메뉴 건너뛰기




Volumn 1, Issue 2, 2014, Pages 199-213

Fibroblast growth factor (FGF) signaling in development and skeletal diseases

Author keywords

Craniosynostosis; FGF signaling; Fibroblast growth factor; Fibroblast growth factor receptor; Genetics; Pathogenesis; Signal transduction; Skeletal development

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84978085683     PISSN: None     EISSN: 23523042     Source Type: Journal    
DOI: 10.1016/j.gendis.2014.09.005     Document Type: Review
Times cited : (183)

References (201)
  • 1
    • 0035081241 scopus 로고    scopus 로고
    • Fibroblast growth factors
    • REVIEWS3005
    • Ornitz D.M., Itoh N. Fibroblast growth factors. Genome Biol 2001, 2. REVIEWS3005.
    • (2001) Genome Biol , vol.2
    • Ornitz, D.M.1    Itoh, N.2
  • 2
    • 0000185608 scopus 로고    scopus 로고
    • Repair and Grafting of Bone
    • Elsevier Saunders, Philadelphia, PA, [Priciples], I.A. Seitz, C.M. Teven, R.R. Reid (Eds.)
    • Repair and Grafting of Bone. Plastic Surgery 2012, vol. 1. Elsevier Saunders, Philadelphia, PA, [Priciples]. I.A. Seitz, C.M. Teven, R.R. Reid (Eds.).
    • (2012) Plastic Surgery , vol.1
  • 3
    • 27744534898 scopus 로고    scopus 로고
    • Functions and regulations of fibroblast growth factor signaling during embryonic development
    • Thisse B., Thisse C. Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol Nov 15 2005, 287:390-402.
    • (2005) Dev Biol , vol.287 , pp. 390-402
    • Thisse, B.1    Thisse, C.2
  • 4
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: biology, pathophysiology and therapy
    • Beenken A., Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat Rev Drug Discov Mar 2009, 8:235-253.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 5
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N., Ornitz D.M. Evolution of the Fgf and Fgfr gene families. Trends Genet Nov 2004, 20:563-569.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 6
    • 0024375271 scopus 로고
    • Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor
    • Lee P.L., Johnson D.E., Cousens L.S., Fried V.A., Williams L.T. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science Jul 7 1989, 245:57-60.
    • (1989) Science , vol.245 , pp. 57-60
    • Lee, P.L.1    Johnson, D.E.2    Cousens, L.S.3    Fried, V.A.4    Williams, L.T.5
  • 7
    • 0025122589 scopus 로고
    • Diverse forms of a receptor for acidic and basic fibroblast growth factors
    • Johnson D.E., Lee P.L., Lu J., Williams L.T. Diverse forms of a receptor for acidic and basic fibroblast growth factors. Mol Cell Biol Sep 1990, 10:4728-4736.
    • (1990) Mol Cell Biol , vol.10 , pp. 4728-4736
    • Johnson, D.E.1    Lee, P.L.2    Lu, J.3    Williams, L.T.4
  • 9
    • 0028986809 scopus 로고
    • Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1
    • Wang F., Kan M., Yan G., Xu J., McKeehan W.L. Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1. J Biol Chem Apr 28 1995, 270:10231-10235.
    • (1995) J Biol Chem , vol.270 , pp. 10231-10235
    • Wang, F.1    Kan, M.2    Yan, G.3    Xu, J.4    McKeehan, W.L.5
  • 10
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
    • Zhang X., Ibrahimi O.A., Olsen S.K., Umemori H., Mohammadi M., Ornitz D.M. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem Jun 9 2006, 281:15694-15700.
    • (2006) J Biol Chem , vol.281 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3    Umemori, H.4    Mohammadi, M.5    Ornitz, D.M.6
  • 11
    • 0033961133 scopus 로고    scopus 로고
    • An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
    • De Moerlooze L., Spencer-Dene B., Revest J.M., Hajihosseini M., Rosewell I., Dickson C. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development Feb 2000, 127:483-492.
    • (2000) Development , vol.127 , pp. 483-492
    • De Moerlooze, L.1    Spencer-Dene, B.2    Revest, J.M.3    Hajihosseini, M.4    Rosewell, I.5    Dickson, C.6
  • 12
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: from development to cancer
    • Turner N., Grose R. Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer Feb 2010, 10:116-129.
    • (2010) Nat Rev Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 13
    • 18244368758 scopus 로고    scopus 로고
    • Genomic screening of fibroblast growth-factor receptor 2 reveals a wide spectrum of mutations in patients with syndromic craniosynostosis
    • Kan S.H., Elanko N., Johnson D., et al. Genomic screening of fibroblast growth-factor receptor 2 reveals a wide spectrum of mutations in patients with syndromic craniosynostosis. Am J Hum Genet Feb 2002, 70:472-486.
    • (2002) Am J Hum Genet , vol.70 , pp. 472-486
    • Kan, S.H.1    Elanko, N.2    Johnson, D.3
  • 14
    • 33846615392 scopus 로고    scopus 로고
    • Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia
    • Tekin M., Hismi B.O., Fitoz S., et al. Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia. Am J Hum Genet Feb 2007, 80:338-344.
    • (2007) Am J Hum Genet , vol.80 , pp. 338-344
    • Tekin, M.1    Hismi, B.O.2    Fitoz, S.3
  • 15
    • 33645381281 scopus 로고    scopus 로고
    • Mutations in different components of FGF signaling in LADD syndrome
    • Rohmann E., Brunner H.G., Kayserili H., et al. Mutations in different components of FGF signaling in LADD syndrome. Nat Genet Apr 2006, 38:414-417.
    • (2006) Nat Genet , vol.38 , pp. 414-417
    • Rohmann, E.1    Brunner, H.G.2    Kayserili, H.3
  • 16
    • 10344242939 scopus 로고    scopus 로고
    • Palifermin for oral mucositis after intensive therapy for hematologic cancers
    • Spielberger R., Stiff P., Bensinger W., et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med Dec 16 2004, 351:2590-2598.
    • (2004) N Engl J Med , vol.351 , pp. 2590-2598
    • Spielberger, R.1    Stiff, P.2    Bensinger, W.3
  • 17
    • 79959713140 scopus 로고    scopus 로고
    • Fibroblast growth factors and their receptors in cancer
    • Wesche J., Haglund K., Haugsten E.M. Fibroblast growth factors and their receptors in cancer. Biochem J Jul 15 2011, 437:199-213.
    • (2011) Biochem J , vol.437 , pp. 199-213
    • Wesche, J.1    Haglund, K.2    Haugsten, E.M.3
  • 18
    • 0030027488 scopus 로고    scopus 로고
    • Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
    • Mohammadi M., Dikic I., Sorokin A., Burgess W.H., Jaye M., Schlessinger J. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. Mol Cell Biol Mar 1996, 16:977-989.
    • (1996) Mol Cell Biol , vol.16 , pp. 977-989
    • Mohammadi, M.1    Dikic, I.2    Sorokin, A.3    Burgess, W.H.4    Jaye, M.5    Schlessinger, J.6
  • 19
    • 0025941527 scopus 로고
    • A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1
    • Mohammadi M., Honegger A.M., Rotin D., et al. A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1. Mol Cell Biol Oct 1991, 11:5068-5078.
    • (1991) Mol Cell Biol , vol.11 , pp. 5068-5078
    • Mohammadi, M.1    Honegger, A.M.2    Rotin, D.3
  • 21
    • 79956222121 scopus 로고    scopus 로고
    • Fibroblast growth factors: biology, function, and application for tissue regeneration
    • Yun Y.R., Won J.E., Jeon E., et al. Fibroblast growth factors: biology, function, and application for tissue regeneration. J Tissue Eng 2010, 2010:218142.
    • (2010) J Tissue Eng , vol.2010 , pp. 218142
    • Yun, Y.R.1    Won, J.E.2    Jeon, E.3
  • 22
    • 78149263789 scopus 로고    scopus 로고
    • FGF signalling: diverse roles during early vertebrate embryogenesis
    • Dorey K., Amaya E. FGF signalling: diverse roles during early vertebrate embryogenesis. Development Nov 2010, 137:3731-3742.
    • (2010) Development , vol.137 , pp. 3731-3742
    • Dorey, K.1    Amaya, E.2
  • 23
    • 0032740993 scopus 로고    scopus 로고
    • Modulating nuclear receptor function: may the phos be with you
    • Shao D., Lazar M.A. Modulating nuclear receptor function: may the phos be with you. J Clin Invest Jun 1999, 103:1617-1618.
    • (1999) J Clin Invest , vol.103 , pp. 1617-1618
    • Shao, D.1    Lazar, M.A.2
  • 24
    • 0037076329 scopus 로고    scopus 로고
    • FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl
    • Wong A., Lamothe B., Lee A., Schlessinger J., Lax I. FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl. Proc Natl Acad Sci U S A May 14 2002, 99:6684-6689.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6684-6689
    • Wong, A.1    Lamothe, B.2    Lee, A.3    Schlessinger, J.4    Lax, I.5
  • 25
    • 0036771763 scopus 로고    scopus 로고
    • The docking protein FRS2 alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors
    • Lax I., Wong A., Lamothe B., et al. The docking protein FRS2 alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors. Mol Cell Oct 2002, 10:709-719.
    • (2002) Mol Cell , vol.10 , pp. 709-719
    • Lax, I.1    Wong, A.2    Lamothe, B.3
  • 27
    • 2942744501 scopus 로고    scopus 로고
    • The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway
    • Lamothe B., Yamada M., Schaeper U., Birchmeier W., Lax I., Schlessinger J. The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway. Mol Cell Biol Jul 2004, 24:5657-5666.
