Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

Cardiovascular Research

Volumn 103, Issue 4, 2014, Pages 485-497

  Alrob, Osama Abo ^a   Sankaralingam, Sowndramalingam ^a   Ma, Cary ^a   Wagg, Cory S ^a   Fillmore, Natasha ^a   Jaswal, Jagdip S ^a   Sack, Michael N ^b   Lehner, Richard ^a   Gupta, Mahesh P ^c   Michelakis, Evangelos D ^a   Padwal, Raj S ^a   Johnstone, David E ^a   Sharma, Arya M ^a   Lopaschuk, Gary D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Akt; B hydroxyacyl CoA dehydrogenase; Glucose oxidation; Long chain acyl CoA dehydrogenase; Lysine acetylation; Obesity; Sirtuin 3

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ACYLTRANSFERASE; GLUCOSE; INSULIN; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; LYSINE; MITOCHONDRIAL ENZYME; PROTEIN KINASE B; PYRUVATE DEHYDROGENASE; SIRTUIN 3; FATTY ACID; SIRT3 PROTEIN, MOUSE;

AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID OXIDATION; GLUCOSE OXIDATION; HEART; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; DEACETYLATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEART PERFUSION; LIPID DIET; LOW FAT DIET; NUCLEAR MAGNETIC RESONANCE IMAGING; ORAL GLUCOSE TOLERANCE TEST; 129 MOUSE; ACETYLATION; ANIMAL; C57BL MOUSE; GENETICS; HEART MUSCLE; KNOCKOUT MOUSE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ACETYLATION; ACYL-COA DEHYDROGENASE, LONG-CHAIN; ANIMALS; FATTY ACIDS; HEART; INSULIN; LYSINE; MALE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; OBESITY; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; SIRTUIN 3;

EID: 84907339466     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu156     Document Type: Article

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