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Volumn 35, Issue 5, 2014, Pages 4047-4056

Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease

Author keywords

Breast cancer; Methylation; MicroRNA

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HORMONE RECEPTOR; MICRORNA; MICRORNA 124A 1; MICRORNA 124A 2; MICRORNA 124A 3; UNCLASSIFIED DRUG; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; MIRN124 MICRORNA, HUMAN;

EID: 84902976439     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1530-4     Document Type: Article
Times cited : (41)

References (35)
  • 1
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • DOI 10.1038/sj.onc.1205600
    • Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene. 2002;21:5427-40. (Pubitemid 34983479)
    • (2002) Oncogene , vol.21 , Issue.35 REV. ISS. 3 , pp. 5427-5440
    • Esteller, M.1
  • 3
    • 0033919595 scopus 로고    scopus 로고
    • DNMT1 forms a complex with RB, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
    • DOI 10.1038/77124
    • Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet. 2000;25:338-42. (Pubitemid 30437325)
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 338-342
    • Robertson, K.D.1    Ait-Si-Ali, S.2    Yokochi, T.3    Wade, P.A.4    Jones, P.L.5    Wolffe, A.P.6
  • 4
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • DOI 10.1016/S0092-8674(00)81656-6
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999;99:247-57. (Pubitemid 29519904)
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 5
    • 46449115224 scopus 로고    scopus 로고
    • The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer
    • Ding WJ, Fang JY, Chen XY, Peng YS. The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer. Dig Dis Sci. 2008;53:2083-9.
    • (2008) Dig Dis Sci , vol.53 , pp. 2083-2089
    • Ding, W.J.1    Fang, J.Y.2    Chen, X.Y.3    Peng, Y.S.4
  • 7
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • DOI 10.1038/nature02871
    • Ambros V. The functions of animal microRNAs. Nature. 2004;431:350-5. (Pubitemid 39265675)
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 8
    • 33645294070 scopus 로고    scopus 로고
    • OncomiRs-microRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ. OncomiRs-microRNAs with a role in cancer. Nat Rev Cancer. 2006;6:259-69.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 9
    • 34247555491 scopus 로고    scopus 로고
    • MicroRNAs as tumor suppressors
    • DOI 10.1038/ng0507-582, PII NG0507582
    • Hammond SM. MicroRNAs as tumor suppressors. Nat Genet. 2007;39:582-3. (Pubitemid 46676097)
    • (2007) Nature Genetics , vol.39 , Issue.5 , pp. 582-583
    • Hammond, S.M.1
  • 10
    • 48949116262 scopus 로고    scopus 로고
    • miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
    • Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BCM Med. 2008;6:14-31.
    • (2008) BCM Med , vol.6 , pp. 14-31
    • Silber, J.1    Lim, D.A.2    Petritsch, C.3    Persson, A.I.4    Maunakea, A.K.5    Yu, M.6
  • 11
    • 64249160168 scopus 로고    scopus 로고
    • DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect
    • Ando T, Yoshida T, Enomoto S, Asada K, Tatematsu M, Ichinose M, et al. DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect. Int J Cancer. 2009;124(10):2367-74.
    • (2009) Int J Cancer , vol.124 , Issue.10 , pp. 2367-2374
    • Ando, T.1    Yoshida, T.2    Enomoto, S.3    Asada, K.4    Tatematsu, M.5    Ichinose, M.6
  • 12
    • 66249148694 scopus 로고    scopus 로고
    • Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
    • Agirre X, Vilas-Zornoza A, Jiménez-Velasco A, Martin-Subero JI, Cordeu L, Gárate L, et al. Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia. Cancer Res. 2009;69:4443-53.
    • (2009) Cancer Res , vol.69 , pp. 4443-4453
    • Agirre, X.1    Vilas-Zornoza, A.2    Jiménez-Velasco, A.3    Martin-Subero, J.I.4    Cordeu, L.5    Gárate, L.6
