Differences in left-right axis pathways in house and chick: Functions of FGF8 and SHH

Science

Volumn 285, Issue 5426, 1999, Pages 403-406

  Meyers, Erik N ^a,b   Martin, Gail R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; EMBRYO AXIS; EMBRYO DEVELOPMENT; GENE EXPRESSION; HETEROZYGOTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; BODY PATTERNING; CHICK EMBRYO; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; EMBRYONIC INDUCTION; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART DEFECTS, CONGENITAL; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; LUNG; MESODERM; MICE; MUTATION; NUCLEAR PROTEINS; PAIRED BOX TRANSCRIPTION FACTORS; PROTEINS; RECOMBINANT PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; ERINACEIDAE; MAMMALIA; VERTEBRATA;

EID: 0033575364     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5426.403     Document Type: Article

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37. -/+ mice, respectively. We thank M. Kuehn, H. Hamada, and M. Blum for Nodal, Lefty, and Pitx2 probes, respectively, and J. Bristow and D. Goldman for helpful advice. We thank M. Embry and A. Gannon for technical assistance. We are also grateful to S. Strickland and our laboratory colleagues for critical readings of the manuscript. E.N.M. was supported by a Mentored Clinical Scientist Development award HD01216 from the NIH. This work was supported by NIH grant RO1 HD34380 (G.R.M.).