Vertebrate limb development - The early stages in chick and mouse

Current Opinion in Genetics and Development

Volumn 11, Issue 4, 2001, Pages 476-481

  Tickle, Cheryll ^a   Münsterberg, Andrea ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR;

CHICK EMBRYO; ECTODERM; EMBRYO DEVELOPMENT; GENE EXPRESSION; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; VERTEBRATE;

EID: 0035427231     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00220-3     Document Type: Review

References (37)

1. Fibroblast growth factors induce additional lib development from the flank of the chick embryos
2. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless
3. Fgf10 is essential for limb and lung formation
4. FGF4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
5. Wnt signals control FGF-dependent limb initiation and AER induction in the chick embryo
6. The mesenchymal factor, Fgf10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
7. FGF and genes encoding transcription factors in early limb specification
8. -/-) mice
9. CSAL1 is controlled by a combination of FGF and Wnt signals in developing limb buds
10. Identification of synergistic signals initiating inner ear development
11. The status of Wnt signalling regulates neural and epidermal fates in the chick embryo
12. Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1 or Bmp4
13. FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development
14. Fgf8 signalling from the AER is essential for normal limb development
15. Fgf8 is required for outgrowth and patterning of the limbs
16. Normal limb development in conditional mutants of Fgf4
17. Conditional inactivation of Fgf4 reveals complexity of signaling during limb bud development
18. Positional information in chick limb morphogenesis
19. The effect of cell killing by x-irradiation on pattern formation in the chick limb
20. The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure
21. Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb
22. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation
23. Distribution of polarizing activity and potential for limb formation in mouse and chick embryos and possible relationships to polydactyly
24. Expression of radical fringe in limbbud ectoderm regulates apical ectodermal ridge formation
25. Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb
26. Glycosyltransferase activity of fringe modulates notch-delta interactions
27. The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD
28. Fringe is a glycosyltransferase that modifies notch
29. A chick homologue of serrate and its relationship with notch and delta homologues during central neurogenesis
30. Engrailed-1 misexpression in chick embryos prevents apical ridge formation but preserves segregation of dorsal and ventral ectodermal compartments
31. The mouse Engrailed-1 gene and ventral limb patterning
32. The role of Engrailed in establishing the dorso-ventral axis in chick limb
33. Evidence that members of the Cut/Cux/CDP family may be involved in AER positioning and polarizing activity during chick limb development
34. Apical ectodermal ridge induction by the transplantation of En-1-over-expressing ectoderm in the chick limb bud
35. The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity
36. Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds
37. Role of Pitx1 upstream of Tbx4 in specification of hindlimb identity