메뉴 건너뛰기




Volumn 65, Issue 6, 2013, Pages 822-832

Nanoparticles for oral delivery: Targeted nanoparticles with peptidic ligands for oral protein delivery

Author keywords

GI tract; Nanoparticles; Oral protein delivery; Peptidic ligands; Protein absorption

Indexed keywords

GASTROINTESTINAL TRACT; GI TRACT; HIGH MOLECULAR WEIGHT; MEMBRANE PERMEABILITY; ORAL PROTEIN DELIVERY; PEPTIDIC LIGANDS; PROTEIN ABSORPTION; TARGETED NANOPARTICLE;

EID: 84878855642     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.10.007     Document Type: Review
Times cited : (382)

References (134)
  • 1
    • 33646492929 scopus 로고    scopus 로고
    • Tight junction modulation and its relationship to drug delivery
    • Salama N.N., Eddington N.D., Fasano A. Tight junction modulation and its relationship to drug delivery. Adv. Drug Deliv. Rev. 2006, 58:15-28.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 15-28
    • Salama, N.N.1    Eddington, N.D.2    Fasano, A.3
  • 2
    • 0030981739 scopus 로고    scopus 로고
    • Pharmacokinetic considerations of new insulin formulations and routes of administration
    • Hoffman A., Ziv E. Pharmacokinetic considerations of new insulin formulations and routes of administration. Clin. Pharmacokinet. 1997, 33:285-301.
    • (1997) Clin. Pharmacokinet. , vol.33 , pp. 285-301
    • Hoffman, A.1    Ziv, E.2
  • 3
    • 0036257686 scopus 로고    scopus 로고
    • Converting a peptide into a drug: strategies to improve stability and bioavailability
    • Adessi C., Soto C. Converting a peptide into a drug: strategies to improve stability and bioavailability. Curr. Med. Chem. 2002, 9:963-978.
    • (2002) Curr. Med. Chem. , vol.9 , pp. 963-978
    • Adessi, C.1    Soto, C.2
  • 4
    • 29744469461 scopus 로고    scopus 로고
    • Strategies to improve stability and bioavailability of peptide drugs
    • Adessi C., Soto C. Strategies to improve stability and bioavailability of peptide drugs. Front. Med. Chem. 2004, 1:513-527.
    • (2004) Front. Med. Chem. , vol.1 , pp. 513-527
    • Adessi, C.1    Soto, C.2
  • 5
    • 79551683531 scopus 로고    scopus 로고
    • Oral protein delivery: current status and future prospect
    • Park K., Kwon I.C., Park K. Oral protein delivery: current status and future prospect. React. Funct. Polym. 2011, 71:280-287.
    • (2011) React. Funct. Polym. , vol.71 , pp. 280-287
    • Park, K.1    Kwon, I.C.2    Park, K.3
  • 6
    • 0035940059 scopus 로고    scopus 로고
    • Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics
    • Hussain N., Jaitley V., Florence A.T. Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics. Adv. Drug Deliv. Rev. 2001, 50:107-142.
    • (2001) Adv. Drug Deliv. Rev. , vol.50 , pp. 107-142
    • Hussain, N.1    Jaitley, V.2    Florence, A.T.3
  • 7
    • 0025029073 scopus 로고
    • Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption
    • Donovan M.D., Flynn G.L., Amidon G.L. Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption. Pharm. Res. 1990, 7:863-868.
    • (1990) Pharm. Res. , vol.7 , pp. 863-868
    • Donovan, M.D.1    Flynn, G.L.2    Amidon, G.L.3
  • 8
    • 0027233875 scopus 로고
    • Degradation of proteins by guinea pig intestinal enzymes
    • Ikesue K., Kopečkovà P., Kopeček J. Degradation of proteins by guinea pig intestinal enzymes. Int. J. Pharm. 1993, 95:171-179.
    • (1993) Int. J. Pharm. , vol.95 , pp. 171-179
    • Ikesue, K.1    Kopečkovà, P.2    Kopeček, J.3
  • 9
    • 0022468493 scopus 로고
    • A new approach to the oral administration of insulin and other peptide drugs
    • Saffran M., Kumar G., Savariar C., Burnham J., Williams F., Neckers D. A new approach to the oral administration of insulin and other peptide drugs. Science 1986, 233:1081-1084.
    • (1986) Science , vol.233 , pp. 1081-1084
    • Saffran, M.1    Kumar, G.2    Savariar, C.3    Burnham, J.4    Williams, F.5    Neckers, D.6
  • 10
    • 0030460690 scopus 로고    scopus 로고
    • Oral controlled release technology for peptides: status and future prospects
    • Fix J.A. Oral controlled release technology for peptides: status and future prospects. Pharm. Res. 1996, 13:1760-1764.
    • (1996) Pharm. Res. , vol.13 , pp. 1760-1764
    • Fix, J.A.1
  • 11
    • 0036779424 scopus 로고    scopus 로고
    • Protein drug oral delivery: the recent progress
    • Lee H.J. Protein drug oral delivery: the recent progress. Arch. Pharm. Res. 2002, 25:572-584.
    • (2002) Arch. Pharm. Res. , vol.25 , pp. 572-584
    • Lee, H.J.1
  • 12
  • 13
    • 0028858297 scopus 로고
    • Nanoparticulate systems in drug delivery and targeting
    • Kreuter J. Nanoparticulate systems in drug delivery and targeting. J. Drug Target. 1995, 3:171-173.
    • (1995) J. Drug Target. , vol.3 , pp. 171-173
    • Kreuter, J.1
  • 14
    • 0031943571 scopus 로고    scopus 로고
    • Regulation of the movement of solutes across tight junctions
    • Madara J.L. Regulation of the movement of solutes across tight junctions. Annu. Rev. Physiol. 1998, 60:143-159.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 143-159
    • Madara, J.L.1
  • 15
    • 0023743080 scopus 로고
    • Enhancement of colonic drug absorption by the paracellular permeation route
    • Tomita M., Shiga M., Hayashi M., Awazu S. Enhancement of colonic drug absorption by the paracellular permeation route. Pharm. Res. 1988, 5:341-346.
