The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873

Cell Death and Differentiation

Volumn 23, Issue 8, 2016, Pages 1394-1405

  Wang, K ^a   Liu, F ^b   Liu, C Y ^a   An, T ^c   Zhang, J ^c   Zhou, L Y ^a   Wang, M ^a   Dong, Y H ^a   Li, N ^a   Gao, J N ^a   Zhao, Y F ^a   Li, P F ^a  

^a QINGDAO UNIVERSITY   (China)

^b GUILIN MEDICAL UNIVERSITY   (China)

^c FUWAI HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LONG UNTRANSLATED RNA; MICRORNA; MICRORNA 873; NECROSIS RELATED FACTOR; PROTEIN KINASE; RECEPTOR INTERACTING SERINE THREONINE PROTEIN KINASE 1; RECEPTOR INTERACTING SERINE THREONINE PROTEIN KINASE 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ANTAGOMIR; HYDROGEN PEROXIDE; MIRN873 MICRORNA, MOUSE; PROTEIN P53; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELL DEATH; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE INJURY; HEART MUSCLE NECROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; 3' UNTRANSLATED REGION; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; MALE; METABOLISM; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROMOTER REGION; SEQUENCE ALIGNMENT; VETERINARY;

3' UNTRANSLATED REGIONS; ANIMALS; ANTAGOMIRS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PROMOTER REGIONS, GENETIC; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA, LONG NONCODING; SEQUENCE ALIGNMENT; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84976314156     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2016.28     Document Type: Article

References (68)