    • (2004) Mol Cell Biol , vol.24 , pp. 5657-5666
    • Lamothe, B.1    Yamada, M.2    Schaeper, U.3    Birchmeier, W.4    Lax, I.5    Schlessinger, J.6
  • 28
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell Oct 13 2000, 103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 29
    • 33751113439 scopus 로고    scopus 로고
    • FGF signaling network in the gastrointestinal tract (review)
    • Katoh M. FGF signaling network in the gastrointestinal tract (review). Int J Oncol Jul 2006, 29:163-168.
    • (2006) Int J Oncol , vol.29 , pp. 163-168
    • Katoh, M.1
  • 30
    • 0032559228 scopus 로고    scopus 로고
    • Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
    • Hacohen N., Kramer S., Sutherland D., Hiromi Y., Krasnow M.A. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell Jan 23 1998, 92:253-263.
    • (1998) Cell , vol.92 , pp. 253-263
    • Hacohen, N.1    Kramer, S.2    Sutherland, D.3    Hiromi, Y.4    Krasnow, M.A.5
  • 31
    • 0033525895 scopus 로고    scopus 로고
    • Sprouty, an intracellular inhibitor of Ras signaling
    • Casci T., Vinos J., Freeman M. Sprouty, an intracellular inhibitor of Ras signaling. Cell Mar 5 1999, 96:655-665.
    • (1999) Cell , vol.96 , pp. 655-665
    • Casci, T.1    Vinos, J.2    Freeman, M.3
  • 32
    • 0035943595 scopus 로고    scopus 로고
    • The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3
    • Zhao Y., Zhang Z.Y. The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3. J Biol Chem Aug 24 2001, 276:32382-32391.
    • (2001) J Biol Chem , vol.276 , pp. 32382-32391
    • Zhao, Y.1    Zhang, Z.Y.2
  • 33
    • 0036173032 scopus 로고    scopus 로고
    • Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling
    • Furthauer M., Lin W., Ang S.L., Thisse B., Thisse C. Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling. Nat Cell Biol Feb 2002, 4:170-174.
    • (2002) Nat Cell Biol , vol.4 , pp. 170-174
    • Furthauer, M.1    Lin, W.2    Ang, S.L.3    Thisse, B.4    Thisse, C.5
  • 34
    • 2342483086 scopus 로고    scopus 로고
    • Promotion and attenuation of FGF signaling through the Ras-MAPK pathway
    • Tsang M., Dawid I.B. Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci STKE Apr 13 2004, 2004:pe17.
    • (2004) Sci STKE , vol.2004 , pp. pe17
    • Tsang, M.1    Dawid, I.B.2
  • 35
    • 0035316576 scopus 로고    scopus 로고
    • Cbl: many adaptations to regulate protein tyrosine kinases
    • Thien C.B., Langdon W.Y. Cbl: many adaptations to regulate protein tyrosine kinases. Nat Rev Mol Cell Biol Apr 2001, 2:294-307.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 294-307
    • Thien, C.B.1    Langdon, W.Y.2
  • 36
    • 84869481273 scopus 로고    scopus 로고
    • FGF Signalling in Vertebrate Development
    • Morgan & Claypool Life Sciences, San Rafael, CA
    • Pownall M.E., Isaacs H.V. FGF Signalling in Vertebrate Development. Developmental Biology 2010, Morgan & Claypool Life Sciences, San Rafael, CA.
    • (2010) Developmental Biology
    • Pownall, M.E.1    Isaacs, H.V.2
  • 37
    • 0035408007 scopus 로고    scopus 로고
    • FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak
    • Ciruna B., Rossant J. FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell Jul 2001, 1:37-49.
    • (2001) Dev Cell , vol.1 , pp. 37-49
    • Ciruna, B.1    Rossant, J.2
  • 38
    • 0030743776 scopus 로고    scopus 로고
    • Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak
    • Ciruna B.G., Schwartz L., Harpal K., Yamaguchi T.P., Rossant J. Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development Jul 1997, 124:2829-2841.
    • (1997) Development , vol.124 , pp. 2829-2841
    • Ciruna, B.G.1    Schwartz, L.2    Harpal, K.3    Yamaguchi, T.P.4    Rossant, J.5
  • 39
    • 0033565746 scopus 로고    scopus 로고
    • Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
    • Sun X., Meyers E.N., Lewandoski M., Martin G.R. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev Jul 15 1999, 13:1834-1846.
    • (1999) Genes Dev , vol.13 , pp. 1834-1846
    • Sun, X.1    Meyers, E.N.2    Lewandoski, M.3    Martin, G.R.4
  • 40
    • 0032947346 scopus 로고    scopus 로고
    • Fgf10 is essential for limb and lung formation
    • Sekine K., Ohuchi H., Fujiwara M., et al. Fgf10 is essential for limb and lung formation. Nat Genet Jan 1999, 21:138-141.
    • (1999) Nat Genet , vol.21 , pp. 138-141
    • Sekine, K.1    Ohuchi, H.2    Fujiwara, M.3
  • 41
    • 0036682468 scopus 로고    scopus 로고
    • Functions of FGF signalling from the apical ectodermal ridge in limb development
    • Sun X., Mariani F.V., Martin G.R. Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature Aug 1 2002, 418:501-508.
    • (2002) Nature , vol.418 , pp. 501-508
    • Sun, X.1    Mariani, F.V.2    Martin, G.R.3
  • 42
    • 0027411433 scopus 로고
    • Distribution of fibroblast growth factor 5 mRNA in the rat brain: an in situ hybridization study
    • Gomez-Pinilla F., Cotman C.W. Distribution of fibroblast growth factor 5 mRNA in the rat brain: an in situ hybridization study. Brain Res Mar 19 1993, 606:79-86.
    • (1993) Brain Res , vol.606 , pp. 79-86
    • Gomez-Pinilla, F.1    Cotman, C.W.2
  • 43
    • 0030916089 scopus 로고    scopus 로고
    • Transient expression of FGF-5 mRNA in the rat cerebellar cortex during post-natal development
    • Hattori Y., Miyake A., Mikami T., Ohta M., Itoh N. Transient expression of FGF-5 mRNA in the rat cerebellar cortex during post-natal development. Brain Res Mol Brain Res Jul 1997, 47:262-266.
    • (1997) Brain Res Mol Brain Res , vol.47 , pp. 262-266
    • Hattori, Y.1    Miyake, A.2    Mikami, T.3    Ohta, M.4    Itoh, N.5
  • 44
    • 0030971606 scopus 로고    scopus 로고
    • Spatially restricted expression of fibroblast growth factor-10 mRNA in the rat brain
    • Hattori Y., Yamasaki M., Konishi M., Itoh N. Spatially restricted expression of fibroblast growth factor-10 mRNA in the rat brain. Brain Res Mol Brain Res Jul 1997, 47:139-146.
    • (1997) Brain Res Mol Brain Res , vol.47 , pp. 139-146
    • Hattori, Y.1    Yamasaki, M.2    Konishi, M.3    Itoh, N.4
  • 45
    • 0029820043 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development
    • Smallwood P.M., Munoz-Sanjuan I., Tong P., et al. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A Sep 3 1996, 93:9850-9857.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9850-9857
    • Smallwood, P.M.1    Munoz-Sanjuan, I.2    Tong, P.3
  • 46
    • 0026448491 scopus 로고
    • Localization of acidic fibroblast growth factor in specific subcortical neuronal populations
    • Stock A., Kuzis K., Woodward W.R., Nishi R., Eckenstein F.P. Localization of acidic fibroblast growth factor in specific subcortical neuronal populations. J Neurosci Dec 1992, 12:4688-4700.
    • (1992) J Neurosci , vol.12 , pp. 4688-4700
    • Stock, A.1    Kuzis, K.2    Woodward, W.R.3    Nishi, R.4    Eckenstein, F.P.5
  • 47
    • 0026568913 scopus 로고
    • Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons
    • Woodward W.R., Nishi R., Meshul C.K., Williams T.E., Coulombe M., Eckenstein F.P. Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons. J Neurosci Jan 1992, 12:142-152.
    • (1992) J Neurosci , vol.12 , pp. 142-152
    • Woodward, W.R.1    Nishi, R.2    Meshul, C.K.3    Williams, T.E.4    Coulombe, M.5    Eckenstein, F.P.6
  • 48
    • 0034703619 scopus 로고    scopus 로고
    • Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
    • Yamashita T., Yoshioka M., Itoh N. Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain. Biochem Biophys Res Commun Oct 22 2000, 277:494-498.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 494-498
    • Yamashita, T.1    Yoshioka, M.2    Itoh, N.3
  • 49
    • 0037383088 scopus 로고    scopus 로고
    • Fibroblast growth factors as regulators of central nervous system development and function
    • Dono R. Fibroblast growth factors as regulators of central nervous system development and function. Am J Physiol Regul Integr Comp Physiol Apr 2003, 284:R867-R881.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , pp. R867-R881
    • Dono, R.1
  • 50
    • 0036746709 scopus 로고    scopus 로고
    • Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8
    • Yang X., Dormann D., Munsterberg A.E., Weijer C.J. Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. Dev Cell Sep 2002, 3:425-437.
    • (2002) Dev Cell , vol.3 , pp. 425-437
    • Yang, X.1    Dormann, D.2    Munsterberg, A.E.3    Weijer, C.J.4
  • 51
    • 0033973219 scopus 로고    scopus 로고
    • Chemotactic migration of mesencephalic neural crest cells in the mouse
    • Kubota Y., Ito K. Chemotactic migration of mesencephalic neural crest cells in the mouse. Dev Dyn Feb 2000, 217:170-179.
    • (2000) Dev Dyn , vol.217 , pp. 170-179
    • Kubota, Y.1    Ito, K.2
  • 52
    • 0034729912 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-dependent morphogenesis of the Drosophila mesoderm
    • Wilson R., Leptin M. Fibroblast growth factor receptor-dependent morphogenesis of the Drosophila mesoderm. Philos Trans R Soc Lond B Biol Sci Jul 29 2000, 355:891-895.
