Biotinylated liposomes as potential carriers for the oral delivery of insulin

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 1, 2014, Pages 167-176

  Zhang, Xingwang ^a   Qi, Jianping ^a   Lu, Yi ^a   He, Wei ^a   Li, Xiaoyang ^a   Wu, Wei ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Biotin; Insulin; Liposomes; Oral delivery; Receptor mediated endocytosis

Indexed keywords

BIOTIN; ENHANCED ABSORPTION; HYPOGLYCEMIC EFFECT; ORAL DELIVERY; PHYSICAL STABILITY; RECEPTOR-MEDIATED ENDOCYTOSIS; RELATIVE BIOAVAILABILITY; SOCIO-ECONOMIC IMPACTS;

ACYLATION; BIOCHEMISTRY; COENZYMES; INSULIN; MOLECULAR BIOLOGY; PHOSPHOLIPIDS;

LIPOSOMES;

BIOTINYLATED LIPOSOME; DRUG CARRIER; INSULIN; LIPOSOME; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; BIOTINYLATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; INSULIN BLOOD LEVEL; NONHUMAN; RAT;

RATTUS;

1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATIDYL ETHANOLAMINE; APPARENT PERMEABILITY; BIOTIN; BIOTINYLATED LIPOSOMES; BLPS; CD; CIRCULAR DICHROISM; CLPS; CLSM; CONFOCAL LASER SCANNING MICROSCOPE; CONVENTIONAL LIPOSOMES; DSPE; EE; ENTRAPMENT EFFICIENCY; FITC; FLUORESCENT ISOTHIOCYANATE; GASTROINTESTINAL; GI; INSULIN; LIPOSOMES; MEAN FLUORESCENCE INTENSITY; MFI; ORAL DELIVERY; P(APP); PA; PHARMACOLOGICAL BIOAVAILABILITY; PHASE TRANSITION TEMPERATURE; RECEPTOR-MEDIATED ENDOCYTOSIS; S.C; SGF; SIF; SIMULATED GASTRIC FLUID; SIMULATED INTESTINAL FLUID; SOYBEAN PHOSPHATIDYLCHOLINE; SPC; SUBCUTANEOUS; T(T); TEM; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; INSULIN; LIPOSOMES; RATS;

EID: 84891002990     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.07.011     Document Type: Article

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