-
1
-
-
84867158927
-
Molecular pathogenesis of multiple myeloma and its premalignant precursor
-
Kuehl WM and Bergsagel PL. Molecular pathogenesis of multiple myeloma and its premalignant precursor. The Journal of clinical investigation. 2012; 122:3456-3463
-
(2012)
The Journal of clinical investigation
, vol.122
, pp. 3456-3463
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
2
-
-
84908604358
-
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma
-
Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, Kumar S, Hillengass J, Kastritis E, Richardson P, Landgren O, Paiva B, Dispenzieri A, Weiss B, LeLeu X, Zweegman S, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. The Lancet Oncology. 2014; 15:e538-548
-
(2014)
The Lancet Oncology
, vol.15
, pp. e538-e548
-
-
Rajkumar, S.V.1
Dimopoulos, M.A.2
Palumbo, A.3
Blade, J.4
Merlini, G.5
Mateos, M.V.6
Kumar, S.7
Hillengass, J.8
Kastritis, E.9
Richardson, P.10
Landgren, O.11
Paiva, B.12
Dispenzieri, A.13
Weiss, B.14
LeLeu, X.15
Zweegman, S.16
-
4
-
-
34547106018
-
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
-
Hideshima T, Mitsiades C, Tonon G, Richardson PG and Anderson KC. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nature reviews Cancer. 2007; 7:585-598
-
(2007)
Nature reviews Cancer
, vol.7
, pp. 585-598
-
-
Hideshima, T.1
Mitsiades, C.2
Tonon, G.3
Richardson, P.G.4
Anderson, K.C.5
-
6
-
-
84925230958
-
An oral proteasome inhibitor for multiple myeloma
-
Pratt G. An oral proteasome inhibitor for multiple myeloma. The Lancet Oncology. 2014; 15:1417-1418
-
(2014)
The Lancet Oncology
, vol.15
, pp. 1417-1418
-
-
Pratt, G.1
-
7
-
-
84908131467
-
Panobinostat for the treatment of multiple myeloma
-
Rajkumar SV. Panobinostat for the treatment of multiple myeloma. The Lancet Oncology. 2014; 15:1178-1179
-
(2014)
The Lancet Oncology
, vol.15
, pp. 1178-1179
-
-
Rajkumar, S.V.1
-
8
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF and Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414:105-111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
9
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S and Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature. 2007; 445:106-110
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
10
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D and Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature medicine. 1997; 3:730-737
-
(1997)
Nature medicine
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
12
-
-
66149175569
-
Identification of gastric cancer stem cells using the cell surface marker CD44
-
Takaishi S, Okumura T, Tu S, Wang SS, Shibata W, Vigneshwaran R, Gordon SA, Shimada Y and Wang TC. Identification of gastric cancer stem cells using the cell surface marker CD44. Stem cells. 2009; 27:1006-1020
-
(2009)
Stem cells
, vol.27
, pp. 1006-1020
-
-
Takaishi, S.1
Okumura, T.2
Tu, S.3
Wang, S.S.4
Shibata, W.5
Vigneshwaran, R.6
Gordon, S.A.7
Shimada, Y.8
Wang, T.C.9
-
14
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF and Simeone DM. Identification of pancreatic cancer stem cells. Cancer research. 2007; 67:1030-1037
-
(2007)
Cancer research
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
Wicha, M.7
Clarke, M.F.8
Simeone, D.M.9
-
15
-
-
67650632683
-
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
-
Majeti R, Chao MP, Alizadeh AA, Pang WW, Jaiswal S, Gibbs KD, Jr., van Rooijen N and Weissman IL. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell. 2009; 138:286-299
-
(2009)
Cell
, vol.138
, pp. 286-299
-
-
Majeti, R.1
Chao, M.P.2
Alizadeh, A.A.3
Pang, W.W.4
Jaiswal, S.5
Gibbs, K.D.6
van Rooijen, N.7
Weissman, I.L.8
-
16
-
-
1542283717
-
Characterization of clonogenic multiple myeloma cells
-
Matsui W, Huff CA, Wang Q, Malehorn MT, Barber J, Tanhehco Y, Smith BD, Civin CI and Jones RJ. Characterization of clonogenic multiple myeloma cells. Blood. 2004; 103:2332-2336
-
(2004)
Blood
, vol.103
, pp. 2332-2336
-
-
Matsui, W.1
Huff, C.A.2
Wang, Q.3
Malehorn, M.T.4
Barber, J.5
Tanhehco, Y.6
Smith, B.D.7
Civin, C.I.8
Jones, R.J.9
-
17
-
-
84871238560
-
CD19-CD45 low/-CD38 high/CD138+ plasma cells enrich for human tumorigenic myeloma cells
-
Kim D, Park CY, Medeiros BC and Weissman IL. CD19-CD45 low/-CD38 high/CD138+ plasma cells enrich for human tumorigenic myeloma cells. Leukemia. 2012; 26:2530-2537
-
(2012)
Leukemia
, vol.26
, pp. 2530-2537
-
-
Kim, D.1
Park, C.Y.2
Medeiros, B.C.3
Weissman, I.L.4
-
18
-
-
84872345792
-
Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma
-
Chaidos A, Barnes CP, Cowan G, May PC, Melo V, Hatjiharissi E, Papaioannou M, Harrington H, Doolittle H, Terpos E, Dimopoulos M, Abdalla S, Yarranton H, Naresh K, Foroni L, Reid A, et al. Clinical drug resistance linked to interconvertible phenotypic and functional states of tumor-propagating cells in multiple myeloma. Blood. 2013; 121:318-328