1. Cho YS, Park SY, Shin HS, Chan FK. Physiological consequences of programmed necrosis, an alternative form of cell demise. Mol Cells 2010; 29: 327-332
2. Lamkanfi M, Festjens N, Declercq W, Vanden Berghe T, Vandenabeele P. Caspases in cell survival, proliferation and differentiation. Cell Death Differ 2007; 14: 44-55
3. Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, et al. Cyclophilin d-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434: 652-658
4. Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, et al. Loss of cyclophilin d reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005; 434: 658-662
5. Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA, et al. Inhibition of rip1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Res Cardiol 2012; 107: 270
6. Kingma JG Jr, Yellon DM. Inability of dimethylthiourea to limit tissue necrosis during acute myocardial infarction in rabbits. Free Radic Biol Med 1992; 12: 263-270
7. Lissoni P, Pelizzoni F, Mauri O, Perego M, Pittalis S, Barni S. Enhanced secretion of tumour necrosis factor in patients with myocardial infarction. Eur J Med 1992; 1: 277-280
8. Bryant D, Becker L, Richardson J, Shelton J, Franco F, Peshock R, et al. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation 1998; 97: 1375-1381
9. Guerra S, Leri A, Wang X, Finato N, Di Loreto C, Beltrami CA, et al. Myocyte death in the failing human heart is gender dependent. Circ Res 1999; 85: 856-866
10. Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, et al. Phosphorylation-driven assembly of the rip1-rip3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137: 1112-1123
11. Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, et al. Rip3, an energy metabolism regulator that switches tnf-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-336
12. He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to tnf-alpha. Cell 2009; 137: 1100-1111
13. Sun L, Wang H, Wang Z, He S, Chen S, Liao D, et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of rip3 kinase. Cell 2012; 148: 213-227
14. Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M, et al. Rip3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction. Cardiovasc Res 2014; 103: 206-216
15. Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, et al. The nuclear rnase iii drosha initiates microrna processing. Nature 2003; 425: 415-419
16. Ohtani K, Dimmeler S. Control of cardiovascular differentiation by micrornas. Basic Res Cardiol 2011; 106: 5-11
17. Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D. Mir-24 inhibits apoptosis and represses bim in mouse cardiomyocytes. J Exp Med 2011; 208: 549-560
18. Wang X, Zhang X, Ren XP, Chen J, Liu H, Yang J, et al. Microrna-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury. Circulation 2010; 122: 1308-1318
19. Sayed D, He M, Hong C, Gao S, Rane S, Yang Z, et al. Microrna-21 is a downstream effector of akt that mediates its antiapoptotic effects via suppression of fas ligand. J Biol Chem 2010; 285: 20281-20290
20. Li P. Micrornas in cardiac apoptosis. J Cardiovasc Transl Res 2010; 3: 219-224
21. Basson M. Micrornas loom large in the heart. Nat Med 2007; 13: 541
22. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking mirna-1-2. Cell 2007; 129: 303-317
23. Yang B, Lin H, Xiao J, Lu Y, Luo X, Li B, et al. The muscle-specific microrna mir-1 regulates cardiac arrhythmogenic potential by targeting gja1 and kcnj2. Nat Med 2007; 13: 486-491
24. Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, et al. Micrornas in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 2007; 116: 258-267
25. Chien KR. Molecular medicine: micrornas and the tell-tale heart. Nature 2007; 447: 389-390
26. Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding rna hotair reprograms chromatin state to promote cancer metastasis. Nature 2010; 464: 1071-1076
27. Gong C, Maquat LE. Lncrnas transactivate stau1-mediated mrna decay by duplexing with 3? utrs via alu elements. Nature 2011; 470: 284-288
28. Clemson CM, Hutchinson JN, Sara SA, Ensminger AW, Fox AH, Chess A, et al. An architectural role for a nuclear noncoding rna: Neat1 rna is essential for the structure of paraspeckles. Mol Cell 2009; 33: 717-726
29. Khaitan D, Dinger ME, Mazar J, Crawford J, Smith MA, Mattick JS, et al. The melanomaupregulated long noncoding rna spry4-it1 modulates apoptosis and invasion. Cancer Res 2011; 71: 3852-3862
30. Ginger MR, Shore AN, Contreras A, Rijnkels M, Miller J, Gonzalez-Rimbau MF, et al. A noncoding rna is a potential marker of cell fate during mammary gland development. Proc Natl Acad Sci USA 2006; 103: 5781-5786
31. Archer K, Broskova Z, Bayoumi AS, Teoh JP, Davila A, Tang Y, et al. Long non-coding rnas as master regulators in cardiovascular diseases. Int J Mol Sci 2015; 16: 23651-23667
32. Ounzain S, Burdet F, Ibberson M, Pedrazzini T. Discovery and functional characterization of cardiovascular long noncoding rnas. J Mol Cell Cardiol 2015; 89: 17-26
33. Gao W, Wang ZM, Zhu M, Lian XQ, Zhao H, Zhao D, et al. Altered long noncoding rna expression profiles in the myocardium of rats with ischemic heart failure. J Cardiovasc Med (Hagerstown, MD) 2015; 16: 473-479
34. Pinet F, Bauters C. Potential of non-coding rna as biomarkers in heart failure. Med Sci (Paris) 2015; 31: 770-776
35. Gardner AM, Xu FH, Fady C, Jacoby FJ, Duffey DC, Tu Y, et al. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. Free Radic Biol Med 1997; 22: 73-83
