Vascular smooth muscle sirtuin-1 protects against aortic dissection during angiotensin II-induced hypertension

Journal of the American Heart Association

Volumn 4, Issue 9, 2015, Pages

  Fry, Jessica L ^a   Shiraishi, Yasunaga ^a   Turcotte, Raphaël ^b,c   Yu, Xunjie ^b   Gao, Yuan Z ^b   Akiki, Rachid ^a   Bachschmid, Markus ^a   Zhang, Yanhang ^b   Morgan, Kathleen G ^b   Cohen, Richard A ^a   Seta, Francesca ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Angiotensin II; Aortic dissection; Sirtuin 1; Vascular smooth muscle

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CRE RECOMBINASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 19; SIRTUIN 1; STROMELYSIN; TRANSGELIN; AMINE OXIDE; ELASTIN; MATRIX METALLOPROTEINASE; SCAVENGER; SIRT1 PROTEIN, MOUSE; SPIN LABEL; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA DISSECTION; ARTERIAL STIFFNESS; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; EX VIVO STUDY; GENE EXPRESSION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PROTECTION; HYPERTENSION; IN VIVO STUDY; INCIDENCE; MEAN ARTERIAL PRESSURE; MORTALITY RATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULSE WAVE; STOP CODON; VASCULAR SMOOTH MUSCLE; ANEURYSM, DISSECTING; ANIMAL; AORTIC ANEURYSM; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; ELASTIC TISSUE; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; SMOOTH MUSCLE CELL; THORACIC AORTA; TIME FACTOR;

ANEURYSM, DISSECTING; ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; AORTIC ANEURYSM; CELLS, CULTURED; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; ELASTIC TISSUE; ELASTIN; FREE RADICAL SCAVENGERS; HYPERTENSION; MATRIX METALLOPROTEINASES; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; SIRTUIN 1; SPIN LABELS; TIME FACTORS;

EID: 84991519757     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002384     Document Type: Article

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