Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is sufficient to mediate neurodegeneration

Human Molecular Genetics

Volumn 20, Issue 22, 2011, Pages 4440-4451

  Yu, Ting ^a   Shakkottai, Vikram G ^a   Chung, Chan ^a   Lieberman, Andrew P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PROTEIN NPC1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL LOSS; CELL TYPE; CENTRAL NERVOUS SYSTEM DISEASE; GENE DELETION; GLIOSIS; HISTOPATHOLOGY; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PURKINJE CELL; WEIGHT REDUCTION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; ELECTROPHYSIOLOGY; GENE DELETION; KAPLAN-MEIER ESTIMATE; MICE; MICE, MUTANT STRAINS; NEURODEGENERATIVE DISEASES; NIEMANN-PICK DISEASE, TYPE C; PROTEINS;

MUS;

EID: 80054918963     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr372     Document Type: Article

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