    • (1988) Pharm. Res. , vol.5 , pp. 341-346
    • Tomita, M.1    Shiga, M.2    Hayashi, M.3    Awazu, S.4
  • 17
    • 0023520885 scopus 로고
    • Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters
    • Pappenheimer J.R. Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters. J. Membr. Biol. 1987, 100:137-148.
    • (1987) J. Membr. Biol. , vol.100 , pp. 137-148
    • Pappenheimer, J.R.1
  • 18
    • 0024310227 scopus 로고
    • Ionic permeation mechanisms in epithelia: biionic potentials, dilution potentials, conductances, and streaming potentials
    • Barry P.H. Ionic permeation mechanisms in epithelia: biionic potentials, dilution potentials, conductances, and streaming potentials. Methods Enzymol. 1989, 171:678-715.
    • (1989) Methods Enzymol. , vol.171 , pp. 678-715
    • Barry, P.H.1
  • 19
    • 0019631483 scopus 로고
    • Barrier function of epithelia
    • Powell D.W. Barrier function of epithelia. Am. J. Physiol. 1981, 241:G275-G288.
    • (1981) Am. J. Physiol. , vol.241
    • Powell, D.W.1
  • 20
    • 0037342777 scopus 로고    scopus 로고
    • Paracellular ion channel at the tight junction
    • Tang V.W., Goodenough D.A. Paracellular ion channel at the tight junction. Biophys. J. 2003, 84:1660-1673.
    • (2003) Biophys. J. , vol.84 , pp. 1660-1673
    • Tang, V.W.1    Goodenough, D.A.2
  • 21
    • 14544286414 scopus 로고    scopus 로고
    • Particle uptake by Peyer's patches: a pathway for drug and vaccine delivery
    • Shakweh M., Ponchel G., Fattal E. Particle uptake by Peyer's patches: a pathway for drug and vaccine delivery. Expert Opin. Drug Deliv. 2004, 1:141-163.
    • (2004) Expert Opin. Drug Deliv. , vol.1 , pp. 141-163
    • Shakweh, M.1    Ponchel, G.2    Fattal, E.3
  • 22
    • 2942702257 scopus 로고    scopus 로고
    • Issues in oral nanoparticle drug carrier uptake and targeting
    • Florence A.T. Issues in oral nanoparticle drug carrier uptake and targeting. J. Drug Target. 2004, 12:65-70.
    • (2004) J. Drug Target. , vol.12 , pp. 65-70
    • Florence, A.T.1
  • 23
    • 0026255075 scopus 로고
    • (B) Mechanisms of peptide and protein absorption: (2) transcellular mechanism of peptide and protein absorption: passive aspects
    • Burton P.S., Conradi R.A., Hilgers A.R. (B) Mechanisms of peptide and protein absorption: (2) transcellular mechanism of peptide and protein absorption: passive aspects. Adv. Drug Deliv. Rev. 1991, 7:365-385.
    • (1991) Adv. Drug Deliv. Rev. , vol.7 , pp. 365-385
    • Burton, P.S.1    Conradi, R.A.2    Hilgers, A.R.3
  • 25
    • 0029841664 scopus 로고    scopus 로고
    • M cells in Peyer's patches of the intestine
    • Academic Press, W.J. Kwang (Ed.)
    • Gebert A., Rothkötter H.-J., Pabst R. M cells in Peyer's patches of the intestine. Int. Rev. Cytol 1996, 91-159. Academic Press. W.J. Kwang (Ed.).
    • (1996) Int. Rev. Cytol , pp. 91-159
    • Gebert, A.1    Rothkötter, H.-J.2    Pabst, R.3
  • 26
    • 0031064037 scopus 로고    scopus 로고
    • Targeting of mucosal vaccines to Peyer's patch M cells
    • Frey A., Neutra M.R. Targeting of mucosal vaccines to Peyer's patch M cells. Behring Inst. Mitt. 1997, 98:376-389.
    • (1997) Behring Inst. Mitt. , vol.98 , pp. 376-389
    • Frey, A.1    Neutra, M.R.2
  • 27
    • 0034734982 scopus 로고    scopus 로고
    • Lectin-mediated mucosal delivery of drugs and microparticles
    • Clark M.A., Hirst B.H., Jepson M.A. Lectin-mediated mucosal delivery of drugs and microparticles. Adv. Drug Deliv. Rev. 2000, 43:207-223.
    • (2000) Adv. Drug Deliv. Rev. , vol.43 , pp. 207-223
    • Clark, M.A.1    Hirst, B.H.2    Jepson, M.A.3
  • 28
    • 7044222179 scopus 로고    scopus 로고
    • Use of fluorescence imaging to investigate the structure and function of intestinal M cells
    • Buda A., Sands C., Jepson M.A. Use of fluorescence imaging to investigate the structure and function of intestinal M cells. Adv. Drug Deliv. Rev. 2005, 57:123-134.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 123-134
    • Buda, A.1    Sands, C.2    Jepson, M.A.3
  • 29
    • 0026730479 scopus 로고
    • Further histological evidence of the gastrointestinal absorption of polystyrene nanospheres in the rat
    • Jani P.U., Florence A.T., McCarthy D.E. Further histological evidence of the gastrointestinal absorption of polystyrene nanospheres in the rat. Int. J. Pharm. 1992, 84:245-252.
    • (1992) Int. J. Pharm. , vol.84 , pp. 245-252
    • Jani, P.U.1    Florence, A.T.2    McCarthy, D.E.3
  • 30
    • 0024409936 scopus 로고
    • The association of gap junctions with large particles in the crypt epithelium of the rat small intestine
    • Kataoka K., Tabata J., Yamamoto M., Toyota T. The association of gap junctions with large particles in the crypt epithelium of the rat small intestine. Arch. Histol. Cytol. 1989, 52:81-86.
