메뉴 건너뛰기




Volumn 18, Issue 2, 2016, Pages 117-126

MicroRNA-based linkage between aging and cancer: From epigenetics view point

Author keywords

Ageing; Disability; Genomics; Longevity; MicroRNAs

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA;

EID: 84976873337     PISSN: 22285806     EISSN: 22285814     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (75)
  • 1
    • 84891429025 scopus 로고    scopus 로고
    • The good and the bad of being connected: The integrons of aging
    • Dillin A, Gottschling DE, Nyström T. The good and the bad of being connected: the integrons of aging. Curr Opin Cell Biol. 2014; 26: 107-112.
    • (2014) Curr Opin Cell Biol. , vol.26 , pp. 107-112
    • Dillin, A.1    Gottschling, D.E.2    Nyström, T.3
  • 2
    • 84925740462 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment in oncology
    • Mohile SG, Magnuson A. Comprehensive geriatric assessment in oncology. Interdiscip Top Gerontol. 2013; 38: 85-103.
    • (2013) Interdiscip Top Gerontol. , vol.38 , pp. 85-103
    • Mohile, S.G.1    Magnuson, A.2
  • 3
    • 84899106437 scopus 로고    scopus 로고
    • MicroRNA let-7a-3 gene methylation is associated with karyotyping, CEBPA promoter methylation, and survival in acute myeloid leukemia
    • Ko YC, Fang WH, Lin TC, Hou HA, Chen CY, Tien HF, et al. MicroRNA let-7a-3 gene methylation is associated with karyotyping, CEBPA promoter methylation, and survival in acute myeloid leukemia. Leuk Res. 2014; 38(5): 625-631.
    • (2014) Leuk Res. , vol.38 , Issue.5 , pp. 625-631
    • Ko, Y.C.1    Fang, W.H.2    Lin, T.C.3    Hou, H.A.4    Chen, C.Y.5    Tien, H.F.6
  • 6
    • 84869087503 scopus 로고    scopus 로고
    • miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner
    • Chitnis NS, Pytel D, Bobrovnikova-Marjon E, Pant D, Zheng H, Maas NL, et al. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol Cell. 2012; 48(3): 353-364.
    • (2012) Mol Cell. , vol.48 , Issue.3 , pp. 353-364
    • Chitnis, N.S.1    Pytel, D.2    Bobrovnikova-Marjon, E.3    Pant, D.4    Zheng, H.5    Maas, N.L.6
  • 9
    • 84867776385 scopus 로고    scopus 로고
    • MicroRNAs as diagnostic biomarkers in gastric cancer
    • Yin Y, Li J, Chen S, Zhou T, Si J. MicroRNAs as diagnostic biomarkers in gastric cancer. Int J Mol Sci. 2012; 13(10): 12544-12555.
    • (2012) Int J Mol Sci. , vol.13 , Issue.10 , pp. 12544-12555
    • Yin, Y.1    Li, J.2    Chen, S.3    Zhou, T.4    Si, J.5
  • 10
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004; 5(7): 522-531.
    • (2004) Nat Rev Genet. , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 12
    • 43449090367 scopus 로고    scopus 로고
    • MicroRNA-10a binds the 5'Utr of ribosomal protein mRNAs and enhances their translation
    • Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell. 2008; 30(4): 460-471.
    • (2008) Mol Cell. , vol.30 , Issue.4 , pp. 460-471
    • Orom, U.A.1    Nielsen, F.C.2    Lund, A.H.3
  • 13
    • 78650004201 scopus 로고    scopus 로고
    • MicroRNA: Biogenesis, function and role in cancer
    • Macfarlane LA, Murphy PR. MicroRNA: biogenesis, function and role in cancer. Curr Genomics. 2010; 11(7): 537-561.
    • (2010) Curr Genomics. , vol.11 , Issue.7 , pp. 537-561
    • Macfarlane, L.A.1    Murphy, P.R.2
  • 14
    • 33344477448 scopus 로고    scopus 로고
    • Genomics of microRNA
    • Kim VN, Nam JW. Genomics of microRNA. Trends Genet. 2006; 22(3): 165-173.
