MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of fas ligand

Journal of Biological Chemistry

Volumn 285, Issue 26, 2010, Pages 20281-20290

  Sayed, Danish ^a   He, Minzhen ^a   Hong, Chull ^a   Gao, Shumin ^a   Rane, Shweta ^a,b   Yang, Zhi ^a   Abdellatif, Maha ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-APOPTOTIC EFFECTS; ANTIAPOPTOTIC; APOPTOSIS; CANCEROUS CELLS; CARDIAC MYOCYTES; CASPASES; DOMINANT-NEGATIVE MUTANTS; DOWN-REGULATION; FAS LIGAND; HEART FAILURE; INFARCT SIZE; MICRORNAS; MITOCHONDRIAL DAMAGE; OVER-EXPRESSION; PHOSPHATASE AND TENSIN HOMOLOGUES; TRANSGENIC MICE; UP-REGULATION; WORTMANNIN;

CELL DEATH; GROWTH KINETICS; PLANTS (BOTANY);

LIGANDS;

CASPASE 8; FAS LIGAND; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; ENZYME REPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HEMODYNAMICS; HYPOXIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

3' UNTRANSLATED REGIONS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELLS, CULTURED; FAS LIGAND PROTEIN; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICRORNAS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE;

MUS MUSCULUS;

EID: 77953782181     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.109207     Document Type: Article

References (47)