    • (2000) Philos Trans R Soc Lond B Biol Sci , vol.355 , pp. 891-895
    • Wilson, R.1    Leptin, M.2
  • 53
    • 0032766516 scopus 로고    scopus 로고
    • The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development
    • Montell D.J. The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development. Development Jun 1999, 126:3035-3046.
    • (1999) Development , vol.126 , pp. 3035-3046
    • Montell, D.J.1
  • 54
    • 13444263240 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling during early vertebrate development
    • Bottcher R.T., Niehrs C. Fibroblast growth factor signaling during early vertebrate development. Endocr Rev Feb 2005, 26:63-77.
    • (2005) Endocr Rev , vol.26 , pp. 63-77
    • Bottcher, R.T.1    Niehrs, C.2
  • 55
    • 0346655234 scopus 로고    scopus 로고
    • Roles of FGF receptors in mammalian development and congenital diseases
    • Coumoul X., Deng C.X. Roles of FGF receptors in mammalian development and congenital diseases. Birth Defects Res C Embryo Today Nov 2003, 69:286-304.
    • (2003) Birth Defects Res C Embryo Today , vol.69 , pp. 286-304
    • Coumoul, X.1    Deng, C.X.2
  • 56
    • 0035336772 scopus 로고    scopus 로고
    • Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning
    • Nutt S.L., Dingwell K.S., Holt C.E., Amaya E. Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning. Genes Dev May 1 2001, 15:1152-1166.
    • (2001) Genes Dev , vol.15 , pp. 1152-1166
    • Nutt, S.L.1    Dingwell, K.S.2    Holt, C.E.3    Amaya, E.4
  • 57
    • 0028598814 scopus 로고
    • Murine FGFR-1 is required for early postimplantation growth and axial organization
    • Deng C.X., Wynshaw-Boris A., Shen M.M., Daugherty C., Ornitz D.M., Leder P. Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev Dec 15 1994, 8:3045-3057.
    • (1994) Genes Dev , vol.8 , pp. 3045-3057
    • Deng, C.X.1    Wynshaw-Boris, A.2    Shen, M.M.3    Daugherty, C.4    Ornitz, D.M.5    Leder, P.6
  • 58
    • 0028582035 scopus 로고
    • Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
    • Yamaguchi T.P., Harpal K., Henkemeyer M., Rossant J. fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev Dec 15 1994, 8:3032-3044.
    • (1994) Genes Dev , vol.8 , pp. 3032-3044
    • Yamaguchi, T.P.1    Harpal, K.2    Henkemeyer, M.3    Rossant, J.4
  • 59
    • 0031149883 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-1 (FGFR-1) is essential for normal neural tube and limb development
    • Deng C., Bedford M., Li C., et al. Fibroblast growth factor receptor-1 (FGFR-1) is essential for normal neural tube and limb development. Dev Biol May 1 1997, 185:42-54.
    • (1997) Dev Biol , vol.185 , pp. 42-54
    • Deng, C.1    Bedford, M.2    Li, C.3
  • 60
    • 0033575364 scopus 로고    scopus 로고
    • Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH
    • Meyers E.N., Martin G.R. Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. Science Jul 16 1999, 285:403-406.
    • (1999) Science , vol.285 , pp. 403-406
    • Meyers, E.N.1    Martin, G.R.2
  • 61
    • 33845453906 scopus 로고    scopus 로고
    • Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish
    • Mizoguchi T., Izawa T., Kuroiwa A., Kikuchi Y. Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish. Dev Biol Dec 15 2006, 300:612-622.
    • (2006) Dev Biol , vol.300 , pp. 612-622
    • Mizoguchi, T.1    Izawa, T.2    Kuroiwa, A.3    Kikuchi, Y.4
  • 62
    • 70449535655 scopus 로고    scopus 로고
    • Downstream of FGF during mesoderm formation in Xenopus: the roles of Elk-1 and Egr-1
    • Nentwich O., Dingwell K.S., Nordheim A., Smith J.C. Downstream of FGF during mesoderm formation in Xenopus: the roles of Elk-1 and Egr-1. Dev Biol Dec 15 2009, 336:313-326.
    • (2009) Dev Biol , vol.336 , pp. 313-326
    • Nentwich, O.1    Dingwell, K.S.2    Nordheim, A.3    Smith, J.C.4
  • 63
    • 0033923749 scopus 로고    scopus 로고
    • Vertebrate mesendoderm induction and patterning
    • Kimelman D., Griffin K.J. Vertebrate mesendoderm induction and patterning. Curr Opin Genet Dev Aug 2000, 10:350-356.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 350-356
    • Kimelman, D.1    Griffin, K.J.2
  • 64
    • 0023105348 scopus 로고
    • Mesoderm induction in early Xenopus embryos by heparin-binding growth factors
    • Slack J.M., Darlington B.G., Heath J.K., Godsave S.F. Mesoderm induction in early Xenopus embryos by heparin-binding growth factors. Nature Mar 12-18 1987, 326:197-200.
    • (1987) Nature , vol.326 , pp. 197-200
    • Slack, J.M.1    Darlington, B.G.2    Heath, J.K.3    Godsave, S.F.4
  • 65
    • 0028012121 scopus 로고
    • Activin-mediated mesoderm induction requires FGF
    • Cornell R.A., Kimelman D. Activin-mediated mesoderm induction requires FGF. Development Feb 1994, 120:453-462.
    • (1994) Development , vol.120 , pp. 453-462
    • Cornell, R.A.1    Kimelman, D.2
  • 66
    • 43449107069 scopus 로고    scopus 로고
    • The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus
    • Fletcher R.B., Harland R.M. The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus. Dev Dyn May 2008, 237:1243-1254.
    • (2008) Dev Dyn , vol.237 , pp. 1243-1254
    • Fletcher, R.B.1    Harland, R.M.2
  • 67
    • 0025774136 scopus 로고
    • Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos
    • Amaya E., Musci T.J., Kirschner M.W. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell Jul 26 1991, 66:257-270.
    • (1991) Cell , vol.66 , pp. 257-270
    • Amaya, E.1    Musci, T.J.2    Kirschner, M.W.3
  • 68
    • 0030956930 scopus 로고    scopus 로고
    • Vertebrate neural induction: inducers, inhibitors, and a new synthesis
    • Wilson P.A., Hemmati-Brivanlou A. Vertebrate neural induction: inducers, inhibitors, and a new synthesis. Neuron May 1997, 18:699-710.
    • (1997) Neuron , vol.18 , pp. 699-710
    • Wilson, P.A.1    Hemmati-Brivanlou, A.2
  • 69
    • 0035512348 scopus 로고    scopus 로고
    • Neural induction: toward a unifying mechanism
    • Wilson S.I., Edlund T. Neural induction: toward a unifying mechanism. Nat Neurosci Nov 2001, (4 suppl):1161-1168.
    • (2001) Nat Neurosci , Issue.4 , pp. 1161-1168
    • Wilson, S.I.1    Edlund, T.2
  • 70
    • 70350465124 scopus 로고    scopus 로고
    • BMP inhibition initiates neural induction via FGF signaling and Zic genes
    • Marchal L., Luxardi G., Thome V., Kodjabachian L. BMP inhibition initiates neural induction via FGF signaling and Zic genes. Proc Natl Acad Sci U S A Oct 13 2009, 106:17437-17442.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 17437-17442
    • Marchal, L.1    Luxardi, G.2    Thome, V.3    Kodjabachian, L.4
  • 71
    • 0038057388 scopus 로고    scopus 로고
    • Split personalities: the agonistic antagonist Sprouty
    • Christofori G. Split personalities: the agonistic antagonist Sprouty. Nat Cell Biol May 2003, 5:377-379.
    • (2003) Nat Cell Biol , vol.5 , pp. 377-379
    • Christofori, G.1
  • 72
    • 0346594337 scopus 로고    scopus 로고
    • Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
    • Pera E.M., Ikeda A., Eivers E., De Robertis E.M. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev Dec 15 2003, 17:3023-3028.
    • (2003) Genes Dev , vol.17 , pp. 3023-3028
    • Pera, E.M.1    Ikeda, A.2    Eivers, E.3    De Robertis, E.M.4
  • 73
    • 63749132934 scopus 로고    scopus 로고
    • Characterisation of the fibroblast growth factor dependent transcriptome in early development
    • Branney P.A., Faas L., Steane S.E., Pownall M.E., Isaacs H.V. Characterisation of the fibroblast growth factor dependent transcriptome in early development. PLoS One 2009, 4:e4951.
    • (2009) PLoS One , vol.4 , pp. e4951
    • Branney, P.A.1    Faas, L.2    Steane, S.E.3    Pownall, M.E.4    Isaacs, H.V.5
  • 74
    • 13944274193 scopus 로고    scopus 로고
    • Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition
    • Delaune E., Lemaire P., Kodjabachian L. Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. Development Jan 2005, 132:299-310.
    • (2005) Development , vol.132 , pp. 299-310
    • Delaune, E.1    Lemaire, P.2    Kodjabachian, L.3
  • 75
    • 0032554782 scopus 로고    scopus 로고
    • Two phases of Hox gene regulation during early Xenopus development
    • Pownall M.E., Isaacs H.V., Slack J.M. Two phases of Hox gene regulation during early Xenopus development. Curr Biol May 21 1998, 8:673-676.
    • (1998) Curr Biol , vol.8 , pp. 673-676
    • Pownall, M.E.1    Isaacs, H.V.2    Slack, J.M.3
  • 76
    • 0029588307 scopus 로고
    • Basic FGF as an inducer of anteroposterior neural pattern
    • Doniach T. Basic FGF as an inducer of anteroposterior neural pattern. Cell Dec 29 1995, 83:1067-1070.
