Novel Molecular Pathways Elicited by Mutant FGFR2 May Account for Brain Abnormalities in Apert Syndrome

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Yeh, Erika ^a   Fanganiello, Roberto D ^a   Sunaga, Daniele Y ^a   Zhou, Xueyan ^b   Holmes, Gregory ^b   Rocha, Katia M ^a   Alonso, Nivaldo ^a   Matushita, Hamilton ^a   Wang, Yingli ^b   Jabs, Ethylin W ^b   Passos Bueno, Maria Rita ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2;

ACROCEPHALOSYNDACTYLY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN MALFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; CROUZON SYNDROME; ENDOTHELIUM CELL; FGFR2 GENE; FIBROBLAST; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; MUTANT; NEWBORN; NONHUMAN; PERIOSTEUM; SIGNAL TRANSDUCTION; WILD TYPE;

ACROCEPHALOSYNDACTYLIA; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; PROTEINS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION;

EID: 84875957383     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060439     Document Type: Article

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