NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells

Journal of Clinical Investigation

Volumn 124, Issue 12, 2014, Pages 5453-5465

  Zhao, Di ^a,b,c   Mo, Yan ^a,b,c   Li, Meng Tian ^a,b,c   Zou, Shao Wu ^d   Cheng, Zhou Li ^a,b,c   Sun, Yi Ping ^a,b,c   Xiong, Yue ^b,c,e   Guan, Kun Liang ^a,b,f   Lei, Qun Ying ^a,b  

^a FUDAN UNIVERSITY   (China)

^b Institutes of Biomedical Sciences   (China)

^c FUDAN UNIVERSITY   (China)

^d TONGJI UNIVERSITY   (China)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE 1A1; ALDEHYDE DEHYDROGENASE ISOENZYME 1; HISTONE ACETYLTRANSFERASE PCAF; NICOTINAMIDE; NOTCH RECEPTOR; SIRTUIN 2; TRICHOSTATIN A; UNCLASSIFIED DRUG; ALDEHYDE DEHYDROGENASE; ALDH1A1 PROTEIN, HUMAN; P300-CBP-ASSOCIATED FACTOR; SIRT2 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER STEM CELL; CARCINOGENESIS; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CELL SUSPENSION; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN STABILITY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ACETYLATION; ANIMAL; BREAST TUMOR; CLINICAL TRIAL; GENETICS; METABOLISM; MUTATION; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE;

ACETYLATION; ALDEHYDE DEHYDROGENASE; ANIMALS; BREAST NEOPLASMS; FEMALE; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; MUTATION; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; P300-CBP TRANSCRIPTION FACTORS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SIRTUIN 2;

EID: 84915745083     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76611     Document Type: Article

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