    • (1995) Cell , vol.83 , pp. 1067-1070
    • Doniach, T.1
  • 77
    • 0033832717 scopus 로고    scopus 로고
    • Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo
    • Umbhauer M., Penzo-Mendez A., Clavilier L., Boucaut J., Riou J. Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo. J Cell Sci Aug 2000, 113(Pt 16):2865-2875.
    • (2000) J Cell Sci , vol.113 , pp. 2865-2875
    • Umbhauer, M.1    Penzo-Mendez, A.2    Clavilier, L.3    Boucaut, J.4    Riou, J.5
  • 78
    • 0028850151 scopus 로고
    • Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern
    • Lamb T.M., Harland R.M. Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. Development Nov 1995, 121:3627-3636.
    • (1995) Development , vol.121 , pp. 3627-3636
    • Lamb, T.M.1    Harland, R.M.2
  • 79
    • 0034329542 scopus 로고    scopus 로고
    • Ras-mediated FGF signaling is required for the formation of posterior but not anterior neural tissue in Xenopus laevis
    • Ribisi S., Mariani F.V., Aamar E., Lamb T.M., Frank D., Harland R.M. Ras-mediated FGF signaling is required for the formation of posterior but not anterior neural tissue in Xenopus laevis. Dev Biol Nov 1 2000, 227:183-196.
    • (2000) Dev Biol , vol.227 , pp. 183-196
    • Ribisi, S.1    Mariani, F.V.2    Aamar, E.3    Lamb, T.M.4    Frank, D.5    Harland, R.M.6
  • 80
    • 0033555826 scopus 로고    scopus 로고
    • FGF is required for posterior neural patterning but not for neural induction
    • Holowacz T., Sokol S. FGF is required for posterior neural patterning but not for neural induction. Dev Biol Jan 15 1999, 205:296-308.
    • (1999) Dev Biol , vol.205 , pp. 296-308
    • Holowacz, T.1    Sokol, S.2
  • 81
    • 13344293677 scopus 로고
    • Caudalization of neural fate by tissue recombination and bFGF
    • Cox W.G., Hemmati-Brivanlou A. Caudalization of neural fate by tissue recombination and bFGF. Development Dec 1995, 121:4349-4358.
    • (1995) Development , vol.121 , pp. 4349-4358
    • Cox, W.G.1    Hemmati-Brivanlou, A.2
  • 82
    • 11144230079 scopus 로고    scopus 로고
    • How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development?
    • Sato T., Joyner A.L., Nakamura H. How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development?. Dev Growth Differ Dec 2004, 46:487-494.
    • (2004) Dev Growth Differ , vol.46 , pp. 487-494
    • Sato, T.1    Joyner, A.L.2    Nakamura, H.3
  • 83
    • 4644252454 scopus 로고    scopus 로고
    • The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
    • Sato T., Nakamura H. The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway. Development Sep 2004, 131:4275-4285.
    • (2004) Development , vol.131 , pp. 4275-4285
    • Sato, T.1    Nakamura, H.2
  • 84
    • 13944280317 scopus 로고    scopus 로고
    • Regulation of isthmic Fgf8 signal by sprouty2
    • Suzuki-Hirano A., Sato T., Nakamura H. Regulation of isthmic Fgf8 signal by sprouty2. Development Jan 2005, 132:257-265.
    • (2005) Development , vol.132 , pp. 257-265
    • Suzuki-Hirano, A.1    Sato, T.2    Nakamura, H.3
  • 85
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley P.H., Martinez S., Martin G.R. Midbrain development induced by FGF8 in the chick embryo. Nature Mar 7 1996, 380:66-68.
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 86
    • 28944438404 scopus 로고    scopus 로고
    • Modulating Hox gene functions during animal body patterning
    • Pearson J.C., Lemons D., McGinnis W. Modulating Hox gene functions during animal body patterning. Nat Rev Genet Dec 2005, 6:893-904.
    • (2005) Nat Rev Genet , vol.6 , pp. 893-904
    • Pearson, J.C.1    Lemons, D.2    McGinnis, W.3
  • 87
    • 0030478779 scopus 로고    scopus 로고
    • EFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus
    • Pownall M.E., Tucker A.S., Slack J.M., Isaacs H.V. eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus. Development Dec 1996, 122:3881-3892.
    • (1996) Development , vol.122 , pp. 3881-3892
    • Pownall, M.E.1    Tucker, A.S.2    Slack, J.M.3    Isaacs, H.V.4
  • 88
    • 0025260476 scopus 로고
    • Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid
    • Cho K.W., De Robertis E.M. Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid. Genes Dev Nov 1990, 4:1910-1916.
    • (1990) Genes Dev , vol.4 , pp. 1910-1916
    • Cho, K.W.1    De Robertis, E.M.2
  • 89
    • 0028837948 scopus 로고
    • Regulation of the Xenopus labial homeodomain genes, HoxA1 and HoxD1: activation by retinoids and peptide growth factors
    • Kolm P.J., Sive H.L. Regulation of the Xenopus labial homeodomain genes, HoxA1 and HoxD1: activation by retinoids and peptide growth factors. Dev Biol Jan 1995, 167:34-49.
    • (1995) Dev Biol , vol.167 , pp. 34-49
    • Kolm, P.J.1    Sive, H.L.2
  • 90
    • 0032146074 scopus 로고    scopus 로고
    • Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos
    • Partanen J., Schwartz L., Rossant J. Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev Aug 1 1998, 12:2332-2344.
    • (1998) Genes Dev , vol.12 , pp. 2332-2344
    • Partanen, J.1    Schwartz, L.2    Rossant, J.3
  • 91
    • 0036862406 scopus 로고    scopus 로고
    • Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups
    • Bel-Vialar S., Itasaki N., Krumlauf R. Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups. Development Nov 2002, 129:5103-5115.
    • (2002) Development , vol.129 , pp. 5103-5115
    • Bel-Vialar, S.1    Itasaki, N.2    Krumlauf, R.3
  • 92
    • 0032526962 scopus 로고    scopus 로고
    • Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3
    • Isaacs H.V., Pownall M.E., Slack J.M. Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3. EMBO J Jun 15 1998, 17:3413-3427.
    • (1998) EMBO J , vol.17 , pp. 3413-3427
    • Isaacs, H.V.1    Pownall, M.E.2    Slack, J.M.3
  • 93
    • 0027939990 scopus 로고
    • EFGF regulates Xbra expression during Xenopus gastrulation
    • Isaacs H.V., Pownall M.E., Slack J.M. eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J Oct 3 1994, 13:4469-4481.
    • (1994) EMBO J , vol.13 , pp. 4469-4481
    • Isaacs, H.V.1    Pownall, M.E.2    Slack, J.M.3
  • 94
    • 33751003542 scopus 로고    scopus 로고
    • FGF signal transduction and the regulation of Cdx gene expression
    • Keenan I.D., Sharrard R.M., Isaacs H.V. FGF signal transduction and the regulation of Cdx gene expression. Dev Biol Nov 15 2006, 299:478-488.
    • (2006) Dev Biol , vol.299 , pp. 478-488
    • Keenan, I.D.1    Sharrard, R.M.2    Isaacs, H.V.3
  • 95
    • 0028294478 scopus 로고
    • Dorsal-ventral differences in Xcad-3 expression in response to FGF-mediated induction in Xenopus
    • Northrop J.L., Kimelman D. Dorsal-ventral differences in Xcad-3 expression in response to FGF-mediated induction in Xenopus. Dev Biol Feb 1994, 161:490-503.
    • (1994) Dev Biol , vol.161 , pp. 490-503
    • Northrop, J.L.1    Kimelman, D.2
  • 96
    • 63849233073 scopus 로고    scopus 로고
    • Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis
    • Faas L., Isaacs H.V. Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis. Dev Dyn Apr 2009, 238:835-852.
    • (2009) Dev Dyn , vol.238 , pp. 835-852
    • Faas, L.1    Isaacs, H.V.2
  • 97
    • 0031028579 scopus 로고    scopus 로고
    • Neural induction and patterning in embryos deficient in FGF signaling
    • Godsave S.F., Durston A.J. Neural induction and patterning in embryos deficient in FGF signaling. Int J Dev Biol Feb 1997, 41:57-65.
    • (1997) Int J Dev Biol , vol.41 , pp. 57-65
    • Godsave, S.F.1    Durston, A.J.2
  • 98
    • 0026532352 scopus 로고
    • Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse
    • Niswander L., Martin G.R. Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development Mar 1992, 114:755-768.
    • (1992) Development , vol.114 , pp. 755-768
    • Niswander, L.1    Martin, G.R.2
  • 99
    • 2642595047 scopus 로고    scopus 로고
    • The roles of FGFs in the early development of vertebrate limbs
    • Martin G.R. The roles of FGFs in the early development of vertebrate limbs. Genes Dev Jun 1 1998, 12:1571-1586.
    • (1998) Genes Dev , vol.12 , pp. 1571-1586
    • Martin, G.R.1
  • 100
    • 0035427231 scopus 로고    scopus 로고
    • Vertebrate limb development - the early stages in chick and mouse
    • Tickle C., Munsterberg A. Vertebrate limb development - the early stages in chick and mouse. Curr Opin Genet Dev Aug 2001, 11:476-481.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 476-481
    • Tickle, C.1    Munsterberg, A.2
  • 101
    • 0031885801 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
    • Xu X., Weinstein M., Li C., et al. Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development Feb 1998, 125:753-765.
    • (1998) Development , vol.125 , pp. 753-765
    • Xu, X.1    Weinstein, M.2    Li, C.3
  • 102
    • 0030790518 scopus 로고    scopus 로고
    • The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
    • Ohuchi H., Nakagawa T., Yamamoto A., et al. The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor. Development Jun 1997, 124:2235-2244.
