α7 Nicotinic Acetylcholine Receptor Relieves Angiotensin II-Induced Senescence in Vascular Smooth Muscle Cells by Raising Nicotinamide Adenine Dinucleotide-Dependent SIRT1 Activity

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 8, 2016, Pages 1566-1576

  Li, Dong Jie ^a   Huang, Fang ^a   Ni, Min ^a   Fu, Hui ^a   Zhang, Liang Sheng ^a   Shen, Fu Ming ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

angiotensin II; hypertension; lipid peroxidation; mice; reactive oxygen species

Indexed keywords

4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; ANGIOTENSIN II; BETA GALACTOSIDASE; BUNGAROTOXIN RECEPTOR; CHECKPOINT KINASE 1; CYCLINE; HISTONE H2A; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN P16; PROTEIN P21; PROTEIN P22; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SIRTUIN 1; CHRNA7 PROTEIN, HUMAN; CHRNA7 PROTEIN, MOUSE; CHRNA7 PROTEIN, RAT; HISTONE DEACETYLASE INHIBITOR; NICOTINIC AGENT; SIRT1 PROTEIN, HUMAN; SIRT1 PROTEIN, MOUSE; SIRT1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE ACTIVATION; GENE REPLICATION; GENE SILENCING; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SENESCENCE; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE CELL; WILD TYPE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL AGING; CELL CULTURE; CELL PROLIFERATION; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; GENOTYPE; HYPERTENSION; KNOCKOUT MOUSE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; RNA INTERFERENCE; SPRAGUE DAWLEY RAT; TIME FACTOR; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANGIOTENSIN II; ANIMALS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENOTYPE; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYPERTENSION; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NAD; NICOTINIC AGONISTS; OXIDATIVE STRESS; PHENOTYPE; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SIRTUIN 1; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84976291740     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307157     Document Type: Article

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