P.1    Wilkison, W.O.2    Spiegelman, B.M.3
  • 22
    • 0036185541 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptor, Flt-1, in the plasma of patients with coronary or peripheral atherosclerosis, or Type II diabetes
    • Lond
    • Blann AD, Belgore FM, McCollum CN, Silverman S, Lip PL, Lip GY (2002) Vascular endothelial growth factor and its receptor, Flt-1, in the plasma of patients with coronary or peripheral atherosclerosis, or Type II diabetes. Clin Sci (Lond) 102:187-194
    • (2002) Clin Sci , vol.102 , pp. 187-194
    • Blann, A.D.1    Belgore, F.M.2    McCollum, C.N.3    Silverman, S.4    Lip, P.L.5    Lip, G.Y.6
  • 23
    • 0034471549 scopus 로고    scopus 로고
    • Signal transduction and transcriptional regulation of angiogenesis
    • Sato Y, Abe M, Tanaka K et al. (2000) Signal transduction and transcriptional regulation of angiogenesis. Adv Exp Med Biol 476:109-115
    • (2000) Adv Exp Med Biol , vol.476 , pp. 109-115
    • Sato, Y.1    Abe, M.2    Tanaka, K.3
  • 24
    • 0031834984 scopus 로고    scopus 로고
    • Lipoprotein lipase mass and activity in post-heparin plasma from subjects with intra-abdominal visceral fat accumulation
    • Kobayashi J, Tashiro J, Murano S, Morisaki N, Saito Y. (1998) Lipoprotein lipase mass and activity in post-heparin plasma from subjects with intra-abdominal visceral fat accumulation. Clin Endocrinol 48:515-520
    • (1998) Clin Endocrinol , vol.48 , pp. 515-520
    • Kobayashi, J.1    Tashiro, J.2    Murano, S.3    Morisaki, N.4    Saito, Y.5
  • 25
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 26
    • 0032896330 scopus 로고    scopus 로고
    • Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas
    • Emoto M, Nishizawa Y, Maekawa K et al. (1999) Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 22:818-822
    • (1999) Diabetes Care , vol.22 , pp. 818-822
    • Emoto, M.1    Nishizawa, Y.2    Maekawa, K.3
  • 27
    • 0033961701 scopus 로고    scopus 로고
    • Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: Studies in subjects with various degrees of glucose tolerance and insulin sensitivity
    • Bonora E, Targher G, Alberiche M et al. (2000) Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 23:57-63
    • (2000) Diabetes Care , vol.23 , pp. 57-63
    • Bonora, E.1    Targher, G.2    Alberiche, M.3
  • 28
    • 0030229413 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, a multifunctional polypeptide
    • Stephan CC, Brock TA (1996) Vascular endothelial growth factor, a multifunctional polypeptide. PR Health Sci J 15:169-178
    • (1996) PR Health Sci J , vol.15 , pp. 169-178
    • Stephan, C.C.1    Brock, T.A.2
  • 29
    • 0036985699 scopus 로고    scopus 로고
    • Links Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
    • Ferrara N (2002) Links Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin Oncol 29:10-14
    • (2002) Semin Oncol , vol.29 , pp. 10-14
    • Ferrara, N.1
  • 30
    • 0026799293 scopus 로고
    • Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential
    • Sreenath T, Matrisian LM, Stetler-Stevenson W, Gattoni-Celli S, Pozzatti RO (1992) Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential. Cancer Res 52:4942-4947
    • (1992) Cancer Res , vol.52 , pp. 4942-4947
    • Sreenath, T.1    Matrisian, L.M.2    Stetler-Stevenson, W.3    Gattoni-Celli, S.4    Pozzatti, R.O.5
  • 31
    • 0036289135 scopus 로고    scopus 로고
    • Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3
    • 2002
    • Kanaki T, Bujo H, Mon S et al. (2002) Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3. Biochem Biophys Res Commun 2002 294:231-237
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 231-237
    • Kanaki, T.1    Bujo, H.2    Mon, S.3


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