1. Volinia, S., Calin, G. A., Liu, C. G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., Prueitt, R. L., Yanaihara, N., Lanza, G., Scarpa, A., Vecchione, A., Negrini, M., Harris, C. C., and Croce, C. M. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 2257-2261
2. Meng, F., Henson, R., Wehbe-Janek, H., Ghoshal, K., Jacob, S. T., and Patel, T. (2007) Gastroenterology 133, 647-658
3. Zhu, S., Si, M. L., Wu, H., and Mo, Y. Y. (2007) J. Biol. Chem. 282, 14328-14336
4. Ji, R., Cheng, Y., Yue, J., Yang, J., Liu, X., Chen, H., Dean, D. B., and Zhang, C. (2007) Circ. Res. 100, 1579-1588
5. Meng, F., Henson, R., Lang, M., Wehbe, H., Maheshwari, S., Mendell, J. T., Jiang, J., Schmittgen, T. D., and Patel, T. (2006) Gastroenterology 130, 2113-2129
6. Asangani, I. A., Rasheed, S. A., Nikolova, D. A., Leupold, J. H., Colburn, N. H., Post, S., and Allgayer, H. (2008) Oncogene 27, 2128-2136
7. Frankel, L. B., Christoffersen, N. R., Jacobsen, A., Lindow, M., Krogh, A., and Lund, A. H. (2008) J. Biol. Chem. 283, 1026-1033
8. Li, Y., Li, W., Yang, Y., Lu, Y., He, C., Hu, G., Liu, H., Chen, J., He, J., and Yu, H. (2009) Brain Res. 1286, 13-18
9. Sayed, D., Hong, C., Chen, I. Y., Lypowy, J., and Abdellatif, M. (2007) Circ. Res. 100, 416-424
10. van Rooij, E., Sutherland, L. B., Liu, N., Williams, A. H., McAnally, J., Gerard, R. D., Richardson, J. A., and Olson, E. N. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 18255-18260
11. Tatsuguchi, M., Seok, H. Y., Callis, T. E., Thomson, J. M., Chen, J. F., Newman, M., Rojas, M., Hammond, S. M., and Wang, D. Z. (2007) J. Mol. Cell Cardiol. 42, 1137-1141
12. Cheng, Y., Ji, R., Yue, J., Yang, J., Liu, X., Chen, H., Dean, D. B., and Zhang, C. (2007) Am. J. Pathol. 170, 1831-1840
13. Thum, T., Gross, C., Fiedler, J., Fischer, T., Kissler, S., Bussen, M., Galuppo, P., Just, S., Rottbauer, W., Frantz, S., Castoldi, M., Soutschek, J., Koteliansky, V., Rosenwald, A., Basson, M. A., Licht, J. D., Pena, J. T., Rouhanifard, S. H., Muckenthaler, M. U., Tuschl, T., Martin, G. R., Bauersachs, J., and Engelhardt, S. (2008) Nature 456, 980-984
14. Roy, S., Khanna, S., Hussain, S. R., Biswas, S., Azad, A., Rink, C., Gnyawali, S., Shilo, S., Nuovo, G. J., and Sen, C. K. (2009) Cardiovasc. Res. 82, 21-29
15. Cheng, Y., Liu, X., Zhang, S., Lin, Y., Yang, J., and Zhang, C. (2009) J. Mol. Cell Cardiol. 47, 5-14
16. Dong, S., Cheng, Y., Yang, J., Li, J., Liu, X., Wang, X., Wang, D., Krall, T. J., Delphin, E. S., and Zhang, C. (2009) J. Biol. Chem. 284, 29514-29525
17. Hlobilková, A., Knillová, J., Bártek, J., Lukás, J., and Kolár, Z. (2003) Biomed. Pap Med. Fac. Univ. Palacky Olomouc. Czech. Repub. 147, 19-25
18. Leslie, N. R., Batty, I. H., Maccario, H., Davidson, L., and Downes, C. P. (2008) Oncogene 27, 5464-5476
19. Mocanu, M. M., and Yellon, D. M. (2007) Br. J. Pharmacol. 150, 833-838
20. Ruan, H., Li, J., Ren, S., Gao, J., Li, G., Kim, R., Wu, H., and Wang, Y. (2009) J. Mol. Cell Cardiol. 46, 193-200
21. Setsuta, K., Seino, Y., Ogawa, T., Ohtsuka, T., Seimiya, K., and Takano, T. (2004) Circ. J. 68, 747-750
22. Lee, P., Sata, M., Lefer, D. J., Factor, S. M., Walsh, K., and Kitsis, R. N. (2003) Am. J. Physiol. Heart Circ. Physiol. 284, H456-H463
23. Sayed, D., Rane, S., Lypowy, J., He, M., Chen, I. Y., Vashistha, H., Yan, L., Malhotra, A., Vatner, D., and Abdellatif, M. (2008) Mol. Biol. Cell 19, 3272-3282
24. Abdellatif, M., MacLellan, W. R., and Schneider, M. D. (1994) J. Biol. Chem. 269, 15423-15426
25. Graham, F. L., and Prevec, L. (1991) Methods in Molecular Biology, pp. 109-128, The Humana Press Inc., Clifton, NJ
26. Jiang, L., Huang, Y., Hunyor, S., and dos Remedios, C. G. (2003) Eur. Heart J. 24, 742-751
27. Shilkrut, M., Yaniv, G., Asleh, R., Levy, A. P., Larisch, S., and Binah, O. (2003) J. Mol. Cell Cardiol. 35, 1229-1240
28. Li, Y., Takemura, G., Kosai, K., Takahashi, T., Okada, H., Miyata, S., Yuge, K., Nagano, S., Esaki, M., Khai, N. C., Goto, K., Mikami, A., Maruyama, R., Minatoguchi, S., Fujiwara, T., and Fujiwara, H. (2004) Circ. Res. 95, 627-636
29. Li, Y., Song, Y. H., Mohler, J., and Delafontaine, P. (2006) Am. J. Physiol. Heart Circ. Physiol. 290, H2116-H2123
30. Suhara, T., Kim, H. S., Kirshenbaum, L. A., and Walsh, K. (2002) Mol. Cell Biol. 22, 680-691
31. Kurlawalla-Martinez, C., Stiles, B., Wang, Y., Devaskar, S. U., Kahn, B. B., and Wu, H. (2005) Mol. Cell Biol. 25, 2498-2510
32. Lo, T. L., Yusoff, P., Fong, C. W., Guo, K., McCaw, B. J., Phillips, W. A., Yang, H., Wong, E. S., Leong, H. F., Zeng, Q., Putti, T. C., and Guy, G. R. (2004) Cancer Res. 64, 6127-6136
33. Stiles, B., Wang, Y., Stahl, A., Bassilian, S., Lee, W. P., Kim, Y. J., Sherwin, R., Devaskar, S., Lesche, R., Magnuson, M. A., and Wu, H. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 2082-2087
34. Stiles, B. L., Kuralwalla-Martinez, C., Guo, W., Gregorian, C., Wang, Y., Tian, J., Magnuson, M. A., and Wu, H. (2006) Mol. Cell Biol. 26, 2772-2781
35. Wijesekara, N., Konrad, D., Eweida, M., Jefferies, C., Liadis, N., Giacca, A., Crackower, M., Suzuki, A., Mak, T. W., Kahn, C. R., Klip, A., and Woo, M. (2005) Mol. Cell Biol. 25, 1135-1145
36. Wong, J. T., Kim, P. T., Peacock, J. W., Yau, T. Y., Mui, A. L., Chung, S. W., Sossi, V., Doudet, D., Green, D., Ruth, T. J., Parsons, R., Verchere, C. B., and Ong, C. J. (2007) Diabetologia 50, 395-403
37. Yin, C., Salloum, F. N., and Kukreja, R. C. (2009) Circ. Res. 104, 572-575
38. Gibson, S., Tu, S., Oyer, R., Anderson, S. M., and Johnson, G. L. (1999) J. Biol. Chem. 274, 17612-17618
39. Schmid, T., Jansen, A. P., Baker, A. R., Hegamyer, G., Hagan, J. P., and Colburn, N. H. (2008) Cancer Res. 68, 1254-1260
40. Woodard, J., Sassano, A., Hay, N., and Platanias, L. C. (2008) Clin. Cancer Res. 14, 4640-4649
41. Rane, S., He, M., Sayed, D., Yan, L., Vatner, D., and Abdellatif, M. (2010) Cell Signal. 22, 1054-1062
42. Fukazawa, T., Fujiwara, T., Morimoto, Y., Shao, J., Nishizaki, M., Kadowaki, Y., Hizuta, A., Owen-Schaub, L. B., Roth, J. A., and Tanaka, N. (1999) Oncogene 18, 2189-2199
43. Rane, S., He, M., Sayed, D., Vashistha, H., Malhotra, A., Sadoshima, J., Vatner, D. E., Vatner, S. F., and Abdellatif, M. (2009) Circ. Res. 104, 879-886
44. Bracken, C. P., Gregory, P. A., Kolesnikoff, N., Bert, A. G., Wang, J., Shannon, M. F., and Goodall, G. J. (2008) Cancer Res. 68, 7846-7854
45. Packer, A. N., Xing, Y., Harper, S. Q., Jones, L., and Davidson, B. L. (2008) J. Neurosci. 28, 14341-14346
46. Xu, N., Papagiannakopoulos, T., Pan, G., Thomson, J. A., and Kosik, K. S. (2009) Cell 137, 647-658
47. Rybak, A., Fuchs, H., Smirnova, L., Brandt, C., Pohl, E. E., Nitsch, R., and Wulczyn, F. G. (2008) Nat. Cell Biol. 10, 987-993