    • (1997) Development , vol.124 , pp. 2235-2244
    • Ohuchi, H.1    Nakagawa, T.2    Yamamoto, A.3
  • 103
    • 0029328540 scopus 로고
    • A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth
    • Mahmood R., Bresnick J., Hornbruch A., et al. A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr Biol Jul 1 1995, 5:797-806.
    • (1995) Curr Biol , vol.5 , pp. 797-806
    • Mahmood, R.1    Bresnick, J.2    Hornbruch, A.3
  • 104
    • 0029944234 scopus 로고    scopus 로고
    • Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb
    • Vogel A., Rodriguez C., Izpisua-Belmonte J.C. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development Jun 1996, 122:1737-1750.
    • (1996) Development , vol.122 , pp. 1737-1750
    • Vogel, A.1    Rodriguez, C.2    Izpisua-Belmonte, J.C.3
  • 105
    • 0030034731 scopus 로고    scopus 로고
    • Roles for FGF8 in the induction, initiation, and maintenance of chick limb development
    • Crossley P.H., Minowada G., MacArthur C.A., Martin G.R. Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell Jan 12 1996, 84:127-136.
    • (1996) Cell , vol.84 , pp. 127-136
    • Crossley, P.H.1    Minowada, G.2    MacArthur, C.A.3    Martin, G.R.4
  • 106
    • 0029790405 scopus 로고    scopus 로고
    • The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions
    • Ros M.A., Lopez-Martinez A., Simandl B.K., et al. The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development Aug 1996, 122:2319-2330.
    • (1996) Development , vol.122 , pp. 2319-2330
    • Ros, M.A.1    Lopez-Martinez, A.2    Simandl, B.K.3
  • 107
    • 0030438565 scopus 로고    scopus 로고
    • Functions of fibroblast growth factors in vertebrate development
    • Goldfarb M. Functions of fibroblast growth factors in vertebrate development. Cytokine Growth Factor Rev Dec 1996, 7:311-325.
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 311-325
    • Goldfarb, M.1
  • 108
    • 41649095548 scopus 로고    scopus 로고
    • FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis
    • Yu K., Ornitz D.M. FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis. Development Feb 2008, 135:483-491.
    • (2008) Development , vol.135 , pp. 483-491
    • Yu, K.1    Ornitz, D.M.2
  • 109
    • 33645130993 scopus 로고    scopus 로고
    • FGF signalling in craniofacial development and developmental disorders
    • Nie X., Luukko K., Kettunen P. FGF signalling in craniofacial development and developmental disorders. Oral Dis Mar 2006, 12:102-111.
    • (2006) Oral Dis , vol.12 , pp. 102-111
    • Nie, X.1    Luukko, K.2    Kettunen, P.3
  • 110
    • 0035229725 scopus 로고    scopus 로고
    • Genetic control of the cell proliferation-differentiation balance in the developing skull vault: roles of fibroblast growth factor receptor signalling pathways
    • discussion 116-121
    • Morriss-Kay G.M., Iseki S., Johnson D. Genetic control of the cell proliferation-differentiation balance in the developing skull vault: roles of fibroblast growth factor receptor signalling pathways. Novartis Found Symp 2001, 232:102-116. discussion 116-121.
    • (2001) Novartis Found Symp , vol.232 , pp. 102-116
    • Morriss-Kay, G.M.1    Iseki, S.2    Johnson, D.3
  • 111
    • 79955002353 scopus 로고    scopus 로고
    • FGF signaling in craniofacial biological control and pathological craniofacial development
    • Hatch N.E. FGF signaling in craniofacial biological control and pathological craniofacial development. Crit Rev Eukaryot Gene Expr 2010, 20:295-311.
    • (2010) Crit Rev Eukaryot Gene Expr , vol.20 , pp. 295-311
    • Hatch, N.E.1
  • 112
    • 0030769180 scopus 로고    scopus 로고
    • Craniosynostosis: genes and mechanisms
    • Wilkie A.O. Craniosynostosis: genes and mechanisms. Hum Mol Genet 1997, 6:1647-1656.
    • (1997) Hum Mol Genet , vol.6 , pp. 1647-1656
    • Wilkie, A.O.1
  • 113
  • 114
    • 0036061947 scopus 로고    scopus 로고
    • Regulation of human cranial osteoblast phenotype by FGF-2, FGFR-2 and BMP-2 signaling
    • Marie P.J., Debiais F., Hay E. Regulation of human cranial osteoblast phenotype by FGF-2, FGFR-2 and BMP-2 signaling. Histol Histopathol 2002, 17:877-885.
    • (2002) Histol Histopathol , vol.17 , pp. 877-885
    • Marie, P.J.1    Debiais, F.2    Hay, E.3
  • 115
    • 0031922720 scopus 로고    scopus 로고
    • BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development
    • Kim H.J., Rice D.P., Kettunen P.J., Thesleff I.F.G.F.- BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development. Development Apr 1998, 125:1241-1251.
    • (1998) Development , vol.125 , pp. 1241-1251
    • Kim, H.J.1    Rice, D.P.2    Kettunen, P.J.3    Thesleff, I.F.G.F.-4
  • 116
    • 0034106166 scopus 로고    scopus 로고
    • Integration of FGF and TWIST in calvarial bone and suture development
    • Rice D.P., Aberg T., Chan Y., et al. Integration of FGF and TWIST in calvarial bone and suture development. Development May 2000, 127:1845-1855.
    • (2000) Development , vol.127 , pp. 1845-1855
    • Rice, D.P.1    Aberg, T.2    Chan, Y.3
  • 117
    • 0020624879 scopus 로고
    • The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues
    • Noden D.M. The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues. Dev Biol Mar 1983, 96:144-165.
    • (1983) Dev Biol , vol.96 , pp. 144-165
    • Noden, D.M.1
  • 118
    • 0022965698 scopus 로고
    • Origins and patterning of craniofacial mesenchymal tissues
    • Noden D.M. Origins and patterning of craniofacial mesenchymal tissues. J Craniofac Genet Dev Biol Suppl 1986, 2:15-31.
    • (1986) J Craniofac Genet Dev Biol Suppl , vol.2 , pp. 15-31
    • Noden, D.M.1
  • 119
    • 0014894893 scopus 로고
    • Histochemical behavior of Paneth's cells in Central American bat species with varying nutritional habits. Results of the 1st Cuban-German "Alexander-von-Humbolt" expedition 1967-68. 4
    • Schaaf P. Histochemical behavior of Paneth's cells in Central American bat species with varying nutritional habits. Results of the 1st Cuban-German "Alexander-von-Humbolt" expedition 1967-68. 4. Anat Anz 1970, 126:275-277.
    • (1970) Anat Anz , vol.126 , pp. 275-277
    • Schaaf, P.1
  • 120
    • 0023127230 scopus 로고
    • Mapping of the early neural primordium in quail-chick chimeras. II. The prosencephalic neural plate and neural folds: implications for the genesis of cephalic human congenital abnormalities
    • Couly G.F., Le Douarin N.M. Mapping of the early neural primordium in quail-chick chimeras. II. The prosencephalic neural plate and neural folds: implications for the genesis of cephalic human congenital abnormalities. Dev Bio Mar 1987, 120:198-214.
    • (1987) Dev Bio , vol.120 , pp. 198-214
    • Couly, G.F.1    Le Douarin, N.M.2
  • 121
    • 0026530822 scopus 로고
    • The developmental fate of the cephalic mesoderm in quail-chick chimeras
    • Couly G.F., Coltey P.M., Le Douarin N.M. The developmental fate of the cephalic mesoderm in quail-chick chimeras. Development Jan 1992, 114:1-15.
    • (1992) Development , vol.114 , pp. 1-15
    • Couly, G.F.1    Coltey, P.M.2    Le Douarin, N.M.3
  • 122
    • 0027415509 scopus 로고
    • The triple origin of skull in higher vertebrates: a study in quail-chick chimeras
    • Couly G.F., Coltey P.M., Le Douarin N.M. The triple origin of skull in higher vertebrates: a study in quail-chick chimeras. Development Feb 1993, 117:409-429.
    • (1993) Development , vol.117 , pp. 409-429
    • Couly, G.F.1    Coltey, P.M.2    Le Douarin, N.M.3
  • 123
    • 0031406026 scopus 로고    scopus 로고
    • The origins of the neural crest. Part I: embryonic induction
    • Baker C.V., Bronner-Fraser M. The origins of the neural crest. Part I: embryonic induction. Mech Dev Dec 1997, 69:3-11.
    • (1997) Mech Dev , vol.69 , pp. 3-11
    • Baker, C.V.1    Bronner-Fraser, M.2
  • 124
    • 0037081282 scopus 로고    scopus 로고
    • Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction
    • Villanueva S., Glavic A., Ruiz P., Mayor R. Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction. Dev Biol Jan 15 2002, 241:289-301.
    • (2002) Dev Biol , vol.241 , pp. 289-301
    • Villanueva, S.1    Glavic, A.2    Ruiz, P.3    Mayor, R.4
  • 125
    • 0041669583 scopus 로고    scopus 로고
    • Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals
    • Monsoro-Burq A.H., Fletcher R.B., Harland R.M. Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals. Development Jul 2003, 130:3111-3124.
    • (2003) Development , vol.130 , pp. 3111-3124
    • Monsoro-Burq, A.H.1    Fletcher, R.B.2    Harland, R.M.3
  • 126
    • 13344285959 scopus 로고    scopus 로고
    • Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction
    • Monsoro-Burq A.H., Wang E., Harland R. Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction. Dev Cell Feb 2005, 8:167-178.
