Regulation of the P450 oxygenation cascade involved in glycopeptide antibiotic biosynthesis

Journal of the American Chemical Society

Volumn 138, Issue 21, 2016, Pages 6746-6753

  Peschke, Madeleine ^a   Haslinger, Kristina ^a,c   Brieke, Clara ^a   Reinstein, Jochen ^a   Cryle, Max J ^a,b  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^b MONASH UNIVERSITY   (Australia)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; ASSOCIATION REACTIONS; BIOCHEMISTRY; BIOSYNTHESIS; CATALYSIS; CATALYST ACTIVITY; CYCLIZATION; ENZYMES; REACTION KINETICS;

CATALYZED REACTIONS; CONFORMATIONAL CHANGE; GLYCOPEPTIDE ANTIBIOTICS; NONRIBOSOMAL PEPTIDE; NONRIBOSOMAL PEPTIDE SYNTHETASES; SPECIFIC RECOGNITION; STEADY-STATE KINETICS; TEICOPLANIN AGLYCONE;

PEPTIDES;

AGLYCONE; CYTOCHROME P450; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYPEPTIDE ANTIBIOTIC AGENT; TEICOPLANIN; ANTIINFECTIVE AGENT; GLYCOPEPTIDE; OXYGEN; PEPTIDE SYNTHASE; PROTEIN BINDING;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CYCLIZATION; ENZYME SUBSTRATE; OXIDATION KINETICS; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; REGULATORY MECHANISM; STEADY STATE; STEREOCHEMISTRY; BIOSYNTHESIS; CHEMISTRY;

ANTI-BACTERIAL AGENTS; BINDING SITES; CYCLIZATION; CYTOCHROME P-450 ENZYME SYSTEM; GLYCOPEPTIDES; OXYGEN; PEPTIDE SYNTHASES; PROTEIN BINDING;

EID: 84973301114     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b00307     Document Type: Article

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