Cinnamaldehyde and allopurinol reduce fructose-induced cardiac inflammation and fibrosis by attenuating CD36-mediated TLR4/6-IRAK4/1 signaling to suppress NLRP3 inflammasome activation

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Kang, Lin Lin ^a   Zhang, Dong Mei ^a   Ma, Chun Hua ^a   Zhang, Jian Hua ^a   Jia, Ke Ke ^a   Liu, Jia Hui ^a   Wang, Rong ^a   Kong, Ling Dong ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; ALLOPURINOL; CD36 ANTIGEN; CINNAMALDEHYDE; CRYOPYRIN; INFLAMMASOME; IRAK4 PROTEIN, RAT; NLRP3 PROTEIN, RAT; PROTEIN SERINE THREONINE KINASE; TLR4 PROTEIN, RAT; TOLL LIKE RECEPTOR 4;

ANALOGS AND DERIVATIVES; ANIMAL; FIBROSIS; MALE; METABOLISM; MYOCARDITIS; OXIDATIVE STRESS; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ACROLEIN; ALLOPURINOL; ANIMALS; CD36 ANTIGENS; FIBROSIS; INFLAMMASOMES; MALE; MYOCARDITIS; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84974622946     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep27460     Document Type: Article

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