    • (2005) Dev Cell , vol.8 , pp. 167-178
    • Monsoro-Burq, A.H.1    Wang, E.2    Harland, R.3
  • 127
    • 0035145132 scopus 로고    scopus 로고
    • Expression of members of the Fgf family and their receptors during midfacial development
    • Bachler M., Neubuser A. Expression of members of the Fgf family and their receptors during midfacial development. Mech Dev Feb 2001, 100:313-316.
    • (2001) Mech Dev , vol.100 , pp. 313-316
    • Bachler, M.1    Neubuser, A.2
  • 128
    • 0032170311 scopus 로고    scopus 로고
    • Spatio-temporal expression of FGFR 1, 2 and 3 genes during human embryo-fetal ossification
    • Delezoide A.L., Benoist-Lasselin C., Legeai-Mallet L., et al. Spatio-temporal expression of FGFR 1, 2 and 3 genes during human embryo-fetal ossification. Mech Dev Sep 1998, 77:19-30.
    • (1998) Mech Dev , vol.77 , pp. 19-30
    • Delezoide, A.L.1    Benoist-Lasselin, C.2    Legeai-Mallet, L.3
  • 129
    • 0033662265 scopus 로고    scopus 로고
    • Cranial sutures as intramembranous bone growth sites
    • Opperman L.A. Cranial sutures as intramembranous bone growth sites. Dev Dyn Dec 2000, 219:472-485.
    • (2000) Dev Dyn , vol.219 , pp. 472-485
    • Opperman, L.A.1
  • 130
    • 0033373550 scopus 로고    scopus 로고
    • Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault
    • Iseki S., Wilkie A.O., Morriss-Kay G.M. Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault. Development Dec 1999, 126:5611-5620.
    • (1999) Development , vol.126 , pp. 5611-5620
    • Iseki, S.1    Wilkie, A.O.2    Morriss-Kay, G.M.3
  • 131
    • 0001930874 scopus 로고
    • The structure and development of cranial and facial sutures
    • Pritchard J.J., Scott J.H., Girgis F.G. The structure and development of cranial and facial sutures. J Anat Jan 1956, 90:73-86.
    • (1956) J Anat , vol.90 , pp. 73-86
    • Pritchard, J.J.1    Scott, J.H.2    Girgis, F.G.3
  • 132
    • 0031666099 scopus 로고    scopus 로고
    • Dura mater maintains rat cranial sutures invitro by regulating suture cell proliferation and collagen production
    • Opperman L.A., Chhabra A., Nolen A.A., Bao Y., Ogle R.C. Dura mater maintains rat cranial sutures invitro by regulating suture cell proliferation and collagen production. J Craniofac Genet Dev Biol Jul-Sep 1998, 18:150-158.
    • (1998) J Craniofac Genet Dev Biol , vol.18 , pp. 150-158
    • Opperman, L.A.1    Chhabra, A.2    Nolen, A.A.3    Bao, Y.4    Ogle, R.C.5
  • 133
    • 0031797922 scopus 로고    scopus 로고
    • Immunolocalization of basic fibroblast growth factor and fibroblast growth factor receptor-1 and receptor-2 in rat cranial sutures
    • discussion 1818-1820
    • Mehrara B.J., Mackool R.J., McCarthy J.G., Gittes G.K., Longaker M.T. Immunolocalization of basic fibroblast growth factor and fibroblast growth factor receptor-1 and receptor-2 in rat cranial sutures. Plast Reconstr Surg Nov 1998, 102:1805-1817. discussion 1818-1820.
    • (1998) Plast Reconstr Surg , vol.102 , pp. 1805-1817
    • Mehrara, B.J.1    Mackool, R.J.2    McCarthy, J.G.3    Gittes, G.K.4    Longaker, M.T.5
  • 134
    • 0034778449 scopus 로고    scopus 로고
    • Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors
    • Chikazu D., Katagiri M., Ogasawara T., et al. Regulation of osteoclast differentiation by fibroblast growth factor 2: stimulation of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor expression in osteoblasts and inhibition of macrophage colony-stimulating factor function in osteoclast precursors. J Bone Miner Res Nov 2001, 16:2074-2081.
    • (2001) J Bone Miner Res , vol.16 , pp. 2074-2081
    • Chikazu, D.1    Katagiri, M.2    Ogasawara, T.3
  • 135
    • 0028850292 scopus 로고
    • Cranial sutures require tissue interactions with dura mater to resist osseous obliteration invitro
    • Opperman L.A., Passarelli R.W., Morgan E.P., Reintjes M., Ogle R.C. Cranial sutures require tissue interactions with dura mater to resist osseous obliteration invitro. J Bone Miner Res Dec 1995, 10:1978-1987.
    • (1995) J Bone Miner Res , vol.10 , pp. 1978-1987
    • Opperman, L.A.1    Passarelli, R.W.2    Morgan, E.P.3    Reintjes, M.4    Ogle, R.C.5
  • 136
    • 0037861955 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia - genetic short limbed dwarfism
    • Aviezer D., Golembo M., Yayon A. Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia - genetic short limbed dwarfism. Curr Drug Targets Jul 2003, 4:353-365.
    • (2003) Curr Drug Targets , vol.4 , pp. 353-365
    • Aviezer, D.1    Golembo, M.2    Yayon, A.3
  • 137
    • 0027964261 scopus 로고
    • Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
    • Shiang R., Thompson L.M., Zhu Y.Z., et al. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell Jul 29 1994, 78:335-342.
    • (1994) Cell , vol.78 , pp. 335-342
    • Shiang, R.1    Thompson, L.M.2    Zhu, Y.Z.3
  • 138
    • 0028890851 scopus 로고
    • Achondroplasia is defined by recurrent G380R mutations of FGFR3
    • Bellus G.A., Hefferon T.W., Ortiz de Luna R.I., et al. Achondroplasia is defined by recurrent G380R mutations of FGFR3. Am J Hum Genet Feb 1995, 56:368-373.
    • (1995) Am J Hum Genet , vol.56 , pp. 368-373
    • Bellus, G.A.1    Hefferon, T.W.2    Ortiz de Luna, R.I.3
  • 139
    • 33751330697 scopus 로고    scopus 로고
    • Novel FGFR3 mutations creating cysteine residues in the extracellular domain of the receptor cause achondroplasia or severe forms of hypochondroplasia
    • Heuertz S., Le Merrer M., Zabel B., et al. Novel FGFR3 mutations creating cysteine residues in the extracellular domain of the receptor cause achondroplasia or severe forms of hypochondroplasia. Eur J Hum Genet Dec 2006, 14:1240-1247.
    • (2006) Eur J Hum Genet , vol.14 , pp. 1240-1247
    • Heuertz, S.1    Le Merrer, M.2    Zabel, B.3
  • 140
    • 0029912958 scopus 로고    scopus 로고
    • Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism
    • Bonaventure J., Rousseau F., Legeai-Mallet L., Le Merrer M., Munnich A., Maroteaux P. Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism. Am J Med Genet May 3 1996, 63:148-154.
    • (1996) Am J Med Genet , vol.63 , pp. 148-154
    • Bonaventure, J.1    Rousseau, F.2    Legeai-Mallet, L.3    Le Merrer, M.4    Munnich, A.5    Maroteaux, P.6
  • 141
    • 0032253399 scopus 로고    scopus 로고
    • Achondroplasia, hypochondroplasia and thanatophoric dysplasia: clinically related skeletal dysplasias that are also related at the molecular level
    • Cohen M.M. Achondroplasia, hypochondroplasia and thanatophoric dysplasia: clinically related skeletal dysplasias that are also related at the molecular level. Int J Oral Maxillofac Surg Dec 1998, 27:451-455.
    • (1998) Int J Oral Maxillofac Surg , vol.27 , pp. 451-455
    • Cohen, M.M.1
  • 142
    • 0029032394 scopus 로고
    • A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia
    • Bellus G.A., McIntosh I., Smith E.A., et al. A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia. Nat Genet Jul 1995, 10:357-359.
    • (1995) Nat Genet , vol.10 , pp. 357-359
    • Bellus, G.A.1    McIntosh, I.2    Smith, E.A.3
  • 143
    • 79951805648 scopus 로고    scopus 로고
    • A case of thanatophoric dysplasia type I with an R248C mutation in the FGFR3 gene
    • Noe E.J., Yoo H.W., Kim K.N., Lee S.Y. A case of thanatophoric dysplasia type I with an R248C mutation in the FGFR3 gene. Korean J Pediatr Dec 2010, 53:1022-1025.
    • (2010) Korean J Pediatr , vol.53 , pp. 1022-1025
    • Noe, E.J.1    Yoo, H.W.2    Kim, K.N.3    Lee, S.Y.4
  • 144
    • 84890019316 scopus 로고    scopus 로고
    • Emergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumours
    • Parker B.C., Engels M., Annala M., Zhang W. Emergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumours. J Pathol Jan 2014, 232:4-15.
    • (2014) J Pathol , vol.232 , pp. 4-15
    • Parker, B.C.1    Engels, M.2    Annala, M.3    Zhang, W.4
  • 145
    • 79251526177 scopus 로고    scopus 로고
    • Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer
    • Dodurga Y., Tataroglu C., Kesen Z., Satiroglu-Tufan N.L. Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer. Genet Mol Res 2011, 10:86-95.
    • (2011) Genet Mol Res , vol.10 , pp. 86-95
    • Dodurga, Y.1    Tataroglu, C.2    Kesen, Z.3    Satiroglu-Tufan, N.L.4
  • 146
    • 34250829395 scopus 로고    scopus 로고
    • Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
    • Pollock P.M., Gartside M.G., Dejeza L.C., et al. Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Oncogene Nov 1 2007, 26:7158-7162.
    • (2007) Oncogene , vol.26 , pp. 7158-7162
    • Pollock, P.M.1    Gartside, M.G.2    Dejeza, L.C.3
  • 147
    • 33644973673 scopus 로고    scopus 로고
    • FGF signaling in skeletal development
    • Naski M.C., Ornitz D.M. FGF signaling in skeletal development. Front Biosci 1998, 3:d781-794.