-
(2013)
Blood
, vol.121
, pp. 318-328
-
-
Chaidos, A.1
Barnes, C.P.2
Cowan, G.3
May, P.C.4
Melo, V.5
Hatjiharissi, E.6
Papaioannou, M.7
Harrington, H.8
Doolittle, H.9
Terpos, E.10
Dimopoulos, M.11
Abdalla, S.12
Yarranton, H.13
Naresh, K.14
Foroni, L.15
Reid, A.16
-
19
-
-
79551602468
-
Critical appraisal of the side population assay in stem cell and cancer stem cell research
-
Golebiewska A, Brons NH, Bjerkvig R and Niclou SP. Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell stem cell. 2011; 8:136-147
-
(2011)
Cell stem cell
, vol.8
, pp. 136-147
-
-
Golebiewska, A.1
Brons, N.H.2
Bjerkvig, R.3
Niclou, S.P.4
-
20
-
-
48349133869
-
Side population cells in human cancers
-
Wu C and Alman BA. Side population cells in human cancers. Cancer letters. 2008; 268:1-9
-
(2008)
Cancer letters
, vol.268
, pp. 1-9
-
-
Wu, C.1
Alman, B.A.2
-
21
-
-
38549132452
-
Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance
-
Matsui W, Wang Q, Barber JP, Brennan S, Smith BD, Borrello I, McNiece I, Lin L, Ambinder RF, Peacock C, Watkins DN, Huff CA and Jones RJ. Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer research. 2008; 68:190-197
-
(2008)
Cancer research
, vol.68
, pp. 190-197
-
-
Matsui, W.1
Wang, Q.2
Barber, J.P.3
Brennan, S.4
Smith, B.D.5
Borrello, I.6
McNiece, I.7
Lin, L.8
Ambinder, R.F.9
Peacock, C.10
Watkins, D.N.11
Huff, C.A.12
Jones, R.J.13
-
22
-
-
84869209212
-
Stemness of B-cell progenitors in multiple myeloma bone marrow
-
Boucher K, Parquet N, Widen R, Shain K, Baz R, Alsina M, Koomen J, Anasetti C, Dalton W and Perez LE. Stemness of B-cell progenitors in multiple myeloma bone marrow. Clinical cancer research. 2012; 18:6155-6168
-
(2012)
Clinical cancer research
, vol.18
, pp. 6155-6168
-
-
Boucher, K.1
Parquet, N.2
Widen, R.3
Shain, K.4
Baz, R.5
Alsina, M.6
Koomen, J.7
Anasetti, C.8
Dalton, W.9
Perez, L.E.10
-
23
-
-
53449085087
-
A unique threedimensional model for evaluating the impact of therapy on multiple myeloma
-
Kirshner J, Thulien KJ, Martin LD, Debes Marun C, Reiman T, Belch AR and Pilarski LM. A unique threedimensional model for evaluating the impact of therapy on multiple myeloma. Blood. 2008; 112:2935-2945
-
(2008)
Blood
, vol.112
, pp. 2935-2945
-
-
Kirshner, J.1
Thulien, K.J.2
Martin, L.D.3
Debes Marun, C.4
Reiman, T.5
Belch, A.R.6
Pilarski, L.M.7
-
24
-
-
0033570946
-
The proliferative potential of myeloma plasma cells manifest in the SCID-hu host
-
Yaccoby S and Epstein J. The proliferative potential of myeloma plasma cells manifest in the SCID-hu host. Blood. 1999; 94:3576-3582
-
(1999)
Blood
, vol.94
, pp. 3576-3582
-
-
Yaccoby, S.1
Epstein, J.2
-
25
-
-
8844264524
-
The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells
-
Yata K and Yaccoby S. The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells. Leukemia. 2004; 18:1891-1897
-
(2004)
Leukemia
, vol.18
, pp. 1891-1897
-
-
Yata, K.1
Yaccoby, S.2
-
26
-
-
84865862858
-
CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients
-
Hosen N, Matsuoka Y, Kishida S, Nakata J, Mizutani Y, Hasegawa K, Mugitani A, Ichihara H, Aoyama Y, Nishida S, Tsuboi A, Fujiki F, Tatsumi N, Nakajima H, Hino M, Kimura T, et al. CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients. Leukemia. 2012; 26:2135-2141
-
(2012)
Leukemia
, vol.26
, pp. 2135-2141
-
-
Hosen, N.1
Matsuoka, Y.2
Kishida, S.3
Nakata, J.4
Mizutani, Y.5
Hasegawa, K.6
Mugitani, A.7
Ichihara, H.8
Aoyama, Y.9
Nishida, S.10
Tsuboi, A.11
Fujiki, F.12
Tatsumi, N.13
Nakajima, H.14
Hino, M.15
Kimura, T.16
-
27
-
-
84863886613
-
CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype
-
Paino T, Ocio EM, Paiva B, San-Segundo L, Garayoa M, Gutierrez NC, Sarasquete ME, Pandiella A, Orfao A and San Miguel JF. CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype. Haematologica. 2012; 97:1110-1114
-
(2012)
Haematologica
, vol.97
, pp. 1110-1114
-
-
Paino, T.1
Ocio, E.M.2
Paiva, B.3
San-Segundo, L.4
Garayoa, M.5
Gutierrez, N.C.6
Sarasquete, M.E.7
Pandiella, A.8
Orfao, A.9
San Miguel, J.F.10
-
28
-
-
84857473351
-
Phenotypic detection of clonotypic B cells in multiple myeloma by specific immunoglobulin ligands reveals their rarity in multiple myeloma
-
Trepel M, Martens V, Doll C, Rahlff J, Gosch B, Loges S and Binder M. Phenotypic detection of clonotypic B cells in multiple myeloma by specific immunoglobulin ligands reveals their rarity in multiple myeloma. PloS one. 2012; 7:e31998
-
(2012)
PloS one
, vol.7
-
-
Trepel, M.1
Martens, V.2
Doll, C.3
Rahlff, J.4
Gosch, B.5
Loges, S.6
Binder, M.7
-
29
-
-
84857032554
-
The peripheral CD138+ population but not the CD138-population contains myeloma clonogenic cells in plasma cell leukaemia patients