  • 14
    • 77952299722 scopus 로고    scopus 로고
    • miR-124 andmiR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
    • Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J. miR-124 andmiR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis. 2010;31:766-76.
    • (2010) Carcinogenesis , vol.31 , pp. 766-776
    • Furuta, M.1    Kozaki, K.I.2    Tanaka, S.3    Arii, S.4    Imoto, I.5    Inazawa, J.6
  • 16
    • 79955526497 scopus 로고    scopus 로고
    • Epigenetic inactivation of the miR-124-1 in haematological malignancies
    • Wong KY, So CC, Loong F, Chung LP, Lam WW, Liang R, et al. Epigenetic inactivation of the miR-124-1 in haematological malignancies. PLoS One. 2011;6(4):e19027.
    • (2011) PLoS One , vol.6 , Issue.4
    • Wong, K.Y.1    So, C.C.2    Loong, F.3    Chung, L.P.4    Lam, W.W.5    Liang, R.6
  • 17
    • 84875641477 scopus 로고    scopus 로고
    • MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma
    • Chen X, He D, Dong XD, Dong F, Wang J, Wang L, et al. MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma. Invest Ophthalmol Vis Sci. 2013;54:2248-56.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 2248-2256
    • Chen, X.1    He, D.2    Dong, X.D.3    Dong, F.4    Wang, J.5    Wang, L.6
  • 18
    • 84871067207 scopus 로고    scopus 로고
    • MiR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro
    • Lv XB, Jiao Y, Qing Y, Hu H, Cui X, Lin T, et al. MiR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro. Chin J Cancer. 2011;30(12):821-30.
    • (2011) Chin J Cancer , vol.30 , Issue.12 , pp. 821-830
    • Lv, X.B.1    Jiao, Y.2    Qing, Y.3    Hu, H.4    Cui, X.5    Lin, T.6
  • 19
    • 84874787674 scopus 로고    scopus 로고
    • MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer
    • Liang YJ, Wang QY, Zhou CX, Yin QQ, He M, Yu XT, et al. MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer. Carcinogenesis. 2013;34(3):713-22.
    • (2013) Carcinogenesis , vol.34 , Issue.3 , pp. 713-722
    • Liang, Y.J.1    Wang, Q.Y.2    Zhou, C.X.3    Yin, Q.Q.4    He, M.5    Yu, X.T.6
  • 20
    • 78751486369 scopus 로고    scopus 로고
    • MicroRNA-124a and microRNA-34b/c are frequentlymethylated in all histological types of colorectal cancer and polyps, and in the adjacent normal mucosa
    • Deng G, Kakar S, Kim YS. MicroRNA-124a and microRNA-34b/c are frequentlymethylated in all histological types of colorectal cancer and polyps, and in the adjacent normal mucosa. Oncol Lett. 2011;2(1):175-80.
    • (2011) Oncol Lett , vol.2 , Issue.1 , pp. 175-180
    • Deng, G.1    Kakar, S.2    Kim, Y.S.3
  • 21
    • 0000055417 scopus 로고    scopus 로고
    • Role of pathology in the prognosis and management of breast cancer
    • Elston CW, Ellis IO, editors. 3rd ed. Edinburgh: Churchill Livingstone
    • Elston CW, Ellis IO, Goulging H, Pindre SE. Role of pathology in the prognosis and management of breast cancer. In: Elston CW, Ellis IO, editors. Systemic pathology, vol. 13. 3rd ed. Edinburgh: Churchill Livingstone; 1998. p. 385-433.
    • (1998) Systemic Pathology , vol.13 , pp. 385-433
    • Elston, C.W.1    Ellis, I.O.2    Goulging, H.3    Pindre, S.E.4
  • 22
  • 24
    • 84858796750 scopus 로고    scopus 로고
    • Contribution of epigenetic alteration of BRCA1 and BRCA2 genes in breast carcinomas in Tunisian patients
    • Ben Gacem R, Hachana M, Ziadi S, Amara K, Ksia F, Mokni M, et al. Contribution of epigenetic alteration of BRCA1 and BRCA2 genes in breast carcinomas in Tunisian patients. Cancer Epidemiol. 2012;36:190-7.
    • (2012) Cancer Epidemiol , vol.36 , pp. 190-197
    • Ben Gacem, R.1    Hachana, M.2    Ziadi, S.3    Amara, K.4    Ksia, F.5    Mokni, M.6
  • 26
    • 7744230268 scopus 로고    scopus 로고
    • Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease
    • Singal R, Ferdinand L, Reis IM, Schlesselman JJ. Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease. Oncol Rep. 2004;12:631-7.