    • (2006) Trends Genet. , vol.22 , Issue.3 , pp. 165-173
    • Kim, V.N.1    Nam, J.W.2
  • 15
    • 33846927800 scopus 로고    scopus 로고
    • Ribonuclease revisited: Structural insights into ribonuclease III family enzymes
    • MacRae IJ, Doudna JA. Ribonuclease revisited: structural insights into ribonuclease III family enzymes. Curr Opin Struct Biol. 2007; 17(1): 138-145.
    • (2007) Curr Opin Struct Biol. , vol.17 , Issue.1 , pp. 138-145
    • MacRae, I.J.1    Doudna, J.A.2
  • 16
    • 68549128834 scopus 로고    scopus 로고
    • Pirnas mediate posttranscriptional retroelement silencing and localization to pi-bodies in the drosophila germline
    • Lim AK, Tao L, Kai T. piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. J Cell Biol. 2009; 186(3): 333-342.
    • (2009) J Cell Biol. , vol.186 , Issue.3 , pp. 333-342
    • Lim, A.K.1    Tao, L.2    Kai, T.3
  • 17
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • Carthew RW, Sontheimer EJ. Origins and mechanisms of miRNAs and siRNAs. Cell. 2009; 136(4): 642-655.
    • (2009) Cell , vol.136 , Issue.4 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 18
    • 51449085579 scopus 로고    scopus 로고
    • Origins and evolution of Eukaryotic RNA interference
    • Shabalina SA, Koonin EV. Origins and evolution of eukaryotic RNA interference. Trends Ecol EVol. 2008; 23(10): 578-587.
    • (2008) Trends Ecol EVol , vol.23 , Issue.10 , pp. 578-587
    • Shabalina, S.A.1    Koonin, E.V.2
  • 19
    • 15944402920 scopus 로고    scopus 로고
    • Small regulatory RNAs in mammals
    • Mattick JS, Makunin IV. Small regulatory RNAs in mammals. Hum Mol Genet. 2005; 14 Spec No 1: R121-132.
    • (2005) Hum Mol Genet. , vol.14 , Issue.1 , pp. R121-R132
    • Mattick, J.S.1    Makunin, I.V.2
  • 20
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 2006; 20(5): 515-524.
    • (2006) Genes Dev. , vol.20 , Issue.5 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 21
    • 84875122028 scopus 로고    scopus 로고
    • Chemical inhibitors and microRNAs (miRNA) targeting the Mammalian target of rapamycin (Mtor) pathway: Potential for novel anticancer therapeutics
    • Alqurashi N, Hashimi SM, Wei MQ. Chemical inhibitors and microRNAs (miRNA) targeting the mammalian target of rapamycin (mTOR) pathway: potential for novel anticancer therapeutics. Int J Mol Sci. 2013; 14(2): 3874-3900.
    • (2013) Int J Mol Sci. , vol.14 , Issue.2 , pp. 3874-3900
    • Alqurashi, N.1    Hashimi, S.M.2    Wei, M.Q.3
  • 22
    • 84857675728 scopus 로고    scopus 로고
    • The mTOR signalling pathway in human cancer
    • Pópulo H, Lopes JM, Soares P. The mTOR signalling pathway in human cancer. Int J Mol Sci. 2012; 13(2): 1886-1918.
    • (2012) Int J Mol Sci. , vol.13 , Issue.2 , pp. 1886-1918
    • Pópulo, H.1    Lopes, J.M.2    Soares, P.3
  • 23
    • 77953577017 scopus 로고    scopus 로고
    • Mtor's role in ageing: Protein synthesis or autophagy?
    • Hands SL, Proud CG, Wyttenbach A. mTOR's role in ageing: protein synthesis or autophagy? Aging (Albany NY). 2009; 1(7): 586-597.
    • (2009) Aging (Albany NY) , vol.1 , Issue.7 , pp. 586-597
    • Hands, S.L.1    Proud, C.G.2    Wyttenbach, A.3
  • 25
    • 84878403310 scopus 로고    scopus 로고
    • MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing
    • Jin Y, Tymen SD, Chen D, Fang ZJ, Zhao Y, Dragas D, et al. MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing. PLoS One. 2013; 8(5): e64434.