-
Chiron D, Surget S, Maiga S, Bataille R, Moreau P, Le Gouill S, Amiot M and Pellat-Deceunynck C. The peripheral CD138+ population but not the CD138-population contains myeloma clonogenic cells in plasma cell leukaemia patients. British journal of haematology. 2012; 156:679-683
-
(2012)
British journal of haematology
, vol.156
, pp. 679-683
-
-
Chiron, D.1
Surget, S.2
Maiga, S.3
Bataille, R.4
Moreau, P.5
Le Gouill, S.6
Amiot, M.7
Pellat-Deceunynck, C.8
-
30
-
-
79955974540
-
Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications
-
Jakubikova J, Adamia S, Kost-Alimova M, Klippel S, Cervi D, Daley JF, Cholujova D, Kong SY, Leiba M, Blotta S, Ooi M, Delmore J, Laubach J, Richardson PG, Sedlak J, Anderson KC, et al. Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications. Blood. 2011; 117:4409-4419
-
(2011)
Blood
, vol.117
, pp. 4409-4419
-
-
Jakubikova, J.1
Adamia, S.2
Kost-Alimova, M.3
Klippel, S.4
Cervi, D.5
Daley, J.F.6
Cholujova, D.7
Kong, S.Y.8
Leiba, M.9
Blotta, S.10
Ooi, M.11
Delmore, J.12
Laubach, J.13
Richardson, P.G.14
Sedlak, J.15
Anderson, K.C.16
-
31
-
-
84887611170
-
Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma
-
Hajek R, Okubote SA and Svachova H. Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma. British journal of haematology. 2013; 163:551-564
-
(2013)
British journal of haematology
, vol.163
, pp. 551-564
-
-
Hajek, R.1
Okubote, S.A.2
Svachova, H.3
-
32
-
-
84898930013
-
Concise review: Defining and targeting myeloma stem cell-like cells
-
Abe M, Harada T and Matsumoto T. Concise review: Defining and targeting myeloma stem cell-like cells. Stem cells. 2014; 32:1067-1073
-
(2014)
Stem cells
, vol.32
, pp. 1067-1073
-
-
Abe, M.1
Harada, T.2
Matsumoto, T.3
-
33
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
Goodell MA, Brose K, Paradis G, Conner AS and Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. The Journal of experimental medicine. 1996; 183:1797-1806
-
(1996)
The Journal of experimental medicine
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
34
-
-
33645514001
-
A side order of stem cells: the SP phenotype
-
Challen GA and Little MH. A side order of stem cells: the SP phenotype. Stem cells. 2006; 24:3-12
-
(2006)
Stem cells
, vol.24
, pp. 3-12
-
-
Challen, G.A.1
Little, M.H.2
-
35
-
-
52349103400
-
Presence of Hoechst low side populations in multiple myeloma
-
Loh YS, Mo S, Brown RD, Yamagishi T, Yang S, Joshua DE, Roufogalis BD and Sze DM. Presence of Hoechst low side populations in multiple myeloma. Leukemia & lymphoma. 2008; 49:1813-1816
-
(2008)
Leukemia & lymphoma
, vol.49
, pp. 1813-1816
-
-
Loh, Y.S.1
Mo, S.2
Brown, R.D.3
Yamagishi, T.4
Yang, S.5
Joshua, D.E.6
Roufogalis, B.D.7
Sze, D.M.8
-
36
-
-
3042822246
-
Demystifying SP cell purification: viability, yield, and phenotype are defined by isolation parameters
-
Montanaro F, Liadaki K, Schienda J, Flint A, Gussoni E and Kunkel LM. Demystifying SP cell purification: viability, yield, and phenotype are defined by isolation parameters. Experimental cell research. 2004; 298:144-154
-
(2004)
Experimental cell research
, vol.298
, pp. 144-154
-
-
Montanaro, F.1
Liadaki, K.2
Schienda, J.3
Flint, A.4
Gussoni, E.5
Kunkel, L.M.6
-
37
-
-
33744997203
-
Thalidomide in elderly patients with multiple myeloma
-
author reply 1977-1978
-
Kusumi E, Matsumura T, Yuji K, Tanaka Y and Kami M. Thalidomide in elderly patients with multiple myeloma. Lancet. 2006; 367:1977; author reply 1977-1978
-
(2006)
Lancet
, vol.367
, pp. 1977
-
-
Kusumi, E.1
Matsumura, T.2
Yuji, K.3
Tanaka, Y.4
Kami, M.5
-
38
-
-
0033546823
-
Low-dose thalidomide seems to be effective in multiple myeloma
-
Larkin M. Low-dose thalidomide seems to be effective in multiple myeloma. Lancet. 1999; 354:925
-
(1999)
Lancet
, vol.354
, pp. 925
-
-
Larkin, M.1
-
39
-
-
78650303860
-
Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study
-
Cavo M, Tacchetti P, Patriarca F, Petrucci MT, Pantani L, Galli M, Di Raimondo F, Crippa C, Zamagni E, Palumbo A, Offidani M, Corradini P, Narni F, Spadano A, Pescosta N, Deliliers GL, et al. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet. 2010; 376:2075-2085
-
(2010)
Lancet
, vol.376
, pp. 2075-2085
-
-
Cavo, M.1
Tacchetti, P.2
Patriarca, F.3
Petrucci, M.T.4
Pantani, L.5
Galli, M.6
Di Raimondo, F.7
Crippa, C.8
Zamagni, E.9
Palumbo, A.10
Offidani, M.11
Corradini, P.12
Narni, F.13
Spadano, A.14
Pescosta, N.15
Deliliers, G.L.16
-
40
-
-
84920599743
-
Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma
-
Stewart AK, Rajkumar SV, Dimopoulos MA, Masszi T, Spicka I, Oriol A, Hajek R, Rosinol L, Siegel DS, Mihaylov GG, Goranova-Marinova V, Rajnics P, Suvorov A, Niesvizky R, Jakubowiak AJ, San-Miguel JF, et al. Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma. The New England journal of medicine. 2015; 372:142-152