    • (1989) Arch. Histol. Cytol. , vol.52 , pp. 81-86
    • Kataoka, K.1    Tabata, J.2    Yamamoto, M.3    Toyota, T.4
  • 31
    • 0029411993 scopus 로고
    • The importance of gastrointestinal uptake of particles in the design of oral delivery systems
    • Lavelle E.C., Sharif S., Thomas N.W., Holland J., Davis S.S. The importance of gastrointestinal uptake of particles in the design of oral delivery systems. Adv. Drug Deliv. Rev. 1995, 18:5-22.
    • (1995) Adv. Drug Deliv. Rev. , vol.18 , pp. 5-22
    • Lavelle, E.C.1    Sharif, S.2    Thomas, N.W.3    Holland, J.4    Davis, S.S.5
  • 32
    • 0025018162 scopus 로고
    • Intestinal translocation of particulates - implications for drug and antigen delivery
    • O'Hagan D.T. Intestinal translocation of particulates - implications for drug and antigen delivery. Adv. Drug Deliv. Rev. 1990, 5:265-285.
    • (1990) Adv. Drug Deliv. Rev. , vol.5 , pp. 265-285
    • O'Hagan, D.T.1
  • 33
    • 0032784691 scopus 로고    scopus 로고
    • Regional differences in quinine absorption from the undisturbed human colon assessed using a timed release delivery system
    • Hebden J.M., Wilson C.G., Spiller R.C., Gilchrist P.J., Blackshaw E., Frier M.E., Perkins A.C. Regional differences in quinine absorption from the undisturbed human colon assessed using a timed release delivery system. Pharm. Res. 1999, 16:1087-1092.
    • (1999) Pharm. Res. , vol.16 , pp. 1087-1092
    • Hebden, J.M.1    Wilson, C.G.2    Spiller, R.C.3    Gilchrist, P.J.4    Blackshaw, E.5    Frier, M.E.6    Perkins, A.C.7
  • 34
    • 0345307519 scopus 로고    scopus 로고
    • Carrier-mediated transport, oral drug delivery
    • John Wiley & Sons, New York, NY, E. Mathiowitz (Ed.)
    • Russell-Jones G.J. Carrier-mediated transport, oral drug delivery. Encyclopedia of controlled drug delivery 1999, 1:173-184. John Wiley & Sons, New York, NY. E. Mathiowitz (Ed.).
    • (1999) Encyclopedia of controlled drug delivery , vol.1 , pp. 173-184
    • Russell-Jones, G.J.1
  • 35
    • 0033278620 scopus 로고    scopus 로고
    • Gastrointestinal absorption of drugs: methods and studies
    • Barthe L., Woodley J., Houin G. Gastrointestinal absorption of drugs: methods and studies. Fundam. Clin. Pharmacol. 1999, 13:154-168.
    • (1999) Fundam. Clin. Pharmacol. , vol.13 , pp. 154-168
    • Barthe, L.1    Woodley, J.2    Houin, G.3
  • 36
    • 0026758261 scopus 로고
    • Structural Specificity of Mucosal-Cell Transport and Metabolism of Peptide Drugs: Implication for Oral Peptide Drug Delivery
    • Bai J.P.F., Amidon G.L. Structural Specificity of Mucosal-Cell Transport and Metabolism of Peptide Drugs: Implication for Oral Peptide Drug Delivery. Pharm. Res. 1992, 9:969-978.
    • (1992) Pharm. Res. , vol.9 , pp. 969-978
    • Bai, J.P.F.1    Amidon, G.L.2
  • 37
    • 0030457349 scopus 로고    scopus 로고
    • Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells
    • Shah D., Shen W.C. Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells. J. Pharm. Sci. 1996, 85:1306-1311.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1306-1311
    • Shah, D.1    Shen, W.C.2
  • 38
    • 0030581092 scopus 로고    scopus 로고
    • The potential use of receptor-mediated endocytosis for oral drug delivery
    • Russell-Jones G.J. The potential use of receptor-mediated endocytosis for oral drug delivery. Adv. Drug Deliv. Rev. 1996, 20:83-97.
    • (1996) Adv. Drug Deliv. Rev. , vol.20 , pp. 83-97
    • Russell-Jones, G.J.1
  • 39
    • 0031777867 scopus 로고    scopus 로고
    • Recent advances in intestinal macromolecular drug delivery via receptor-mediated transport pathways
    • Swaan P.W. Recent advances in intestinal macromolecular drug delivery via receptor-mediated transport pathways. Pharm. Res. 1998, 15:826-834.
    • (1998) Pharm. Res. , vol.15 , pp. 826-834
    • Swaan, P.W.1
  • 40
    • 0343408485 scopus 로고    scopus 로고
    • Lipophilic prodrugs designed for intestinal lymphatic transport
    • Charman W.N., Porter C.J.H. Lipophilic prodrugs designed for intestinal lymphatic transport. Adv. Drug Deliv. Rev. 1996, 19:149-169.
    • (1996) Adv. Drug Deliv. Rev. , vol.19 , pp. 149-169
    • Charman, W.N.1    Porter, C.J.H.2
  • 41
    • 0029730138 scopus 로고    scopus 로고
    • Oral protein drug delivery
    • Wang W. Oral protein drug delivery. J. Drug Target. 1996, 4:195-232.
    • (1996) J. Drug Target. , vol.4 , pp. 195-232
    • Wang, W.1
  • 42
    • 0028657017 scopus 로고
    • Enzymatic barriers for GI peptide and protein delivery
    • Woodley J.F. Enzymatic barriers for GI peptide and protein delivery. Crit. Rev. Ther. Drug Carrier Syst. 1994, 11:61-95.
    • (1994) Crit. Rev. Ther. Drug Carrier Syst. , vol.11 , pp. 61-95
    • Woodley, J.F.1
  • 43
    • 84878826354 scopus 로고    scopus 로고
    • 10 - Oral delivery of proteins and peptides: concepts and applications
    • Elsevier, London, M. Ambikanandan (Ed.)
    • Patel G., Misra A. 10 - Oral delivery of proteins and peptides: concepts and applications. Challenges in Delivery of Therapeutic Genomics and Proteomics 2011, 481-529. Elsevier, London. M. Ambikanandan (Ed.).