    • (2013) PLoS One , vol.8 , Issue.5
    • Jin, Y.1    Tymen, S.D.2    Chen, D.3    Fang, Z.J.4    Zhao, Y.5    Dragas, D.6
  • 26
    • 79952739991 scopus 로고    scopus 로고
    • MicroRNA-100 regulates neovascularization by suppression of Mammalian target of rapamycin in endothelial and vascular smooth muscle cells
    • Grundmann S, Hans FP, Kinniry S, Heinke J, Helbing T, Bluhm F, et al. MicroRNA-100 regulates neovascularization by suppression of mammalian target of rapamycin in endothelial and vascular smooth muscle cells. Circulation 2011; 123(9): 999-1009.
    • (2011) Circulation , vol.123 , Issue.9 , pp. 999-1009
    • Grundmann, S.1    Hans, F.P.2    Kinniry, S.3    Heinke, J.4    Helbing, T.5    Bluhm, F.6
  • 27
  • 28
    • 84894436700 scopus 로고    scopus 로고
    • Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
    • Wan G, Xie W, Liu Z, Xu W, Lao Y, Huang N, et al. Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway. Autophagy 2014; 10(1): 70-79.
    • (2014) Autophagy , vol.10 , Issue.1 , pp. 70-79
    • Wan, G.1    Xie, W.2    Liu, Z.3    Xu, W.4    Lao, Y.5    Huang, N.6
  • 29
    • 84880367902 scopus 로고    scopus 로고
    • The mTOR pathway negatively controls ATM by up-regulating miRNAs
    • Shen C, Houghton PJ. The mTOR pathway negatively controls ATM by up-regulating miRNAs. Proc Natl Acad Sci USA. 2013; 110(29): 11869-11874.
    • (2013) Proc Natl Acad Sci U.S.A. , vol.110 , Issue.29 , pp. 11869-11874
    • Shen, C.1    Houghton, P.J.2
  • 30
    • 84874812950 scopus 로고    scopus 로고
    • miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma
    • Zhong M, Bian Z, Wu Z. miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma. Cell Physiol Biochem. 2013; 31(23): 209-218.
    • (2013) Cell Physiol Biochem. , vol.31 , Issue.23 , pp. 209-218
    • Zhong, M.1    Bian, Z.2    Wu, Z.3
  • 31
    • 84874432277 scopus 로고    scopus 로고
    • MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells
    • Wang Y, Liu J, Liu C, Naji A, Stoffers DA. MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells. Diabetes. 2013; 62(3): 887-895.
    • (2013) Diabetes , vol.62 , Issue.3 , pp. 887-895
    • Wang, Y.1    Liu, J.2    Liu, C.3    Naji, A.4    Stoffers, D.A.5
  • 32
    • 84870299410 scopus 로고    scopus 로고
    • Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma
    • Li G, Cai M, Fu D, Chen K, Sun M, Cai Z, et al. Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma. Cell Physiol Biochem. 2012; 30(6): 1481-1490.
    • (2012) Cell Physiol Biochem , vol.30 , Issue.6 , pp. 1481-1490
    • Li, G.1    Cai, M.2    Fu, D.3    Chen, K.4    Sun, M.5    Cai, Z.6
  • 33
    • 84869885702 scopus 로고    scopus 로고
    • MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma
    • Cui L, Zhou H, Zhao H, Zhou Y, Xu R, Xu X, et al. MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma. BMC Cancer. 2012; 12: 546.
    • (2012) BMC Cancer , vol.12 , pp. 546
    • Cui, L.1    Zhou, H.2    Zhao, H.3    Zhou, Y.4    Xu, R.5    Xu, X.6
  • 34
    • 84870328663 scopus 로고    scopus 로고
    • Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway
    • Iwaya T, Yokobori T, Nishida N, Kogo R, Sudo T, Tanaka F, et al. Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway. Carcinogenesis. 2012; 33(12): 2391-2397.
