Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease

PLoS Genetics

Volumn 12, Issue 5, 2016, Pages

  Chung, Chan ^a   Elrick, Matthew J ^a   Dell’Orco, James M ^a   Qin, Zhaohui S ^b   Kalyana Sundaram, Shanker ^a   Chinnaiyan, Arul M ^a   Shakkottai, Vikram G ^a   Lieberman, Andrew P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN BETA 1; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN 27; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEGENERATION; CELL LOSS; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; GENE; GENE DELETION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HSPB1 GENE; IN VITRO STUDY; IN VIVO STUDY; MOTOR DYSFUNCTION; MOUSE; NEUROPROTECTION; NIEMANN PICK DISEASE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PURKINJE CELL; ANIMAL; BIOSYNTHESIS; CEREBELLUM; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; NERVE CELL; NERVE DEGENERATION; NIEMANN-PICK DISEASE, TYPE C; PATHOLOGY;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CEREBELLUM; DISEASE MODELS, ANIMAL; HSP27 HEAT-SHOCK PROTEINS; HUMANS; MICE; NERVE DEGENERATION; NEURONS; NIEMANN-PICK DISEASE, TYPE C; PURKINJE CELLS; RNA, SMALL INTERFERING;

EID: 84974626075     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006042     Document Type: Article

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