-
(2015)
The New England journal of medicine
, vol.372
, pp. 142-152
-
-
Stewart, A.K.1
Rajkumar, S.V.2
Dimopoulos, M.A.3
Masszi, T.4
Spicka, I.5
Oriol, A.6
Hajek, R.7
Rosinol, L.8
Siegel, D.S.9
Mihaylov, G.G.10
Goranova-Marinova, V.11
Rajnics, P.12
Suvorov, A.13
Niesvizky, R.14
Jakubowiak, A.J.15
San-Miguel, J.F.16
-
41
-
-
84950996666
-
Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
-
Franqui-Machin R, Wendlandt EB, Janz S, Zhan F and Tricot G. Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction? Oncotarget. 2015 1; 6:40496-506. doi: 10.18632/oncotarget.5800
-
(2015)
Oncotarget
, vol.1
, Issue.6
, pp. 40496-40506
-
-
Franqui-Machin, R.1
Wendlandt, E.B.2
Janz, S.3
Zhan, F.4
Tricot, G.5
-
42
-
-
0027976530
-
Circulating monoclonal B cells expressing P glycoprotein may be a reservoir of multidrugresistant disease in multiple myeloma
-
Pilarski LM and Belch AR. Circulating monoclonal B cells expressing P glycoprotein may be a reservoir of multidrugresistant disease in multiple myeloma. Blood. 1994; 83:724-736
-
(1994)
Blood
, vol.83
, pp. 724-736
-
-
Pilarski, L.M.1
Belch, A.R.2
-
43
-
-
0032968977
-
Analysis of circulating tumor cells in patients with multiple myeloma during the course of high-dose therapy with peripheral blood stem cell transplantation
-
Kiel K, Cremer FW, Rottenburger C, Kallmeyer C, Ehrbrecht E, Atzberger A, Hegenbart U, Goldschmidt H and Moos M. Analysis of circulating tumor cells in patients with multiple myeloma during the course of high-dose therapy with peripheral blood stem cell transplantation. Bone marrow transplantation. 1999; 23:1019-1027
-
(1999)
Bone marrow transplantation
, vol.23
, pp. 1019-1027
-
-
Kiel, K.1
Cremer, F.W.2
Rottenburger, C.3
Kallmeyer, C.4
Ehrbrecht, E.5
Atzberger, A.6
Hegenbart, U.7
Goldschmidt, H.8
Moos, M.9
-
44
-
-
0032821233
-
Clonotypic CD20+ and CD19+ B cells in peripheral blood of patients with multiple myeloma post high-dose therapy and peripheral blood stem cell transplantation
-
Rottenburger C, Kiel K, Bosing T, Cremer FW, Moldenhauer G, Ho AD, Goldschmidt H and Moos M. Clonotypic CD20+ and CD19+ B cells in peripheral blood of patients with multiple myeloma post high-dose therapy and peripheral blood stem cell transplantation. British journal of haematology. 1999; 106:545-552
-
(1999)
British journal of haematology
, vol.106
, pp. 545-552
-
-
Rottenburger, C.1
Kiel, K.2
Bosing, T.3
Cremer, F.W.4
Moldenhauer, G.5
Ho, A.D.6
Goldschmidt, H.7
Moos, M.8
-
46
-
-
84886819205
-
RARalpha2 expression confers myeloma stem cell features
-
Yang Y, Shi J, Tolomelli G, Xu H, Xia J, Wang H, Zhou W, Zhou Y, Das S, Gu Z, Levasseur D, Zhan F and Tricot G. RARalpha2 expression confers myeloma stem cell features. Blood. 2013; 122:1437-1447
-
(2013)
Blood
, vol.122
, pp. 1437-1447
-
-
Yang, Y.1
Shi, J.2
Tolomelli, G.3
Xu, H.4
Xia, J.5
Wang, H.6
Zhou, W.7
Zhou, Y.8
Das, S.9
Gu, Z.10
Levasseur, D.11
Zhan, F.12
Tricot, G.13
-
47
-
-
84961289380
-
Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma
-
Yang Y, Shi J, Gu Z, Salama ME, Das S, Wendlandt E, Xu H, Huang J, Tao Y, Hao M, Franqui R, Levasseur D, Janz S, Tricot G and Zhan F. Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma. Cancer research. 2015; 75:594-604
-
(2015)
Cancer research
, vol.75
, pp. 594-604
-
-
Yang, Y.1
Shi, J.2
Gu, Z.3
Salama, M.E.4
Das, S.5
Wendlandt, E.6
Xu, H.7
Huang, J.8
Tao, Y.9
Hao, M.10
Franqui, R.11
Levasseur, D.12
Janz, S.13
Tricot, G.14
Zhan, F.15
-
48
-
-
84875583581
-
Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1
-
Hawley TS, Riz I, Yang W, Wakabayashi Y, Depalma L, Chang YT, Peng W, Zhu J and Hawley RG. Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1. American journal of hematology. 2013; 88:265-272
-
(2013)
American journal of hematology
, vol.88
, pp. 265-272
-
-
Hawley, T.S.1
Riz, I.2
Yang, W.3
Wakabayashi, Y.4
Depalma, L.5
Chang, Y.T.6
Peng, W.7
Zhu, J.8
Hawley, R.G.9
-
49
-
-
4644306516
-
A distinct "side population" of cells with high drug efflux capacity in human tumor cells
-
Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA and Brenner MK. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101:14228-14233
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
Nuchtern, J.G.4
Jax, T.W.5
Gobel, U.6
Goodell, M.A.7
Brenner, M.K.8
-
50
-
-
79955593909
-
Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform
-
Marcato P, Dean CA, Giacomantonio CA and Lee PW. Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform. Cell cycle. 2011; 10:1378-1384
-
(2011)
Cell cycle
, vol.10
, pp. 1378-1384
-
-
Marcato, P.1
Dean, C.A.2
Giacomantonio, C.A.3
Lee, P.W.4
-
51
-
-
18744411547
-