36. Takeda M, Shirato I, Kobayashi M, Endou H. Hydrogen peroxide induces necrosis, apoptosis, oncosis and apoptotic oncosis of mouse terminal proximal straight tubule cells. Nephron 1999; 81: 234-238
37. Troyano A, Sancho P, Fernandez C, de Blas E, Bernardi P, Aller P. The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells. Cell Death Differ 2003; 10: 889-898
38. Downey JM. Free radicals and their involvement during long-term myocardial ischemia and reperfusion. Annu Rev Physiol 1990; 52: 487-504
39. Cesana M, Cacchiarelli D, Legnini I, Santini T, Sthandier O, Chinappi M, et al. A long noncoding rna controls muscle differentiation by functioning as a competing endogenous rna. Cell 2011; 147: 358-369
40. Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y, et al. Creb up-regulates long non-coding rna, hulc expression through interaction with microrna-372 in liver cancer. Nucleic Acids Res 2010; 38: 5366-5383
41. Cazalla D, Yario T, Steitz JA. Down-regulation of a host microrna by a herpesvirus saimiri noncoding rna. Science 2010; 328: 1563-1566
42. Liu X, He F, Pang R, Zhao D, Qiu W, Shan K, et al. Interleukin-17 (il-17)-induced microrna 873 (mir-873) contributes to the pathogenesis of experimental autoimmune encephalomyelitis by targeting a20 ubiquitin-editing enzyme. J Biol Chem 2014; 289: 28971-28986
43. Rahman S, Quann K, Pandya D, Singh S, Khan ZK, Jain P. Htlv-1 tax mediated downregulation of mirnas associated with chromatin remodeling factors in t cells with stably integrated viral promoter. PloS One 2012; 7: e34490
44. Skalsky RL, Cullen BR. Reduced expression of brain-enriched micrornas in glioblastomas permits targeted regulation of a cell death gene. PloS One 2011; 6: e24248
45. Morgan CP, Bale TL. Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. J Neurosci 2011; 31: 11748-11755
46. Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase rip as effector molecule. Nat Immunol 2000; 1: 489-495
47. Vercammen D, Beyaert R, Denecker G, Goossens V, Van Loo G, Declercq W, et al. Inhibition of caspases increases the sensitivity of l929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 1998; 187: 1477-1485
48. Remijsen Q, Goossens V, Grootjans S, Van den Haute C, Vanlangenakker N, Dondelinger Y, et al. Depletion of ripk3 or mlkl blocks tnf-driven necroptosis and switches towards a delayed ripk1 kinase-dependent apoptosis. Cell Death Dis 2014; 5: e1004
49. Eum HA, Vallabhaneni R, Wang Y, Loughran PA, Stolz DB, Billiar TR. Characterization of disc formation and tnfr1 translocation to mitochondria in tnf-alpha-treated hepatocytes. Am J Pathol 2011; 179: 1221-1229
50. Cusson N, Oikemus S, Kilpatrick ED, Cunningham L, Kelliher M. The death domain kinase rip protects thymocytes from tumor necrosis factor receptor type 2-induced cell death. J Exp Med 2002; 196: 15-26
51. Bellail AC, Tse MC, Song JH, Phuphanich S, Olson JJ, Sun SY, et al. Dr5-mediated disc controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas. J Cell Mol Med 2010; 14: 1303-1317
52. Kanduri C. Kcnq1ot1: a chromatin regulatory rna. Semin Cell Dev Biol 2011; 22: 343-350
53. Kumar MS, Armenteros-Monterroso E, East P, Chakravorty P, Matthews N, Winslow MM, et al. Hmga2 functions as a competing endogenous rna to promote lung cancer progression. Nature 2014; 505: 212-217
54. Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, et al. Silencing of micrornas in vivo with 'antagomirs. Nature 2005; 438: 685-689
55. Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, et al. Silencing microrna-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat Med 2012; 18: 1087-1094
56. Horwich MD, Zamore PD. Design and delivery of antisense oligonucleotides to block microrna function in cultured drosophila and human cells. Nat Protoc 2008; 3: 1537-1549
57. Wei C-L, Wu Q, Vega VB, Chiu KP, Ng P, Zhang T, et al. A global map of p53 transcriptionfactor binding sites in the human genome. Cell 2006; 124: 207-219
58. Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM. P53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell 2012; 149: 1536-1548
59. Furukawa A, Tada-Oikawa S, Kawanishi S, Oikawa S. H2o2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of sirt1 by nad+ depletion. Cell Physiol Biochem 2007; 20: 45-54
60. Wang Y-H, Tsay Y-G, Tan BC-M, Lo W-Y, Lee S-C. Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. J Biol Chem 2003; 278: 25568-25576
61. Xie S, Wang Q, Wu H, Cogswell J, Lu L, Jhanwar-Uniyal M, et al. Reactive oxygen speciesinduced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. J Biol Chem 2001; 276: 36194-36199
62. Uberti D, Yavin E, Gil S, Ayasola K-R, Goldfinger N, Rotter V. Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin. Mol Brain Res 1999; 65: 167-175
63. Long X, Goldenthal MJ, Marín-García J. Oxidative stress enhances phosphorylation of p53 in neonatal rat cardiomyocytes. Mol Cell Biochem 2007; 303: 167-174
64. Tan WQ, Wang K, Lv DY, Li PF. Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase. J Biol Chem 2008; 283: 29730-29739
65. Lin Z, Murtaza I, Wang K, Jiao J, Gao J, Li PF. Mir-23a functions downstream of nfatc3 to regulate cardiac hypertrophy. Proc Natl Acad Sci USA 2009; 106: 12103-12108
66. Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, Nguyen JT, et al. Real-time quantification of micrornas by stem-loop rt-pcr. Nucleic Acids Res 2005; 33: e179
67. Li PF, Dietz R, von Harsdorf R. P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by bcl-2. EMBO J 1999; 18: 6027-6036
68. Wang JX, Jiao JQ, Li Q, Long B, Wang K, Liu JP, et al. Mir-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med 2011; 17: 71-78