TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

Basic Research in Cardiology

Volumn 109, Issue 5, 2014, Pages

  Liu, Yi ^a   Lian, Kun ^a   Zhang, Lijian ^a   Wang, Rutao ^a   Yi, Fu ^a   Gao, Chao ^a   Xin, Chao ^a   Zhu, Di ^a   Li, Yan ^a   Yan, Wenjun ^a   Xiong, Lize ^a   Gao, Erhe ^b   Wang, Haichang ^a   Tao, Ling ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac microvascular endothelial cells; Ischemia reperfusion; NLRP3 inflammasome; TXNIP

Indexed keywords

CASPASE 3; CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; SMALL INTERFERING RNA; THIOREDOXIN INTERACTING PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INFLAMMASOME; THIOREDOXIN; TXNIP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL INFILTRATION; CONTROLLED STUDY; ENZYME RELEASE; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; DISEASE MODEL; ENDOTHELIUM CELL; GENETIC TRANSFECTION; HEART; METABOLISM; NICK END LABELING; PATHOLOGY; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; HEART; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMASOMES; MICE; MICE, INBRED C57BL; MYOCARDIAL REPERFUSION INJURY; REAL-TIME POLYMERASE CHAIN REACTION; THIOREDOXINS; TRANSFECTION;

EID: 84903866180     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-014-0415-z     Document Type: Article

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