    • (2011) Challenges in Delivery of Therapeutic Genomics and Proteomics , pp. 481-529
    • Patel, G.1    Misra, A.2
  • 46
    • 33845227980 scopus 로고
    • Regulation of gastrointestinal function
    • Lange Medical Publications, W.F. Ganong (Ed.)
    • Ganong W.F. Regulation of gastrointestinal function. Review of medical physiology 1983, 394-420. Lange Medical Publications. 12th ed. W.F. Ganong (Ed.).
    • (1983) Review of medical physiology , pp. 394-420
    • Ganong, W.F.1
  • 48
    • 0026579497 scopus 로고
    • Aminopeptidase activity in the jejunal and ileal Peyer's patches of the albino rabbit
    • Hayakawa E., Lee V.H. Aminopeptidase activity in the jejunal and ileal Peyer's patches of the albino rabbit. Pharm. Res. 1992, 9:535-540.
    • (1992) Pharm. Res. , vol.9 , pp. 535-540
    • Hayakawa, E.1    Lee, V.H.2
  • 49
    • 0014863832 scopus 로고
    • The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit
    • Skillman J.J., Gould S.A., Chung R.S., Silen W. The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit. Ann. Surg. 1970, 172:564-584.
    • (1970) Ann. Surg. , vol.172 , pp. 564-584
    • Skillman, J.J.1    Gould, S.A.2    Chung, R.S.3    Silen, W.4
  • 50
    • 0021220221 scopus 로고
    • The gastric mucosal barrier: structure of intercellular junctions in the dog
    • Meyer R.A., McGinley D., Posalaky Z. The gastric mucosal barrier: structure of intercellular junctions in the dog. J. Ultrastruct. Res. 1984, 86:192-201.
    • (1984) J. Ultrastruct. Res. , vol.86 , pp. 192-201
    • Meyer, R.A.1    McGinley, D.2    Posalaky, Z.3
  • 51
    • 0027670876 scopus 로고
    • The effect of gastro-intestinal mucus on drug absorption
    • MacAdam A. The effect of gastro-intestinal mucus on drug absorption. Adv. Drug Deliv. Rev. 1993, 11:201-220.
    • (1993) Adv. Drug Deliv. Rev. , vol.11 , pp. 201-220
    • MacAdam, A.1
  • 52
    • 0017912949 scopus 로고
    • Biosynthesis of mucus glycoprotein
    • Phelps C.F. Biosynthesis of mucus glycoprotein. Br. Med. Bull. 1978, 34:43-48.
    • (1978) Br. Med. Bull. , vol.34 , pp. 43-48
    • Phelps, C.F.1
  • 53
    • 0018826722 scopus 로고
    • Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection
    • Allen A., Garner A. Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection. Gut 1980, 21:249-262.
    • (1980) Gut , vol.21 , pp. 249-262
    • Allen, A.1    Garner, A.2
  • 54
    • 0035287318 scopus 로고    scopus 로고
    • Delivery systems for penetration enhancement of peptide and protein drugs: design considerations
    • Kompella U.B., Lee V.H. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv. Drug Deliv. Rev. 2001, 46:211-245.
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 211-245
    • Kompella, U.B.1    Lee, V.H.2
  • 55
    • 0019903597 scopus 로고
    • A simple method for measuring thickness of the mucus gel layer adherent to rat, frog and human gastric mucosa: influence of feeding, prostaglandin, N-acetylcysteine and other agents
    • Kerss S., Allen A., Garner A. A simple method for measuring thickness of the mucus gel layer adherent to rat, frog and human gastric mucosa: influence of feeding, prostaglandin, N-acetylcysteine and other agents. Clin. Sci. 1982, 63:187-195.
    • (1982) Clin. Sci. , vol.63 , pp. 187-195
    • Kerss, S.1    Allen, A.2    Garner, A.3
  • 56
    • 78649835810 scopus 로고    scopus 로고
    • Barrier properties of gastrointestinal mucus to nanoparticle transport
    • Crater J.S., Carrier R.L. Barrier properties of gastrointestinal mucus to nanoparticle transport. Macromol. Biosci. 2010, 10:1473-1483.
    • (2010) Macromol. Biosci. , vol.10 , pp. 1473-1483
    • Crater, J.S.1    Carrier, R.L.2
  • 57
    • 60149111908 scopus 로고    scopus 로고
    • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
    • Lai S.K., Wang Y.-Y., Hanes J. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv. Drug Deliv. Rev. 2009, 61:158-171.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 158-171
    • Lai, S.K.1    Wang, Y.-Y.2    Hanes, J.3
  • 58
    • 0024836302 scopus 로고
    • Penetration and enzymatic barriers to peptide and protein absorption
    • Lee V.H.L., Yamamoto A. Penetration and enzymatic barriers to peptide and protein absorption. Adv. Drug Deliv. Rev. 1989, 4:171-207.
    • (1989) Adv. Drug Deliv. Rev. , vol.4 , pp. 171-207
    • Lee, V.H.L.1    Yamamoto, A.2
  • 60
    • 76249115874 scopus 로고    scopus 로고
    • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
    • Lai S.K., Wang Y.-Y., Hida K., Cone R., Hanes J. Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses. Proc. Natl. Acad. Sci. U. S. A. 2010, 7:59603.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.7 , pp. 59603
    • Lai, S.K.1    Wang, Y.-Y.2    Hida, K.3    Cone, R.4    Hanes, J.5
  • 61
    • 77953807454 scopus 로고    scopus 로고
    • Traffic of poly(lactic acid) nanoparticulate vaccine vehicle from intestinal mucus to sub-epithelial immune competent cells
    • Primard C., Rochereau N., Luciani E., Genin C., Delair T., Paul S., Verrier B. Traffic of poly(lactic acid) nanoparticulate vaccine vehicle from intestinal mucus to sub-epithelial immune competent cells. Biomaterials 2010, 31:6060-6068.