Aplastic anaemia
-
Brodsky RA and Jones RJ. Aplastic anaemia. Lancet. 2005; 365:1647-1656
-
(2005)
Lancet
, vol.365
, pp. 1647-1656
-
-
Brodsky, R.A.1
Jones, R.J.2
-
52
-
-
77956302698
-
Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers
-
Deng S, Yang X, Lassus H, Liang S, Kaur S, Ye Q, Li C, Wang LP, Roby KF, Orsulic S, Connolly DC, Zhang Y, Montone K, Butzow R, Coukos G and Zhang L. Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers. PloS one. 2010; 5:e10277
-
(2010)
PloS one
, vol.5
-
-
Deng, S.1
Yang, X.2
Lassus, H.3
Liang, S.4
Kaur, S.5
Ye, Q.6
Li, C.7
Wang, L.P.8
Roby, K.F.9
Orsulic, S.10
Connolly, D.C.11
Zhang, Y.12
Montone, K.13
Butzow, R.14
Coukos, G.15
Zhang, L.16
-
53
-
-
84930019376
-
Aldehyde Dehydrogenase Is Regulated by beta-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells
-
Cojoc M, Peitzsch C, Kurth I, Trautmann F, Kunz-Schughart LA, Telegeev GD, Stakhovsky EA, Walker JR, Simin K, Lyle S, Fuessel S, Erdmann K, Wirth MP, Krause M, Baumann M and Dubrovska A. Aldehyde Dehydrogenase Is Regulated by beta-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells. Cancer research. 2015; 75:1482-1494
-
(2015)
Cancer research
, vol.75
, pp. 1482-1494
-
-
Cojoc, M.1
Peitzsch, C.2
Kurth, I.3
Trautmann, F.4
Kunz-Schughart, L.A.5
Telegeev, G.D.6
Stakhovsky, E.A.7
Walker, J.R.8
Simin, K.9
Lyle, S.10
Fuessel, S.11
Erdmann, K.12
Wirth, M.P.13
Krause, M.14
Baumann, M.15
Dubrovska, A.16
-
54
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS and Dontu G. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell stem cell. 2007; 1:555-567
-
(2007)
Cell stem cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
Brown, M.6
Jacquemier, J.7
Viens, P.8
Kleer, C.G.9
Liu, S.10
Schott, A.11
Hayes, D.12
Birnbaum, D.13
Wicha, M.S.14
Dontu, G.15
-
55
-
-
84899964003
-
ALDH1 activity identifies tumor-initiating cells and links to chromosomal instability signatures in multiple myeloma
-
Zhou W, Yang Y, Gu Z, Wang H, Xia J, Wu X, Zhan X, Levasseur D, Zhou Y, Janz S, Tricot G, Shi J and Zhan F. ALDH1 activity identifies tumor-initiating cells and links to chromosomal instability signatures in multiple myeloma. Leukemia. 2014; 28:1155-1158
-
(2014)
Leukemia
, vol.28
, pp. 1155-1158
-
-
Zhou, W.1
Yang, Y.2
Gu, Z.3
Wang, H.4
Xia, J.5
Wu, X.6
Zhan, X.7
Levasseur, D.8
Zhou, Y.9
Janz, S.10
Tricot, G.11
Shi, J.12
Zhan, F.13
-
56
-
-
84920054095
-
NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma
-
Yang Y, Zhou W, Xia J, Gu Z, Wendlandt E, Zhan X, Janz S, Tricot G and Zhan F. NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. Oncotarget. 2014; 5:11986-11997. doi: 10.18632/oncotarget.2388
-
(2014)
Oncotarget
, vol.5
, pp. 11986-11997
-
-
Yang, Y.1
Zhou, W.2
Xia, J.3
Gu, Z.4
Wendlandt, E.5
Zhan, X.6
Janz, S.7
Tricot, G.8
Zhan, F.9
-
57
-
-
67449113764
-
Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers
-
Tanei T, Morimoto K, Shimazu K, Kim SJ, Tanji Y, Taguchi T, Tamaki Y and Noguchi S. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. Clinical cancer research. 2009; 15:4234-4241
-
(2009)
Clinical cancer research
, vol.15
, pp. 4234-4241
-
-
Tanei, T.1
Morimoto, K.2
Shimazu, K.3
Kim, S.J.4
Tanji, Y.5
Taguchi, T.6
Tamaki, Y.7
Noguchi, S.8
-
59
-
-
85047688749
-
The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation
-
Raha D, Wilson TR, Peng J, Peterson D, Yue P, Evangelista M, Wilson C, Merchant M and Settleman J. The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation. Cancer research. 2014; 74:3579-3590
-
(2014)
Cancer research
, vol.74
, pp. 3579-3590
-
-
Raha, D.1
Wilson, T.R.2
Peng, J.3
Peterson, D.4
Yue, P.5
Evangelista, M.6
Wilson, C.7
Merchant, M.8
Settleman, J.9
-
60
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T, Rodrigues N, Shen H, Yang Y, Dombkowski D, Sykes M and Scadden DT. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science. 2000; 287:1804-1808
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
Rodrigues, N.2
Shen, H.3
Yang, Y.4
Dombkowski, D.5
Sykes, M.6
Scadden, D.T.7
-
61
-
-
77953229444
-
Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells
-
Fuhler GM, Baanstra M, Chesik D, Somasundaram R, Seckinger A, Hose D, Peppelenbosch MP and Bos NA. Bone marrow stromal cell interaction reduces syndecan-1 expression and induces kinomic changes in myeloma cells. Experimental cell research. 2010; 316:1816-1828
-
(2010)
Experimental cell research
, vol.316
, pp. 1816-1828
-
-
Fuhler, G.M.1
Baanstra, M.2
Chesik, D.3
Somasundaram, R.4
Seckinger, A.5
Hose, D.6
Peppelenbosch, M.P.7
Bos, N.A.8
-
62
-
-
39749178390
-
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
-
Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM and Scadden DT. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell stem cell. 2008; 2:274-283
