Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia Jurkat cells by modulating expression of Fas-associated protein with death domain (FADD)

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1843, Issue 3, 2014, Pages 590-602

  Yamada, Nami ^a   Noguchi, Shunsuke ^a   Kumazaki, Minami ^a   Shinohara, Haruka ^a   Miki, Kohei ^a   Naoe, Tomoki ^b   Akao, Yukihiro ^a  

^a GIFU UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis resistance; DNA methylation; FADD; MiR 128a; T cell leukaemia

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 8; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; MICRORNA; MICRORNA 128A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; ELECTROPORATION; EPIGENETICS; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; WESTERN BLOTTING;

ANTIGENS, CD95; APOPTOSIS; CELL LINE, TUMOR; DNA METHYLATION; EPIGENESIS, GENETIC; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE EXPRESSION; HL-60 CELLS; HUMANS; JURKAT CELLS; K562 CELLS; LEUKEMIA, T-CELL; MICRORNAS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84891667199     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.11.022     Document Type: Article

References (30)

1. Kloosterman W.P., Plasterk R.H. The diverse functions of microRNAs in animal development and disease. Dev. Cell 2006, 11:441-450.
2. Mendell J.T. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle 2005, 4:1179-1184.
3. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
4. Iorio M.V., Croce C.M. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med 2012, 4:143-159.
5. Esquela-Kerscher A., Slack F.J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6:259-269.
6. Calin G.A., Liu C.G., Ferracin M., Hyslop T., Spizzo R., Sevignani C., Fabbri M., Cimmino A., Lee E.J., Wojcik S.E., Shimizu M., Tili E., Rossi S., Taccioli C., Pichiorri F., Liu X., Zupo S., Herlea V., Gramantieri L., Lanza G., Alder H., Rassenti L., Volinia S., Schmittgen T.D., Kipps T.J., Negrini M., Croce C.M. Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer cell 2007, 12:215-229.
7. Calin G.A., Sevignani C., Dumitru C.D., Hyslop T., Noch E., Yendamuri S., Shimizu M., Rattan S., Bullrich F., Negrini M., Croce C.M. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:2999-3004.
8. Kohler C.U., Bryk O., Meier S., Lang K., Rozynek P., Bruning T., Kafferlein H.U. Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers. Biochem. Biophys. Res. Commun. 2013, 438:48-53.
9. Menigatti M., Staiano T., Manser C.N., Bauerfeind P., Komljenovic A., Robinson M., Jiricny J., Buffoli F., Marra G. Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions. Oncogenesis 2013, 2:e56.
10. Yan-Fang T., Jian N., Jun L., Na W., Pei-Fang X., Wen-Li Z., Dong W., Li P., Jian W., Xing F., Jian P. The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML). BMC Med. Genet. 2013, 14:74.
11. Mi S., Lu J., Sun M., Li Z., Zhang H., Neilly M.B., Wang Y., Qian Z., Jin J., Zhang Y., Bohlander S.K., Le Beau M.M., Larson R.A., Golub T.R., Rowley J.D., Chen J. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:19971-19976.
12. Zhu Y.D., Wang L., Sun C., Fan L., Zhu D.X., Fang C., Wang Y.H., Zou Z.J., Zhang S.J., Li J.Y., Xu W. Distinctive microRNA signature is associated with the diagnosis and prognosis of acute leukemia. Med. Oncol. 2012, 29:2323-2331.
13. Godlewski J., Nowicki M.O., Bronisz A., Williams S., Otsuki A., Nuovo G., Raychaudhury A., Newton H.B., Chiocca E.A., Lawler S. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res. 2008, 68:9125-9130.
14. Lessard J., Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003, 423:255-260.
15. Peter M.E., Budd R.C., Desbarats J., Hedrick S.M., Hueber A.O., Newell M.K., Owen L.B., Pope R.M., Tschopp J., Wajant H., Wallach D., Wiltrout R.H., Zornig M., Lynch D.H. The CD95 receptor: apoptosis revisited. Cell 2007, 129:447-450.
16. Beltinger C., Kurz E., Bohler T., Schrappe M., Ludwig W.D., Debatin K.M. CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia. Blood 1998, 91:3943-3951.
17. Yeh W.C., de la Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., Ng M., Wakeham A., Khoo W., Mitchell K., El-Deiry W.S., Lowe S.W., Goeddel D.V., Mak T.W. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998, 279:1954-1958.
18. Zhang J., Cado D., Chen A., Kabra N.H., Winoto A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 1998, 392:296-300.
19. Lynam-Lennon N., Maher S.G., Reynolds J.V. The roles of microRNA in cancer and apoptosis. Biol. Rev. Camb. Philos. Soc. 2009, 84:55-71.
20. Chen L., Tang Y., Wang J., Yan Z., Xu R. miR-421 Induces Cell Proliferation and Apoptosis Resistance in human Nasopharyngeal Carcinoma via Downregulation of FOXO4. Biochem. Biophys. Res. Commun. 2013, 435:745-750.
21. Korner C., Keklikoglou I., Bender C., Worner A., Munstermann E., Wiemann S. MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon). J. Biol. Chem. 2013, 288:8750-8761.
22. Akao Y., Nakagawa Y., Hirata I., Iio A., Itoh T., Kojima K., Nakashima R., Kitade Y., Naoe T. Role of anti-oncomirs miR-143 and -145 in human colorectal tumors. Cancer Gene Ther. 2010, 17:398-408.
23. Noguchi S., Mori T., Otsuka Y., Yamada N., Yasui Y., Iwasaki J., Kumazaki M., Maruo K., Akao Y. Anti-oncogenic microRNA-203 induces senescence by targeting E2F3 protein in human melanoma cells. J. Biol. Chem. 2012, 287:11769-11777.
24. Yamada N., Noguchi S., Mori T., Naoe T., Maruo K., Akao Y. Tumor-suppressive microRNA-145 targets catenin delta-1 to regulate Wnt/beta-catenin signaling in human colon cancer cells. Cancer Lett. 2013, 335:332-342.
25. Herman J.G., Graff J.R., Myohanen S., Nelkin B.D., Baylin S.B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:9821-9826.
26. Shirley S., Micheau O. Targeting c-FLIP in Cancer. Cancer Lett. 2013, 332:141-150.
27. Kischkel F.C., Lawrence D.A., Tinel A., LeBlanc H., Virmani A., Schow P., Gazdar A., Blenis J., Arnott D., Ashkenazi A. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J. Biol. Chem. 2001, 276:46639-46646.
28. Myatt S.S., Wang J., Monteiro L.J., Christian M., Ho K.K., Fusi L., Dina R.E., Brosens J.J., Ghaem-Maghami S., Lam E.W. Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer. Cancer Res. 2010, 70:367-377.
29. Zhu Y., Yu F., Jiao Y., Feng J., Tang W., Yao H., Gong C., Chen J., Su F., Zhang Y., Song E. Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin. Cancer Res. 2011, 17:7105-7115.
30. Tourneur L., Chiocchia G. FADD: a regulator of life and death. Trends Immunol. 2010, 31:260-269.