    • (2010) Biomaterials , vol.31 , pp. 6060-6068
    • Primard, C.1    Rochereau, N.2    Luciani, E.3    Genin, C.4    Delair, T.5    Paul, S.6    Verrier, B.7
  • 62
    • 27144505483 scopus 로고    scopus 로고
    • Region-dependent role of the mucous/glycocalyx layers in insulin permeation across rat small intestinal membrane
    • Aoki Y., Morishita M., Asai K., Akikusa B., Hosoda S., Takayama K. Region-dependent role of the mucous/glycocalyx layers in insulin permeation across rat small intestinal membrane. Pharm. Res. 2005, 22:1854-1862.
    • (2005) Pharm. Res. , vol.22 , pp. 1854-1862
    • Aoki, Y.1    Morishita, M.2    Asai, K.3    Akikusa, B.4    Hosoda, S.5    Takayama, K.6
  • 63
    • 0027538539 scopus 로고
    • Site-dependent effect of aprotinin, sodium caprate, Na2EDTA and sodium glycocholate on intestinal absorption of insulin
    • Morishita M., Morishita I., Takayama K., Machida Y., Nagai T. Site-dependent effect of aprotinin, sodium caprate, Na2EDTA and sodium glycocholate on intestinal absorption of insulin. Biol. Pharm. Bull. 1993, 16:68-72.
    • (1993) Biol. Pharm. Bull. , vol.16 , pp. 68-72
    • Morishita, M.1    Morishita, I.2    Takayama, K.3    Machida, Y.4    Nagai, T.5
  • 64
    • 61349153560 scopus 로고    scopus 로고
    • Engineering Design and Molecular Dynamics of Mucoadhesive Drug Delivery Systems as Targeting Agents
    • Serra L., Josep D., Nicholas P. Engineering Design and Molecular Dynamics of Mucoadhesive Drug Delivery Systems as Targeting Agents. Eur. J. Pharm. Biopharm. 2009, 71:519-528.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 519-528
    • Serra, L.1    Josep, D.2    Nicholas, P.3
  • 66
    • 0027461945 scopus 로고
    • Immune response to nasal delivery of antigenically intact tetanus toxoid associated with poly(l-lactic acid) microspheres in rats, rabbits and guinea-pigs
    • Almeida A.J., Alpar H.O., Brown M.R. Immune response to nasal delivery of antigenically intact tetanus toxoid associated with poly(l-lactic acid) microspheres in rats, rabbits and guinea-pigs. J. Pharm. Pharmacol. 1993, 45:198-203.
    • (1993) J. Pharm. Pharmacol. , vol.45 , pp. 198-203
    • Almeida, A.J.1    Alpar, H.O.2    Brown, M.R.3
  • 67
    • 0028049676 scopus 로고
    • Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles
    • Maloy K.J., Donachie A.M., O'Hagan D.T., Mowat A.M. Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles. Immunology 1994, 81:661-667.
    • (1994) Immunology , vol.81 , pp. 661-667
    • Maloy, K.J.1    Donachie, A.M.2    O'Hagan, D.T.3    Mowat, A.M.4
  • 69
    • 33746565966 scopus 로고    scopus 로고
    • The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis
    • Emerich D.F., Thanos C.G. The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis. Biomol. Eng. 2006, 23:171-184.
    • (2006) Biomol. Eng. , vol.23 , pp. 171-184
    • Emerich, D.F.1    Thanos, C.G.2
  • 70
    • 21544458037 scopus 로고    scopus 로고
    • Subtractive chromatography for purification and recovery of nano-bioproducts
    • Jahanshahi M., Zhang Z., Lyddiatt A. Subtractive chromatography for purification and recovery of nano-bioproducts. IEE Proc. Nanobiotechnol. 2005, 152:121-126.
    • (2005) IEE Proc. Nanobiotechnol. , vol.152 , pp. 121-126
    • Jahanshahi, M.1    Zhang, Z.2    Lyddiatt, A.3
  • 73
    • 29144461657 scopus 로고    scopus 로고
    • Polymeric nanoparticles for oral delivery of drugs and vaccines: a critical evaluation of in vivo studies
    • Galindo-Rodriguez S.A., Allemann E., Fessi H., Doelker E. Polymeric nanoparticles for oral delivery of drugs and vaccines: a critical evaluation of in vivo studies. Crit. Rev. Ther. Drug Carrier Syst. 2005, 22:419-464.
    • (2005) Crit. Rev. Ther. Drug Carrier Syst. , vol.22 , pp. 419-464
    • Galindo-Rodriguez, S.A.1    Allemann, E.2    Fessi, H.3    Doelker, E.4
  • 74
    • 0030471901 scopus 로고    scopus 로고
    • Gastrointestinal uptake of biodegradable microparticles: effect of particle size
    • Desai M.P., Labhasetwar V., Amidon G.L., Levy R.J. Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm. Res. 1996, 13:1838-1845.
    • (1996) Pharm. Res. , vol.13 , pp. 1838-1845
    • Desai, M.P.1    Labhasetwar, V.2    Amidon, G.L.3    Levy, R.J.4
  • 76
    • 0034601281 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?
    • Jung T., Kamm W., Breitenbach A., Kaiserling E., Xiao J.X., Kissel T. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake?. Eur. J. Pharm. Biopharm. 2000, 50:147-160.
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , pp. 147-160
    • Jung, T.1    Kamm, W.2    Breitenbach, A.3    Kaiserling, E.4    Xiao, J.X.5    Kissel, T.6
  • 77
    • 0027432534 scopus 로고
    • Drug-loaded nanoparticles - preparation methods and drug targeting issues
    • Allemann E., Gurny R., Doelker E. Drug-loaded nanoparticles - preparation methods and drug targeting issues. Eur. J. Pharm. Biopharm. 1993, 39:173-191.
    • (1993) Eur. J. Pharm. Biopharm. , vol.39 , pp. 173-191
    • Allemann, E.1    Gurny, R.2    Doelker, E.3
  • 78
    • 0345084474 scopus 로고    scopus 로고
    • Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers
    • Quintanar-Guerrero D., Allemann E., Fessi H., Doelker E. Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers. Drug Dev. Ind. Pharm. 1998, 24:1113-1128.