-
(2008)
Cell stem cell
, vol.2
, pp. 274-283
-
-
Fleming, H.E.1
Janzen, V.2
Lo Celso, C.3
Guo, J.4
Leahy, K.M.5
Kronenberg, H.M.6
Scadden, D.T.7
-
63
-
-
84938209433
-
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
-
Takebe N, Miele L, Harris PJ, Jeong W, Bando H, Kahn M, Yang SX and Ivy SP. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nature reviews Clinical oncology. 2015; 12:445-464
-
(2015)
Nature reviews Clinical oncology
, vol.12
, pp. 445-464
-
-
Takebe, N.1
Miele, L.2
Harris, P.J.3
Jeong, W.4
Bando, H.5
Kahn, M.6
Yang, S.X.7
Ivy, S.P.8
-
64
-
-
84915745083
-
NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells
-
Zhao D, Mo Y, Li MT, Zou SW, Cheng ZL, Sun YP, Xiong Y, Guan KL and Lei QY. NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells. The Journal of clinical investigation. 2014; 124:5453-5465
-
(2014)
The Journal of clinical investigation
, vol.124
, pp. 5453-5465
-
-
Zhao, D.1
Mo, Y.2
Li, M.T.3
Zou, S.W.4
Cheng, Z.L.5
Sun, Y.P.6
Xiong, Y.7
Guan, K.L.8
Lei, Q.Y.9
-
65
-
-
84923283486
-
Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation
-
Hirata N, Yamada S, Shoda T, Kurihara M, Sekino Y and Kanda Y. Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation. Nature communications. 2014; 5:4806
-
(2014)
Nature communications
, vol.5
, pp. 4806
-
-
Hirata, N.1
Yamada, S.2
Shoda, T.3
Kurihara, M.4
Sekino, Y.5
Kanda, Y.6
-
66
-
-
84945573758
-
PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth
-
Sharma N, Nanta R, Sharma J, Gunewardena S, Singh KP, Shankar S and Srivastava RK. PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth. Oncotarget. 2015; 6:32039-32060. doi: 10.18632/oncotarget.5055
-
(2015)
Oncotarget
, vol.6
, pp. 32039-32060
-
-
Sharma, N.1
Nanta, R.2
Sharma, J.3
Gunewardena, S.4
Singh, K.P.5
Shankar, S.6
Srivastava, R.K.7
-
68
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T and Clevers H. Wnt signalling in stem cells and cancer. Nature. 2005; 434:843-850
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
69
-
-
30544450976
-
WNT/betacatenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells
-
Hao J, Li TG, Qi X, Zhao DF and Zhao GQ. WNT/betacatenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells. Developmental biology. 2006; 290:81-91
-
(2006)
Developmental biology
, vol.290
, pp. 81-91
-
-
Hao, J.1
Li, T.G.2
Qi, X.3
Zhao, D.F.4
Zhao, G.Q.5
-
70
-
-
11144355390
-
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
-
Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, van der Neut R, Spaargaren M and Pals ST. Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101:6122-6127
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
Tjin, E.2
Meijer, H.P.3
Klok, M.D.4
MacGillavry, H.D.5
van Oers, M.H.6
Lokhorst, H.M.7
Bloem, A.C.8
Clevers, H.9
Nusse, R.10
van der Neut, R.11
Spaargaren, M.12
Pals, S.T.13
-
71
-
-
34250678970
-
Targeting the betacatenin/TCF transcriptional complex in the treatment of multiple myeloma
-
Sukhdeo K, Mani M, Zhang Y, Dutta J, Yasui H, Rooney MD, Carrasco DE, Zheng M, He H, Tai YT, Mitsiades C, Anderson KC and Carrasco DR. Targeting the betacatenin/TCF transcriptional complex in the treatment of multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104:7516-7521
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 7516-7521
-
-
Sukhdeo, K.1
Mani, M.2
Zhang, Y.3
Dutta, J.4
Yasui, H.5
Rooney, M.D.6
Carrasco, D.E.7
Zheng, M.8
He, H.9
Tai, Y.T.10
Mitsiades, C.11
Anderson, K.C.12
Carrasco, D.R.13
-
72
-
-
84896532358
-
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/beta-catenin/BCL9 pathway
-
Zhao JJ, Lin J, Zhu D, Wang X, Brooks D, Chen M, Chu ZB, Takada K, Ciccarelli B, Admin S, Tao J, Tai YT, Treon S, Pinkus G, Kuo WP, Hideshima T, et al. miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/beta-catenin/BCL9 pathway. Cancer research. 2014; 74:1801-1813
-
(2014)
Cancer research
, vol.74
, pp. 1801-1813
-
-
Zhao, J.J.1
Lin, J.2
Zhu, D.3
Wang, X.4
Brooks, D.5
Chen, M.6
Chu, Z.B.7
Takada, K.8
Ciccarelli, B.9
Admin, S.10
Tao, J.11
Tai, Y.T.12
Treon, S.13
Pinkus, G.14
Kuo, W.P.15
Hideshima, T.16
-
73
-
-
84886879974
-
Targeting hedgehog signaling in cancer: research and clinical developments
-
Xie J, Bartels CM, Barton SW and Gu D. Targeting hedgehog signaling in cancer: research and clinical developments. OncoTargets and therapy. 2013; 6:1425-1435
-
(2013)
OncoTargets and therapy
, vol.6
, pp. 1425-1435
-
-
Xie, J.1
Bartels, C.M.2
Barton, S.W.3
Gu, D.4
-
74
-
-
77950826827
-
Multiple myeloma: a paradigm for translation of the cancer stem cell hypothesis
-
Agarwal JR and Matsui W. Multiple myeloma: a paradigm for translation of the cancer stem cell hypothesis. Anticancer agents in medicinal chemistry. 2010; 10:116-120
