Sfrp5 mediates glucose-induced proliferation in rat pancreatic β-cells

Journal of Endocrinology

Volumn 229, Issue 2, 2016, Pages 73-83

  Guan, Binbin ^a,b   Li, Wenyi ^a   Li, Fengying ^a   Xie, Yun ^a   Ni, Qicheng ^a   Gu, Yanyun ^a   Li, Xiaoying ^a   Wang, Qidi ^a   Zhang, Hongli ^a   Ning, Guang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Fujian Union Hospital   (China)

Author keywords

Glucose; Proliferation; Sfrp5; cell

Indexed keywords

CYCLIN D2; GLUCOSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SECRETED FRIZZLED RELATED PROTEIN 5; ADIPOCYTOKINE; CCND2 PROTEIN, RAT; SECRETED FRIZZLED-RELATED PROTEIN 5, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; IMMUNOFLUORESCENCE; INS 1 CELL LINE; LUCIFERASE ASSAY; MALE; MOLECULAR BIOLOGY; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANIMAL; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT; UPREGULATION;

ADIPOKINES; ANIMALS; CELL LINE; CELL PROLIFERATION; CYCLIN D2; GENE EXPRESSION; GLUCOSE; INSULIN-SECRETING CELLS; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UP-REGULATION; WNT SIGNALING PATHWAY;

EID: 84977675575     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-15-0535     Document Type: Article

References (42)