    • (2012) Carcinogenesis , vol.33 , Issue.12 , pp. 2391-2397
    • Iwaya, T.1    Yokobori, T.2    Nishida, N.3    Kogo, R.4    Sudo, T.5    Tanaka, F.6
  • 35
    • 84880305345 scopus 로고    scopus 로고
    • miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling
    • Gebeshuber CA, Martinez J. miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. Oncogene. 2013; 32(27): 3306-3310.
    • (2013) Oncogene , vol.32 , Issue.27 , pp. 3306-3310
    • Gebeshuber, C.A.1    Martinez, J.2
  • 36
    • 84902344416 scopus 로고    scopus 로고
    • MiR506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer
    • Liu G, Sun Y, Ji P, Li X, Cogdell D, Yang D, et al. MiR506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol. 2014; 233(3): 308-318.
    • (2014) J Pathol , vol.233 , Issue.3 , pp. 308-318
    • Liu, G.1    Sun, Y.2    Ji, P.3    Li, X.4    Cogdell, D.5    Yang, D.6
  • 37
    • 84896702481 scopus 로고    scopus 로고
    • Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development
    • Mazan-Mamczarz K, Zhao XF, Dai B, Steinhardt JJ, Peroutka RJ, Berk KL, et al. Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development. PLoS Genet. 2014; 10(1): e1004105.
    • (2014) PLoS Genet , vol.10 , Issue.1
    • Mazan-Mamczarz, K.1    Zhao, X.F.2    Dai, B.3    Steinhardt, J.J.4    Peroutka, R.J.5    Berk, K.L.6
  • 38
    • 84876895426 scopus 로고    scopus 로고
    • Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels
    • Bozdag S, Li A, Riddick G, Kotliarov Y, Baysan M, Iwamoto FM, et al. Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels. PLoS One. 2013; 8(4): e62982.
    • (2013) PLoS One , vol.8 , Issue.4
    • Bozdag, S.1    Li, A.2    Riddick, G.3    Kotliarov, Y.4    Baysan, M.5    Iwamoto, F.M.6
  • 39
    • 84878115461 scopus 로고    scopus 로고
    • Aging epigenetics: Causes and consequences
    • Huidobro C, Fernandez AF, Fraga MF. Aging epigenetics: causes and consequences. Mol Aspects Med. 2013; 34(4): 765-781.
    • (2013) Mol Aspects Med , vol.34 , Issue.4 , pp. 765-781
    • Huidobro, C.1    Fernandez, A.F.2    Fraga, M.F.3
  • 40
    • 84894549802 scopus 로고    scopus 로고
    • MicroRNA mediates DNA methylation of target genes
    • Hu W, Wang T, Xu J, Li H. MicroRNA mediates DNA methylation of target genes. Biochem Biophys Res Commun. 2014; 444(4): 676-681.
    • (2014) Biochem Biophys Res Commun , vol.444 , Issue.4 , pp. 676-681
    • Hu, W.1    Wang, T.2    Xu, J.3    Li, H.4
  • 41
    • 79955807556 scopus 로고    scopus 로고
    • Histone modification profles are predictive for tissue/cell-type specific expression of both protein-coding and microRNA genes
    • Zhang Z, Zhang MQ. Histone modification profles are predictive for tissue/cell-type specific expression of both protein-coding and microRNA genes. BMC Bioinformatics. 2011; 12: 155.
    • (2011) BMC Bioinformatics , vol.12 , pp. 155
    • Zhang, Z.1    Zhang, M.Q.2
  • 43
    • 84904342321 scopus 로고    scopus 로고
    • Epigenetic inactivation of DAPK1, p14ARF, mir-34a and-34b/c in acute promyelocytic Leukaemia
    • Ng HY, Wan TS, So CC, Chim CS. Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukaemia. J Clin Pathol. 2014; 67(7): 626-631.
    • (2014) J Clin Pathol , vol.67 , Issue.7 , pp. 626-631
    • Ng, H.Y.1    Wan, T.S.2    So, C.C.3    Chim, C.S.4
  • 44
    • 84899646114 scopus 로고    scopus 로고
    • Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer
    • Xie K, Liu J, Chen J, Dong J, Ma H, Liu Y, et al. Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer. Gene. 2014; 543(1): 101-107.