-
(2010)
Anticancer agents in medicinal chemistry
, vol.10
, pp. 116-120
-
-
Agarwal, J.R.1
Matsui, W.2
-
75
-
-
84866365997
-
Molecular pathways: the hedgehog signaling pathway in cancer
-
McMillan R and Matsui W. Molecular pathways: the hedgehog signaling pathway in cancer. Clinical cancer research. 2012; 18:4883-4888
-
(2012)
Clinical cancer research
, vol.18
, pp. 4883-4888
-
-
McMillan, R.1
Matsui, W.2
-
77
-
-
34247192972
-
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma
-
Peacock CD, Wang Q, Gesell GS, Corcoran-Schwartz IM, Jones E, Kim J, Devereux WL, Rhodes JT, Huff CA, Beachy PA, Watkins DN and Matsui W. Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104:4048-4053
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 4048-4053
-
-
Peacock, C.D.1
Wang, Q.2
Gesell, G.S.3
Corcoran-Schwartz, I.M.4
Jones, E.5
Kim, J.6
Devereux, W.L.7
Rhodes, J.T.8
Huff, C.A.9
Beachy, P.A.10
Watkins, D.N.11
Matsui, W.12
-
78
-
-
84907276398
-
A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance
-
Liu Z, Xu J, He J, Zheng Y, Li H, Lu Y, Qian J, Lin P, Weber DM, Yang J and Yi Q. A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance. Blood. 2014; 124:2061-2071
-
(2014)
Blood
, vol.124
, pp. 2061-2071
-
-
Liu, Z.1
Xu, J.2
He, J.3
Zheng, Y.4
Li, H.5
Lu, Y.6
Qian, J.7
Lin, P.8
Weber, D.M.9
Yang, J.10
Yi, Q.11
-
79
-
-
1942425110
-
Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines
-
Nefedova Y, Cheng P, Alsina M, Dalton WS and Gabrilovich DI. Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines. Blood. 2004; 103:3503-3510
-
(2004)
Blood
, vol.103
, pp. 3503-3510
-
-
Nefedova, Y.1
Cheng, P.2
Alsina, M.3
Dalton, W.S.4
Gabrilovich, D.I.5
-
80
-
-
11144358653
-
Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells
-
Jundt F, Probsting KS, Anagnostopoulos I, Muehlinghaus G, Chatterjee M, Mathas S, Bargou RC, Manz R, Stein H and Dorken B. Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. Blood. 2004; 103:3511-3515
-
(2004)
Blood
, vol.103
, pp. 3511-3515
-
-
Jundt, F.1
Probsting, K.S.2
Anagnostopoulos, I.3
Muehlinghaus, G.4
Chatterjee, M.5
Mathas, S.6
Bargou, R.C.7
Manz, R.8
Stein, H.9
Dorken, B.10
-
81
-
-
57849158165
-
Notch inhibition blocks multiple myeloma cell-induced osteoclast activation
-
Schwarzer R, Kaiser M, Acikgoez O, Heider U, Mathas S, Preissner R, Sezer O, Doerken B and Jundt F. Notch inhibition blocks multiple myeloma cell-induced osteoclast activation. Leukemia. 2008; 22:2273-2277
-
(2008)
Leukemia
, vol.22
, pp. 2273-2277
-
-
Schwarzer, R.1
Kaiser, M.2
Acikgoez, O.3
Heider, U.4
Mathas, S.5
Preissner, R.6
Sezer, O.7
Doerken, B.8
Jundt, F.9
-
82
-
-
4944230728
-
Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion
-
Abe M, Hiura K, Wilde J, Shioyasono A, Moriyama K, Hashimoto T, Kido S, Oshima T, Shibata H, Ozaki S, Inoue D and Matsumoto T. Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion. Blood. 2004; 104:2484-2491
-
(2004)
Blood
, vol.104
, pp. 2484-2491
-
-
Abe, M.1
Hiura, K.2
Wilde, J.3
Shioyasono, A.4
Moriyama, K.5
Hashimoto, T.6
Kido, S.7
Oshima, T.8
Shibata, H.9
Ozaki, S.10
Inoue, D.11
Matsumoto, T.12
-
83
-
-
41349095228
-
Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy
-
Nefedova Y, Sullivan DM, Bolick SC, Dalton WS and Gabrilovich DI. Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy. Blood. 2008; 111:2220-2229
-
(2008)
Blood
, vol.111
, pp. 2220-2229
-
-
Nefedova, Y.1
Sullivan, D.M.2
Bolick, S.C.3
Dalton, W.S.4
Gabrilovich, D.I.5
-
84
-
-
84880272654
-
Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1
-
Mirandola L, Apicella L, Colombo M, Yu Y, Berta DG, Platonova N, Lazzari E, Lancellotti M, Bulfamante G, Cobos E, Chiriva-Internati M and Chiaramonte R. Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1. Leukemia. 2013; 27:1558-1566
-
(2013)
Leukemia
, vol.27
, pp. 1558-1566
-
-
Mirandola, L.1
Apicella, L.2
Colombo, M.3
Yu, Y.4
Berta, D.G.5
Platonova, N.6
Lazzari, E.7
Lancellotti, M.8
Bulfamante, G.9
Cobos, E.10
Chiriva-Internati, M.11
Chiaramonte, R.12
-
85
-
-
84916899853
-
Notch signaling drives multiple myeloma induced osteoclastogenesis
-
Colombo M, Thummler K, Mirandola L, Garavelli S, Todoerti K, Apicella L, Lazzari E, Lancellotti M, Platonova N, Akbar M, Chiriva-Internati M, Soutar R, Neri A, Goodyear CS and Chiaramonte R. Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget. 2014; 5:10393-10406. doi: 10.18632/oncotarget.2084
-
(2014)
Oncotarget
, vol.5
, pp. 10393-10406
-
-
Colombo, M.1
Thummler, K.2
Mirandola, L.3
Garavelli, S.4
Todoerti, K.5
Apicella, L.6
Lazzari, E.7
Lancellotti, M.8
Platonova, N.9
Akbar, M.10
Chiriva-Internati, M.11
Soutar, R.12
Neri, A.13
Goodyear, C.S.14
Chiaramonte, R.15
-
86
-
-
84944554065
-
Identify multiple myeloma stem cells: Utopia?
