The docking protein FRS2α controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

Molecular Cell

Volumn 10, Issue 4, 2002, Pages 709-719

  Lax, Irit ^a   Wong, Andy ^a   Lamothe, Betty ^a   Lee, Arnold ^a   Frost, Adam ^a   Hawes, Jessica ^a   Schlessinger, Joseph ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN; PROTEIN FRS2ALPHA; THREONINE; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; FRS2 PROTEIN, HUMAN; GRB2 PROTEIN, HUMAN; GRB2 PROTEIN, MOUSE; GRB2 PROTEIN, RAT; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHOPROTEIN; PHOSPHOTHREONINE; PHOSPHOTYROSINE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; BINDING SITE; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; CELL ADHESION; CELL DIVISION; CELL LINE; CELL MOTION; CELL STRAIN; DRUG EFFECT; FEEDBACK SYSTEM; GEL MOBILITY SHIFT ASSAY; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; RAT;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL ADHESION; CELL DIVISION; CELL LINE; CELL MOVEMENT; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEEDBACK, BIOCHEMICAL; FIBROBLAST GROWTH FACTORS; GRB2 ADAPTOR PROTEIN; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTATION; PC12 CELLS; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTHREONINE; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEINS; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR;

EID: 0036771763     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00689-5     Document Type: Article

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