Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: A randomized, double-blind, placebo-controlled trial

Stroke

Volumn 39, Issue 12, 2008, Pages 3303-3307

  Muir, Scott W ^a   Harrow, Craig ^a   Dawson, Jesse ^a,b   Lees, Kennedy R ^a   Weir, Christopher J ^b   Sattar, Naveed ^c   Walters, Matthew R ^a  

^a Acute Stroke Unit   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Stroke management; Uric acid; Xanthine oxidase

Indexed keywords

ALLOPURINOL; AZATHIOPRINE; C REACTIVE PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; PLACEBO; URIC ACID; WARFARIN; ANTIOXIDANT; BIOLOGICAL MARKER; IL6 PROTEIN, HUMAN; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

AGED; ARTICLE; ATTENUATION; CELL ADHESION; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROL GROUP; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; KRUSKAL WALLIS TEST; LOW DRUG DOSE; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; URIC ACID BLOOD LEVEL; VASCULARIZATION; BLOOD; BRAIN ISCHEMIA; COMPARATIVE STUDY; DRUG ANTAGONISM; INFLAMMATION; MIDDLE AGED; MULTICENTER STUDY;

AGED; AGED, 80 AND OVER; ALLOPURINOL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; C-REACTIVE PROTEIN; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MALE; MIDDLE AGED; URIC ACID; XANTHINE OXIDASE;

EID: 58149328542     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.519793     Document Type: Article

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