-
Saltarella I, Lamanuzzi A, Reale A, Vacca A and Ria R. Identify multiple myeloma stem cells: Utopia? World journal of stem cells. 2015; 7:84-95
-
(2015)
World journal of stem cells
, vol.7
, pp. 84-95
-
-
Saltarella, I.1
Lamanuzzi, A.2
Reale, A.3
Vacca, A.4
Ria, R.5
-
87
-
-
0037158513
-
Activation of NFkappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
-
Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG and Anderson KC. Activation of NFkappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene. 2002; 21:5673-5683
-
(2002)
Oncogene
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
Schlossman, R.4
Akiyama, M.5
Chauhan, D.6
Hideshima, T.7
Treon, S.P.8
Munshi, N.C.9
Richardson, P.G.10
Anderson, K.C.11
-
89
-
-
84920973530
-
PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells
-
Kolev VN, Wright QG, Vidal CM, Ring JE, Shapiro IM, Ricono J, Weaver DT, Padval MV, Pachter JA and Xu Q. PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells. Cancer research. 2015; 75:446-455. doi: 10.18632/oncotarget.3802
-
(2015)
Cancer research
, vol.75
, pp. 446-455
-
-
Kolev, V.N.1
Wright, Q.G.2
Vidal, C.M.3
Ring, J.E.4
Shapiro, I.M.5
Ricono, J.6
Weaver, D.T.7
Padval, M.V.8
Pachter, J.A.9
Xu, Q.10
-
90
-
-
84934300731
-
MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma
-
Du J, Liu S, He J, Liu X, Qu Y, Yan W, Fan J, Li R, Xi H, Fu W, Zhang C, Yang J and Hou J. MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma. Oncotarget. 2015; 6:14993-15007
-
(2015)
Oncotarget
, vol.6
, pp. 14993-15007
-
-
Du, J.1
Liu, S.2
He, J.3
Liu, X.4
Qu, Y.5
Yan, W.6
Fan, J.7
Li, R.8
Xi, H.9
Fu, W.10
Zhang, C.11
Yang, J.12
Hou, J.13
-
91
-
-
84919842021
-
MicroRNAs in cancer stem cells: current status and future directions
-
Chhabra R and Saini N. MicroRNAs in cancer stem cells: current status and future directions. Tumour biology. 2014; 35:8395-8405
-
(2014)
Tumour biology
, vol.35
, pp. 8395-8405
-
-
Chhabra, R.1
Saini, N.2
-
92
-
-
84950996666
-
Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
-
Franqui-Machin R, Wendlandt EB, Janz S, Zhan F and Tricot G. Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction? Oncotarget. 2015; 6:40496-40506. doi: 10.18632/oncotarget.5800
-
(2015)
Oncotarget
, vol.6
, pp. 40496-40506
-
-
Franqui-Machin, R.1
Wendlandt, E.B.2
Janz, S.3
Zhan, F.4
Tricot, G.5
-
93
-
-
0035880256
-
Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
-
Podar K, Tai YT, Davies FE, Lentzsch S, Sattler M, Hideshima T, Lin BK, Gupta D, Shima Y, Chauhan D, Mitsiades C, Raje N, Richardson P and Anderson KC. Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration. Blood. 2001; 98:428-435
-
(2001)
Blood
, vol.98
, pp. 428-435
-
-
Podar, K.1
Tai, Y.T.2
Davies, F.E.3
Lentzsch, S.4
Sattler, M.5
Hideshima, T.6
Lin, B.K.7
Gupta, D.8
Shima, Y.9
Chauhan, D.10
Mitsiades, C.11
Raje, N.12
Richardson, P.13
Anderson, K.C.14
-
96
-
-
21244460271
-
Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression
-
Asosingh K, De Raeve H, de Ridder M, Storme GA, Willems A, Van Riet I, Van Camp B and Vanderkerken K. Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression. Haematologica. 2005; 90:810-817
-
(2005)
Haematologica
, vol.90
, pp. 810-817
-
-
Asosingh, K.1
De Raeve, H.2
de Ridder, M.3
Storme, G.A.4
Willems, A.5
Van Riet, I.6
Van Camp, B.7
Vanderkerken, K.8
-
97
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R and Friend SH. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002; 415:530-536
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van't Veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
Peterse, H.L.7
van der Kooy, K.8
Marton, M.J.9
Witteveen, A.T.10
Schreiber, G.J.11
Kerkhoven, R.M.12
Roberts, C.13
Linsley, P.S.14
Bernards, R.15
Friend, S.H.16
-
98
-
-
11144358111
-
Prognostically useful gene-expression profiles in acute myeloid leukemia
-
Valk PJ, Verhaak RG, Beijen MA, Erpelinck CA, Barjesteh van Waalwijk van Doorn-Khosrovani S, Boer JM, Beverloo HB, Moorhouse MJ, van der Spek PJ, Lowenberg B and Delwel R. Prognostically useful gene-expression profiles in acute myeloid leukemia. The New England journal of medicine. 2004; 350:1617-1628
-
(2004)
The New England journal of medicine
, vol.350
, pp. 1617-1628
-
-
Valk, P.J.1
Verhaak, R.G.2
Beijen, M.A.3
Erpelinck, C.A.4
Barjesteh van Waalwijk van Doorn-Khosrovani, S.5
Boer, J.M.6
Beverloo, H.B.7
Moorhouse, M.J.8
van der Spek, P.J.9
Lowenberg, B.10
Delwel, R.11
-
99
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C and Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005; 121:1109-1121
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
Yilmaz, O.H.4
Terhorst, C.5
Morrison, S.J.6
|