A novel ligand conjugated nanoparticles for oral insulin delivery

Drug Delivery

Volumn 23, Issue 6, 2016, Pages 2015-2025

  Liu, Chong ^a   Shan, Wei ^a   Liu, Min ^a   Zhu, Xi ^a   Xu, Juan ^a   Xu, Yining ^a   Huang, Yuan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Caco 2 cells; integrin v 3 receptor; ligand FQSIYPpIK; nanoparticles; oral delivery

Indexed keywords

CHITOSAN DERIVATIVE; FQS PEPTIDE; GLUCOSE; MACROGOL; NANOCARRIER; PEPTIDE; PIG INSULIN; POLYGLACTIN; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; (LACTIDE-CO-GLYCOLIDE)-MONOMETHOXY-POLY(POLYETHYLENE GLYCOL); CHITOSAN; DRUG CARRIER; INSULIN; LIGAND; MACROGOL DERIVATIVE; MICELLE; N-TRIMETHYL CHITOSAN CHLORIDE; NANOPARTICLE;

ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CACO 2 CELL LINE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ABSORPTION; DRUG RELEASE; DRUG UPTAKE; ENDOCYTOSIS; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INTERNALIZATION; INTESTINE EPITHELIUM; INTRACELLULAR SIGNALING; NANOFABRICATION; NANOPHARMACEUTICS; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CACO-2 CELL LINE; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEM; MICELLE; ORAL DRUG ADMINISTRATION; PH; PROCEDURES;

ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; CHITOSAN; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGEN-ION CONCENTRATION; INSULIN; LIGANDS; MICELLES; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; RATS;

EID: 84975121694     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2015.1058433     Document Type: Article

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