    • (2014) Gene , vol.543 , Issue.1 , pp. 101-107
    • Xie, K.1    Liu, J.2    Chen, J.3    Dong, J.4    Ma, H.5    Liu, Y.6
  • 46
    • 84896739532 scopus 로고    scopus 로고
    • Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): A randomised controlled non-inferiority trial
    • Verhoef VM, Bosgraaf RP, van Kemenade FJ, Rozendaal L, Heideman DA, Hesselink AT, et al. Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised controlled non-inferiority trial. Lancet Oncol. 2014; 15(3): 315-322.
    • (2014) Lancet Oncol , vol.15 , Issue.3 , pp. 315-322
    • Verhoef, V.M.1    Bosgraaf, R.P.2    Van Kemenade, F.J.3    Rozendaal, L.4    Heideman, D.A.5    Hesselink, A.T.6
  • 47
    • 84894521534 scopus 로고    scopus 로고
    • Epigenetic silencing of MicroRNA-503 regulates FANCA expression in non-small cell lung cancer cell
    • Li N, Zhang F, Li S, Zhou S. Epigenetic silencing of MicroRNA-503 regulates FANCA expression in non-small cell lung cancer cell. Biochem Biophys Res Commun. 2014; 444(4): 611-616.
    • (2014) Biochem Biophys Res Commun , vol.444 , Issue.4 , pp. 611-616
    • Li, N.1    Zhang, F.2    Li, S.3    Zhou, S.4
  • 48
    • 84902976439 scopus 로고    scopus 로고
    • Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease
    • Ben Gacem R, Ben Abdelkrim O, Ziadi S, Ben Dhiab M, Trimeche M. Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease. Tumour Biol. 2014; 35(5): 4047-4056.
    • (2014) Tumour Biol. , vol.35 , Issue.5 , pp. 4047-4056
    • Ben Gacem, R.1    Ben Abdelkrim, O.2    Ziadi, S.3    Ben Dhiab, M.4    Trimeche, M.5
  • 49
    • 84891000645 scopus 로고    scopus 로고
    • Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic Leukemia-implications on constitutive activation of NFκB pathway
    • Wang LQ, Kwong YL, Kho CS, Wong KF, Wong KY, Ferracin M, et al. Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia-implications on constitutive activation of NFκB pathway. Mol Cancer. 2013; 12: 173.
    • (2013) Mol Cancer , vol.12 , pp. 173
    • Wang, L.Q.1    Kwong, Y.L.2    Kho, C.S.3    Wong, K.F.4    Wong, K.Y.5    Ferracin, M.6
  • 50
    • 84891667199 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia Jurkat cells by modulating expression of fas-associated protein with death domain (FADD)
    • Yamada N, Noguchi S, Kumazaki M, Shinohara H, Miki K, Naoe T, et al. Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia jurkat cells by modulating expression of fas-associated protein with death domain (FADD). Biochim Biophys Acta. 2014; 1843(3): 590-602.
    • (2014) Biochim Biophys Acta , vol.1843 , Issue.3 , pp. 590-602
    • Yamada, N.1    Noguchi, S.2    Kumazaki, M.3    Shinohara, H.4    Miki, K.5    Naoe, T.6
  • 51
    • 84890710331 scopus 로고    scopus 로고
    • Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma
    • Nadal E, Chen G, Gallegos M, Lin L, Ferrer-Torres D, Truini A, et al. Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma. Clin Cancer Res. 2013; 19(24): 6842-6852.
    • (2013) Clin Cancer Res , vol.19 , Issue.24 , pp. 6842-6852
    • Nadal, E.1    Chen, G.2    Gallegos, M.3    Lin, L.4    Ferrer-Torres, D.5    Truini, A.6
  • 52
    • 84884557234 scopus 로고    scopus 로고
    • Methylation regulation of liver-specific microRNA-122 expression and its effects on the proliferation and apoptosis of hepatocellular carcinoma cells
    • Xing TJ, Xu HT, Yu WQ, Jiang DF. Methylation regulation of liver-specific microRNA-122 expression and its effects on the proliferation and apoptosis of hepatocellular carcinoma cells. Genet Mol Res. 2013; 12(3): 3588-3597.