1. Accili D 2001 A kinase in the life of the beta cell. Journal of Clinical Investigation 108 1575-1576. (doi:10.1172/JCI14454)
2. Alonso LC, Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP & Garcia-Ocana A 2007 Glucose infusion in mice: a new model to induce beta-cell replication. Diabetes 56 1792-1801. (doi:10.2337/db06-1513)
3. Assmann A, Ueki K, Winnay JN, Kadowaki T & Kulkarni RN 2009 Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2. Molecular and Cellular Biology 29 3219-3228. (doi:10.1128/MCB.01489-08)
4. Bonner-Weir S 2000 Islet growth and development in the adult. Journal of Molecular Endocrinology 24 297-302. (doi:10.1677/jme.0.0240297)
5. Bonner-Weir S, Deery D, Leahy JL & Weir GC 1989 Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 38 49-53. (doi:10.2337/diab.38.1.49)
6. Brelje TC, Scharp DW, Lacy PE, Ogren L, Talamantes F, Robertson M, Friesen HG & Sorenson RL 1993 Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy. Endocrinology 132 879-887. (doi:10.1210/endo.132.2.8425500)
7. Buckbinder L, Talbott R, Velasco-Miguel S, Takenaka I, Faha B, Seizinger BR & Kley N 1995 Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 377 646-649. (doi:10.1038/377646a0)
8. Buteau J, Foisy S, Joly E & Prentki M 2003 Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor. Diabetes 52 124-132. (doi:10.2337/diabetes.52.1.124)
9. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA & Butler PC 2003 Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52 102-110. (doi:10.2337/diabetes.52.1.102)
10. Chen S, Shimoda M, Chen J, Matsumoto S & Grayburn PA 2012 Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration. Cell Cycle 11 695-705. (doi:10.4161/cc.19928)
11. Chick WL 1973 Beta cell replication in rat pancreatic monolayer cultures. Effects of glucose, tolbutamide, glucocorticoid, growth hormone and glucagon. Diabetes 22 687-693. (doi:10.2337/diab.22.9.687)
12. Chocarro-Calvo A, Garcia-Martinez JM, Ardila-Gonzalez S, De la Vieja A & Garcia-Jimenez C 2013 Glucose-induced beta-catenin acetylation enhances Wnt signaling in cancer. Molecular Cell 49 474-486. (doi:10.1016/j.molcel.2012.11.022)
13. Cozar-Castellano I, Weinstock M, Haught M, Velazquez-Garcia S, Sipula D & Stewart AF 2006 Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip. Diabetes 55 70-77. (doi:10.2337/diabetes.55.01.06.db05-0632)
14. Dor Y, Brown J, Martinez OI & Melton DA 2004 Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429 41-46. (doi:10.1038/nature02520)
15. Figeac F, Uzan B, Faro M, Chelali N, Portha B & Movassat J 2010 Neonatal growth and regeneration of beta-cells are regulated by the Wnt/betacatenin signaling in normal and diabetic rats. American Journal of Physiology: Endocrinology and Metabolism 298 E245-256. (doi:10.1152/ajpendo.00538.2009)
16. Finegood DT, Scaglia L & Bonner-Weir S 1995 Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 44 249-256. (doi:10.2337/diab.44.3.249)
17. Fukumoto S, Hsieh CM, Maemura K, Layne MD, Yet SF, Lee KH, Matsui T, Rosenzweig A, Taylor WG, Rubin JS, et al. 2001 Akt participation in the Wnt signaling pathway through dishevelled. Journal of Biological Chemistry 276 17479-17483. (doi:10.1074/jbc.C000880200)
18. Gupta RK, Gao N, Gorski RK, White P, Hardy OT, Rafiq K, Brestelli JE, Chen G, Stoeckert CJ Jr & Kaestner KH 2007 Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. Genes & Development 21 756-769. (doi:10.1101/gad.1535507)
19. Heit JJ, Karnik SK & Kim SK 2006 Intrinsic regulators of pancreatic betacell proliferation. Annual Review of Cell and Developmental Biology 22 311-338. (doi:10.1146/annurev.cellbio.22.010305.104425)
20. Hugl SR, White MF & Rhodes CJ 1998 Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. Journal of Biological Chemistry 273 17771-17779. (doi:10.1074/jbc.273.28.17771)
21. Hu W, Li L, Yang M, Luo X, Ran W, Liu D, Xiong Z, Liu H & Yang G 2013 Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans. Journal of Clinical Endocrinology & Metabolism 98 290-298. (doi:10.1210/jc.2012-2466)
22. Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M & Montminy M 2003 cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes & Development 17 1575-1580. (doi:10.1101/gad.1097103)
23. Kasuga M 2006 Insulin resistance and pancreatic beta cell failure. Journal of Clinical Investigation 116 1756-1760. (doi:10.1172/JCI29189)
24. Kawano Y & Kypta R 2003 Secreted antagonists of the Wnt signalling pathway. Journal of Cell Science 116 2627-2634. (doi:10.1242/jcs.00623)
25. Kushner JA, Ciemerych MA, Sicinska E, Wartschow LM, Teta M, Long SY, Sicinski P & White MF 2005 Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth. Molecular and Cellular Biology 25 3752-3762. (doi:10.1128/MCB.25.9.3752-3762.2005)
26. Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, et al. 2010 Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. Gastroenterology 139 869-881, 881 e861-869. (doi:10.1053/j.gastro.2010.05.037)
27. Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP, et al. 2011 Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice. Diabetologia 54 572-582. (doi:10.1007/s00125-010-1919-1)
28. Lingohr MK, Briaud I, Dickson LM, McCuaig JF, Alarcon C, Wicksteed BL & Rhodes CJ 2006 Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells. Journal of Biological Chemistry 281 15884-15892. (doi:10.1074/jbc.M600356200)
29. Liu Z & Habener JF 2008 Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. Journal of Biological Chemistry 283 8723-8735. (doi:10.1074/jbc.m706105200)
30. Mao J, Hu X, Xiao Y, Yang C, Ding Y, Hou N, Wang J, Cheng H & Zhang X 2013 Overnutrition stimulates intestinal epithelium proliferation through beta-catenin signaling in obese mice. Diabetes 62 3736-3746. (doi:10.2337/db13-0035)
31. Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM et al. 2012 ChREBP mediates glucose-stimulated pancreatic beta-cell proliferation. Diabetes 61 2004-2015. (doi:10.2337/db11-0802)
32. Mori H, Prestwich TC, Reid MA, Longo KA, Gerin I, Cawthorn WP, Susulic VS, Krishnan V, Greenfield A & Macdougald OA 2012 Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition. Journal of Clinical Investigation 122 2405-2416. (doi:10.1172/JCI63604)
33. Ogino J, Sakurai K, Yoshiwara K, Suzuki Y, Ishizuka N, Seki N, Koseki H, Shirasawa T, Hashimoto N, Yagui K, et al. 2006 Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L). Journal of Endocrinology 190 739-747. (doi:10.1677/joe.1.06849)
34. Okada T, Liew CW, Hu J, Hinault C, Michael MD, Krtzfeldt J, Yin C, Holzenberger M, Stoffel M & Kulkarni RN 2007 Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance. PNAS 104 8977-8982. (doi:10.1073/pnas.0608703104)
35. Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A & Walsh K 2010 Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science 329 454-457. (doi:10.1126/science.1188280)
36. Porat S, Weinberg- N, Tornovsky-Babaey S, Schyr-Ben-Haroush R, Hija A, Stolovich-Rain M, Dadon D, Granot Z, Ben-Hur V, White P, et al. 2011 Control of pancreatic beta cell regeneration by glucose metabolism. Cell Metabolism 13 440-449. (doi:10.1016/j.cmet.2011.02.012)
37. Prentki M & Nolan CJ 2006 Islet beta cell failure in type 2 diabetes. Journal of Clinical Investigation 116 1802-1812. (doi:10.1172/jci29103)
38. Rebuffat SA, Oliveira JM, Altirriba J, Palau N, Garcia A, Esteban Y, Nadal B & Gomis R 2013 Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat. Diabetologia 56 2446-2455. (doi:10.1007/s00125-013-3030-x)
39. Rhodes CJ 2005 Type 2 diabetes-a matter of beta-cell life and death? Science 307 380-384. (doi:10.1126/science.1104345)
40. Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M & Kim SK 2007 Wnt signaling regulates pancreatic beta cell proliferation. PNAS 104 6247-6252. (doi:10.1073/pnas.0701509104)
41. Rulifson IC, Majeti JZ, Xiong Y, Hamburger A, Lee KJ, Miao L, Lu M, Gardner J, Gong Y, Wu H, et al. 2014 Inhibition of secreted frizzled-related protein 5 improves glucose metabolism. American Journal of Physiology: Endocrinology and Metabolism 307 1144-1152. (doi:10.1152/ajpendo.00283.2014)
42. Salpeter SJ, Klochendler A, Weinberg-Corem N, Porat S, Granot Z, Shapiro AM, Magnuson MA, Eden A, Grimsby J, Glaser B, et al. 2011 Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic beta-cells through glycolysis and calcium channels. Endocrinology 152 2589-2598. (doi:10.1210/en.2010-1372)