Altered long noncoding RNA expression profiles in the myocardium of rats with ischemic heart failure

Journal of Cardiovascular Medicine

Volumn 16, Issue 7, 2015, Pages 473-479

  Gao, Wei ^a   Wang, Ze Mu ^a   Zhu, Meng ^a   Lian, Xiao Qing ^a   Zhao, Huan ^a   Zhao, Di ^a   Yang, Zhi Jian ^a   Lu, Xiang ^b   Wang, Lian Sheng ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Heart; Ischemic chronic heart failure; Long noncoding RNA; Profile; Rat

Indexed keywords

CITRATE SYNTHASE; CYCLIN DEPENDENT KINASE 2; IKBKB PROTEIN; LONG UNTRANSLATED RNA; MAP2K1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; SPACER DNA; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CHROMOSOME 1; CHROMOSOME 2; CHROMOSOME 3; CONTROLLED STUDY; DOWN REGULATION; EXON; GENE EXPRESSION; GENE ONTOLOGY; HEART FAILURE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; ISCHEMIC HEART FAILURE; MALE; MICROARRAY ANALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ANIMAL; CARDIAC MUSCLE; DISEASE MODEL; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENETIC PREDISPOSITION TO DISEASE; HEART FAILURE; MALE; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS, SPRAGUE-DAWLEY; RNA, LONG NONCODING; RNA, MESSENGER;

EID: 84942875031     PISSN: 15582027     EISSN: 15582035     Source Type: Journal    
DOI: 10.2459/JCM.0b013e32836499cd     Document Type: Article

References (28)

1. Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics - 2012 update: a report from the American Heart Association. Circulation 2012;125:e2-e220.
2. Mill JG, Stefanon I, dos Santos L, Baldo MP. Remodeling in the ischemic heart: the stepwise progression for heart failure. Braz J Med Biol Res 2011;44:890-898.
3. Guttman M, Amit I, Garber M, et al. Chromatin signature reveals over a thousand highly conserved large noncoding RNAs in mammals. Nature 2009;458:223-227.
4. Huang Y, Liu N, Wang JP, et al. Regulatory long noncoding RNA and its functions. J Physiol Biochem 2012;68:611-618.
5. Harries LW. Long noncoding RNAs and human disease. Biochem Soc Trans 2012;40:902-906.
6. Holdt LM, Beutner F, Scholz M, et al. ANRIL expression is associated with atherosclerosis risk at chromosome 9p21. Arterioscler Thromb Vasc Biol 2010;30:620-627.
7. Folkersen L, Kyriakou T, Goel A, et al. Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants. PLoS One 2009;4:e7677.
8. Ishii N, Ozaki K, Sato H, et al. Identification of a novel noncoding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet 2006;51:1087-1099.
9. Lee JH, Gao C, Peng G, et al. Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. Circ Res 2011;109:1332-1341.
10. Fukushima S, Varela-Carver A, Coppen SR, et al. Direct intramyocardial but not intracoronary injection of bone marrow cells induces ventricular arrhythmias in a rat chronic ischemic heart failure model. Circulation 2007;115:2254-2261.
11. Schonrock N, Harvey RP, Mattick JS. Long noncoding RNAs in cardiac development and pathophysiology. Circ Res 2012;111:1349-1362.
12. Podlowski S, Bramlage P, Baumann G, et al. Cardiac troponin I senseantisense RNA duplexes in the myocardium. J Cell Biochem 2002;85:198-207.
13. Haddad F, Qin AX, Bodell PW, et al. Regulation of antisense RNA expression during cardiac MHC gene switching in response to pressure overload. Am J Physiol Heart Circ Physiol 2006;290:H2351-H2361.
14. Ritter O, Haase H, Schulte HD, et al. Remodeling of the hypertrophied human myocardium by cardiac bHLH transcription factors. J Cell Biochem 1999;74:551-561.
15. Friedrichs F, Zugck C, Rauch GJ, et al. HBEGF, SRA1, and IK: three cosegregating genes as determinants of cardiomyopathy. Genome Res 2009;19:395-403.
16. Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell 2009;136:629-641.
17. Yap KL, Li S, Munoz-Cabello AM, et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 2010;38:662-674.
18. Visel A, Zhu Y, May D, et al. Targeted deletion of the 9p21 noncoding coronary artery disease risk interval in mice. Nature 2010;464:409-412.
19. Wakisaka Y, Niwano S, Niwano H, et al. Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure. Cardiovasc Res 2004;63:689-699.
20. Qiu H, Dai H, Jain K, et al. Characterization of a novel cardiac isoform of the cell cycle-related kinase that is regulated during heart failure. J Biol Chem 2008;283:22157-22165.
21. Kalsi KK, Smolenski RT, Pritchard RD, et al. Energetics and function of the failing human heart with dilated or hypertrophic cardiomyopathy. Eur J Clin Invest 1999;29:469-477.
22. Ibebuogu UN, Gladysheva IP, Houng AK, Reed GL. Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Circ Heart Fail 2011;4:114-120.
23. Rose BA, Force T, Wang Y. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010;90:1507-1546.
24. Chandrakala AN, Sukul D, Selvarajan K, et al. Induction of brain natriuretic peptide and monocyte chemotactic protein-1 gene expression by oxidized low-density lipoprotein: relevance to ischemic heart failure. Am J Physiol Cell Physiol 2012;302:C165-C177.
25. Portbury AL, Ronnebaum SM, Zungu M, et al. Back to your heart: ubiquitin proteasome system-regulated signal transduction. J Mol Cell Cardiol 2012;52:526-537.
26. Lim H, Zhu YZ. Role of transforming growth factor-beta in the progression of heart failure. Cell Mol Life Sci 2006;63:2584-2596.
27. Maier HJ, Schips TG, Wietelmann A, et al. Cardiomyocyte-specific IkappaB kinase (IKK)/NF-kappaB activation induces reversible inflammatory cardiomyopathy and heart failure. Proc Natl Acad Sci U S A 2012;109:11794-11799.
28. Wang J, Xu N, Feng X, et al. Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure. Circ Res 2005;97:821-828.