    • (2013) Genet Mol Res. , vol.12 , Issue.3 , pp. 3588-3597
    • Xing, T.J.1    Xu, H.T.2    Yu, W.Q.3    Jiang, D.F.4
  • 53
    • 84884249032 scopus 로고    scopus 로고
    • Hyper-methylated miR-203 dysregulates ABL1 and contributes to the nickel-induced tumorigenesis
    • Zhang J, Zhou Y, Wu YJ, Li MJ, Wang RJ, Huang SQ, et al. Hyper-methylated miR-203 dysregulates ABL1 and contributes to the nickel-induced tumorigenesis. Toxicol Lett. 2013; 223(1): 42-51.
    • (2013) Toxicol Lett. , vol.223 , Issue.1 , pp. 42-51
    • Zhang, J.1    Zhou, Y.2    Wu, Y.J.3    Li, M.J.4    Wang, R.J.5    Huang, S.Q.6
  • 54
    • 84882686726 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer
    • Zhang Y, Wang X, Xu B, Wang B, Wang Z, Liang Y, et al. Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer. Oncol Rep. 2013; 30(4): 1976-1984.
    • (2013) Oncol Rep. , vol.30 , Issue.4 , pp. 1976-1984
    • Zhang, Y.1    Wang, X.2    Xu, B.3    Wang, B.4    Wang, Z.5    Liang, Y.6
  • 56
    • 84909594668 scopus 로고    scopus 로고
    • miR-326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression
    • Hong CC, Chen PS, Chiou J, Chiu CF, Yang CY, Hsiao M, et al. miR-326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression. Cancer Res. 2014; 74(21): 6280-6290.
    • (2014) Cancer Res. , vol.74 , Issue.21 , pp. 6280-6290
    • Hong, C.C.1    Chen, P.S.2    Chiou, J.3    Chiu, C.F.4    Yang, C.Y.5    Hsiao, M.6
  • 57
    • 84907504237 scopus 로고    scopus 로고
    • miR-375 suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal squamous cell carcinoma
    • Luo J, Wu J, Li Z, Qin H, Wang B, Wong TS, et al. miR-375 Suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal squamous cell carcinoma. Biomed Res Int. 2014; 2014: 374598.
    • (2014) Biomed Res Int. , vol.2014
    • Luo, J.1    Wu, J.2    Li, Z.3    Qin, H.4    Wang, B.5    Wong, T.S.6
  • 58
    • 84907286869 scopus 로고    scopus 로고
    • MicroRNA-497 suppresses angiogenesis by targeting vascular endothelial growth factor A through the PI3K/AKT and MAPK/ERK pathways in ovarian cancer
    • Wang W, Ren F, Wu Q, Jiang D, Li H, Shi H. MicroRNA-497 suppresses angiogenesis by targeting vascular endothelial growth factor A through the PI3K/AKT and MAPK/ERK pathways in ovarian cancer. Oncol Rep. 2014; 32(5): 2127-2133.
    • (2014) Oncol Rep. , vol.32 , Issue.5 , pp. 2127-2133
    • Wang, W.1    Ren, F.2    Wu, Q.3    Jiang, D.4    Li, H.5    Shi, H.6
  • 60
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer. 2006; 6(11): 857-866.
    • (2006) Nat Rev Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 62
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, et al. Unique microRNA molecular profles in lung cancer diagnosis and prognosis. Cancer Cell. 2006; 9(3): 189-198.
    • (2006) Cancer Cell. , vol.9 , Issue.3 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4    Kumamoto, K.5    Yi, M.6
  • 63
    • 84949959109 scopus 로고    scopus 로고
    • Mirnas as diagnostic and prognostic biomarkers in pancreatic ductal adenocarcinoma and its precursor lesions: A review
    • Alemar B, Gregorio C, Ashton-Prolla P. miRNAs as diagnostic and prognostic biomarkers in pancreatic ductal adenocarcinoma and its precursor lesions: a review. Biomark Insights. 2015; 10: 113-124.