    • (2004) Oncol Rep , vol.12 , pp. 631-637
    • Singal, R.1    Ferdinand, L.2    Reis, I.M.3    Schlesselman, J.J.4
  • 27
    • 84866501823 scopus 로고    scopus 로고
    • Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers
    • Ben Gacem R, Hachana M, Ziadi S, Ben Abdelkarim S, Hidar S, Trimeche M. Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers. Hum Pathol. 2012;43:1731-8.
    • (2012) Hum Pathol , vol.43 , pp. 1731-1738
    • Ben Gacem, R.1    Hachana, M.2    Ziadi, S.3    Ben Abdelkarim, S.4    Hidar, S.5    Trimeche, M.6
  • 28
    • 0037255729 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases in multistep hepatocarcinogenesis
    • DOI 10.1053/hupa.2003.5
    • Choi MS, Shim YH, Hwa JY, Lee SK, Ro JY, Kim JS, et al. Expression of DNA methyltransferases in multistep hepatocarcinogenesis. Hum Pathol. 2003;34:11-7. (Pubitemid 36160016)
    • (2003) Human Pathology , vol.34 , Issue.1 , pp. 11-17
    • Choi, M.S.1    Shim, Y.-H.2    Hwa, J.Y.3    Lee, S.K.4    Ro, J.Y.5    Kim, J.-S.6    Yu, E.7
  • 29
    • 33144460031 scopus 로고    scopus 로고
    • Beyond the cell cycle: A new role for cdk6 in differentiation
    • DOI 10.1002/jcb.20712
    • Grossel MJ, Hinds PW. Beyond the cell cycle: a new role for Cdk6 in differentiation. J Cell Biochem. 2006;97:485-93. (Pubitemid 43265308)
    • (2006) Journal of Cellular Biochemistry , vol.97 , Issue.3 , pp. 485-493
    • Grossel, M.J.1    Hinds, P.W.2
  • 30
    • 80755159538 scopus 로고    scopus 로고
    • MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer
    • Peurala H, Greco D, Heikkinen T, Kaur S, Bartkova J, Jamshidi M, et al. MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer. PLoS One. 2011;6:e26122.
    • (2011) PLoS One , vol.6
    • Peurala, H.1    Greco, D.2    Heikkinen, T.3    Kaur, S.4    Bartkova, J.5    Jamshidi, M.6
  • 31
    • 84862506981 scopus 로고    scopus 로고
    • MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status
    • Zhou X, Marian C, Makambi KH, Kosti O, Kallakury BV, Loffredo CA, et al. MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status. PLoS One. 2012;7(6):e39011.
    • (2012) PLoS One , vol.7 , Issue.6
    • Zhou, X.1    Marian, C.2    Makambi, K.H.3    Kosti, O.4    Kallakury, B.V.5    Loffredo, C.A.6
  • 32
    • 31544456085 scopus 로고    scopus 로고
    • The role of mammalian DNA methyltransferases in the regulation of gene expression
    • Turek-Plewa J, Jagodziński PP. The role of mammalian DNA methyltransferases in the regulation of gene expression. Cell Mol Biol Lett. 2005;10(4):631-47. (Pubitemid 43161688)
    • (2005) Cellular and Molecular Biology Letters , vol.10 , Issue.4 , pp. 631-647
    • Turek-Plewa, J.1    Jagodzinski, P.P.2
  • 33
    • 39649104991 scopus 로고    scopus 로고
    • DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
    • Roll JD, Rivenbark AG, Jones WD, Coleman WB. DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol Cancer. 2008;7:15.
    • (2008) Mol Cancer , vol.7 , pp. 15
    • Roll, J.D.1    Rivenbark, A.G.2    Jones, W.D.3    Coleman, W.B.4
  • 34
    • 77950867869 scopus 로고    scopus 로고
    • Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells
    • Billam M, Sobolewski MD, Davidson NE. Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. Breast Cancer Res Treat. 2010;120:581-92.
    • (2010) Breast Cancer Res Treat , vol.120 , pp. 581-592
    • Billam, M.1    Sobolewski, M.D.2    Davidson, N.E.3
  • 35
    • 84874306245 scopus 로고    scopus 로고
    • A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1
    • Xu Q, Jiang Y, Yin Y, Li Q, He J, Jing Y, et al. A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1. J Mol Cell Biol. 2013;5:3-13.
    • (2013) J Mol Cell Biol , vol.5 , pp. 3-13
    • Xu, Q.1    Jiang, Y.2    Yin, Y.3    Li, Q.4    He, J.5    Jing, Y.6


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