    • (1998) Front Biosci , vol.3 , pp. d781-794
    • Naski, M.C.1    Ornitz, D.M.2
  • 148
    • 0030821282 scopus 로고    scopus 로고
    • A role for FGF-6 in skeletal muscle regeneration
    • Floss T., Arnold H.H., Braun T. A role for FGF-6 in skeletal muscle regeneration. Genes Dev Aug 15 1997, 11:2040-2051.
    • (1997) Genes Dev , vol.11 , pp. 2040-2051
    • Floss, T.1    Arnold, H.H.2    Braun, T.3
  • 151
    • 84870858575 scopus 로고    scopus 로고
    • Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia
    • Lorget F., Kaci N., Peng J., et al. Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia. Am J Hum Genet Dec 7 2012, 91:1108-1114.
    • (2012) Am J Hum Genet , vol.91 , pp. 1108-1114
    • Lorget, F.1    Kaci, N.2    Peng, J.3
  • 154
    • 0029937714 scopus 로고    scopus 로고
    • Missense FGFR3 mutations create cysteine residues in thanatophoric dwarfism type I (TD1)
    • Rousseau F., el Ghouzzi V., Delezoide A.L., et al. Missense FGFR3 mutations create cysteine residues in thanatophoric dwarfism type I (TD1). Hum Mol Genet Apr 1996, 5:509-512.
    • (1996) Hum Mol Genet , vol.5 , pp. 509-512
    • Rousseau, F.1    el Ghouzzi, V.2    Delezoide, A.L.3
  • 155
    • 0028860562 scopus 로고
    • Another mutation that results in the substitution of an unpaired cysteine residue in the extracellular domain of FGFR3 in thanatophoric dysplasia type I
    • Tavormina P.L., Rimoin D.L., Cohn D.H., Zhu Y.Z., Shiang R., Wasmuth J.J. Another mutation that results in the substitution of an unpaired cysteine residue in the extracellular domain of FGFR3 in thanatophoric dysplasia type I. Hum Mol Genet Nov 1995, 4:2175-2177.
    • (1995) Hum Mol Genet , vol.4 , pp. 2175-2177
    • Tavormina, P.L.1    Rimoin, D.L.2    Cohn, D.H.3    Zhu, Y.Z.4    Shiang, R.5    Wasmuth, J.J.6
  • 156
    • 84874595852 scopus 로고    scopus 로고
    • Craniosynostosis: molecular pathways and future pharmacologic therapy
    • Senarath-Yapa K., Chung M.T., McArdle A., et al. Craniosynostosis: molecular pathways and future pharmacologic therapy. Organogenesis Oct-Dec 2012, 8:103-113.
    • (2012) Organogenesis , vol.8 , pp. 103-113
    • Senarath-Yapa, K.1    Chung, M.T.2    McArdle, A.3
  • 157
    • 80051863260 scopus 로고    scopus 로고
    • Evaluation and management of nonsyndromic craniosynostosis
    • Ursitti F., Fadda T., Papetti L., et al. Evaluation and management of nonsyndromic craniosynostosis. Acta Paediatr Sep 2011, 100:1185-1194.
    • (2011) Acta Paediatr , vol.100 , pp. 1185-1194
    • Ursitti, F.1    Fadda, T.2    Papetti, L.3
  • 158
    • 45849091135 scopus 로고    scopus 로고
    • Craniofacial sutures. Development, disease and treatment. Preface
    • Rice D.P. Craniofacial sutures. Development, disease and treatment. Preface. Front Oral Bio. 2008, 12:xi.
    • (2008) Front Oral Bio. , vol.12 , pp. xi
    • Rice, D.P.1
  • 159
    • 0024259069 scopus 로고
    • Craniosynostosis update 1987
    • Cohen M.M. Craniosynostosis update 1987. Am J Med Genet Suppl 1988, 4:99-148.
    • (1988) Am J Med Genet Suppl , vol.4 , pp. 99-148
    • Cohen, M.M.1
  • 160
    • 0031683688 scopus 로고    scopus 로고
    • Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand
    • Anderson J., Burns H.D., Enriquez-Harris P., Wilkie A.O., Heath J.K. Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand. Hum Mol Genet Sep 1998, 7:1475-1483.
    • (1998) Hum Mol Genet , vol.7 , pp. 1475-1483
    • Anderson, J.1    Burns, H.D.2    Enriquez-Harris, P.3    Wilkie, A.O.4    Heath, J.K.5
  • 162
    • 0142043966 scopus 로고    scopus 로고
    • The appearance of the feet in Pfeiffer syndrome caused by FGFR1 P252R mutation
    • Rossi M., Jones R.L., Norbury G., Bloch-Zupan A., Winter R.M. The appearance of the feet in Pfeiffer syndrome caused by FGFR1 P252R mutation. Clin Dysmorphol Oct 2003, 12:269-274.
    • (2003) Clin Dysmorphol , vol.12 , pp. 269-274
    • Rossi, M.1    Jones, R.L.2    Norbury, G.3    Bloch-Zupan, A.4    Winter, R.M.5
  • 163
    • 0032992570 scopus 로고    scopus 로고
    • Analysis of the mutational spectrum of the FGFR2 gene in Pfeiffer syndrome
    • Cornejo-Roldan L.R., Roessler E., Muenke M. Analysis of the mutational spectrum of the FGFR2 gene in Pfeiffer syndrome. Hum Genet May 1999, 104:425-431.
    • (1999) Hum Genet , vol.104 , pp. 425-431
    • Cornejo-Roldan, L.R.1    Roessler, E.2    Muenke, M.3
  • 164
    • 84864027660 scopus 로고    scopus 로고
    • Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome
    • Holmes G., Basilico C. Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome. Dev Biol Aug 15 2012, 368:283-293.
    • (2012) Dev Biol , vol.368 , pp. 283-293
    • Holmes, G.1    Basilico, C.2
  • 165
    • 84875957383 scopus 로고    scopus 로고
    • Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome
    • Yeh E., Fanganiello R.D., Sunaga D.Y., et al. Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome. PLoS One 2013, 8:e60439.
    • (2013) PLoS One , vol.8 , pp. e60439
    • Yeh, E.1    Fanganiello, R.D.2    Sunaga, D.Y.3
  • 168
    • 78549260100 scopus 로고    scopus 로고
    • Intestinal malrotation in a patient with Pfeiffer syndrome type 2
    • Zarate Y.A., Putnam P.E., Saal H.M. Intestinal malrotation in a patient with Pfeiffer syndrome type 2. Cleft Palate Craniofac J Nov 2010, 47:638-641.
    • (2010) Cleft Palate Craniofac J , vol.47 , pp. 638-641
    • Zarate, Y.A.1    Putnam, P.E.2    Saal, H.M.3
  • 170
    • 0029109137 scopus 로고
    • Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes
    • Rutland P., Pulleyn L.J., Reardon W., et al. Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. Nat Genet Feb 1995, 9:173-176.
    • (1995) Nat Genet , vol.9 , pp. 173-176
    • Rutland, P.1    Pulleyn, L.J.2    Reardon, W.3
  • 171
    • 12844282848 scopus 로고    scopus 로고
    • A novel insertion in the FGFR2 gene in a patient with Crouzon phenotype and sacrococcygeal tail
    • Lapunzina P., Fernandez A., Sanchez Romero J.M., et al. A novel insertion in the FGFR2 gene in a patient with Crouzon phenotype and sacrococcygeal tail. Birth Defects Res A Clin Mol Teratol Jan 2005, 73:61-64.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 61-64
    • Lapunzina, P.1    Fernandez, A.2    Sanchez Romero, J.M.3
  • 172
    • 0030723994 scopus 로고    scopus 로고
    • Metacarpophalangeal analysis in Crouzon syndrome: additional evidence for phenotypic convergence with the acrocephalosyndactyly syndromes
    • Murdoch-Kinch C.A., Ward R.E. Metacarpophalangeal analysis in Crouzon syndrome: additional evidence for phenotypic convergence with the acrocephalosyndactyly syndromes. Am J Med Genet Nov 28 1997, 73:61-66.
    • (1997) Am J Med Genet , vol.73 , pp. 61-66
    • Murdoch-Kinch, C.A.1    Ward, R.E.2
  • 173
    • 17244379023 scopus 로고    scopus 로고
    • Roles of FGF signaling in skeletal development and human genetic diseases
    • Chen L., Deng C.X. Roles of FGF signaling in skeletal development and human genetic diseases. Front Biosci 2005, 10:1961-1976.
    • (2005) Front Biosci , vol.10 , pp. 1961-1976
    • Chen, L.1    Deng, C.X.2
  • 174
    • 0035399970 scopus 로고    scopus 로고
    • Premature calvarial synostosis and epidermal hyperplasia (Beare-Stevenson syndrome-like anomalies) resulting from a P250R missense mutation in the gene encoding fibroblast growth factor receptor 3
    • Roscioli T., Flanagan S., Mortimore R.J., et al. Premature calvarial synostosis and epidermal hyperplasia (Beare-Stevenson syndrome-like anomalies) resulting from a P250R missense mutation in the gene encoding fibroblast growth factor receptor 3. Am J Med Genet Jul 1 2001, 101:187-194.
    • (2001) Am J Med Genet , vol.101 , pp. 187-194
    • Roscioli, T.1    Flanagan, S.2    Mortimore, R.J.3
  • 175
    • 84867196267 scopus 로고    scopus 로고
    • The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice
    • Percival C.J., Wang Y., Zhou X., Jabs E.W., Richtsmeier J.T. The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice. J Anat Nov 2012, 221:434-442.