    • (2015) Biomark Insights , vol.10 , pp. 113-124
    • Alemar, B.1    Gregorio, C.2    Ashton-Prolla, P.3
  • 64
    • 84869866890 scopus 로고    scopus 로고
    • MicroRNA and cancer
    • Jansson MD, Lund AH. MicroRNA and cancer. Mol Oncol. 2012; 6(6): 590-610.
    • (2012) Mol Oncol , vol.6 , Issue.6 , pp. 590-610
    • Jansson, M.D.1    Lund, A.H.2
  • 65
    • 33846188098 scopus 로고    scopus 로고
    • Micrornas as oncogenes and tumor suppressors
    • Zhang B, Pan X, Cobb GP, Anderson TA. microRNAs as oncogenes and tumor suppressors. Dev Biol. 2007; 302(1): 1-12.
    • (2007) Dev Biol. , vol.302 , Issue.1 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 66
    • 33749507943 scopus 로고    scopus 로고
    • A small piece in the cancer puzzle: Micrornas as tumor suppressors and oncogenes
    • Kent OA, Mendell JT. A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene. 2006; 25(46): 6188-6196.
    • (2006) Oncogene , vol.25 , Issue.46 , pp. 6188-6196
    • Kent, O.A.1    Mendell, J.T.2
  • 68
    • 84919905013 scopus 로고    scopus 로고
    • Association between a functional polymorphism rs712 within let-7-binding site and risk of papillary thyroid cancer
    • Jin H, Liang Y, Wang X, Zhu J, Sun R, Chen P, et al. Association between a functional polymorphism rs712 within let-7-binding site and risk of papillary thyroid cancer. Med Oncol. 2014; 31(10): 221.
    • (2014) Med Oncol , vol.31 , Issue.10 , pp. 221
    • Jin, H.1    Liang, Y.2    Wang, X.3    Zhu, J.4    Sun, R.5    Chen, P.6
  • 69
    • 84863526543 scopus 로고    scopus 로고
    • Molecular medicine and the development of cancer chemopreventive agents
    • Izzotti A. Molecular medicine and the development of cancer chemopreventive agents. Ann NY Acad Sci. 2012; 1259: 26-32.
    • (2012) Ann NY Acad Sci. , vol.1259 , pp. 26-32
    • Izzotti, A.1
  • 70
    • 84862877840 scopus 로고    scopus 로고
    • High let-7a microRNA levels in KRASmutated colorectal carcinomas May rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease
    • Ruzzo A, Graziano F, Vincenzi B, Canestrari E, Perrone G, Galluccio N, et al. High let-7a microRNA levels in KRASmutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. Oncologist. 2012; 17(6): 823-829.
    • (2012) Oncologist , vol.17 , Issue.6 , pp. 823-829
    • Ruzzo, A.1    Graziano, F.2    Vincenzi, B.3    Canestrari, E.4    Perrone, G.5    Galluccio, N.6
  • 73
    • 35548957247 scopus 로고    scopus 로고
    • Micrornas join the p53 network-another piece in the tumour-suppression puzzle
    • He L, He X, Lowe SW, Hannon GJ. microRNAs join the p53 network-another piece in the tumour-suppression puzzle. Nat Rev Cancer. 2007; 7(11): 819-822.
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 819-822
    • He, L.1    He, X.2    Lowe, S.W.3    Hannon, G.J.4
  • 74
    • 84876491657 scopus 로고    scopus 로고
    • MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation
    • Liang Z, Ahn J, Guo D, Votaw JR, Shim H. MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation. Pharm Res. 2013; 30(4): 1008-1016.
    • (2013) Pharm Res. , vol.30 , Issue.4 , pp. 1008-1016
    • Liang, Z.1    Ahn, J.2    Guo, D.3    Votaw, J.R.4    Shim, H.5
  • 75
    • 84900969667 scopus 로고    scopus 로고
    • The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense
    • Itahana Y, Han R, Barbier S, Lei Z, Rozen S, Itahana K. The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. Oncogene. 2015; 34(14): 1799-1810.
    • (2015) Oncogene , vol.34 , Issue.14 , pp. 1799-1810
    • Itahana, Y.1    Han, R.2    Barbier, S.3    Lei, Z.4    Rozen, S.5    Itahana, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.