    • (1998) Drug Dev. Ind. Pharm. , vol.24 , pp. 1113-1128
    • Quintanar-Guerrero, D.1    Allemann, E.2    Fessi, H.3    Doelker, E.4
  • 80
    • 0028203956 scopus 로고
    • Fate of [14C]poly(DL-lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice
    • Le Ray A.M., Vert M., Gautier J.C., Benoît J.P. Fate of [14C]poly(DL-lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice. Int. J. Pharm. 1994, 106:201-211.
    • (1994) Int. J. Pharm. , vol.106 , pp. 201-211
    • Le Ray, A.M.1    Vert, M.2    Gautier, J.C.3    Benoît, J.P.4
  • 81
    • 0029757133 scopus 로고    scopus 로고
    • Systemic delivery of peptides and proteins across absorptive mucosae
    • Sayani A.P., Chien Y.W. Systemic delivery of peptides and proteins across absorptive mucosae. Crit. Rev. Ther. Drug Carrier Syst. 1996, 13:85-184.
    • (1996) Crit. Rev. Ther. Drug Carrier Syst. , vol.13 , pp. 85-184
    • Sayani, A.P.1    Chien, Y.W.2
  • 83
    • 0037092957 scopus 로고    scopus 로고
    • Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice
    • Oldenborg P.A., Gresham H.D., Chen Y., Izui S., Lindberg F.P. Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice. Blood 2002, 99:3500-3504.
    • (2002) Blood , vol.99 , pp. 3500-3504
    • Oldenborg, P.A.1    Gresham, H.D.2    Chen, Y.3    Izui, S.4    Lindberg, F.P.5
  • 84
    • 0034734959 scopus 로고    scopus 로고
    • Ligand-mediated tissue specific drug delivery
    • Hussain N. Ligand-mediated tissue specific drug delivery. Adv. Drug Deliv. Rev. 2000, 43:95-100.
    • (2000) Adv. Drug Deliv. Rev. , vol.43 , pp. 95-100
    • Hussain, N.1
  • 85
    • 80054090725 scopus 로고    scopus 로고
    • Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand
    • Lee G.Y., Kim J.-H., Oh G.T., Lee B.-H., Kwon I.C., Kim I.-S. Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand. J. Control. Release 2011, 155:211-217.
    • (2011) J. Control. Release , vol.155 , pp. 211-217
    • Lee, G.Y.1    Kim, J.-H.2    Oh, G.T.3    Lee, B.-H.4    Kwon, I.C.5    Kim, I.-S.6
  • 86
    • 83355173904 scopus 로고    scopus 로고
    • Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
    • Jin Y., Song Y., Zhu X., Zhou D., Chen C., Zhang Z., Huang Y. Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport. Biomaterials 2012, 33:1573-1582.
    • (2012) Biomaterials , vol.33 , pp. 1573-1582
    • Jin, Y.1    Song, Y.2    Zhu, X.3    Zhou, D.4    Chen, C.5    Zhang, Z.6    Huang, Y.7
  • 88
    • 11044222650 scopus 로고    scopus 로고
    • Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    • Gupta A.K., Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005, 26:3995-4021.
    • (2005) Biomaterials , vol.26 , pp. 3995-4021
    • Gupta, A.K.1    Gupta, M.2
  • 89
    • 0028416238 scopus 로고
    • Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
    • Wagner E., Curiel D., Cotten M. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv. Drug Deliv. Rev. 1994, 14:113-135.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , pp. 113-135
    • Wagner, E.1    Curiel, D.2    Cotten, M.3
  • 90
    • 33750008791 scopus 로고    scopus 로고
    • The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer
    • Daniels T.R., Delgado T., Rodriguez J.A., Helguera G., Penichet M.L. The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. Clin. Immunol. 2006, 121:144-158.
    • (2006) Clin. Immunol. , vol.121 , pp. 144-158
    • Daniels, T.R.1    Delgado, T.2    Rodriguez, J.A.3    Helguera, G.4    Penichet, M.L.5
  • 91
    • 33750019824 scopus 로고    scopus 로고
    • The transferrin receptor part II: Targeted delivery of therapeutic agents into cancer cells
    • Daniels T.R., Delgado T., Helguera G., Penichet M.L. The transferrin receptor part II: Targeted delivery of therapeutic agents into cancer cells. Clin. Immunol. 2006, 121:159-176.
    • (2006) Clin. Immunol. , vol.121 , pp. 159-176
    • Daniels, T.R.1    Delgado, T.2    Helguera, G.3    Penichet, M.L.4
  • 92
    • 0036889760 scopus 로고    scopus 로고
    • Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway
    • Qian Z.M., Li H., Sun H., Ho K. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol. Rev. 2002, 54:561-587.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 561-587
    • Qian, Z.M.1    Li, H.2    Sun, H.3    Ho, K.4
  • 93
    • 0346787820 scopus 로고    scopus 로고
    • The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture
    • Berry C.C., Charles S., Wells S., Dalby M.J., Curtis A.S.G. The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. Int. J. Pharm. 2004, 269:211-225.
    • (2004) Int. J. Pharm. , vol.269 , pp. 211-225
    • Berry, C.C.1    Charles, S.2    Wells, S.3    Dalby, M.J.4    Curtis, A.S.G.5
  • 94
    • 3042850553 scopus 로고    scopus 로고
    • Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis
    • Gupta A.K., Berry C.C., Gupta M., Curtis A.S.G. Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis. IEEE Trans. Nanobioscience 2003, 2:255-261.
    • (2003) IEEE Trans. Nanobioscience , vol.2 , pp. 255-261
    • Gupta, A.K.1    Berry, C.C.2    Gupta, M.3    Curtis, A.S.G.4
  • 96
    • 0032514943 scopus 로고    scopus 로고
    • Albumin's role in steroid hormone action and the origins of vertebrates: is albumin an essential protein?
    • Baker M.E. Albumin's role in steroid hormone action and the origins of vertebrates: is albumin an essential protein?. FEBS Lett. 1998, 439:9-12.
    • (1998) FEBS Lett. , vol.439 , pp. 9-12
    • Baker, M.E.1
  • 97
    • 0029775681 scopus 로고    scopus 로고
    • RGD and other recognition sequences for integrins
    • Ruoslahti E. RGD and other recognition sequences for integrins. Annu. Rev. Cell. Dev. Bi. 1996, 12:697-715.