    • (2012) J Anat , vol.221 , pp. 434-442
    • Percival, C.J.1    Wang, Y.2    Zhou, X.3    Jabs, E.W.4    Richtsmeier, J.T.5
  • 176
    • 0031468344 scopus 로고    scopus 로고
    • Jackson-Weiss syndrome: identification of two novel FGFR2 missense mutations shared with Crouzon and Pfeiffer craniosynostotic disorders
    • Tartaglia M., Di Rocco C., Lajeunie E., Valeri S., Velardi F., Battaglia P.A. Jackson-Weiss syndrome: identification of two novel FGFR2 missense mutations shared with Crouzon and Pfeiffer craniosynostotic disorders. Hum Genet Nov 1997, 101:47-50.
    • (1997) Hum Genet , vol.101 , pp. 47-50
    • Tartaglia, M.1    Di Rocco, C.2    Lajeunie, E.3    Valeri, S.4    Velardi, F.5    Battaglia, P.A.6
  • 180
    • 0035043261 scopus 로고    scopus 로고
    • Toward an understanding of nonsyndromic craniosynostosis: altered patterns of TGF-beta receptor and FGF receptor expression induced by intrauterine head constraint
    • discussion 553-544
    • Hunenko O., Karmacharya J., Ong G., Kirschner R.E. Toward an understanding of nonsyndromic craniosynostosis: altered patterns of TGF-beta receptor and FGF receptor expression induced by intrauterine head constraint. Ann Plast Surg May 2001, 46:546-553. discussion 553-544.
    • (2001) Ann Plast Surg , vol.46 , pp. 546-553
    • Hunenko, O.1    Karmacharya, J.2    Ong, G.3    Kirschner, R.E.4
  • 181
    • 54749158107 scopus 로고    scopus 로고
    • Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells
    • Meyer A.N., McAndrew C.W., Donoghue D.J. Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells. Cancer Res Sep 15 2008, 68:7362-7370.
    • (2008) Cancer Res , vol.68 , pp. 7362-7370
    • Meyer, A.N.1    McAndrew, C.W.2    Donoghue, D.J.3
  • 182
    • 2342566403 scopus 로고    scopus 로고
    • Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074
    • Grand E.K., Chase A.J., Heath C., Rahemtulla A., Cross N.C. Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Leukemia May 2004, 18:962-966.
    • (2004) Leukemia , vol.18 , pp. 962-966
    • Grand, E.K.1    Chase, A.J.2    Heath, C.3    Rahemtulla, A.4    Cross, N.C.5
  • 183
    • 52049086201 scopus 로고    scopus 로고
    • Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
    • Byron S.A., Gartside M.G., Wellens C.L., et al. Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation. Cancer Res Sep 1 2008, 68:6902-6907.
    • (2008) Cancer Res , vol.68 , pp. 6902-6907
    • Byron, S.A.1    Gartside, M.G.2    Wellens, C.L.3
  • 184
    • 33947504730 scopus 로고    scopus 로고
    • Sunitinib: from rational design to clinical efficacy
    • Chow L.Q., Eckhardt S.G. Sunitinib: from rational design to clinical efficacy. J Clin Oncol Mar 1 2007, 25:884-896.
    • (2007) J Clin Oncol , vol.25 , pp. 884-896
    • Chow, L.Q.1    Eckhardt, S.G.2
  • 185
    • 47949114797 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders
    • Cross N.C., Reiter A. Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders. Acta Haematol 2008, 119:199-206.
    • (2008) Acta Haematol , vol.119 , pp. 199-206
    • Cross, N.C.1    Reiter, A.2
  • 186
    • 1642421743 scopus 로고    scopus 로고
    • Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations
    • Roumiantsev S., Krause D.S., Neumann C.A., et al. Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations. Cancer Cell Mar 2004, 5:287-298.
    • (2004) Cancer Cell , vol.5 , pp. 287-298
    • Roumiantsev, S.1    Krause, D.S.2    Neumann, C.A.3
  • 187
    • 0036205735 scopus 로고    scopus 로고
    • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
    • Ohbayashi N., Shibayama M., Kurotaki Y., et al. FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev Apr 1 2002, 16:870-879.
    • (2002) Genes Dev , vol.16 , pp. 870-879
    • Ohbayashi, N.1    Shibayama, M.2    Kurotaki, Y.3
  • 188
    • 0036203355 scopus 로고    scopus 로고
    • Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
    • Liu Z., Xu J., Colvin J.S., Ornitz D.M. Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev Apr 1 2002, 16:859-869.
    • (2002) Genes Dev , vol.16 , pp. 859-869
    • Liu, Z.1    Xu, J.2    Colvin, J.S.3    Ornitz, D.M.4
  • 189
    • 0036246477 scopus 로고    scopus 로고
    • Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors
    • Ellsworth J.L., Berry J., Bukowski T., et al. Fibroblast growth factor-18 is a trophic factor for mature chondrocytes and their progenitors. Osteoarthr Cartilage Apr 2002, 10:308-320.
    • (2002) Osteoarthr Cartilage , vol.10 , pp. 308-320
    • Ellsworth, J.L.1    Berry, J.2    Bukowski, T.3
  • 190
    • 20944443514 scopus 로고    scopus 로고
    • Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis
    • Moore E.E., Bendele A.M., Thompson D.L., et al. Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis. Osteoarthr Cartilage Jul 2005, 13:623-631.
    • (2005) Osteoarthr Cartilage , vol.13 , pp. 623-631
    • Moore, E.E.1    Bendele, A.M.2    Thompson, D.L.3
  • 191
    • 5444230191 scopus 로고    scopus 로고
    • Spinal cord repair with acidic fibroblast growth factor as a treatment for a patient with chronic paraplegia
    • Cheng H., Liao K.K., Liao S.F., Chuang T.Y., Shih Y.H. Spinal cord repair with acidic fibroblast growth factor as a treatment for a patient with chronic paraplegia. Spine (Phila Pa 1976) Jul 15 2004, 29:E284-E288.
    • (2004) Spine (Phila Pa 1976) , vol.29 , pp. E284-E288
    • Cheng, H.1    Liao, K.K.2    Liao, S.F.3    Chuang, T.Y.4    Shih, Y.H.5
  • 192
    • 0032562232 scopus 로고    scopus 로고
    • Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease
    • Schumacher B., Pecher P., von Specht B.U., Stegmann T. Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease. Circulation Feb 24 1998, 97:645-650.
    • (1998) Circulation , vol.97 , pp. 645-650
    • Schumacher, B.1    Pecher, P.2    von Specht, B.U.3    Stegmann, T.4
  • 193
    • 0036658287 scopus 로고    scopus 로고
    • Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein
    • Ruel M., Laham R.J., Parker J.A., et al. Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein. J Thorac Cardiovasc Surg Jul 2002, 124:28-34.
    • (2002) J Thorac Cardiovasc Surg , vol.124 , pp. 28-34
    • Ruel, M.1    Laham, R.J.2    Parker, J.A.3
  • 194
    • 34548446034 scopus 로고    scopus 로고
    • Effects of Ad5FGF-4 in patients with angina: an analysis of pooled data from the AGENT-3 and AGENT-4 trials
    • Henry T.D., Grines C.L., Watkins M.W., et al. Effects of Ad5FGF-4 in patients with angina: an analysis of pooled data from the AGENT-3 and AGENT-4 trials. J Am Coll Cardiol Sep 11 2007, 50:1038-1046.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1038-1046
    • Henry, T.D.1    Grines, C.L.2    Watkins, M.W.3
  • 195
    • 47849084832 scopus 로고    scopus 로고
    • Antidepressant-like effects of intracerebroventricular FGF2 in rats
    • Turner C.A., Gula E.L., Taylor L.P., Watson S.J., Akil H. Antidepressant-like effects of intracerebroventricular FGF2 in rats. Brain Res Aug 11 2008, 1224:63-68.
    • (2008) Brain Res , vol.1224 , pp. 63-68
    • Turner, C.A.1    Gula, E.L.2    Taylor, L.P.3    Watson, S.J.4    Akil, H.5
  • 196
    • 0344109562 scopus 로고    scopus 로고
    • Keratinocyte growth factor: a unique player in epithelial repair processes
    • Werner S. Keratinocyte growth factor: a unique player in epithelial repair processes. Cytokine Growth Factor Rev Jun 1998, 9:153-165.
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 153-165
    • Werner, S.1
  • 197
    • 2542505481 scopus 로고    scopus 로고
    • Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
    • Fu L., John L.M., Adams S.H., et al. Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology Jun 2004, 145:2594-2603.
    • (2004) Endocrinology , vol.145 , pp. 2594-2603
    • Fu, L.1    John, L.M.2    Adams, S.H.3
  • 199
    • 85047689727 scopus 로고    scopus 로고
    • Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model
    • Takagi Y., Takahashi J., Saiki H., et al. Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest Jan 2005, 115:102-109.
    • (2005) J Clin Invest , vol.115 , pp. 102-109
    • Takagi, Y.1    Takahashi, J.2    Saiki, H.3
  • 200
    • 0027931643 scopus 로고
    • FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations
    • Hebert J.M., Rosenquist T., Gotz J., Martin G.R. FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell Sep 23 1994, 78:1017-1025.
    • (1994) Cell , vol.78 , pp. 1017-1025
    • Hebert, J.M.1    Rosenquist, T.2    Gotz, J.3    Martin, G.R.4
  • 201
    • 80855165240 scopus 로고    scopus 로고
    • Roles of FGF signaling in stem cell self-renewal, senescence and aging
    • Coutu D.L., Galipeau J. Roles of FGF signaling in stem cell self-renewal, senescence and aging. Aging (Albany NY) Oct 2011, 3:920-933.
    • (2011) Aging (Albany NY) , vol.3 , pp. 920-933
    • Coutu, D.L.1    Galipeau, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.