Pulmonary delivered polymeric micelles - Pharmacokinetic evaluation and biodistribution studies

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 3, 2014, Pages 1064-1075

  Hu, Xiao ^a   Yang, Fei Fei ^a   Quan, Li Hui ^a   Liu, Chun Yu ^a   Liu, Xin Min ^a   Ehrhardt, Carsten ^b   Liao, Yong Hong ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Curcumin; Polymeric micelles; Pulmonary arterial hypertension (PAH); Pulmonary delivery; Sustained release; Translocation

Indexed keywords

CURCUMIN; CURCUMIN ACETATE; UNCLASSIFIED DRUG; MICELLE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PENETRATION; DRUG STABILITY; ENCAPSULATION; EVALUATION STUDY; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LASER DOPPLER FLOWMETRY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LUNG PARENCHYMA; MALE; MICELLE; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; POLYMERIZATION; PULMONARY ARTERY; RAT; SUSTAINED DRUG RELEASE; TISSUE DISTRIBUTION; VASCULAR ENDOTHELIUM; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; DRUG EFFECTS; DRUG SCREENING; LUNG; METABOLISM; PROCEDURES; WISTAR RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; LUNG; MALE; MICELLES; POLYMERS; RATS; RATS, WISTAR;

EID: 84912525231     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.10.010     Document Type: Article

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