    • (1996) Annu. Rev. Cell. Dev. Bi. , vol.12 , pp. 697-715
    • Ruoslahti, E.1
  • 98
    • 24644480103 scopus 로고    scopus 로고
    • Characterization of surface-modified nanoparticles for in vivo biointeraction. A sedimentation field flow fractionation study
    • Andersson M., Fromell K., Gullberg E., Artursson P., Caldwell K.D. Characterization of surface-modified nanoparticles for in vivo biointeraction. A sedimentation field flow fractionation study. Anal. Chem. 2005, 77:5488-5493.
    • (2005) Anal. Chem. , vol.77 , pp. 5488-5493
    • Andersson, M.1    Fromell, K.2    Gullberg, E.3    Artursson, P.4    Caldwell, K.D.5
  • 99
    • 0041559949 scopus 로고    scopus 로고
    • RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
    • Hersel U., Dahmen C., Kessler H. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials 2003, 24:4385-4415.
    • (2003) Biomaterials , vol.24 , pp. 4385-4415
    • Hersel, U.1    Dahmen, C.2    Kessler, H.3
  • 100
    • 79955116335 scopus 로고    scopus 로고
    • Advantages of RGD peptides for directing cell association with biomaterials
    • Bellis S.L. Advantages of RGD peptides for directing cell association with biomaterials. Biomaterials 2011, 32:4205-4210.
    • (2011) Biomaterials , vol.32 , pp. 4205-4210
    • Bellis, S.L.1
  • 102
    • 0043062820 scopus 로고    scopus 로고
    • Surface-engineered nanoparticles for multiple ligand coupling
    • Gref R., Couvreur P., Barratt G., Mysiakine E. Surface-engineered nanoparticles for multiple ligand coupling. Biomaterials 2003, 24:4529-4537.
    • (2003) Biomaterials , vol.24 , pp. 4529-4537
    • Gref, R.1    Couvreur, P.2    Barratt, G.3    Mysiakine, E.4
  • 103
    • 4644292567 scopus 로고    scopus 로고
    • WGA-grafted PLGA-nanospheres: preparation and association with Caco-2 single cells
    • Weissenböck A., Wirth M., Gabor F. WGA-grafted PLGA-nanospheres: preparation and association with Caco-2 single cells. J. Control. Release 2004, 99:383-392.
    • (2004) J. Control. Release , vol.99 , pp. 383-392
    • Weissenböck, A.1    Wirth, M.2    Gabor, F.3
  • 104
    • 27744508956 scopus 로고    scopus 로고
    • Paclitaxel-loaded PLGA nanoparticles: potentiation of anticancer activity by surface conjugation with wheat germ agglutinin
    • Mo Y., Lim L.-Y. Paclitaxel-loaded PLGA nanoparticles: potentiation of anticancer activity by surface conjugation with wheat germ agglutinin. J. Control. Release 2005, 108:244-262.
    • (2005) J. Control. Release , vol.108 , pp. 244-262
    • Mo, Y.1    Lim, L.-Y.2
  • 105
    • 24344471360 scopus 로고    scopus 로고
    • Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate
    • Mo Y., Lim L.Y. Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate. J. Control. Release 2005, 107:30-42.
    • (2005) J. Control. Release , vol.107 , pp. 30-42
    • Mo, Y.1    Lim, L.Y.2
  • 106
    • 54449083850 scopus 로고    scopus 로고
    • Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles
    • Gao X., Wang T., Wu B., Chen J., Chen J., Yue Y., Dai N., Chen H., Jiang X. Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles. BBBC 2008, 377:35-40.
    • (2008) BBBC , vol.377 , pp. 35-40
    • Gao, X.1    Wang, T.2    Wu, B.3    Chen, J.4    Chen, J.5    Yue, Y.6    Dai, N.7    Chen, H.8    Jiang, X.9
  • 107
    • 18844389468 scopus 로고    scopus 로고
    • Cellular recognition of paclitaxel-loaded polymeric nanoparticles composed of poly(gamma-benzyl l-glutamate) and poly(ethylene glycol) diblock copolymer endcapped with galactose moiety
    • Jeong Y.I., Seo S.J., Park I.K., Lee H.C., Kang I.C., Akaike T., Cho C.S. Cellular recognition of paclitaxel-loaded polymeric nanoparticles composed of poly(gamma-benzyl l-glutamate) and poly(ethylene glycol) diblock copolymer endcapped with galactose moiety. Int. J. Pharm. 2005, 296:151-161.
    • (2005) Int. J. Pharm. , vol.296 , pp. 151-161
    • Jeong, Y.I.1    Seo, S.J.2    Park, I.K.3    Lee, H.C.4    Kang, I.C.5    Akaike, T.6    Cho, C.S.7
  • 108
    • 34548863653 scopus 로고    scopus 로고
    • Lectin-conjugated PLGA nanoparticles loaded with thymopentin: ex vivo bioadhesion and in vivo biodistribution
    • Yin Y., Chen D., Qiao M., Wei X., Hu H. Lectin-conjugated PLGA nanoparticles loaded with thymopentin: ex vivo bioadhesion and in vivo biodistribution. J. Control. Release 2007, 123:27-38.
    • (2007) J. Control. Release , vol.123 , pp. 27-38
    • Yin, Y.1    Chen, D.2    Qiao, M.3    Wei, X.4    Hu, H.5
  • 114
    • 0028899525 scopus 로고
    • Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins
    • Koivunen E., Wang B., Ruoslahti E. Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins. Biotechnology 1995, 13:265-270.
