An essential postsynaptic role for the ubiquitin proteasome system in slow homeostatic synaptic plasticity in cultured hippocampal neurons

Neuroscience

Volumn 171, Issue 4, 2010, Pages 1016-1031

  Jakawich, S K ^a,b   Neely, R M ^b   Djakovic, S N ^c   Patrick, G N ^c   Sutton, M A ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

AMPA receptor; GluA1; GluA2; Miniature excitatory postsynaptic current (mEPSC); Protein degradation; Synaptic scaling

Indexed keywords

AMPA RECEPTOR; BICUCULLINE; PROTEASOME; TETRODOTOXIN; UBIQUITIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; HOMEOSTASIS; MINIATURE ENDPLATE POTENTIAL; NERVE CELL; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UBIQUITINATION;

ANIMALS; ANIMALS, NEWBORN; BICUCULLINE; CELLS, CULTURED; DRUG INTERACTIONS; ENZYME INHIBITORS; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA-A RECEPTOR ANTAGONISTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HOMEOSTASIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NEURONAL PLASTICITY; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TIME FACTORS; TRANSFECTION; UBIQUITIN;

EID: 78650173767     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.09.061     Document Type: Article

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