    • (1995) Biotechnology , vol.13 , pp. 265-270
    • Koivunen, E.1    Wang, B.2    Ruoslahti, E.3
  • 115
    • 0030940283 scopus 로고    scopus 로고
    • Alpha v integrins as receptors for tumor targeting by circulating ligands
    • Pasqualini R., Koivunen E., Ruoslahti E. Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat. Biotechnol. 1997, 15:542-546.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 116
    • 4143098147 scopus 로고    scopus 로고
    • In vitro Selection of a Peptide with High Selectivity for Cardiomyocytes in vivo
    • McGuire M.J., Samli K.N., Johnston S.A., Brown K.C. In vitro Selection of a Peptide with High Selectivity for Cardiomyocytes in vivo. J. Mol. Biol. 2004, 342:171-182.
    • (2004) J. Mol. Biol. , vol.342 , pp. 171-182
    • McGuire, M.J.1    Samli, K.N.2    Johnston, S.A.3    Brown, K.C.4
  • 117
    • 0027946232 scopus 로고
    • Isolation of a peptide antagonist to the thrombin receptor using phage display
    • Doorbar J., Winter G. Isolation of a peptide antagonist to the thrombin receptor using phage display. J. Mol. Biol. 1994, 244:361-369.
    • (1994) J. Mol. Biol. , vol.244 , pp. 361-369
    • Doorbar, J.1    Winter, G.2
  • 118
    • 33645213499 scopus 로고    scopus 로고
    • Isolation of multiple cell-binding ligands from different phage displayed-peptide libraries
    • Oyama T., Rombel I.T., Samli K.N., Zhou X., Brown K.C. Isolation of multiple cell-binding ligands from different phage displayed-peptide libraries. Biosens. Bioelectron. 2006, 21:1867-1875.
    • (2006) Biosens. Bioelectron. , vol.21 , pp. 1867-1875
    • Oyama, T.1    Rombel, I.T.2    Samli, K.N.3    Zhou, X.4    Brown, K.C.5
  • 119
    • 62649127577 scopus 로고    scopus 로고
    • PR_b-targeted PEGylated liposomes for prostate cancer therapy
    • Done D., Ashish G., Efrosini K. PR_b-targeted PEGylated liposomes for prostate cancer therapy. Langmuir 2008, 24:13518-13524.
    • (2008) Langmuir , vol.24 , pp. 13518-13524
    • Done, D.1    Ashish, G.2    Efrosini, K.3
  • 123
    • 0028166496 scopus 로고
    • Preparation and characterization of lectin-latex conjugates for specific bioadhesion
    • Irache J.M., Durrer C., Duchene D., Ponchel G. Preparation and characterization of lectin-latex conjugates for specific bioadhesion. Biomaterials 1994, 15:899-904.
    • (1994) Biomaterials , vol.15 , pp. 899-904
    • Irache, J.M.1    Durrer, C.2    Duchene, D.3    Ponchel, G.4
  • 124
    • 0030467140 scopus 로고    scopus 로고
    • Bioadhesion of lectin-latex conjugates to rat intestinal mucosa
    • Irache J.M., Durrer C., Duchene D., Ponchel G. Bioadhesion of lectin-latex conjugates to rat intestinal mucosa. Pharm. Res. 1996, 13:1716-1719.
    • (1996) Pharm. Res. , vol.13 , pp. 1716-1719
    • Irache, J.M.1    Durrer, C.2    Duchene, D.3    Ponchel, G.4
  • 126
    • 0032711921 scopus 로고    scopus 로고
    • Lectin-mediated transport of nanoparticles across Caco-2 and OK cells
    • Russell-Jones G.J., Veitch H., Arthur L. Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. Int. J. Pharm. 1999, 190:165-174.
    • (1999) Int. J. Pharm. , vol.190 , pp. 165-174
    • Russell-Jones, G.J.1    Veitch, H.2    Arthur, L.3
  • 127
    • 33750501785 scopus 로고    scopus 로고
    • Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin
    • Zhang N., Ping Q., Huang G., Xu W., Cheng Y., Han X. Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin. Int. J. Pharm. 2006, 327:153-159.
    • (2006) Int. J. Pharm. , vol.327 , pp. 153-159
    • Zhang, N.1    Ping, Q.2    Huang, G.3    Xu, W.4    Cheng, Y.5    Han, X.6
  • 128
    • 34447259574 scopus 로고    scopus 로고
    • Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: Preparation and characterization
    • Liu J., Gong T., Wang C., Zhong Z., Zhang Z. Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: Preparation and characterization. Int. J. Pharm. 2007, 340:153-162.
    • (2007) Int. J. Pharm. , vol.340 , pp. 153-162
    • Liu, J.1    Gong, T.2    Wang, C.3    Zhong, Z.4    Zhang, Z.5
  • 129
    • 79955007488 scopus 로고    scopus 로고
    • Cyclic RGD functionalized gold nanoparticles for tumor targeting
    • Leonardo M., Elena M.V.A., Carlo S., Daniela A. Cyclic RGD functionalized gold nanoparticles for tumor targeting. Bioconjug. Chem. 2011, 22:664-672.
    • (2011) Bioconjug. Chem. , vol.22 , pp. 664-672
    • Leonardo, M.1    Elena, M.V.A.2    Carlo, S.3    Daniela, A.4
  • 131
    • 23744483537 scopus 로고    scopus 로고
    • Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis
    • Kim W.J., Yockman J.W., Lee M., Jeong J.H., Kim Y.H., Kim S.W. Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis. J. Control. Release 2005, 106:224-234.
    • (2005) J. Control. Release , vol.106 , pp. 224-234
    • Kim, W.J.1    Yockman, J.W.2    Lee, M.3    Jeong, J.H.4    Kim, Y.H.5    Kim, S.W.6
  • 133
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • Ruoslahti E., Pierschbacher M.D. New perspectives in cell adhesion: RGD and integrins. Science 1987, 238:491-497.
    • (1987) Science , vol.238 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.D.2
  • 134
    • 0032527082 scopus 로고    scopus 로고
    • A novel method for surface modification to promote cell attachment to hydrophobic substrates
    • Neff J.A., Caldwell K.D., Tresco P.A. A novel method for surface modification to promote cell attachment to hydrophobic substrates. J. Biomed. Mater. Res. 1998, 40:511-519.
    • (1998) J. Biomed. Mater. Res. , vol.40 , pp. 511-519
    • Neff, J.A.1    Caldwell, K.D.2    Tresco, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.